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C. Desler · SciRah

Researcher profile · Semantic Scholar

C. Desler

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C. Desler — researcher profile on SciRah

h-index: 21
Works: 57
Citations: 1,572

Most-cited papers

Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
C. Desler, Thomas Lau Hansen, J. B. Frederiksen, Maiken Lise Marcker +2 more
2012Journal of Aging Research236 citations Open access
Semantic Scholar
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
José Fernández Navarro, D. Croteau, A. Jurek, Žaneta Andrusivová +11 more
2020iScience95 citations Open access
Semantic Scholar
Enterococcus faecalis Infection Causes Inflammation, Intracellular Oxphos-Independent ROS Production, and DNA Damage in Human Gastric Cancer Cells
Jesper A. B. Strickertsson, C. Desler, Tomas Martin-Bertelsen, Ana Manuel Dantas Machado +4 more
2013PLoS ONE92 citations Open access
Semantic Scholar
Mitochondria as determinant of nucleotide pools and chromosomal stability.
C. Desler, B. Munch‐Petersen, T. Stevnsner, S. Matsui +3 more
2007Mutation research84 citations
Semantic Scholar
Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages.
K. Jantzen, M. Roursgaard, C. Desler, S. Loft +2 more
2012Mutagenesis81 citations
Semantic Scholar
The Effect of Mitochondrial Dysfunction on Cytosolic Nucleotide Metabolism
C. Desler, A. Lykke, L. Rasmussen
2010Journal of Nucleic Acids63 citations Open access
Semantic Scholar
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
A. López-Contreras, Julia Specks, J. Barlow, C. Ambrogio +8 more
2015Genes & Development62 citations Open access
Semantic Scholar
The Importance of Mitochondrial DNA in Aging and Cancer
C. Desler, Maiken Lise Marcker, Keshav K. Singh, L. Rasmussen
2011Journal of Aging Research57 citations Open access
Semantic Scholar
The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease
C. Desler, Meryl S. Lillenes, T. Tønjum, L. Rasmussen
2017Current Medicinal Chemistry56 citations Open access
Semantic Scholar
MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells
Marlies J. W. Peeters, Donata Dulkeviciute, A. Draghi, Cathrin Ritter +15 more
2019Cancer immunology research51 citations Open access
Semantic Scholar
Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients
S. Maynard, A. Hejl, T. T. Dinh, G. Keijzers +7 more
2015Aging50 citations Open access
Semantic Scholar
Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells.
Ana Manuel Dantas Machado, C. Desler, Sisse Bøggild, Jesper A. B. Strickertsson +4 more
2013Mechanisms of Ageing and Development50 citations
Semantic Scholar
Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
S. Maynard, G. Keijzers, Martin Gram, C. Desler +10 more
2013Aging49 citations Open access
Semantic Scholar
Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair
M. Akbari, G. Keijzers, S. Maynard, M. Scheibye-Knudsen +3 more
2014DNA Repair44 citations Open access
Semantic Scholar
Oxidative Stress-Induced Dysfunction of Müller Cells During Starvation.
A. K. Toft-Kehler, Iswariaraja Scridevi Gurubaran, C. Desler, L. Rasmussen +2 more
2016Investigative Ophthalmology and Visual Science42 citations Open access
Semantic Scholar
In Silico screening for functional candidates amongst hypothetical proteins
C. Desler, Prashanth N. Suravajhala, May Sanderhoff, Merete Rasmussen +1 more
2009BMC Bioinformatics39 citations Open access
Semantic Scholar
Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
Marlies J. W. Peeters, Pia Aehnlich, A. Pizzella, Kasper Mølgaard +5 more
2021Frontiers in Immunology31 citations Open access
Semantic Scholar
The inhibitors of soluble adenylate cyclase 2‐OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms
Emil Jakobsen, S. C. Lange, J. V. Andersen, C. Desler +6 more
2018Biochemical Pharmacology24 citations
Semantic Scholar
Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1.
R. Vohra, I. S. Gurubaran, U. Henriksen, L. Bergersen +4 more
2017Mitochondrion (Amsterdam. Print)24 citations Open access
Semantic Scholar
A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
S. Syed, C. Desler, L. Rasmussen, K. Schmidt
2016PLoS Genetics23 citations Open access
Semantic Scholar
Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
V. Subramanian, B. Rodemoyer, Vivek M. Shastri, L. Rasmussen +2 more
2021Scientific Reports22 citations Open access
Semantic Scholar
Simvastatin improves mitochondrial respiration in peripheral blood cells
J. A. Durhuus, Svenja Hansson, Thomas Morville, Anja C. B. Kuhlman +10 more
2020Scientific Reports19 citations Open access
Semantic Scholar
From Powerhouse to Perpetrator—Mitochondria in Health and Disease
Nima B Fakouri, Thomas Lau Hansen, C. Desler, Sharath Anugula +1 more
2019Biology19 citations Open access
Semantic Scholar
Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis
Nima B Fakouri, J. A. Durhuus, C. Regnell, Maria Angleys +10 more
2017Scientific Reports19 citations Open access
Semantic Scholar
Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage
B. M. Hopkinson, C. Desler, M. Kalisz, P. S. Vestentoft +2 more
2017Oxidative Medicine and Cellular Longevity19 citations Open access
Semantic Scholar
Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus.
K. Thomsen, T. Yokota, M. Hasan-Olive, Niloofar Sherazi +8 more
2018Neurobiology of Aging17 citations
Semantic Scholar
Bacterial infection increases risk of carcinogenesis by targeting mitochondria.
Jesper A. B. Strickertsson, C. Desler, L. Rasmussen
2017Seminars in Cancer Biology16 citations Open access
Semantic Scholar
Mitochondria in biology and medicine--2012.
C. Desler, L. Rasmussen
2014Mitochondrion (Amsterdam. Print)16 citations
Semantic Scholar
Genome-wide screens for expressed hypothetical proteins.
C. Desler, J. A. Durhuus, L. Rasmussen
2012Methods in molecular biology16 citations
Semantic Scholar
Repair of DNA damage induced by anthanthrene, a polycyclic aromatic hydrocarbon (PAH) without bay or fjord regions.
C. Desler, Christian Johannessen, L. Rasmussen
2009Chemico-Biological Interactions16 citations
Semantic Scholar
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells
S. H. Møller, Maiken Mellergaard, M. Madsen, A. V. Bermejo +16 more
2020Frontiers in Immunology15 citations Open access
Semantic Scholar
Human fibroblasts from sporadic Alzheimer's disease (AD) show mitochondrial alterations and lysosome dysfunction.
Yuan Li, Zhiquan Li, Emanuela Grillo, C. Desler +4 more
2024Free Radical Biology & Medicine14 citations Open access
Semantic Scholar
Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected
L. Christiansen, T. Dohlmann, T. P. Ludvigsen, Ewa Parfieniuk +9 more
2021Scientific Reports13 citations Open access
Semantic Scholar
Impact of bacterial infections on aging and cancer: impairment of DNA repair and mitochondrial function of host cells.
Jesper A. B. Strickertsson, C. Desler, L. Rasmussen
2014Experimental Gerontology13 citations
Semantic Scholar
Mitochondria in biology and medicine.
C. Desler, L. Rasmussen
2012Mitochondrion (Amsterdam. Print)13 citations
Semantic Scholar
Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions
V. A. Bjerregaard, Bitten Schönewolf-Greulich, Lene Juel Rasmussen, C. Desler +1 more
2020Frontiers in Neurology11 citations Open access
Semantic Scholar
The Role of Mitochondrial dNTP Levels in Cells with Reduced TK2 Activity
C. Desler, Birgitte Munch-Petersen, L. J. Rasmussen
2006Nucleosides, Nucleotides & Nucleic Acids11 citations
Semantic Scholar
Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
C. Desler, J. H. Frederiksen, Maria Angleys, S. Maynard +7 more
2015Mitochondrion (Amsterdam. Print)10 citations Open access
Semantic Scholar
Mitochondrial oxidative phosphorylation capacity of cryopreserved cells.
Poul Ejner Lauridsen, L. Rasmussen, C. Desler
2019Mitochondrion (Amsterdam. Print)8 citations
Semantic Scholar
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation.
C. Desler, Jon Ambæk Durhuus, Thomas Lau Hansen, Sharath Anugula +3 more
2022Mitochondrion (Amsterdam. Print)7 citations Open access
Semantic Scholar
Mitochondria in health and disease - 3rd annual conference of society for mitochondrial research and medicine - 19-20 December 2013 - Bengaluru, India.
J. A. Durhuus, C. Desler, L. Rasmussen
2015Mitochondrion (Amsterdam. Print)7 citations
Semantic Scholar
Author Correction: Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis
Nima B Fakouri, J. A. Durhuus, C. Regnell, Maria Angleys +10 more
2018Scientific Reports5 citations Open access
Semantic Scholar
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Nima B Fakouri, J. A. Durhuus, C. Regnell, Maria Angleys +11 more
20174 citations
Semantic Scholar
Analysis of the antimicrobial susceptibility of the ionizing radiation-resistant bacterium Deinococcus radiodurans: implications for bioremediation of radioactive waste
H. Sghaier, O. Bouchami, C. Desler, Hadeer Lazim +3 more
2011Annals of Microbiology4 citations Open access
Semantic Scholar
Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Sharath Anugula, Zhiquan Li, Yuan Li, Alexander Hendriksen +8 more
2023Heliyon3 citations Open access
Semantic Scholar
Introducing the hypothome: a way to integrate predicted proteins in interactomes
C. Desler, Sine Zambach, Prashanth N. Suravajhala, L. Rasmussen
2014International Journal of Bioinformatics Research and Applications3 citations
Semantic Scholar
Mitochondrial-linked de novo pyrimidine synthesis as a regulator of T cell responses
Marlies J. W. Peeters, C. Desler, P. Thor Straten
2023Immunometabolism2 citations Open access
Semantic Scholar
Real-time Monitoring of Mitochondrial Respiration in Cytokine-differentiated Human Primary T Cells.
Kasper Mølgaard, Anne Rahbech, Ö. Met, I. Svane +3 more
2021Journal of Visualized Experiments2 citations Open access
Semantic Scholar
Involvement of Mitochondrial Dysfunction in FOXG1 Syndrome
V. A. Bjerregaard, Amanda M. Levy, Mille S. Batz, Ravina Salehi +5 more
2023Genes0 citations Open access
Semantic Scholar
Effects of modified nucleosides on β-cell function – a contribution to islet dysfunction in Type 2 diabetes?
Inga Šileikaitė, M. Davies, C. Desler, T. Mandrup-Poulsen +1 more
2023Free Radical Biology & Medicine0 citations Open access
Semantic Scholar

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