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S. Mead · SciRah

Researcher profile · Semantic Scholar

S. Mead

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S. Mead — researcher profile on SciRah

h-index: 48
Works: 175
Citations: 7,640

Most-cited papers

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
Z. Jaunmuktane, S. Mead, M. Ellis, J. Wadsworth +9 more
2015Nature486 citations Open access
Semantic Scholar
Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease
P. Hermann, B. Appleby, J. Brandel, B. Caughey +15 more
2021Lancet Neurology273 citations Open access
Semantic Scholar
A naturally occurring variant of the human prion protein completely prevents prion disease
E. Asante, Michelle Smidak, Andrew Grimshaw, Richard Houghton +12 more
2015Nature178 citations Open access
Semantic Scholar
Variant Creutzfeldt-Jakob Disease in a Patient with Heterozygosity at PRNP Codon 129.
T. Mok, Z. Jaunmuktane, S. Joiner, T. Campbell +9 more
2017New England Journal of Medicine131 citations Open access
Semantic Scholar
CJD mimics and chameleons
S. Mead, P. Rudge
2017Practical Neurology105 citations Open access
Semantic Scholar
Evidence of amyloid-β cerebral amyloid angiopathy transmission through neurosurgery
Z. Jaunmuktane, A. Quaegebeur, R. Taipa, M. Viana-Baptista +5 more
2018Acta Neuropathologica103 citations Open access
Semantic Scholar
Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years
P. Rudge, Z. Jaunmuktane, P. Adlard, N. Bjurstrom +10 more
2015Brain : a journal of neurology103 citations Open access
Semantic Scholar
Iatrogenic cerebral amyloid angiopathy: an emerging clinical phenomenon
G. Banerjee, Kiran Samra, M. Adams, Z. Jaunmuktane +12 more
2022Journal of Neurology Neurosurgery & Psychiatry102 citations Open access
Semantic Scholar
Iatrogenic Alzheimer’s disease in recipients of cadaveric pituitary-derived growth hormone
G. Banerjee, Simon F. Farmer, H. Hyare, Z. Jaunmuktane +6 more
2024Nature Medicine90 citations Open access
Semantic Scholar
Imaging and CSF analyses effectively distinguish CJD from its mimics
P. Rudge, H. Hyare, A. Green, J. Collinge +1 more
2017Journal of Neurology Neurosurgery & Psychiatry90 citations Open access
Semantic Scholar
Genetic Factors in Mammalian Prion Diseases.
S. Mead, S. Lloyd, J. Collinge
2019Annual Review of Genetics88 citations
Semantic Scholar
Early onset cerebral amyloid angiopathy following childhood exposure to cadaveric dura
G. Banerjee, M. Adams, Z. Jaunmuktane, G. Lammie +7 more
2019Annals of Neurology82 citations Open access
Semantic Scholar
Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt-Jakob disease: evaluation of a first-in-human treatment programme.
S. Mead, A. Khalili-Shirazi, C. Potter, T. Mok +17 more
2022Lancet Neurology78 citations Open access
Semantic Scholar
Diffusion-weighted MRI signal abnormality in sporadic CJD increases in extent and intensity with disease duration
Laura B. Eisenmenger, Marie-Claire Porter, C. Carswell, A. Thompson +6 more
2016JAMA Neurology67 citations Open access
Semantic Scholar
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
E. Jones, H. Hummerich, Emmanuelle Viré, J. Uphill +61 more
2020Lancet Neurology59 citations Open access
Semantic Scholar
Potential human transmission of amyloid β pathology: surveillance and risks.
Elsa Lauwers, G. Lalli, S. Brandner, J. Collinge +33 more
2020Lancet Neurology56 citations Open access
Semantic Scholar
Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases
A. Thompson, Prodromos Anastasiadis, R. Druyeh, Ines Whitworth +12 more
2020Molecular Psychiatry54 citations Open access
Semantic Scholar
Rare coding variants in PLCG 2 , ABI 3 , and TREM 2 implicate microglial-mediated innate immunity in Alzheimer ' s disease
Joseph E. Parisi, Henry L. Paulson, William R. Perry, E. Peskind +172 more
201953 citations
Semantic Scholar
Clinical considerations in early-onset cerebral amyloid angiopathy
G. Banerjee, J. Collinge, Nick C Fox, T. Lashley +4 more
2023Brain : a journal of neurology48 citations Open access
Semantic Scholar
Recent US Case of Variant Creutzfeldt-Jakob Disease—Global Implications
A. Maheshwari, M. Fischer, P. Gambetti, Alicia Parker +11 more
2015Emerging Infectious Diseases43 citations Open access
Semantic Scholar
Prevalence in Britain of abnormal prion protein in human appendices before and after exposure to the cattle BSE epizootic
O. Gill, Y. Spencer, A. Richard-Loendt, C. Kelly +15 more
2020Acta Neuropathologica40 citations Open access
Semantic Scholar
Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease
T. Mok, Akın Nihat, N. Majbour, Danielle Sequeira +29 more
2023Brain : a journal of neurology39 citations Open access
Semantic Scholar
Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease
S. Mead, M. Burnell, J. Lowe, A. Thompson +17 more
2016JAMA Neurology39 citations Open access
Semantic Scholar
A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis
P. Norsworthy, A. Thompson, T. Mok, Fernando Guntoro +7 more
2020Nature Communications29 citations Open access
Semantic Scholar
Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases
T. Mok, Akın Nihat, Connie Luk, Danielle Sequeira +4 more
2021Scientific Reports28 citations Open access
Semantic Scholar
Alzheimer’s disease neuropathological change three decades after iatrogenic amyloid-β transmission
Z. Jaunmuktane, G. Banerjee, S. Paine, A. Parry-Jones +8 more
2021Acta Neuropathologica27 citations Open access
Semantic Scholar
Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt–Jakob disease
L. Dabin, Fernando Guntoro, T. Campbell, Tony Bélicard +9 more
2020Acta Neuropathologica27 citations Open access
Semantic Scholar
Quantitative EEG parameters correlate with the progression of human prion diseases
E. Frankó, T. Wehner, O. Joly, J. Lowe +6 more
2016Journal of Neurology Neurosurgery & Psychiatry27 citations Open access
Semantic Scholar
Prospective diagnosis of sporadic CJD by the detection of abnormal PrP in patient urine
Connie Luk, Samantha Jones, Claire Thomas, Nick C Fox +4 more
2016JAMA Neurology27 citations Open access
Semantic Scholar
Predictive Testing for Inherited Prion Disease - report of 22 years experience
Jane Owen, J. Beck, T. Campbell, G. Adamson +7 more
2014European Journal of Human Genetics25 citations Open access
Semantic Scholar
The cognitive profile of prion disease: a prospective clinical and imaging study
D. Caine, Renata J Tinelli, H. Hyare, E. De Vita +8 more
2015Annals of Clinical and Translational Neurology24 citations Open access
Semantic Scholar
Assessing initial MRI reports for suspected CJD patients
Aaron Jesuthasan, Danielle Sequeira, H. Hyare, Hans Odd +5 more
2022Journal of Neurology19 citations Open access
Semantic Scholar
Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS
E. Asante, J. Linehan, Andrew Tomlinson, T. Jakubcova +9 more
2020PLoS Biology18 citations Open access
Semantic Scholar
Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease
P. Rudge, Z. Jaunmuktane, H. Hyare, M. Ellis +4 more
2019Brain : a journal of neurology16 citations Open access
Semantic Scholar
Methods for Molecular Diagnosis of Human Prion Disease.
J. Wadsworth, G. Adamson, S. Joiner, Lara Brock +6 more
2017Methods in molecular biology15 citations
Semantic Scholar
Prevalence and Treatments of Movement Disorders in Prion Diseases: A Longitudinal Cohort Study
Danielle Sequeira, Akın Nihat, T. Mok, Thomas Coysh +3 more
2022Movement Disorders14 citations Open access
Semantic Scholar
Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference
D. Heinzer, Merve Avar, D. Pease, A. Dhingra +11 more
2021bioRxiv14 citations Open access
Semantic Scholar
Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6
Emma Jones, Elizabeth Hill, J. Linehan, Tamsin Nazari +15 more
2023Neurobiology of Disease13 citations Open access
Semantic Scholar
The most problematic symptoms of prion disease – an analysis of carer experiences
L. Ford, P. Rudge, Kathy Robinson, J. Collinge +2 more
2018International Psychogeriatrics12 citations Open access
Semantic Scholar
The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature
D. Caine, Akın Nihat, Philippa Crabb, P. Rudge +3 more
2018PLoS ONE12 citations Open access
Semantic Scholar
Development of prognostic models for survival and care status in sporadic Creutzfeldt-Jakob disease
Akın Nihat, J. Ranson, D. Harris, Kirsty McNiven +5 more
2022medRxiv11 citations Open access
Semantic Scholar
Erratum: Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
Z. Jaunmuktane, S. Mead, M. Ellis, J. Wadsworth +9 more
2015Nature11 citations Open access
Semantic Scholar
Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes
F. Küçükali, Elizabeth Hill, T. Watzeels, H. Hummerich +39 more
2024medRxiv10 citations Open access
Semantic Scholar
Gene expression and epigenetic markers of prion diseases
Emmanuelle Viré, S. Mead
2022Cell and Tissue Research10 citations Open access
Semantic Scholar
Syntaxin-6 delays prion protein fibril formation and prolongs the presence of toxic aggregation intermediates
D. Sangar, Elizabeth Hill, Kezia Jack, M. Batchelor +5 more
2023bioRxiv9 citations Open access
Semantic Scholar
Prion protein gene mutation detection using long-read Nanopore sequencing
François Kroll, A. Dimitriadis, T. Campbell, Lee Darwent +3 more
2022Scientific Reports9 citations Open access
Semantic Scholar
NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression
David Mengel, T. Mok, Akın Nihat, Wen Liu +6 more
2021Cells9 citations Open access
Semantic Scholar
Development of novel clinical examination scales for the measurement of disease severity in Creutzfeldt-Jakob disease
Akın Nihat, T. Mok, Hans Odd, A. Thompson +7 more
2020Journal of Neurology Neurosurgery & Psychiatry9 citations Open access
Semantic Scholar
Enteral feeding is associated with longer survival in the advanced stages of prion disease
Kirsty McNiven, Akın Nihat, T. Mok, Selam Tesfamichael +4 more
2019Brain Communications9 citations Open access
Semantic Scholar
Familial Creutzfeldt-Jakob Disease in an Indian Kindred
S. Katrak, A. Pauranik, S. Desai, S. Mead +3 more
2019Annals of Indian Academy of Neurology9 citations Open access
Semantic Scholar

Frequent co-authors

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J. Collinge×36
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P. Rudge×24
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S. Brandner×18
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Z. Jaunmuktane×14
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Z. Jaunmuktane — researcher profile on SciRah

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T. Mok — researcher profile on SciRah

Akın Nihat×14

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J. Wadsworth×9

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J. Wadsworth — researcher profile on SciRah

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J. Linehan — researcher profile on SciRah

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H. Hyare — researcher profile on SciRah

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A. Thompson — researcher profile on SciRah

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T. Campbell — researcher profile on SciRah

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J. Schott — researcher profile on SciRah