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I. Svane · SciRah

Researcher profile · Semantic Scholar

I. Svane

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I. Svane — researcher profile on SciRah

h-index: 65
Works: 455
Citations: 17K

Most-cited papers

Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma.
M. Rohaan, T. H. Borch, J. H. van den Berg, Ö. Met +53 more
2022New England Journal of Medicine452 citations Open access
Semantic Scholar
Clinical advances and ongoing trials of mRNA vaccines for cancer treatment
C. Lorentzen, J. Haanen, Ö. Met, I. Svane
2022The Lancet Oncology369 citations Open access
Semantic Scholar
Author Correction: A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
J. Kjeldsen, C. Lorentzen, E. Martinenaite, E. Ellebaek +13 more
2022Nature Medicine161 citations Open access
Semantic Scholar
Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
G. Dolton, C. Rius, A. Wall, Barbara Szomolay +29 more
2023Cell138 citations Open access
Semantic Scholar
Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)
I. Chen, J. Johansen, S. Theile, J. Hjaltelin +14 more
2022Journal of Clinical Oncology92 citations Open access
Semantic Scholar
Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming
Olga Zimmermannova, A. G. Ferreira, Ervin Ascic, M. Santiago +25 more
2023Science immunology82 citations Open access
Semantic Scholar
Molecular patterns of resistance to immune checkpoint blockade in melanoma
M. Lauss, B. Phung, T. H. Borch, K. Harbst +12 more
2024Nature Communications79 citations Open access
Semantic Scholar
TIL Therapy: Facts and Hopes.
T. Monberg, T. H. Borch, I. Svane, M. Donia
2023Clinical Cancer Research76 citations Open access
Semantic Scholar
Stage-Specific Risk of Recurrence and Death From Melanoma in Denmark, 2008-2021: A National Observational Cohort Study of 25 720 Patients With Stage IA to IV Melanoma.
N. M. Helvind, Marie Brinch-Møller Weitemeyer, A. Chakera, H. Hendel +10 more
2023JAMA dermatology75 citations Open access
Semantic Scholar
Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy
C. Chamberlain, Eric Paul Bennett, A. Kverneland, I. Svane +2 more
2022Molecular Therapy: Oncolytics68 citations Open access
Semantic Scholar
Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions
J. Granhøj, Agnete Witness Præst Jensen, M. Presti, Ö. Met +2 more
2022Expert Opinion on Biological Therapy64 citations
Semantic Scholar
Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma
Sofie Kirial Mørk, M. Kadivar, K. Bol, A. Draghi +16 more
2022Oncoimmunology59 citations Open access
Semantic Scholar
Fully Automated Workflow for Integrated Sample Digestion and Evotip Loading Enabling High-Throughput Clinical Proteomics
A. Kverneland, Florian S. Harking, J. Vej-Nielsen, Magnus Huusfeldt +4 more
2023bioRxiv48 citations Open access
Semantic Scholar
Arginase-1 targeting peptide vaccine in patients with metastatic solid tumors – A phase I trial
C. Lorentzen, E. Martinenaite, J. Kjeldsen, R. Holmstroem +5 more
2022Frontiers in Immunology41 citations Open access
Semantic Scholar
Phase 2 study of ipilimumab, nivolumab, and tocilizumab combined with stereotactic body radiotherapy in patients with refractory pancreatic cancer (TRIPLE-R).
I. Chen, M. Donia, C. Chamberlain, A. W. P. Jensen +12 more
2022European Journal of Cancer39 citations Open access
Semantic Scholar
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
A. Kverneland, Ole Østergaard, K. B. Emdal, I. Svane +1 more
2022Proteomics38 citations Open access
Semantic Scholar
PD-L1 is a biomarker of real-world clinical outcomes for anti-CTLA-4 plus anti-PD-1 or anti-PD-1 monotherapy in metastatic melanoma.
E. Ellebaek, Shawez Khan, L. Bastholt, Henrik Schmidt +3 more
2023European Journal of Cancer32 citations Open access
Semantic Scholar
Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types
N. Willumsen, C. Jensen, G. Green, N. Nissen +21 more
2022Cellular and Molecular Life Sciences32 citations Open access
Semantic Scholar
Tofacitinib and faecal microbiota transplantation in treating checkpoint inhibitor-induced enterocolitis: case report
R. Holmstroem, E. Dahl, M. Helms, H. Nielsen +5 more
2022BMJ Open Gastroenterology26 citations Open access
Semantic Scholar
Safety and efficacy of infliximab and corticosteroid therapy in checkpoint inhibitor‐induced colitis
E. Dahl, O. Abed, J. Kjeldsen, M. Donia +5 more
2022Alimentary Pharmacology and Therapeutics26 citations Open access
Semantic Scholar
IMPROVE: a feature model to predict neoepitope immunogenicity through broad-scale validation of T-cell recognition
A. Borch, Ibel Carri, Birkir Reynisson, Heli M. Garcia Alvarez +19 more
2024Frontiers in Immunology25 citations Open access
Semantic Scholar
Improving shared decision-making about cancer treatment through design-based data-driven decision-support tools and redesigning care paths: an overview of the 4D PICTURE project
J. Rietjens, I. Griffioen, J. Sierra-Pérez, G. Sroczynski +64 more
2024Palliative Care and Social Practice25 citations Open access
Semantic Scholar
The antitumor activity of TGFβ-specific T cells is dependent on IL-6 signaling
M. Perez-Penco, M. Byrdal, L. Lara de la Torre, Marta Ballester +15 more
2024Cellular & Molecular Immunology23 citations Open access
Semantic Scholar
Survival improvements in patients with melanoma brain metastases and leptomeningeal disease in the modern era: Insights from a nationwide study (2015-2022).
S. Pedersen, E. L. Johansen, K. Højholt, Maria Pedersen +9 more
2025European Journal of Cancer21 citations Open access
Semantic Scholar
State-Of-The-Art Advancements on Cancer Vaccines and Biomarkers.
S. Strum, M. Andersen, I. Svane, L. Siu +1 more
2024American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting21 citations
Semantic Scholar
Quality of life and mental health in real-world patients with resected stage III/IV melanoma receiving adjuvant immunotherapy
S. Pedersen, R. Holmstroem, Annika von Heymann, L. Tolstrup +8 more
2023Acta oncologica18 citations Open access
Semantic Scholar
Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune response on drug exposure
A. Spreafico, E. M. Couselo, A. Irmisch, J. Bessa +19 more
2024Frontiers in Oncology17 citations Open access
Semantic Scholar
An arginase1- and PD-L1-derived peptide-based vaccine for myeloproliferative neoplasms: A first-in-man clinical trial
J. Grauslund, M. Holmström, E. Martinenaite, T. Lisle +10 more
2023Frontiers in Immunology16 citations Open access
Semantic Scholar
Immune-related adverse events in a nationwide cohort of real-world melanoma patients treated with adjuvant anti-PD1 - Seasonal variation and association with outcome.
R. Jurlander, L. M. Guldbrandt, R. Holmstroem, K. Madsen +7 more
2024European Journal of Cancer15 citations Open access
Semantic Scholar
LBA3 Treatment with tumor-infiltrating lymphocytes (TIL) versus ipilimumab for advanced melanoma: Results from a multicenter, randomized phase III trial
J. Haanen, M. Rohaan, T. H. Borch, J. H. van den Berg +16 more
2022Annals of Oncology15 citations Open access
Semantic Scholar
Clinical value of routine [18F]2‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography scans as a decision tool for early immunotherapy discontinuation in advanced melanoma
E. Ellebaek, A. Schina, R. Andersen, H. Hendel +2 more
2022International Journal of Cancer14 citations Open access
Semantic Scholar
Uncoupling CD4+ TIL-mediated tumor killing from JAK-signaling in melanoma.
A. Draghi, M. Presti, A. W. P. Jensen, C. Chamberlain +6 more
2023Clinical Cancer Research13 citations Open access
Semantic Scholar
Feasibility of Intratumoral Anti-PD1 as Treatment of Human Basal Cell Carcinoma: An Explorative Study with Adjuvant Ablative Fractional Laser
S. Omland, Jacob S. Ejlertsen, D. Krustrup, R. L. Christensen +3 more
2022Cancers13 citations Open access
Semantic Scholar
Outcome of adjuvant immunotherapy in a real-world nation-wide cohort of patients with melanoma.
R. Holmstroem, S. Pedersen, R. Jurlander, K. Madsen +7 more
2024European Journal of Cancer12 citations Open access
Semantic Scholar
Nivolumab Reaches Brain Lesions in Patients with Recurrent Glioblastoma and Induces T-cell Activity and Upregulation of Checkpoint Pathways
S. Skadborg, S. Maarup, A. Draghi, A. Borch +13 more
2024Cancer immunology research11 citations Open access
Semantic Scholar
Peptide vaccination activating Galectin-3-specific T cells offers a novel means to target Galectin-3-expressing cells in the tumor microenvironment
S. K. Bendtsen, M. Perez-Penco, M. L. Hübbe, E. Martinenaite +15 more
2022Oncoimmunology11 citations Open access
Semantic Scholar
Real-world data on melanoma brain metastases and survival outcome
S. Pedersen, Søren Møller, M. Donia, G. Persson +2 more
2022Melanoma research10 citations
Semantic Scholar
Co-existing alterations of MHC class I antigen presentation and IFNγ signaling mediate acquired resistance of melanoma to post-PD-1 immunotherapy.
M. Nielsen, M. Presti, Z. Sztupinszki, A. W. P. Jensen +9 more
2022Cancer immunology research10 citations Open access
Semantic Scholar
First in man study: Bcl-Xl_42-CAF®09b vaccines in patients with locally advanced prostate cancer
Sofie Kirial Mørk, P. Kongsted, M. Westergaard, B. Albieri +18 more
2023Frontiers in Immunology9 citations Open access
Semantic Scholar
Neoadjuvant or perioperative immunotherapy for resectable melanoma: The need for biomarkers.
E. Ellebaek, M. Donia, I. Svane
2025European Journal of Cancer8 citations Open access
Semantic Scholar
Nivolumab With or Without Ipilimumab Combined with Stereotactic Body Radiotherapy in patients with Metastatic Biliary Tract Cancer: A Randomized Phase 2 Study.
A. Markussen, J. S. Johansen, F. Larsen, S. Theile +12 more
2024Clinical Cancer Research7 citations
Semantic Scholar
Real-World Cardiotoxicity in Metastatic Melanoma Patients Treated with Encorafenib and Binimetinib
S. Pedersen, M. Nielsen, M. Donia, I. Svane +2 more
2024Cancers7 citations Open access
Semantic Scholar
Earlier Recurrence Detection Using Routine FDG PET-CT Scans in Surveillance of Stage IIB to IIID Melanoma: A National Cohort Study of 1480 Patients
N. M. Helvind, Marie B. Weitemeyer, A. Chakera, H. Hendel +10 more
2023Annals of Surgical Oncology7 citations Open access
Semantic Scholar
EMRseq: Registry-based outcome analysis on 1,000 patients with BRAF V600–mutated metastatic melanoma in Europe treated with either immune checkpoint or BRAF-/MEK inhibition.
M. Weichenthal, I. Svane, Lidija Kandolf Sekulovič, J. Mangana +16 more
2022Journal of Clinical Oncology7 citations
Semantic Scholar
Impact of Metastatic Pattern on Survival in Patients with Posterior Uveal Melanoma: A Retrospective Cohort Study
T. G. Hindso, Peter S Jensen, M. B. Sjøl, Kristoffer Nissen +10 more
2024Cancers6 citations Open access
Semantic Scholar
Efficacy of Ipilimumab and Nivolumab in Patients with Melanoma and Brain Metastases—A Danish Real-World Cohort
Karoline Dreyer Kattenhøj, Christine Louise Møberg, L. M. Guldbrandt, R. Friis +7 more
2024Cancers6 citations Open access
Semantic Scholar
Pembrolizumab (pembro) plus dabrafenib (dab) and trametinib (tram) in BRAFV600E/K-mutant melanoma: Long-term follow-up of KEYNOTE-022 parts 1, 2, and 3.
A. Ribas, P. Ferrucci, V. Atkinson, R. Stephens +15 more
2022Journal of Clinical Oncology6 citations
Semantic Scholar
LTX-315 and adoptive cell therapy using tumor-infiltrating lymphocytes in patients with metastatic soft tissue sarcoma.
M. Nielsen, T. Monberg, B. Albieri, V. Sundvold +3 more
2022Journal of Clinical Oncology5 citations
Semantic Scholar
Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV
U. Klausen, J. Grauslund, N. Jørgensen, S. Ahmad +14 more
2022Frontiers in Oncology5 citations Open access
Semantic Scholar
8P Phenotypic characterization of infused tumor-infiltrating lymphocytes (TIL) correlates with response to adoptive cellular therapy (ACT) in patients with metastatic melanoma (MM)
J. Granhøj, M. Rohaan, T. H. Borch, M. Presti +11 more
2022Immuno-Oncology and Technology5 citations Open access
Semantic Scholar

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M. Donia×28
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M. Donia — researcher profile on SciRah
E. Ellebaek×15
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E. Ellebaek — researcher profile on SciRah
Ö. Met×8
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Ö. Met — researcher profile on SciRah
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