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J. Guinney · SciRah

Researcher profile · Semantic Scholar

J. Guinney

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J. Guinney — researcher profile on SciRah

h-index: 47
Works: 190
Citations: 36K

Most-cited papers

The Immune Landscape of Cancer
V. Thorsson, D. Gibbs, S. Brown, D. Wolf +496 more
2018Immunity4,928 citations Open access
Semantic Scholar
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution
O. Rozenblatt-Rosen, A. Regev, Philipp Oberdoerffer, T. Nawy +362 more
2020Cell514 citations Open access
Semantic Scholar
The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment
M. Haendel, C. Chute, T. Bennett, David A. Eichmann +52 more
2020J. Am. Medical Informatics Assoc.495 citations Open access
Semantic Scholar
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
Daniel K. Wells, M. Buuren, Kristen K. Dang, Vanessa M. Hubbard-Lucey +141 more
2020Cell495 citations Open access
Semantic Scholar
Evaluation of Combined Artificial Intelligence and Radiologist Assessment to Interpret Screening Mammograms
T. Schaffter, D. Buist, Christoph I. Lee, Yaroslav Nikulin +69 more
2020JAMA Network Open356 citations Open access
Semantic Scholar
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
M. Menden, Dennis Wang, M. Mason, B. Szalai +350 more
2019Nature Communications321 citations Open access
Semantic Scholar
The Immune Landscape of Cancer.
V. Thorsson, D. Gibbs, S. Brown, D. Wolf +53 more
2019Immunity287 citations Open access
Semantic Scholar
Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative
T. Bennett, R. Moffitt, J. Hajagos, Benjamin R. C. Amor +41 more
2021JAMA Network Open232 citations Open access
Semantic Scholar
Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer
R. Dienstmann, G. Villacampa, A. Sveen, M. Mason +6 more
2019Annals of Oncology185 citations Open access
Semantic Scholar
A Multifaceted benchmarking of synthetic electronic health record generation models
Chao Yan, Yao Yan, Zhi-Yu Wan, Ziqi Zhang +4 more
2022Nature Communications135 citations Open access
Semantic Scholar
Machine learning in rare disease
Jineta Banerjee, Jaclyn N. Taroni, Robert J. Allaway, D. V. Prasad +2 more
2023Nature Methods122 citations Open access
Semantic Scholar
Outcomes of COVID-19 in Patients With Cancer: Report From the National COVID Cohort Collaborative (N3C)
N. Sharafeldin, B. Bates, Qianqian Song, V. Madhira +10 more
2021Journal of Clinical Oncology109 citations Open access
Semantic Scholar
Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway
Zhiguo Chen, Juan Mo, J. Brosseau, T. Shipman +8 more
2018Cancer Discovery77 citations Open access
Semantic Scholar
Crowdsourced mapping of unexplored target space of kinase inhibitors
A. Cichońska, Balaguru Ravikumar, Robert J. Allaway, Fangping Wan +83 more
2020Nature Communications75 citations Open access
Semantic Scholar
Alternative models for sharing confidential biomedical data
J. Guinney, J. Saez-Rodriguez
2018Nature Biotechnology69 citations
Semantic Scholar
CRI iAtlas: an interactive portal for immuno-oncology research
J. Eddy, V. Thorsson, Andrew Lamb, D. Gibbs +8 more
2020F1000Research62 citations Open access
Semantic Scholar
The National COVID Cohort Collaborative: Clinical Characterization and Early Severity Prediction
Tellen D. Bennett, R. Moffitt, J. Hajagos, Benjamin R. C. Amor +41 more
2021medRxiv57 citations Open access
Semantic Scholar
A Community Challenge for Pancancer Drug Mechanism of Action Inference from Perturbational Profile Data
Eugene Douglass, Robert J. Allaway, B. Szalai, Wenyu Wang +24 more
2020bioRxiv54 citations Open access
Semantic Scholar
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease
M. Mason, C. Schinke, Christine L. P. Eng, F. Towfic +38 more
2019bioRxiv52 citations Open access
Semantic Scholar
Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1)
M. Fisher, David T. W. Jones, Yi-Mei Li, Xiao-Fan Guo +29 more
2021Acta Neuropathologica50 citations
Semantic Scholar
Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK
Long-Sheng Chang, J. Oblinger, A. Smith, M. Ferrer +36 more
2021PLoS ONE43 citations Open access
Semantic Scholar
Validation of a Transcriptome-Based Assay for Classifying Cancers of Unknown Primary Origin
J. Michuda, A. Breschi, J. Kapilivsky, K. Manghnani +14 more
2022Molecular Diagnosis & Therapy42 citations Open access
Semantic Scholar
Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells
M. Ferrer, Sara J. C. Gosline, M. Stathis, Xiaohu Zhang +12 more
2018Scientific Data36 citations Open access
Semantic Scholar
American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond—Lessons Learned and Member Institutions’ Perspectives
C. Micheel, S. Sweeney, M. LeNoue-Newton, F. André +9 more
2018JCO Clinical Cancer Informatics35 citations Open access
Semantic Scholar
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia
B. S. White, S. Khan, M. Mason, Muhammad Ammad-ud-din +13 more
2021npj Precision Oncology33 citations Open access
Semantic Scholar
A clinically and genomically annotated nerve sheath tumor biospecimen repository
K. Pollard, Jineta Banerjee, Xengie Doan, Jia-Wan Wang +13 more
2019Scientific Data33 citations Open access
Semantic Scholar
A community challenge to evaluate RNA-seq, fusion detection, and isoform quantification methods for cancer discovery
Allison L. Creason, David Haan, Kristen K. Dang, K. Chiotti +25 more
2021Cell Systems30 citations Open access
Semantic Scholar
Reproducible biomedical benchmarking in the cloud: lessons from crowd-sourced data challenges
Kyle Ellrott, Alex Buchanan, Allison L. Creason, M. Mason +10 more
2019Genome Biology29 citations Open access
Semantic Scholar
USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
Lei Sun, Jia Yu, J. Guinney, B. Qin +1 more
2023Molecular Cancer Research26 citations Open access
Semantic Scholar
A Crowdsourcing Approach to Develop Machine Learning Models to Quantify Radiographic Joint Damage in Rheumatoid Arthritis
Dong-Mei Sun, T. Nguyen, Robert J. Allaway, Jelai Wang +17 more
2021medRxiv26 citations Open access
Semantic Scholar
Community assessment of methods to deconvolve cellular composition from bulk gene expression
Brian S. White, A. de Reyniès, Aaron M. Newman, Joshua J. Waterfall +36 more
2024bioRxiv25 citations Open access
Semantic Scholar
Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer
Chang Xu, O. Nikolova, Ryan S. Basom, Ryan M. Mitchell +16 more
2018Clinical Cancer Research24 citations Open access
Semantic Scholar
Association of genetic ancestry with molecular tumor profiles in colorectal cancer
B. Rhead, D. Hein, Y. Pouliot, J. Guinney +2 more
2023Genome Medicine22 citations Open access
Semantic Scholar
Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data
J. Tanevski, Thin Nguyen, B. Truong, Nikos Karaiskos +34 more
2020Life Science Alliance22 citations Open access
Semantic Scholar
The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin
F. Rice, George Houk, J. Wymer, Sara J. C. Gosline +10 more
2019PLoS ONE22 citations Open access
Semantic Scholar
Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data
Xuan Liu, Sara J. C. Gosline, Lance T. Pflieger, Pierre Wallet +4 more
2021Briefings Bioinform.21 citations Open access
Semantic Scholar
Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1
Jineta Banerjee, Robert J. Allaway, Jaclyn N. Taroni, Aaron Baker +8 more
2020bioRxiv20 citations Open access
Semantic Scholar
Engaging a community to enable disease-centric data sharing with the NF Data Portal
Robert J. Allaway, S. La Rosa, S. Verma, L. Mangravite +4 more
2019Scientific Data16 citations Open access
Semantic Scholar
A Continuously Benchmarked and Crowdsourced Challenge for Rapid Development and Evaluation of Models to Predict COVID-19 Diagnosis and Hospitalization
Yao Yan, T. Schaffter, T. Bergquist, Thomas V. Yu +15 more
2021JAMA Network Open15 citations Open access
Semantic Scholar
Piloting a model-to-data approach to enable predictive analytics in health care through patient mortality prediction
T. Bergquist, Yao Yan, T. Schaffter, Thomas V. Yu +5 more
2020J. Am. Medical Informatics Assoc.14 citations Open access
Semantic Scholar
A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer
M. Mason, Óscar Lapuente-Santana, Anni S. Halkola, Wenyu Wang +41 more
2022bioRxiv13 citations Open access
Semantic Scholar
Use of clinical RNA-sequencing in the detection of actionable fusions compared to DNA-sequencing alone.
J. Michuda, B. H. Park, A. Cummings, S. Devarakonda +11 more
2022Journal of Clinical Oncology13 citations
Semantic Scholar
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
Zhaoping Xiong, Minji Jeon, Robert J. Allaway, Jaewoo Kang +17 more
2021bioRxiv13 citations Open access
Semantic Scholar
Probing the chemical–biological relationship space with the Drug Target Explorer
Robert J. Allaway, S. La Rosa, J. Guinney, Sara J. C. Gosline
2018bioRxiv11 citations Open access
Semantic Scholar
Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume I—conceptual challenges
S. Rutella, M. Cannarile, S. Gnjatic, B. Gomes +15 more
2020Journal for ImmunoTherapy of Cancer9 citations Open access
Semantic Scholar
Pursuing Better Biomarkers for Immunotherapy Response in Cancer Through a Crowdsourced Data Challenge.
B. Vincent, J. Szustakowski, P. Doshi, M. Mason +2 more
2021JCO Precision Oncology8 citations Open access
Semantic Scholar
A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction
Michael P. Menden, Dennis Wang, Yuanfang Guan, M. Mason +26 more
20188 citations
Semantic Scholar
Molecular response in newly diagnosed chronic-phase chronic myeloid leukemia: prediction modeling and pathway analysis
J. Radich, Matthew A. Wall, S. Branford, C. Campbell +19 more
2023Haematologica7 citations Open access
Semantic Scholar
Evaluation of crowdsourced mortality prediction models as a framework for assessing artificial intelligence in medicine
T. Bergquist, T. Schaffter, Yao Yan, Thomas V. Yu +17 more
2023J. Am. Medical Informatics Assoc.5 citations Open access
Semantic Scholar
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data
Eugene F. Douglass, Robert J. Allaway, B. Szalai, Wenyu Wang +24 more
2022Cell Reports Medicine5 citations Open access
Semantic Scholar

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