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S. Lesage · SciRah

Researcher profile · Semantic Scholar

S. Lesage

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S. Lesage — researcher profile on SciRah

h-index: 37
Works: 139
Citations: 5,961

Most-cited papers

Aire regulates negative selection of organ-specific T cells
A. Liston, S. Lesage, Judith Wilson, L. Peltonen +1 more
2003Nature Immunology833 citations
Semantic Scholar
Gene Dosage–limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity
A. Liston, D. Gray, S. Lesage, A. Fletcher +6 more
2004Journal of Experimental Medicine322 citations Open access
Semantic Scholar
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.
Jesse E Jun, L. E. Wilson, C. Vinuesa, S. Lesage +11 more
2003Immunity318 citations Open access
Semantic Scholar
The importance of dendritic cells in maintaining immune tolerance
Cindy Audiger, M. J. Rahman, T. Yun, K. Tarbell +1 more
2017Journal of Immunology234 citations Open access
Semantic Scholar
Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.
A. Liston, S. Lesage, D. Gray, L. O'Reilly +10 more
2004Immunity185 citations Open access
Semantic Scholar
Engraftment of allogeneic mesenchymal stem cells in the bone marrow of a patient with severe idiopathic aplastic anemia improves stroma
L. Fouillard, M. Bensidhoum, D. Bories, H. Bonte +9 more
2003Leukemia182 citations Open access
Semantic Scholar
Genetic Predisposition for Beta Cell Fragility Underlies Type 1 and Type 2 Diabetes
J. Dooley, L. Tian, Susann Schonefeldt, V. Delghingaro-Augusto +25 more
2016Nature Genetics134 citations Open access
Semantic Scholar
Expression of the self‐marker CD47 on dendritic cells governs their trafficking to secondary lymphoid organs
Van Quang Vu, S. Lesage, S. Bouguermouh, Patrick Gautier +5 more
2006EMBO Journal102 citations Open access
Semantic Scholar
A comprehensive review of the phenotype and function of antigen-specific immunoregulatory double negative T cells.
Erin E. Hillhouse, S. Lesage
2013Journal of Autoimmunity98 citations
Semantic Scholar
IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking*
D. Sivanesan, C. Beauchamp, Christiane Quinou, Jonathan M. Lee +4 more
2016Journal of Biological Chemistry80 citations Open access
Semantic Scholar
Genetic lesions in T‐cell tolerance and thresholds for autoimmunity
A. Liston, S. Lesage, D. Gray, R. Boyd +1 more
2005Immunological Reviews73 citations Open access
Semantic Scholar
LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy
D. Planas, A. Pagliuzza, Rosalie Ponte, A. Fert +14 more
2021EBioMedicine63 citations Open access
Semantic Scholar
T Cell Tolerance to a Neo-Self Antigen Expressed by Thymic Epithelial Cells: The Soluble Form Is More Effective Than the Membrane-Bound Form
Mei-Fen Zhang, M. Vacchio, B. Vistica, S. Lesage +6 more
2003Journal of Immunology58 citations Open access
Semantic Scholar
Interleukin‐10 limits the expansion of immunoregulatory CD4−CD8− T cells in autoimmune‐prone non‐obese diabetic mice
Erin E. Hillhouse, C. Beauchamp, G. Chabot-Roy, V. Dugas +1 more
2010Immunology and Cell Biology51 citations
Semantic Scholar
The orphan nuclear receptor NR4A3 controls the differentiation of monocyte-derived dendritic cells following microbial stimulation
S. Boulet, Jean Daudelin, Livia Odagiu, A. Pelletier +4 more
2019Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
C. Whyte, Kailash Singh, O. Burton, M. Aloulou +21 more
2020bioRxiv49 citations Open access
Semantic Scholar
Upregulated IL-32 Expression And Reduced Gut Short Chain Fatty Acid Caproic Acid in People Living With HIV With Subclinical Atherosclerosis
M. El-Far, M. Durand, Isabelle Turcotte, Etienne Larouche-Anctil +28 more
2021Frontiers in Immunology47 citations Open access
Semantic Scholar
Abnormal differentiation of B cells and megakaryocytes in patients with Roifman syndrome
Jessica Heremans, J. Garcia-Perez, E. Turro, Susan M. Schlenner +17 more
2018Journal of Allergy and Clinical Immunology47 citations Open access
Semantic Scholar
Cutting Edge: CD47 Controls the In Vivo Proliferation and Homeostasis of Peripheral CD4+CD25+Foxp3+ Regulatory T Cells That Express CD1031
Van Quang Vu, J. Darwiche, Marianne Raymond, S. Lesage +3 more
2008Journal of Immunology45 citations Open access
Semantic Scholar
The NOD Mouse Beyond Autoimmune Diabetes
Anne Aubin, Félix Lombard-Vadnais, R. Collin, Holly A. Aliesky +2 more
2022Frontiers in Immunology44 citations Open access
Semantic Scholar
Implication of the CD47 pathway in autoimmune diabetes.
V. Dugas, C. Beauchamp, G. Chabot-Roy, Erin E. Hillhouse +1 more
2010Journal of Autoimmunity43 citations
Semantic Scholar
The Dichotomous Pattern of IL-12R and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation
Gaëlle Chognard, L. Bellemare, A. Pelletier, M. Domínguez-Punaro +11 more
2014PLoS ONE42 citations Open access
Semantic Scholar
Immunoregulatory CD4-CD8- T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer
Erin E. Hillhouse, J. Delisle, S. Lesage
2013Front. Immun.38 citations Open access
Semantic Scholar
Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity*
M. Tetreault, B. Bourdin, J. Briot, Émilie Segura +3 more
2016Journal of Biological Chemistry37 citations Open access
Semantic Scholar
BMP9 signaling promotes the normalization of tumor blood vessels
C. Viallard, Cindy Audiger, N. Popovic, Naoufal Akla +6 more
2020Oncogene36 citations
Semantic Scholar
Redefining interferon-producing killer dendritic cells as a novel intermediate in NK-cell differentiation.
F. Guimont-Desrochers, G. Boucher, Zhongjun Dong, M. Dupuis +2 more
2012Blood36 citations
Semantic Scholar
MARCH1 E3 Ubiquitin Ligase Dampens the Innate Inflammatory Response by Modulating Monocyte Functions in Mice
Tristan Galbas, M. Raymond, Antoine Sabourin, M. Bourgeois-Daigneault +7 more
2017Journal of Immunology33 citations
Semantic Scholar
Molecular and genetic parameters defining T‐cell clonal selection
N. Labrecque, T. Baldwin, S. Lesage
2011Immunology and Cell Biology33 citations
Semantic Scholar
The Potential Causes of Cystic Fibrosis-Related Diabetes
L. Coderre, Lyna Debieche, Joelle Plourde, R. Rabasa-Lhoret +1 more
2021Frontiers in Endocrinology31 citations Open access
Semantic Scholar
Functional Characterization of CaVα2δ Mutations Associated with Sudden Cardiac Death*
B. Bourdin, Behzad Shakeri, M. Tetreault, R. Sauvé +2 more
2014Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs
Fiona C. Simpson, Christopher D. McTiernan, M. M. Islam, O. Buznyk +14 more
2021Communications Biology30 citations Open access
Semantic Scholar
Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis
Charlotte Girondel, Lévesque Kim, M. Langlois, S. Pasquin +7 more
2020Oncogene29 citations
Semantic Scholar
Common Heritable Immunological Variations Revealed in Genetically Diverse Inbred Mouse Strains of the Collaborative Cross
R. Collin, L. Balmer, G. Morahan, S. Lesage
2018Journal of Immunology29 citations
Semantic Scholar
The Role of Endoplasmic Reticulum Stress in Nonimmune Diabetes: NOD.k iHEL, a Novel Model of β Cell Death
L. Socha, D. Silva, S. Lesage, C. Goodnow +1 more
200329 citations
Semantic Scholar
Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response.
C. Quiniou, M. Domínguez-Punaro, Frank Cloutier, Atefeh Erfani +14 more
2014American Journal of Physiology. Regulatory Integrative and Comparative Physiology28 citations
Semantic Scholar
Flt3L-Mediated Expansion of Plasmacytoid Dendritic Cells Suppresses HIV Infection in Humanized Mice.
T. Pham, O. Méziane, M. Miah, Olga Volodina +10 more
2019Cell Reports22 citations Open access
Semantic Scholar
Double-Negative T Cell Levels Correlate with Chronic Graft-versus-Host Disease Severity.
Erin E. Hillhouse, S. Thiant, M. Moutuou, Félix Lombard-Vadnais +7 more
2019Biology of Blood and Marrow Transplantation20 citations Open access
Semantic Scholar
Cutting Edge: Genetic Characterization of IFN-Producing Killer Dendritic Cells1
F. Guimont-Desrochers, Z. Cappello, M. Chagnon, M. Mcduffie +1 more
2009Journal of Immunology20 citations Open access
Semantic Scholar
Restoring T Cell Homeostasis After Allogeneic Stem Cell Transplantation; Principal Limitations and Future Challenges
M. Moutuou, Gabriel Pagé, Intesar Zaid, S. Lesage +1 more
2018Frontiers in Immunology19 citations Open access
Semantic Scholar
Merocytic Dendritic Cells Compose a Conventional Dendritic Cell Subset with Low Metabolic Activity
Cindy Audiger, Adrien Fois, Alyssa L. Thomas, Edith M. Janssen +2 more
2020Journal of Immunology18 citations Open access
Semantic Scholar
The Mouse Idd2 Locus Is Linked to the Proportion of Immunoregulatory Double-Negative T Cells, a Trait Associated with Autoimmune Diabetes Resistance
R. Collin, V. Dugas, A. Pelletier, G. Chabot-Roy +1 more
2014Journal of Immunology18 citations
Semantic Scholar
An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation
R. Collin, Charles St-Pierre, Lorie Guilbault, Victor Mullins-Dansereau +8 more
2017Journal of Immunology17 citations Open access
Semantic Scholar
Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes
F. Dion, C. Dumayne, N. Henley, Stéphanie Beauchemin +6 more
2017PLoS ONE16 citations Open access
Semantic Scholar
The Idd13 congenic interval defines the number of merocytic dendritic cells, a novel trait associated with autoimmune diabetes susceptibility.
A. Pelletier, S. Lesage
2013Journal of Autoimmunity15 citations
Semantic Scholar
The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of beta cell death.
L. Socha, D. Silva, S. Lesage, C. Goodnow +1 more
2003Annals of the New York Academy of Sciences15 citations
Semantic Scholar
High‐level intrathymic thyrotrophin receptor expression in thyroiditis‐prone mice protects against the spontaneous generation of pathogenic thyrotrophin receptor autoantibodies
S. Mclachlan, Holly A. Aliesky, Bianca Banuelos, S. Lesage +2 more
2017Clinical and Experimental Immunology14 citations Open access
Semantic Scholar
Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice
Erin E. Hillhouse, R. Collin, G. Chabot-Roy, Marie-Josée Guyon +4 more
2013Journal of Diabetes Research14 citations Open access
Semantic Scholar
Absence of CD47 in vivo influences thymic dendritic cell subset proportions but not negative selection of thymocytes.
F. Guimont-Desrochers, C. Beauchamp, G. Chabot-Roy, V. Dugas +7 more
2009International Immunology14 citations
Semantic Scholar
Revisiting the Prominent Anti-Tumoral Potential of Pre-mNK Cells
F. Guimont-Desrochers, S. Lesage
2013Frontiers in Immunology13 citations Open access
Semantic Scholar
A cell death pathway induced by antibody-mediated cross-linking of CD45 on lymphocytes.
A. Steff, M. Fortin, F. Philippoussis, S. Lesage +3 more
2003Critical Reviews in Immunology13 citations
Semantic Scholar

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A. Liston×7
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