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J. Valenzuela · SciRah

Researcher profile · Semantic Scholar

J. Valenzuela

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J. Valenzuela — researcher profile on SciRah

h-index: 66
Works: 272
Citations: 13K

Most-cited papers

Gut Microbes Egested During Bites of Infected Sand flies Augment Severity of Leishmaniasis Via Inflammasome-Derived IL-1β
R. Dey, Amritanshu B Joshi, F. Oliveira, Lais S. Pereira +16 more
2017Cell Host and Microbe182 citations Open access
Semantic Scholar
The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum
Patrick Kelly, S. Bahr, T. D. Serafim, N. Ajami +6 more
2017mBio148 citations Open access
Semantic Scholar
Sequential blood meals augment vector infectiousness by promoting Leishmania replication and triggering amplification of metacyclics via a novel retroleptomonad developmental stage
T. D. Serafim, I. Coutinho-Abreu, F. Oliveira, C. Meneses +2 more
2018Nature Microbiology126 citations Open access
Semantic Scholar
A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing
Wen-Wei Zhang, S. Karmakar, S. Gannavaram, R. Dey +24 more
2020Nature Communications106 citations Open access
Semantic Scholar
Leishmaniasis: the act of transmission.
T. D. Serafim, I. Coutinho-Abreu, R. Dey, R. Kissinger +3 more
2021Trends in Parasitology105 citations
Semantic Scholar
Mosquito Saliva: The Hope for a Universal Arbovirus Vaccine?
J. Manning, D. Morens, S. Kamhawi, J. Valenzuela +1 more
2018Journal of Infectious Diseases67 citations Open access
Semantic Scholar
Ticks, Ixodes scapularis, Feed Repeatedly on White-Footed Mice despite Strong Inflammatory Response: An Expanding Paradigm for Understanding Tick–Host Interactions
Jennifer M. Anderson, Ian N. Moore, Bianca M. Nagata, J. Ribeiro +2 more
2017Frontiers in Immunology57 citations Open access
Semantic Scholar
Antibody targeting of a specific region of Pfs47 blocks Plasmodium falciparum malaria transmission
Gaspar Canepa, Alvaro Molina-Cruz, Lampouguin Yenkoidiok-Douti, E. Calvo +7 more
2018npj Vaccines56 citations Open access
Semantic Scholar
Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens
A. Vigneron, M. O’Neill, B. Weiss, A. Savage +4 more
2020Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial
J. Manning, F. Oliveira, I. Coutinho-Abreu, S. Herbert +16 more
2020The Lancet50 citations Open access
Semantic Scholar
Mining a differential sialotranscriptome of Rhipicephalus microplus guides antigen discovery to formulate a vaccine that reduces tick infestations
S. Maruyama, G. Garcia, F. R. Teixeira, L. G. Brandão +11 more
2017Parasites & Vectors47 citations Open access
Semantic Scholar
Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis
Pedro Cecílio, B. Pérez‐Cabezas, Laura Fernández, J. Moreno +12 more
2017PLoS Neglected Tropical Diseases47 citations Open access
Semantic Scholar
Understanding pathogen survival and transmission by arthropod vectors to prevent human disease
Carolina Barillas-Mury, J. Ribeiro, J. Valenzuela
2022Science45 citations
Semantic Scholar
Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection
Adela S. Oliva Chávez, Xiaowei Wang, L. Marnin, N. Archer +29 more
2021Nature Communications45 citations Open access
Semantic Scholar
A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden
B. Roatt, Rodrigo Dian de Oliveira Aguiar-Soares, L. E. S. Reis, Jamille Mirelle de Oliveira Cardoso +9 more
2017Frontiers in Immunology45 citations Open access
Semantic Scholar
Preclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis
S. Karmakar, Nevien Ismail, F. Oliveira, James Oristian +24 more
2021Communications Biology44 citations Open access
Semantic Scholar
SALO, a novel classical pathway complement inhibitor from saliva of the sand fly Lutzomyia longipalpis
V. Ferreira, Vladimir Fazito Vale, M. K. Pangburn, Maha Abdeladhim +15 more
2016Scientific Reports43 citations Open access
Semantic Scholar
Evaluation of cutaneous immune response in a controlled human in vivo model of mosquito bites
David Guerrero, H. T. M. Vo, C. Lon, J. Bohl +16 more
2022Nature Communications35 citations Open access
Semantic Scholar
Tick immunity using mRNA, DNA and protein-based Salp14 delivery strategies
Jaqueline Matias, C. Kurokawa, Andaleeb Sajid, S. Narasimhan +8 more
2021Vaccine32 citations Open access
Semantic Scholar
Circulating Biomarkers of Immune Activation, Oxidative Stress and Inflammation Characterize Severe Canine Visceral Leishmaniasis
M. S. Solca, B. Andrade, M. Abbehusen, C. Teixeira +8 more
2016Scientific Reports32 citations Open access
Semantic Scholar
Immunity to LuloHya and Lundep, the salivary spreading factors from Lutzomyia longipalpis, protects against Leishmania major infection
Inés Martín-Martín, A. Chagas, Anderson B. Guimarães-Costa, L. Amo +8 more
2018PLoS Pathogens31 citations Open access
Semantic Scholar
A sand fly salivary protein acts as a neutrophil chemoattractant
Anderson B. Guimarães-Costa, J. Shannon, Ingrid Waclawiak, Jullyanna Oliveira +10 more
2021Nature Communications30 citations Open access
Semantic Scholar
RNA-seq analysis of the salivary glands and midgut of the Argasid tick Ornithodoros rostratus
R. Araujo, N. Silva, A. Mendes-Sousa, R. Paim +10 more
2019Scientific Reports30 citations Open access
Semantic Scholar
Properdin-mediated C5a production enhances stable binding of platelets to granulocytes in human whole blood
Adam Z. Blatt, G. Saggu, Koustubh V. Kulkarni, Claudio Cortés +5 more
2016Journal of Immunology30 citations Open access
Semantic Scholar
Non-infectious environmental antigens as a trigger for the initiation of an autoimmune skin disease
Y. Qian, D. Culton, Joseph S. Y. Jeong, Nicole E. Trupiano +2 more
2016Autoimmunity Reviews27 citations Open access
Semantic Scholar
Overlapping IgG4 responses to self and environmental antigens in endemic pemphigus foliaceus
Y. Qian, Joseph S. Y. Jeong, Jian Ye, B. Dang +6 more
2016Journal of Immunology26 citations Open access
Semantic Scholar
Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers
I. Coutinho-Abreu, T. D. Serafim, C. Meneses, S. Kamhawi +2 more
2019bioRxiv25 citations Open access
Semantic Scholar
DNA plasmid coding for Phlebotomus sergenti salivary protein PsSP9, a member of the SP15 family of proteins, protects against Leishmania tropica
E. Gholami, F. Oliveira, T. Taheri, N. Seyed +15 more
2019PLoS Neglected Tropical Diseases25 citations Open access
Semantic Scholar
Prevalence of Cutaneous Leishmaniasis in Districts of High and Low Endemicity in Mali
Bourama Traore, F. Oliveira, O. Faye, A. Dicko +13 more
2016PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
Functional and structural similarities of D7 proteins in the independently-evolved salivary secretions of sand flies and mosquitoes
W. Jablonka, Il-Hwan Kim, P. Alvarenga, J. Valenzuela +2 more
2019Scientific Reports23 citations Open access
Semantic Scholar
Impact of vector biology research on old and emerging neglected tropical diseases
J. Valenzuela, S. Aksoy
2018PLoS Neglected Tropical Diseases22 citations Open access
Semantic Scholar
Safety and immunogenicity of AGS-v PLUS, a mosquito saliva peptide vaccine against arboviral diseases: A randomized, double-blind, placebo-controlled Phase 1 trial
D. Friedman-Klabanoff, M. Birkhold, Mara Short, Timothy R. Wilson +11 more
2022EBioMedicine21 citations Open access
Semantic Scholar
Amblyomma sculptum Salivary Protease Inhibitors as Potential Anti-Tick Vaccines
G. C. Costa, I. C. Ribeiro, Otoni Melo-Junior, N. F. Gontijo +10 more
2021Frontiers in Immunology21 citations Open access
Semantic Scholar
Heme Oxygenase-1 Induction by Blood-Feeding Arthropods Controls Skin Inflammation and Promotes Disease Tolerance.
Thiago DeSouza-Vieira, E. Iniguez, T. D. Serafim, Waldionê de Castro +16 more
2020Cell Reports21 citations Open access
Semantic Scholar
The Sand Fly Salivary Protein Lufaxin Inhibits the Early Steps of the Alternative Pathway of Complement by Direct Binding to the Proconvertase C3b-B
A. Mendes-Sousa, Vladimir Fazito Do Vale, N. Silva, Anderson B. Guimarães-Costa +8 more
2017Frontiers in Immunology21 citations Open access
Semantic Scholar
Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle
Pedro Cecílio, James Oristian, C. Meneses, T. D. Serafim +3 more
2020Scientific Reports20 citations Open access
Semantic Scholar
Exploring Lutzomyia longipalpis sand flies vector competence to Leishmania major parasites.
Pedro Cecílio, A. A. Pires, J. Valenzuela, P. Pimenta +3 more
2020Journal of Infectious Diseases20 citations Open access
Semantic Scholar
Leishmania infection induces a limited differential gene expression in the sand fly midgut
I. Coutinho-Abreu, T. D. Serafim, C. Meneses, S. Kamhawi +2 more
2019BMC Genomics20 citations Open access
Semantic Scholar
The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector
T. J. Bourret, William K. Boyle, Amanda K. Zalud, J. Valenzuela +2 more
2019Cellular Microbiology20 citations Open access
Semantic Scholar
Immunization of Experimental Dogs With Salivary Proteins From Lutzomyia longipalpis, Using DNA and Recombinant Canarypox Virus Induces Immune Responses Consistent With Protection Against Leishmania infantum
M. Abbehusen, J. Cunha, M. Suarez, C. Teixeira +13 more
2018Frontiers in Immunology20 citations Open access
Semantic Scholar
Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis
S. Karmakar, Greta Volpedo, Wen-Wei Zhang, Patrick Lypaczewski +12 more
2022bioRxiv19 citations Open access
Semantic Scholar
Comparative Evolution of Sand Fly Salivary Protein Families and Implications for Biomarkers of Vector Exposure and Salivary Vaccine Candidates
I. Coutinho-Abreu, J. Valenzuela
2018Frontiers in Cellular and Infection Microbiology19 citations Open access
Semantic Scholar
Immunization with LJM11 salivary protein protects against infection with Leishmania braziliensis in the presence of Lutzomyia longipalpis saliva
J. Cunha, M. Abbehusen, M. Suarez, J. Valenzuela +2 more
2017Acta Tropica19 citations Open access
Semantic Scholar
Protective Efficacy in a Hamster Model of a Multivalent Vaccine for Human Visceral Leishmaniasis (MuLeVaClin) Consisting of the KMP11, LEISH-F3+, and LJL143 Antigens in Virosomes, Plus GLA-SE Adjuvant
Laura Fernández, J. Solana, C. Sánchez, Mͣ Angeles Jimenez +16 more
2021Microorganisms18 citations Open access
Semantic Scholar
Towards a Sustainable Vector-Control Strategy in the Post Kala-Azar Elimination Era
R. Garlapati, E. Iniguez, T. D. Serafim, P. Mishra +6 more
2021Frontiers in Cellular and Infection Microbiology18 citations Open access
Semantic Scholar
Current vector research challenges in the greater Mekong subregion for dengue, Malaria, and Other Vector-Borne Diseases: A report from a multisectoral workshop March 2019
R. Christofferson, D. Parker, H. Overgaard, J. Hii +13 more
2020PLoS Neglected Tropical Diseases17 citations Open access
Semantic Scholar
Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites
Nívea F. Luz, Thiago DeSouza-Vieira, Waldionê de Castro, Á. C. Vivarini +15 more
2018Frontiers in Immunology17 citations Open access
Semantic Scholar
Seroconversion to Lutzomyia intermedia LinB-13 as a biomarker for developing cutaneous leishmaniasis
A. Carvalho, K. Fukutani, Rohit Sharma, Rebecca P. Curvelo +6 more
2017Scientific Reports16 citations Open access
Semantic Scholar
Phlebotomus papatasi Yellow-Related and Apyrase Salivary Proteins Are Candidates for Vaccination against Human Cutaneous Leishmaniasis
Aymen Tlili, S. Marzouki, Emna Chabaane, Maha Abdeladhim +8 more
2017Journal of Investigative Dermatology16 citations Open access
Semantic Scholar
Inhibition of the complement system by saliva of Anopheles (Nyssorhynchus) aquasalis
A. Mendes-Sousa, V. F. Vale, D. C. Queiroz, Adalberto Alves Pereira-Filho +9 more
2017Insect Biochemistry and Molecular Biology16 citations Open access
Semantic Scholar

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