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A. Rufer · SciRah

Researcher profile · Semantic Scholar

A. Rufer

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A. Rufer — researcher profile on SciRah

h-index: 23
Works: 56
Citations: 2,157

Most-cited papers

Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose
C. Ferrara, Sandra Grau, C. Jäger, P. Sondermann +8 more
2011Proceedings of the National Academy of Sciences of the United States of America790 citations Open access
Semantic Scholar
A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor- (cid:1) (PPAR (cid:1) ) Recruits PPAR (cid:1) -Coactivator-1 (cid:2) , Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro
E. Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
2006128 citations
Semantic Scholar
Structural Properties of AMP-activated Protein Kinase
Uwe Riek, R. Scholz, P. Konarev, A. Rufer +13 more
2008Journal of Biological Chemistry95 citations Open access
Semantic Scholar
A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation
Hua-Ying Zhao, R. Ghirlando, Carlos Alfonso, F. Arisaka +116 more
2015PLoS ONE91 citations Open access
Semantic Scholar
Structural insight into function and regulation of carnitine palmitoyltransferase
A. Rufer, R. Thoma, M. Hennig
2009Cellular and Molecular Life Sciences86 citations Open access
Semantic Scholar
The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment.
A. Rufer, R. Thoma, J. Benz, M. Stihle +6 more
2006Structure71 citations Open access
Semantic Scholar
Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.
N. Bocquet, Josiane Kohler, M. Hug, E. Kusznir +6 more
2015Biochimica et Biophysica Acta68 citations Open access
Semantic Scholar
Structure and Function of Purified Monoclonal Antibody Dimers Induced by Different Stress Conditions
R. Paul, A. Graff-Meyer, H. Stahlberg, Matthias E. Lauer +6 more
2012Pharmaceutical Research64 citations Open access
Semantic Scholar
Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody
P. Favuzza, Elena Guffart, M. Tamborrini, Bianca Scherer +13 more
2017eLife62 citations Open access
Semantic Scholar
A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.
E. Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
2006Molecular Endocrinology57 citations
Semantic Scholar
Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury
Maia Tato, Santhosh V Kumar, Ya-Juan Liu, S. R. Mulay +9 more
2017Scientific Reports55 citations Open access
Semantic Scholar
Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs
Friederike Plath, P. Ringler, A. Graff-Meyer, H. Stahlberg +9 more
2016mAbs50 citations Open access
Semantic Scholar
Drug discovery for enzymes.
A. Rufer
2021Drug Discovery Today46 citations Open access
Semantic Scholar
Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain
D. Schlatter, Simon S. Brack, D. Banner, S. Batey +9 more
2012mAbs45 citations Open access
Semantic Scholar
Dimerization-induced activation of soluble insulin/IGF-1 receptor kinases: an alternative mechanism of activation.
Kristin E. Baer, H. Al-Hasani, Susan Parvaresch, Teresa Corona +4 more
2001Biochemistry38 citations
Semantic Scholar
Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP.
Matthias E. Lauer, A. Graff-Meyer, A. Rufer, C. Maugeais +12 more
2016Journal of Structural Biology37 citations Open access
Semantic Scholar
Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct
Alexandra Gehrlein, Vinod Udayar, Nadia Anastasi, Martino L. Morella +22 more
2023Nature Communications36 citations Open access
Semantic Scholar
Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein
S. Perspicace, A. Rufer, R. Thoma, Francis Mueller +4 more
2013FEBS Open Bio31 citations Open access
Semantic Scholar
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
Roman C. Sarott, Matthias V. Westphal, P. Pfaff, C. Korn +53 more
2020Journal of the American Chemical Society30 citations Open access
Semantic Scholar
Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport
N. Ruderisch, D. Schlatter, A. Kuglstatter, W. Guba +15 more
2017EBioMedicine26 citations Open access
Semantic Scholar
Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.
D. Banner, B. Gsell, J. Benz, J. Bertschinger +21 more
2013Acta Crystallographica Section D: Biological Crystallography26 citations Open access
Semantic Scholar
A Novel Selective Inverse Agonist of the CB2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies
A. Martella, Huub J Sijben, A. Rufer, U. Grether +6 more
2017Molecular Pharmacology25 citations Open access
Semantic Scholar
A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro
Elke Burgermeister, A. Schnoebelen, A. Flament, J. Benz +10 more
200624 citations Open access
Semantic Scholar
Isoform-selective interaction of the adaptor protein Tks5/FISH with Sos1 and dynamins.
A. Rufer, J. Rumpf, Max von Holleben, S. Beer +2 more
2009Journal of Molecular Biology23 citations
Semantic Scholar
Carnitine palmitoyltransferase 2: Analysis of membrane association and complex structure with a substrate analog
A. Rufer, A. Lomize, J. Benz, Odile Chomienne +2 more
2007FEBS Letters23 citations Open access
Semantic Scholar
Novel β-Glucocerebrosidase activators that bind to a new pocket at a dimer interface and induce dimerization.
J. Benz, A. Rufer, S. Huber, A. Ehler +6 more
2020Angewandte Chemie21 citations
Semantic Scholar
Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies*
D. Burger, M. Stihle, Ashwani Sharma, P. Di Lello +16 more
2016Journal of Biological Chemistry19 citations Open access
Semantic Scholar
X-ray structure of glutathione S-transferase from Schistosoma japonicum in a new crystal form reveals flexibility of the substrate-binding site.
A. Rufer, Lars Thiebach, Kristin E. Baer, H. Klein +1 more
2005Acta Crystallographica. Section F : Structural Biology and Crystallization Communications18 citations Open access
Semantic Scholar
Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe
Thais Gazzi, Benjamin Brennecke, Kenneth Atz, C. Korn +53 more
2022Chemical Science17 citations Open access
Semantic Scholar
Generation, Characterization, and Quantitative Bioanalysis of Drug/Anti-drug Antibody Immune Complexes to Facilitate Dedicated In Vivo Studies
Eugenia Hoffmann, Gregor Jordan, Matthias E. Lauer, P. Ringler +6 more
2019Pharmaceutical Research17 citations Open access
Semantic Scholar
Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain
Kirsten Richter, A. Rufer, Magali Muller, D. Burger +9 more
2020Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Domain swap in the C-terminal ubiquitin-like domain of human doublecortin.
A. Rufer, E. Kusznir, D. Burger, M. Stihle +2 more
2018Acta Crystallographica Section D: Structural Biology10 citations Open access
Semantic Scholar
Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors
Morgan Scott-Dennis, F. A. Rafani, Yi-Chen Yi, Themiya P Perera +6 more
2023Frontiers in Pharmacology8 citations Open access
Semantic Scholar
Diverse chemotypes drive biased signaling by cannabinoid receptors
Tamara Miljuš, Franziska M. Heydenreich, Thais Gazzi, Atsushi Kimbara +13 more
2020bioRxiv5 citations Open access
Semantic Scholar
Advances in Chemical Probing Concepts for Chemical Biology Applications
P. Arimondo, S. Essig, U. Schopfer, A. Rufer
2023ChemBioChem1 citations Open access
Semantic Scholar
Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1
Kirsten Richter, A. Rufer, Magali Muller, D. Burger +9 more
2020Journal of Biological Chemistry1 citations Open access
Semantic Scholar
Biophysical Assessment of Target Protein Quality in Structure‐Based Drug Discovery
A. Rufer, M. Hennig
20201 citations
Semantic Scholar
Drug Derived Fluorescent Probes for the Specific Visualization of Cannabinoid Type 2 Receptor - A Toolbox Approach
Thais Gazzi, Benjamin Brennecke, Kenneth Atz, C. Korn +46 more
20191 citations Open access
Semantic Scholar
CRYSTAL STRUCTURE OF GLUCOCEREBROSIDASE IN COMPLEX WITH A PYRROLOPYRAZINE
J. Benz, A. Ehler, M. Hug, S. Huber +5 more
20200 citations
Semantic Scholar
Highly Specific, Fluorescent Cannabinoid Type 2 Receptor Probes Enable Applications in Microscopy, Flow Cytometry and FRET-based Binding Assays
Roman C. Sarott, Matthias V. Westphal, P. Pfaff, C. Korn +50 more
20190 citations Open access
Semantic Scholar
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
A. Ruf, J. Benz, D. Burger, B. D'Arcy +16 more
20160 citations
Semantic Scholar
Structural and Functional Characterization of Doublecortin Domains 1 Crystal Structures of the Human Doublecortin Cand N-terminal Domains in Complex with Specific Antibodies
D. Burger, M. Stihle, Ashwani Sharma, P. Di Lello +16 more
20160 citations
Semantic Scholar
Author response: Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody
P. Favuzza, Elena Guffart, M. Tamborrini, Bianca Scherer +13 more
20160 citations Open access
Semantic Scholar
Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone
M. Rudolph, J. Benz, D. Burger, R. Thoma +2 more
20130 citations
Semantic Scholar
CRYSTAL STRUCTURE OF RAT CARNITINE PALMITOYLTRANSFERASE 2 IN COMPLEX WITH CoA-site inhibitor
A. Rufer, R. Thoma, J. Benz, M. Stihle +6 more
20130 citations
Semantic Scholar
TERNARY BACE2 XAPERONE COMPLEX
A. Kuglstatter, D. Banner, J. Benz, J. Bertschinger +18 more
20130 citations
Semantic Scholar
Fyn, Fab, Xap: evaluation of different protein binders as crystallization aids
A. Ruf, D. Banner, J. Benz, J. Bertschinger +18 more
20120 citations Open access
Semantic Scholar
Human Chymase - Fynomer Complex
D. Schlatter, Simon S. Brack, D. Banner, S. Batey +9 more
20120 citations
Semantic Scholar
Structure and Function of Purified Monoclonal Antibody Dimers Induced by Different Stress Conditions
R. Paul, A. Graff-Meyer, H. Stahlberg, Matthias E. Lauer +6 more
2012Pharmaceutical Research0 citations Open access
Semantic Scholar
Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212
A. Rufer, R. Thoma, J. Benz, M. Stihle +6 more
20070 citations
Semantic Scholar

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