Zhen-Kun Zhuang

Most-cited papers

1. Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients

   Linnan Zhu, Peng-Hui Yang, Yingze Zhao, Zhen-Kun Zhuang +40 more

   2020Immunity354 citations Open access

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2. Cell transcriptomic atlas of the non-human primate Macaca fascicularis

   Lei Han, Xiaoyu Wei, Chuan-Yu Liu, G. Volpe +73 more

   2021Nature201 citations Open access

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3. Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex.

   Ao Chen, Yi-Di Sun, Ying Lei, C. Li +101 more

   2023Cell196 citations Open access

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4. The trans-omics landscape of COVID-19

   Peng Wu, Dongsheng Chen, W. Ding, Ping Wu +65 more

   2020Nature Communications104 citations Open access

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5. Multiregion single‐cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancer

   Wei Wang, Yu Zhong, Zhen-Kun Zhuang, Jiarui Xie +25 more

   2021Clinical and Translational Medicine83 citations Open access

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6. Cross-species single-cell spatial transcriptomic atlases of the cerebellar cortex

   Shijie Hao, Xiaojia Zhu, Zhi Huang, Qianqian Yang +78 more

   2024Science45 citations Open access

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7. Spatially resolved gene regulatory and disease-related vulnerability map of the adult Macaque cortex

   Ying Lei, Mengnan Cheng, Zihao Li, Zhen-Kun Zhuang +48 more

   2022Nature Communications39 citations Open access

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8. Molecular Profiles and Metastasis Markers in Chinese Patients with Gastric Carcinoma

   Chao Chen, Chun-Mei Shi, Xiaochun Huang, Jian-Wei Zheng +12 more

   2019Scientific Reports39 citations Open access

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9. Molecular pathways and diagnosis in spatially resolved Alzheimer's hippocampal atlas.

   Pan Wang, Lei Han, Li-Fang Wang, Qu-Yuan Tao +43 more

   2025Neuron31 citations

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10. Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

    Lei Han, Xiaoyu Wei, Chuan-Yu Liu, G. Volpe +36 more

    2020bioRxiv31 citations Open access

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11. Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines

    Shan-Shan Wang, Jiarui Xie, Xuan-Xuan Zou, Taotao Pan +14 more

    2022iScience22 citations Open access

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12. Immune response and homeostasis mechanism following administration of BBIBP-CorV SARS-CoV-2 inactivated vaccine

    Jianhua Yin, Yingze Zhao, F. Huang, Yun-Kai Yang +44 more

    2022Innovation (Cambridge (Mass.))17 citations Open access

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13. Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

    Ao Chen, Yi-Di Sun, Ying Lei, Chao Li +94 more

    2022bioRxiv12 citations Open access

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14. Potential association factors for developing effective peptide-based cancer vaccines

    Chongming Tom Jiang, Jian-Rong Li, Wei Zhang, Zhen-Kun Zhuang +5 more

    2022Frontiers in Immunology12 citations Open access

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15. A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets

    Si-qi Qiu, R. Hong, Zhen-Kun Zhuang, Yuan Li +23 more

    2019bioRxiv12 citations Open access

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16. A simple, rapid, and practical method for single-cell proteomics based on mass-adaptive coating of synthetic peptides.

    Siqi Li, Kaichan Su, Zhen-Kun Zhuang, Qing Qin +10 more

    2021Science Bulletin8 citations

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17. Spatial and single-nucleus transcriptomics decoding the molecular landscape and cellular organization of avian optic tectum

    K. Liao, Ya Xiang, Fubaoqian Huang, Maolin Huang +10 more

    2024iScience7 citations Open access

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18. A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus

    Fei Wang, Qumiao Xu, Zhen-Kun Zhuang, Ziyi Li +6 more

    2020Cellular & Molecular Immunology7 citations Open access

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19. Genomic evolution reshapes cell type diversification in the amniote brain

    Duoyuan Chen, Zhen-Kun Zhuang, Maolin Huang, Yun-Qi Huang +34 more

    2024bioRxiv6 citations

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20. stTransfer enables transfer of single-cell annotations to spatial transcriptomics with single-cell resolution

    Tao Zhou, Lin Xiang, Kuo Liao, Youzhe He +2 more

    2025Cell Reports Methods4 citations

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21. Evolutionary convergence and divergence of hippocampal cytoarchitecture between rodents and primates revealed by single-cell spatial transcriptomics

    Tian-Yi Fei, Yu Dong, Xiaojuan Gou, Jia-Hao Zhang +71 more

    2026National Science Review3 citations

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22. Deciphering the distinct transcriptomic and gene regulatory map in adult macaque basal ganglia cells

    Zihao Li, Yu-Nong Sun, Ling-Jun Ding, Jing Yang +13 more

    2022GigaScience3 citations Open access

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23. Molecular profiles and mutation burden analysis in Chinese patients with gastric carcinoma

    Chao Chen, Chun-Mei Shi, Xiaochun Huang, Jian-Wei Zheng +12 more

    2018bioRxiv3 citations Open access

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24. Cross-species single-cell transcriptomics reveals neuronal similarities and heterogeneity in amniote pallium

    Fubaoqian Huang, Kuo Liao, Yunong Sun, Zi-Hao Li +9 more

    2025Zoological Research2 citations Open access

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25. Spatially resolved gene regulatory and disease vulnerability map of the adult Macaque cortex

    Ying Lei, Mengnan Cheng, Zihao Li, Zhen-Kun Zhuang +47 more

    2022bioRxiv2 citations Open access

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26. Single-nucleus profiling decoding the subcortical visual pathway evolution of vertebrates

    Kuo Liao, Ya Xiang, You-Ning Lin, Pingfang Liao +3 more

    2025iScience1 citations Open access

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27. Abstract LB051: The landscape of peptide vaccinein clinical trials for cancer

    Chongming Tom Jiang, Geng Liu, Wei Zhang, Zhen-Kun Zhuang +5 more

    2021Clinical research1 citations

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28. Single-cell Approach to Generate Functional TCR-Ts: A Potential Accelerator of TCR-T Cell Therapy for Infectious Diseases

    Qumiao Xu, Ziyi Li, Fei Wang, Zhen-Kun Zhuang +4 more

    2020Journal of cellular immunology1 citations Open access

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29. Single-cell Multi-omics reveal heterogeneity and metastasis potential in different liver cancer cell lines

    Shan-Shan Wang, Jiarui Xie, Xuan-Xuan Zou, Taotao Pan +6 more

    2020bioRxiv1 citations Open access

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30. Single-cell regulatory landscape and disease vulnerability map of adult Macaque cortex

    Ying Lei, Mengnan Cheng, Zihao Li, Zhen-Kun Zhuang +45 more

    20201 citations Open access

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31. Abstract 1763A: Single-cell RNA-sequencing reveals the immune contexture of triple-negative breast cancer tumors

    S. Qiu, R. Hong, Zhen-Kun Zhuang, Shu-Sen Wang

    2018Tumor Biology1 citations

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32. Evolutionary Origins of Molecular Programs Underlying Brain Circuitry

    Zhi Huang, Shenglong Li, Zhen-Kun Zhuang, Duoyuan Chen +10 more

    2026bioRxiv0 citations Open access

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33. How Much MRI Preprocessing Is Enough? A Cost-Utility Study for Brain MRI Foundation Models

    Jiangshuan Pang, Wangyang Tang, Jing Yan, Zhixuan Cheng +4 more

    2026arXiv.org0 citations

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34. Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea

    Xinyue Hu, Yang Guo, Ze Zhang, Li-Yuan Wang +5 more

    2026Scientific Data0 citations Open access

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35. Spatial transcriptomics reveal developmental dynamics of the human cerebral cortex and striatum.

    Yun-Jia Zhang, You-Ning Lin, Xu-Nan Shen, Guang-Lin He +26 more

    2026Science China Life Sciences0 citations Open access

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36. Spatial Transcriptomics Reveal Developmental Dynamics of the Human Cerebral Cortex and Striatum

    Yun-Jia Zhang, You-Ning Lin, Xu-Nan Shen, Xue Xiao +26 more

    2025bioRxiv0 citations

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37. Single-Cell Multiomics Analysis Reveals Heterogeneous Cell States Linked to Metastatic Potential in Liver Cancer Cell Lines

    Shan-Shan Wang, Jiarui Xie, Xuan-Xuan Zou, Taotao Pan +13 more

    2021Social Science Research Network0 citations

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38. Abstract 6600: Rapid generation of TCR-engineered T lymphocytes by linking the single cell transcriptome to its corresponding T cell receptor in antigen specific T cells

    Linnan Zhu, Fei Wang, Qumiao Xu, Haixi Sun +5 more

    2020Immunology0 citations

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39. A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus

    Fei Wang, Qumiao Xu, Zhen-Kun Zhuang, Ziyi Li +6 more

    2020Cellular & Molecular Immunology0 citations Open access

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