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Susan M. Schlenner · SciRah

Researcher profile · Semantic Scholar

Susan M. Schlenner

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Susan M. Schlenner — researcher profile on SciRah

h-index: 30
Works: 74
Citations: 3,723

Most-cited papers

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
Katrin Busch, Kay Klapproth, Melania Barile, M. Flossdorf +5 more
2015Nature665 citations
Semantic Scholar
Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus.
Susan M. Schlenner, V. Madan, Katrin Busch, A. Tietz +5 more
2010Immunity336 citations Open access
Semantic Scholar
Hematopoietic stem cell niches produce lineage-instructive signals to control multipotent progenitor differentiation
A. C. Gomes, T. Hara, Vivian Y. Lim, D. Herndler-Brandstetter +10 more
2016Immunity254 citations Open access
Semantic Scholar
Anti-apoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
Wim Pierson, Bénédicte Cauwe, A. Policheni, Susan M. Schlenner +16 more
2013Nature Immunology233 citations Open access
Semantic Scholar
Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin
L. Schneider, Susan M. Schlenner, Thorsten B. Feyerabend, M. Wunderlin +1 more
2007Journal of Experimental Medicine160 citations Open access
Semantic Scholar
Necroptosis in Immuno-Oncology and Cancer Immunotherapy
J. Sprooten, Pieter De Wijngaert, I. Vanmeerbeek, Shaun Martin +7 more
2020Cells156 citations Open access
Semantic Scholar
Cancer immunotherapies transition endothelial cells into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop
Yichao Hua, G. Vella, F. Rambow, Elizabeth Allen +19 more
2022Cancer Cell150 citations Open access
Semantic Scholar
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.
M. Akahoshi, Chang H. Song, A. Piliponsky, M. Metz +8 more
2011Journal of Clinical Investigation146 citations Open access
Semantic Scholar
The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity
J. Dooley, J. Garcia-Perez, J. Sreenivasan, Susan M. Schlenner +12 more
2015Diabetes137 citations Open access
Semantic Scholar
Genetic Predisposition for Beta Cell Fragility Underlies Type 1 and Type 2 Diabetes
J. Dooley, L. Tian, Susann Schonefeldt, V. Delghingaro-Augusto +25 more
2016Nature Genetics134 citations Open access
Semantic Scholar
Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation*
Ananya Roy, Goutham V. Ganesh, H. Sippola, Sara Bolin +8 more
2013Journal of Biological Chemistry126 citations Open access
Semantic Scholar
The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Oliver T. Burton, Orian Bricard, Samar H. K. Tareen, Václav Gergelits +14 more
2024Immunity83 citations Open access
Semantic Scholar
IL-2 immunotherapy for targeting regulatory T cells in autoimmunity
Valentina Lykhopiy, Vanshika Malviya, S. Humblet-Baron, Susan M. Schlenner
2023Genes and Immunity78 citations Open access
Semantic Scholar
The inflammatory response following an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5
George Younan, F. Suber, W. Xing, Tong Shi +10 more
2010Journal of Immunology76 citations Open access
Semantic Scholar
Targeting conserved TIM3+VISTA+ tumor-associated macrophages overcomes resistance to cancer immunotherapy
I. Vanmeerbeek, S. Naulaerts, J. Sprooten, R. S. Laureano +14 more
2024Science Advances73 citations Open access
Semantic Scholar
Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop.
Yichao Hua, G. Vella, F. Rambow, Elizabeth Allen +19 more
2023Cancer Cell63 citations Open access
Semantic Scholar
Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
J. Sprooten, I. Vanmeerbeek, A. Datsi, J. Govaerts +21 more
2024Cell Reports Medicine62 citations Open access
Semantic Scholar
Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3+ and Foxp3− T cells
Dean Franckaert, J. Dooley, E. Roos, S. Floess +6 more
2014Immunology and Cell Biology60 citations Open access
Semantic Scholar
Early T cell development and the pitfalls of potential.
Susan M. Schlenner, H. Rodewald
2010Trends in immunology56 citations
Semantic Scholar
The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program
O. Burton, Orian Bricard, Samar H. K. Tareen, Václav Gergelits +13 more
2023bioRxiv49 citations Open access
Semantic Scholar
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
C. Whyte, Kailash Singh, O. Burton, M. Aloulou +21 more
2020bioRxiv49 citations Open access
Semantic Scholar
Abnormal differentiation of B cells and megakaryocytes in patients with Roifman syndrome
Jessica Heremans, J. Garcia-Perez, E. Turro, Susan M. Schlenner +17 more
2018Journal of Allergy and Clinical Immunology47 citations Open access
Semantic Scholar
A kindred with Mutant IKAROS and autoimmunity.
Erika Van Nieuwenhove, J. Garcia-Perez, C. Helsen, Princess Rodriguez +13 more
2018Journal of Allergy and Clinical Immunology41 citations Open access
Semantic Scholar
A Role for Serglycin Proteoglycan in Mast Cell Apoptosis Induced by a Secretory Granule-mediated Pathway*
F. Melo, I. Waern, E. Rönnberg, M. Åbrink +7 more
2010Journal of Biological Chemistry41 citations Open access
Semantic Scholar
The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells
Aleksandra Brajic, Dean Franckaert, O. Burton, S. Bornschein +6 more
2018Frontiers in Immunology40 citations Open access
Semantic Scholar
Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia
Erika Van Nieuwenhove, John S. Barber, Julika Neumann, E. Smeets +26 more
2020Journal of Allergy and Clinical Immunology38 citations Open access
Semantic Scholar
Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
Susan M. Schlenner, Benno Weigmann, Qing-Guo Ruan, You-Hai H. Chen +1 more
2012Journal of Experimental Medicine37 citations Open access
Semantic Scholar
Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice
A. V. van Nieuwenhuijze, J. Dooley, S. Humblet-Baron, J. Sreenivasan +4 more
2017Cellular and Molecular Life Sciences35 citations
Semantic Scholar
Regulatory T‐cell stability and functional plasticity in health and disease
Vanshika Malviya, L. Yshii, S. Junius, A. Garg +2 more
2022Immunology and Cell Biology33 citations Open access
Semantic Scholar
Mast cells limit extracellular levels of IL-13 via a serglycin proteoglycan-serine protease axis
I. Waern, I. Karlsson, Michael Thorpe, Susan M. Schlenner +6 more
2012Biological chemistry32 citations Open access
Semantic Scholar
NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology
Susan M. Schlenner, Emanuela Pasciuto, V. Lagou, O. Burton +13 more
2018Annals of the Rheumatic Diseases30 citations Open access
Semantic Scholar
Faculty Opinions recommendation of CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia.
H. Rodewald, Susan M. Schlenner
200926 citations
Semantic Scholar
Unstable regulatory T cells, enriched for naïve and Nrp1neg cells, are purged after fate challenge
S. Junius, Adamantios V. Mavrogiannis, Pierre Lemaitre, M. Gerbaux +10 more
2021Science immunology24 citations Open access
Semantic Scholar
Kit is essential for PMA-inflammation-induced mast-cell accumulation in the skin.
C. Waskow, S. Bartels, Susan M. Schlenner, Céline F. Costa +1 more
2007Blood23 citations Open access
Semantic Scholar
Disrupted Ca2+ homeostasis and immunodeficiency in patients with functional IP3 receptor subtype 3 defects
Julika Neumann, Erika Van Nieuwenhove, L. Terry, F. Staels +17 more
2022Cellular & Molecular Immunology17 citations Open access
Semantic Scholar
Premature thymic involution is independent of structural plasticity of the thymic stroma
Dean Franckaert, Susan M. Schlenner, Nathalie Heirman, J. Gill +6 more
2015European Journal of Immunology15 citations Open access
Semantic Scholar
A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease
L. Van Horebeek, Kelly Hilven, Klara Mallants, A. V. van Nieuwenhuijze +7 more
2018Human Molecular Genetics13 citations Open access
Semantic Scholar
A novel Zap70 mutation with reduced protein stability demonstrates the rate‐limiting threshold for Zap70 in T‐cell receptor signalling
Bénédicte Cauwe, L. Tian, Dean Franckaert, Wim Pierson +3 more
2014Immunology13 citations Open access
Semantic Scholar
The Thymic Microenvironment Differentially Regulates Development and Trafficking of Invariant NKT Cell Sublineages
Michael B. Drennan, S. Govindarajan, K. De Wilde, Susan M. Schlenner +4 more
2014Journal of Immunology12 citations Open access
Semantic Scholar
The thymoprotective function of leptin is indirectly mediated via suppression of obesity
J. Sreenivasan, Susan M. Schlenner, Dean Franckaert, J. Dooley +1 more
2015Immunology10 citations Open access
Semantic Scholar
A metabolic gene survey pinpoints fucosylation as a key pathway underlying the suppressive function of regulatory T cells in cancer
Sotiria Pinioti, Himal Sharma, Nina C Flerin, Qian Yu +10 more
2023Cancer immunology research8 citations Open access
Semantic Scholar
Selective ablation of thymic and peripheral Foxp3+ regulatory T cell development
A. Yilmazer, Dimitra Maria Zevla, Rikke Malmkvist, C. Rodriguez +7 more
2023bioRxiv6 citations Open access
Semantic Scholar
Homozygous DBF4 mutation as a cause for severe congenital neutropenia.
Mathijs Willemsen, John S. Barber, Erika Van Nieuwenhove, F. Staels +17 more
2023Journal of Allergy and Clinical Immunology6 citations Open access
Semantic Scholar
CTLA4-Ig Effectively Controls Clinical Deterioration and Immune Condition in a Murine Model of Foxp3 Deficiency
M. Gerbaux, E. Roos, Mathijs Willemsen, F. Staels +8 more
2023Journal of Clinical Immunology6 citations Open access
Semantic Scholar
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells
Libao Liu, Laurie Rangan, Nathan Vanalken, Qian-Qian Kong +4 more
2024Cancer Immunology and Immunotherapy5 citations Open access
Semantic Scholar
The phosphatase regulator NIPP1 restrains chemokine-driven skin inflammation
Iris Verbinnen, Marloes C. M. Jonkhout, Kif Liakath-Ali, Kathelijne Szekér +7 more
2020Journal of Investigative Dermatology5 citations Open access
Semantic Scholar
The Inflammatory Response after an Epidermal Burn Depends on the Activities of Mouse Mast Cell Proteases
G. Younan, F. Suber, W. Xing, Tong Shi +10 more
20105 citations
Semantic Scholar
OTULIN haploinsufficiency predisposes to environmentally directed inflammation
F. Staels, Leoni Bücken, Leana De Vuyst, Mathijs Willemsen +16 more
2024Frontiers in Immunology4 citations Open access
Semantic Scholar
A ZAP‐70 kinase domain variant prevents thymocyte‐positive selection despite signalling CD69 induction
O. Siggs, Adèle L. Yates, Susan M. Schlenner, A. Liston +2 more
2014Immunology4 citations Open access
Semantic Scholar
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells.
K. De Vos, Adamantios V. Mavrogiannis, Justina Clarinda Wolters, Susan M. Schlenner +9 more
2024Biochemical Pharmacology3 citations Open access
Semantic Scholar

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