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P. Timpson · SciRah

Researcher profile · Semantic Scholar

P. Timpson

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P. Timpson — researcher profile on SciRah

h-index: 65
Works: 310
Citations: 14K

Most-cited papers

Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
Sunny Z. Wu, D. Roden, Chenfei Wang, Holly Holliday +28 more
2020EMBO Journal372 citations Open access
Semantic Scholar
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
M. McDonald, Weng-Hua Khoo, P. Ng, Ya Xiao +43 more
2021Cell367 citations Open access
Semantic Scholar
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis
M. Papanicolaou, Amelia L. Parker, Michelle Yam, E. Filipe +26 more
2022Nature Communications182 citations Open access
Semantic Scholar
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
Monisha Samuel, P. Fonseka, Rahul Sanwlani, L. Gangoda +36 more
2021Nature Communications167 citations Open access
Semantic Scholar
Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer
Cecilia R. Chambers, Shona Ritchie, Brooke A. Pereira, P. Timpson
2021Molecular Oncology143 citations Open access
Semantic Scholar
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer
Jessica L. Chitty, Michelle Yam, L. Perryman, Amelia L. Parker +126 more
2023Nature Cancer132 citations Open access
Semantic Scholar
Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress
Noa Lamm, M. Read, Max Nobis, David Van Ly +5 more
2020Nature Cell Biology131 citations Open access
Semantic Scholar
Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition
G. Sharbeen, J. McCarroll, Anouschka Akerman, C. Kopecky +35 more
2020Cancer Research96 citations Open access
Semantic Scholar
Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes
S. Ghoroghi, B. Mary, A. Larnicol, N. Asokan +24 more
2021eLife86 citations Open access
Semantic Scholar
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
Michelle M. McDonald, Weng-Hua Khoo, P. Ng, Ya Xiao +42 more
2021Cell72 citations Open access
Semantic Scholar
ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism
S. T. Boyle, V. Poltavets, Jasreen Kular, Natasha T. Pyne +14 more
2020Nature Cell Biology67 citations
Semantic Scholar
Single cell transcriptome atlas of mouse mammary epithelial cells across development
B. Pal, Yun-Shun Chen, M. Milevskiy, F. Vaillant +9 more
2021Breast Cancer Research61 citations Open access
Semantic Scholar
Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP
G. Guo, M. Papanicolaou, N. Demarais, Z. Wang +4 more
2021Nature Communications60 citations Open access
Semantic Scholar
Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity
Chen-Xu Yan, Tian-Shu Zeng, Kai-Lun Lee, Max Nobis +18 more
2021Nature Communications51 citations Open access
Semantic Scholar
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype.
F. Valdés-Mora, R. Salomon, B. Gloss, Andrew M K Law +18 more
2021Cell Reports51 citations Open access
Semantic Scholar
Multiphoton intravital microscopy of rodents
C. Scheele, D. Herrmann, Erika Yamashita, C. L. Celso +9 more
2022Nature Reviews Methods Primers44 citations Open access
Semantic Scholar
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status
K. Murphy, Daniel A. Reed, C. Vennin, James R. W. Conway +43 more
2021Science Advances44 citations Open access
Semantic Scholar
Compression-dependent microtubule reinforcement enables cells to navigate confined environments
Robert J. Ju, Alistair Falconer, Christanny Schmidt, M. E. Enriquez Martinez +11 more
2024Nature Cell Biology41 citations Open access
Semantic Scholar
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC
Ebru Boslem, Saskia Reibe, R. Carlessi, B. Smeuninx +19 more
2023Science Advances39 citations Open access
Semantic Scholar
Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance
K. Murphy, Cecilia R. Chambers, D. Herrmann, P. Timpson +1 more
2021Cancers38 citations Open access
Semantic Scholar
The cancer cell secretome drives cooperative manipulation of the tumour microenvironment to accelerate tumourigenesis
Shona Ritchie, Daniel A. Reed, Brooke A. Pereira, P. Timpson
2021Faculty Reviews35 citations Open access
Semantic Scholar
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response
Brooke A. Pereira, Shona Ritchie, Cecilia R. Chambers, Katie A. Gordon +60 more
2024Science Advances24 citations Open access
Semantic Scholar
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma
Jordan F. Hastings, Sharissa L. Latham, Alvin Kamili, Madeleine S. Wheatley +27 more
2023Science Advances24 citations Open access
Semantic Scholar
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Alessia Floerchinger, K. Murphy, Sharissa L. Latham, Sean C. Warren +33 more
2021Cell Reports23 citations Open access
Semantic Scholar
Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism
E. Filipe, Sipiththa Velayuthar, Ashleigh M. Philp, Max Nobis +49 more
2024Advancement of science21 citations Open access
Semantic Scholar
Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes
N. Meagher, Kylie L. Gorringe, M. Wakefield, Adelyn Bolithon +107 more
2022Clinical Cancer Research21 citations Open access
Semantic Scholar
BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis
Rebeca Uceda-Castro, Andreia S. Margarido, Ji-Ying Song, M. D. de Gooijer +12 more
2023Science Advances18 citations Open access
Semantic Scholar
Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy
K. Murphy, Jessie Zhu, Michael Trpceski, Brooke A. Pereira +2 more
2022Biochemical Society Transactions17 citations Open access
Semantic Scholar
A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma
Alvaro Gonzalez Rajal, K. Marzec, R. Mccloy, Max Nobis +11 more
2021eLife17 citations Open access
Semantic Scholar
Targeting the NPY/NPY1R signaling axis in mutant p53–dependent pancreatic cancer impairs metastasis
Cecilia R. Chambers, Supitchaya Watakul, Peter R. Schofield, Anna E. Howell +60 more
2025Science Advances15 citations Open access
Semantic Scholar
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions
Jaimy Jose, Monira Hoque, J. Engel, S. S. Beevi +13 more
2022Scientific Reports15 citations Open access
Semantic Scholar
ROR1 and ROR2 expression in pancreatic cancer
Dong-Li Liu, G. Sharbeen, P. Phillips, A. Johns +85 more
2021BMC Cancer14 citations Open access
Semantic Scholar
Interfacial Curvature in Confined Coculture Directs Stromal Cell Activity with Spatial Corralling of Pancreatic Cancer Cells.
Stephanie Nemec, Joey Lam, Jing-Xiao Zhong, C. Heu +6 more
2021Advances in Biology14 citations Open access
Semantic Scholar
Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth
Michael S. Samuel, Jose I. Lopez, E. McGhee, D. Croft +12 more
2024Cancer Cell10 citations Open access
Semantic Scholar
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
James R. W. Conway, Sean C. Warren, Young-Kyung Lee, Andrew T. McCulloch +34 more
2023Science Advances10 citations Open access
Semantic Scholar
Minimally invasive longitudinal intravital imaging of cellular dynamics in intact long bone
N. D. Bhattacharyya, Wunna Kyaw, Michelle M. McDonald, Rama Dhenni +10 more
2023Nature Protocols10 citations
Semantic Scholar
Pathway profiling of a novel SRC inhibitor, AZD0424, in combination with MEK inhibitors for cancer treatment
John C. Dawson, A. Munro, Kenneth Macleod, M. Muir +5 more
2021bioRxiv10 citations Open access
Semantic Scholar
Compression-dependent microtubule reinforcement comprises a mechanostat which enables cells to navigate confined environments
R. Ju, Alistair Falconer, K. Dean, R. Fiolka +9 more
2022bioRxiv9 citations Open access
Semantic Scholar
Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse
Max Nobis, D. Herrmann, Sean C. Warren, D. Strathdee +3 more
2020Small GTPases9 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Unmasking senescence: context-dependent effects of SASP in cancer.
P. Timpson
2020Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature9 citations
Semantic Scholar
ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion.
N. Sue, Le May Thai, Ebru Boslem, Kwan Y. Chu +13 more
2025Cell Reports8 citations Open access
Semantic Scholar
Quantifying and visualising the nuances of cellular dynamics in vivo using intravital imaging.
K. Murphy, Daniel A. Reed, Michael Trpceski, D. Herrmann +1 more
2021Current Opinion in Cell Biology8 citations
Semantic Scholar
Fibroblast Growth Factor-induced lens fiber cell elongation is driven by the stepwise activity of Rho and Rac
Yuki Sugiyama, Daniel A. Reed, D. Herrmann, F. J. Lovicu +3 more
2023bioRxiv6 citations Open access
Semantic Scholar
Bystander Expression of Atypical Chemokine Receptor 2 Protects T Cells from Chemoattraction towards Cancer‐Associated Fibroblasts
R. Tang, Szun S. Tay, G. Sharbeen, David Herrmann +4 more
2025European Journal of Immunology4 citations Open access
Semantic Scholar
The effect of adding a selective FAK inhibitor AMP945 to FOLFIRINOX in a model of pancreatic cancer.
C. Burns, K. Murphy, Terrie-Anne Cock, M. Devlin +2 more
2023Journal of Clinical Oncology4 citations
Semantic Scholar
Cell-derived Matrix Assays to Assess Extracellular Matrix Architecture and Track Cell Movement.
K. Murphy, Daniel A. Reed, Cecilia R. Chambers, Jessie Zhu +4 more
2022Bio-protocol4 citations Open access
Semantic Scholar
Targeting genetically-tuned CAFs in pancreatic cancer via perlecan manipulation
Shona Ritchie, Brooke A. Pereira, C. Vennin, P. Timpson
2020Expert opinion on therapeutic targets3 citations
Semantic Scholar
Correction for Morton et al., Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
J. Morton, P. Timpson, S. Karim, Rachel +7 more
2022Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer
Y. Chey, Bassam Kashgari, L. McLeod, Georgette Radford +16 more
2026Nature Communications1 citations Open access
Semantic Scholar
Using rotational integration of oblique interferometric scattering (RO-iSCAT) to track axial spatiotemporal responses of membrane protrusions
Jun-Yu Liu, Y. Lim, David Herrmann, P. Timpson +4 more
2025bioRxiv1 citations Open access
Semantic Scholar

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Cecilia R. Chambers

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