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Xia Bu · SciRah

Researcher profile · Semantic Scholar

Xia Bu

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Xia Bu — researcher profile on SciRah

h-index: 22
Works: 48
Citations: 8,160

Most-cited papers

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Peng Jiang, Sheng-Qing Gu, D. Pan, Jing-Xin Fu +11 more
2018Nature Medicine4,427 citations Open access
Semantic Scholar
Cyclin D-CDK4 kinase destabilizes PD-L1 via Cul3SPOP to control cancer immune surveillance
Jinfang Zhang, Xia Bu, Hai-Zhen Wang, Ya-Sheng Zhu +14 more
2017Nature778 citations Open access
Semantic Scholar
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
Yang Gao, N. T. Nihira, Xia Bu, C. Chu +23 more
2020Nature Cell Biology357 citations Open access
Semantic Scholar
T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells
R. DeKruyff, Xia Bu, A. Ballesteros, C. Santiago +8 more
2010Journal of Immunology343 citations Open access
Semantic Scholar
TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine
S. Jemielity, Jinyize J. Wang, Y. Chan, Asim A. Ahmed +8 more
2013PLoS Pathogens333 citations Open access
Semantic Scholar
RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance
Yanping Xiao, Sanhong Yu, Baogong Zhu, D. Bedoret +8 more
2014Journal of Experimental Medicine312 citations Open access
Semantic Scholar
Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
Xiaoming Dai, Xia Bu, Yang Gao, Jian-ping Guo +13 more
2021Molecules and Cells199 citations Open access
Semantic Scholar
Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade
S. Gu, Wubing Zhang, Xiao-Qing Wang, Peng Jiang +29 more
2021Cancer Discovery193 citations Open access
Semantic Scholar
The Hematopoiesis-Specific GTP-Binding Protein RhoH Is GTPase Deficient and Modulates Activities of Other Rho GTPases by an Inhibitory Function
Xiao-Yu Li, Xia Bu, B. Lu, H. Avraham +2 more
2002Molecular and Cellular Biology173 citations Open access
Semantic Scholar
USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy
Wenjun Xiong, Xue-Liang Gao, Tiantian Zhang, Bai-Shan Jiang +19 more
2022Nature Communications139 citations Open access
Semantic Scholar
A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
K. Mahoney, S. Shukla, N. Patsoukis, A. Chaudhri +13 more
2018Cancer Immunology and Immunotherapy124 citations Open access
Semantic Scholar
Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade
Mohammad Rashidian, M. LaFleur, V. Verschoor, Anushka Dongre +12 more
2019Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
Semantic Scholar
Author Correction: Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
Jinfang Zhang, Xia Bu, Hai-Zhen Wang, Ya-Sheng Zhu +14 more
2019Nature95 citations Open access
Semantic Scholar
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
Xiang-Ling Xiao, Jie Shi, Chuan He, Xia Bu +20 more
2023Nature Communications88 citations Open access
Semantic Scholar
Apoptotic Cells Activate NKT Cells through T Cell Ig-Like Mucin-Like–1 Resulting in Airway Hyperreactivity
Hyun-Hee Lee, E. Meyer, S. Goya, M. Pichavant +11 more
2010Journal of Immunology82 citations Open access
Semantic Scholar
PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity
Jing Liu, Xia Bu, C. Chu, Xiaoming Dai +4 more
2023Nature Communications81 citations Open access
Semantic Scholar
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy
Haisheng Yu, Jing Liu, Xia Bu, Zhiqiang Ma +22 more
2023Cell Chemical Biology78 citations Open access
Semantic Scholar
Learning from PD-1 Resistance: New Combination Strategies
Xia Bu, K. Mahoney, G. Freeman
2016Trends in Molecular Medicine73 citations Open access
Semantic Scholar
Process elongation of oligodendrocytes is promoted by the Kelch‐related actin‐binding protein Mayven
Shu-Xian Jiang, H. Avraham, Shin-Young Park, Tae-Aug Kim +3 more
2005Journal of Neurochemistry35 citations
Semantic Scholar
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
A. Chaudhri, Xia Bu, Yunfei Wang, Michael Gomez +8 more
2023Frontiers in Immunology28 citations Open access
Semantic Scholar
Immune Checkpoint Blockade in Breast Cancer Therapy.
Xia Bu, Yi-Hui Yao, Xiaoyu Li
2017Advances in Experimental Medicine and Biology24 citations
Semantic Scholar
Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
S. Gu, Xiao-Qing Wang, Xi-Hao Hu, Peng Jiang +22 more
2020Genome Biology23 citations Open access
Semantic Scholar
Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells
Xia Bu, H. Avraham, Xiao-Yu Li, B. Lim +4 more
2005Oncogene21 citations Open access
Semantic Scholar
Monitoring PD-1 phosphorylation to evaluate PD-1 signaling during anti-tumor immune responses
Xia Bu, Vikram R. Juneja, C. Reynolds, K. Mahoney +11 more
2021Cancer immunology research20 citations Open access
Semantic Scholar
Progress in Vaccine Therapies for Breast Cancer.
Xiaoyu Li, Xia Bu
2017Advances in Experimental Medicine and Biology13 citations
Semantic Scholar
Abstract B077: Signatures of T-cell dysfunction and exclusion predict cancer immunotherapy response
Peng Jiang, Sheng-Qing Gu, D. Pan, Jing-Xin Fu +11 more
2019Mutational Analysis and Predicting Response to Immunotherapy10 citations
Semantic Scholar
Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma.
Russell J. Ferland, Xiao-Yu Li, J. Buhlmann, Xia Bu +2 more
2005Brain Research9 citations
Semantic Scholar
Destruction of VISTA by TRIM25 ablation in T cells potentiates cancer immunotherapy
Yi-Shuang Sun, Zi-Jian Zhang, Haiou Li, Xia Bu +24 more
2025Cell Research6 citations
Semantic Scholar
Targeted destruction of VISTA boosts anti-tumor immunotherapy
Li Chen, Xia Bu, Yi-Shuang Sun, Dao-Yuan Huang +22 more
2025Cell Research6 citations Open access
Semantic Scholar
CD47 destabilization via manipulating the SPOP-USP2 axis augments macrophage phagocytosis and cancer immunotherapy
Pei-Qiang Yan, Xia Bu, Tao Hou, Li Chen +13 more
2026Journal for ImmunoTherapy of Cancer4 citations
Semantic Scholar
Efficacy and safety of rituximab in marginal zone lymphoma : a meta-analysis of 13 studies
Fuli Fan, Wei Wang, Guang-Lun Li, Xiaoyan Ju +6 more
20162 citations
Semantic Scholar
Polyfunctional Effector PD-1+ CD8+ T Cells and M1 Macrophages Promote Immune Checkpoint Blockade Response in Richter Syndrome Mouse Models
E. ten Hacken, Johan Gustafsson, Chiara Tomasoni, Gabriela Brunsting Hoffmann +15 more
2024Blood1 citations
Semantic Scholar
Heterogeneity of PD-1+regulatory T Cells after Low-Dose IL-2 Therapy for Patients with Chronic Graft-Versus-Host Disease
Shuntaro Ikegawa, Takeru Asano, Bohoon Shim, M. Borji +19 more
2024Blood1 citations
Semantic Scholar
Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
S. Gu, Xiao-Qing Wang, Xi-Hao Hu, Peng Jiang +22 more
2020Genome Biology1 citations Open access
Semantic Scholar
TIM-3- and TIM-4-mediated phagocytosis of apoptotic cells induces cytokine production in peritoneal macrophages (100.55)
Xia Bu, R. DeKruyff, D. Umetsu, G. Freeman
2011Journal of Immunology1 citations
Semantic Scholar
This information is current as of Apoptotic Cells Phosphatidylserine and Mediate Phagocytosis Allelic Variants Differentially Recognize T Cell / Transmembrane , Ig , and Mucin-3
R. DeKruyff, Xia Bu, A. Ballesteros, César de Miguel Santiago +8 more
20101 citations
Semantic Scholar
TIM-4 mediated phagocytosis of apoptotic cells induces regulatory cytokine secretion by mouse peritoneal macrophages (136.47)
Xia Bu, Baogong Zhu, D. Umetsu, R. DeKruyff +1 more
2010Journal of Immunology1 citations
Semantic Scholar
TIM-3 is a receptor for phosphatidylserine and allelic variants differentially mediate uptake of apoptotic cells (130.41)
Xia Bu, Angela Ballesterous, Yee-Ling E. Chim, C. Santiago +5 more
2010Journal of Immunology1 citations
Semantic Scholar
Author Correction: ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
Xiangling Xiao, Jie Shi, Chuan He, Xia Bu +20 more
2025Nature Communications0 citations Open access
Semantic Scholar
Low Dose IL-2 Therapy in Patients with Chronic Gvhd Induces PD-1+treg That Are Highly Activated, Immune Suppressive, and Proapoptotic
Shuntaro Ikegawa, Takeru Asano, Haesook T. Kim, G. Freeman +13 more
2022Transplantation and Cellular Therapy0 citations Open access
Semantic Scholar
Abstract 65: Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade
S. Gu, Wubing Zhang, Xiao-Qing Wang, Peng Jiang +29 more
2021Immunology0 citations
Semantic Scholar
Intracellular Signaling triggered by engagement of PD-1 by PD-L1
Xia Bu, Melissa T. Bu, Ping Hua, Baogong Zhu +2 more
2020Journal of Immunology0 citations
Semantic Scholar
Abstract 3779: Clonal tracing reveals different mechanisms of resistance to immune checkpoint blockade
Sheng-Qing Gu, Xi-Hao Hu, Xiao-Qing Wang, Peng Jiang +7 more
2019Tumor Biology0 citations Open access
Semantic Scholar
Monitoring PD-1 Signaling in Tumor Infiltrating Lymphocytes
Xia Bu, Vikram R. Juneja, Katheleen M. Mahoney, Carol G. Renolds +10 more
2019Journal of Immunology0 citations
Semantic Scholar
Abstract A077: Microenvironmental factors shape resistance patterns to immune checkpoint blockade
Sheng Gu, Xi-Hao Hu, Xiao-Qing Wang, Ziyi Li +6 more
2019Tackling the Tumor Microenvironment: Beyond T-cells0 citations
Semantic Scholar
Abstract A12: Identification of resistance to immune checkpoint blockade
Sheng-Qing Gu, Ziyi Li, Xia Bu, Xiao-Fang Xing +3 more
2018Checkpoints and Immunomodulation0 citations
Semantic Scholar
Evolutionary origins and structural analysis of phosphatidylserine binding by the TIM gene family (CAM5P.244)
Jennifer Jones, A. Brandmaier, S. Umetsu, Xia Bu +3 more
2014Journal of Immunology0 citations
Semantic Scholar
This information is current as Airway Hyperreactivity 1 Resulting in − T Cell Ig-Like Mucin-Like Apoptotic Cells Activate NKT Cells through
Hyun-Hee Lee, E. Meyer, S. Goya, M. Pichavant +10 more
20100 citations
Semantic Scholar

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