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K. Fröhlich · SciRah

Researcher profile · Semantic Scholar

K. Fröhlich

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K. Fröhlich — researcher profile on SciRah

h-index: 39
Works: 65
Citations: 12K

Most-cited papers

Induction of autophagy by spermidine promotes longevity
T. Eisenberg, H. Knauer, Alexandra Schauer, S. Büttner +25 more
2009Nature Cell Biology1,654 citations Open access
Semantic Scholar
Oxygen Stress: A Regulator of Apoptosis in Yeast
F. Madeo, E. Fröhlich, M. Ligr, Martin Grey +3 more
1999Journal of Cell Biology1,058 citations Open access
Semantic Scholar
A caspase-related protease regulates apoptosis in yeast.
F. Madeo, E. Herker, Corinna Maldener, S. Wissing +7 more
2002Molecules and Cells911 citations Open access
Semantic Scholar
A Yeast Mutant Showing Diagnostic Markers of Early and Late Apoptosis
F. Madeo, E. Fröhlich, K. Fröhlich
1997Journal of Cell Biology816 citations Open access
Semantic Scholar
Chronological aging leads to apoptosis in yeast
E. Herker, H. Jungwirth, Katharina A. Lehmann, Corinna Maldener +6 more
2004Journal of Cell Biology570 citations Open access
Semantic Scholar
AAA-ATPase p97/Cdc48p, a Cytosolic Chaperone Required for Endoplasmic Reticulum-Associated Protein Degradation
E. Rabinovich, A. Kerem, K. Fröhlich, Noam Diamant +1 more
2002Molecular and Cellular Biology570 citations Open access
Semantic Scholar
Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis
P. Laun, A. Pichová, F. Madeo, J. Fuchs +5 more
2001Molecular Microbiology441 citations Open access
Semantic Scholar
An AIF orthologue regulates apoptosis in yeast
S. Wissing, P. Ludovico, E. Herker, S. Büttner +12 more
2004Journal of Cell Biology408 citations Open access
Semantic Scholar
Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes.
M. Latterich, K. Fröhlich, R. Schekman
1995Cell394 citations Open access
Semantic Scholar
Endonuclease G regulates budding yeast life and death.
S. Büttner, T. Eisenberg, D. Carmona-Gutierrez, D. Ruli +8 more
2007Molecules and Cells339 citations Open access
Semantic Scholar
PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases.
R. Erdmann, F. Wiebel, Arne Flessau, J. Rytka +3 more
1991Cell328 citations
Semantic Scholar
Apoptosis in yeast.
F. Madeo, E. Herker, S. Wissing, H. Jungwirth +2 more
2004Current Opinion in Microbiology323 citations
Semantic Scholar
Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression
K. Fröhlich, H. Fries, M. Rüdiger, R. Erdmann +2 more
1991Journal of Cell Biology296 citations Open access
Semantic Scholar
Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan
T. Eisenberg, Sabrina Schroeder, A. Andryushkova, T. Pendl +29 more
2014Cell Metabolism261 citations Open access
Semantic Scholar
Apoptosis in yeast – a monocellular organism exhibits altruistic behaviour
K. Fröhlich, F. Madeo
2000FEBS Letters232 citations
Semantic Scholar
Apoptosis in yeast: a new model system with applications in cell biology and medicine
F. Madeo, S. Engelhardt, E. Herker, Nina Lehmann +4 more
2002Current Genetics218 citations
Semantic Scholar
Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification
C. Ruckenstuhl, C. Netzberger, Iryna Entfellner, D. Carmona-Gutierrez +14 more
2014PLoS Genetics214 citations Open access
Semantic Scholar
Mammalian Bax triggers apoptotic changes in yeast
M. Ligr, F. Madeo, E. Fröhlich, W. Hilt +2 more
1998FEBS Letters210 citations Open access
Semantic Scholar
Guidelines and recommendations on yeast cell death nomenclature
D. Carmona-Gutierrez, Maria A. Bauer, Andreas Zimmermann, A. Aguilera +83 more
2018Microbial Cell181 citations Open access
Semantic Scholar
Tyrosine phosphorylation regulates cell cycle-dependent nuclear localization of Cdc48p.
F. Madeo, J. Schlauer, H. Zischka, D. Mecke +1 more
1998Molecular Biology of the Cell149 citations Open access
Semantic Scholar
Saccharomyces cerevisiae mutants provide evidence of hexokinase PII as a bifunctional enzyme with catalytic and regulatory domains for triggering carbon catabolite repression
K. Entian, K. Fröhlich
1984Journal of Bacteriology131 citations Open access
Semantic Scholar
A yeast BH3‐only protein mediates the mitochondrial pathway of apoptosis
S. Büttner, D. Ruli, F. Vögtle, L. Galluzzi +14 more
2011EMBO Journal128 citations Open access
Semantic Scholar
The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer
C. Ruckenstuhl, S. Büttner, D. Carmona-Gutierrez, T. Eisenberg +4 more
2009PLoS ONE115 citations Open access
Semantic Scholar
Defects in N‐glycosylation induce apoptosis in yeast
P. Hauptmann, C. Riel, L. Kunz-Schughart, K. Fröhlich +2 more
2006Molecular Microbiology104 citations Open access
Semantic Scholar
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson’s disease
S. Büttner, L. Habernig, F. Broeskamp, D. Ruli +25 more
2013EMBO Journal89 citations Open access
Semantic Scholar
The proteasomal substrate Stm1 participates in apoptosis-like cell death in yeast.
M. Ligr, I. Velten, E. Fröhlich, F. Madeo +4 more
2001Molecular Biology of the Cell86 citations Open access
Semantic Scholar
Metacaspases are caspases. Doubt no more
D. Carmona-Gutierrez, K. Fröhlich, G. Kroemer, F. Madeo
2010Cell Death and Differentiation83 citations Open access
Semantic Scholar
Yeast apoptosis--from genes to pathways.
K. Fröhlich, Heike Fussi, C. Ruckenstuhl
2007Seminars in Cancer Biology83 citations
Semantic Scholar
Starvation for an essential amino acid induces apoptosis and oxidative stress in yeast.
Herfried Eisler, K. Fröhlich, Erich Heidenreich
2004Experimental Cell Research73 citations
Semantic Scholar
The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression.
K. Fröhlich, K. Entian, D. Mecke
1985Gene73 citations
Semantic Scholar
The propeptide of yeast cathepsin D inhibits programmed necrosis
D. Carmona-Gutierrez, Maria A. Bauer, J. Ring, H. Knauer +12 more
2011Cell Death and Disease71 citations Open access
Semantic Scholar
Molecular recognition determinants for type IV secretion of diverse families of conjugative relaxases
Silvia Lang, K. Gruber, Sanja Mihajlovic, R. Arnold +6 more
2010Molecular Microbiology70 citations Open access
Semantic Scholar
Comment on Severin, F.F., and Hyman, A.A. (2002). Pheromone induces programmed cell death in S. cerevisiae. Curr. Biol. 12, R233-R235.
F. Madeo, K. Fröhlich
2002Current Biology68 citations Open access
Semantic Scholar
The ATPase activity of purified CDC48p from Saccharomyces cerevisiae shows complex dependence on ATP-, ADP-, and NADH-concentrations and is completely inhibited by NEM.
K. Fröhlich, H. Fries, Jan-Michael Peters, D. Mecke
1995Biochimica et Biophysica Acta59 citations
Semantic Scholar
Identification of evolutionarily conserved genetic regulators of cellular aging
G. Laschober, D. Ruli, Edith Hofer, Christoph Muck +24 more
2010Aging Cell58 citations Open access
Semantic Scholar
An AAA family tree.
K. Fröhlich
2001Journal of Cell Science57 citations
Semantic Scholar
Pichia pastoris "just in time" alternative respiration.
Alexander Kern, F. Hartner, M. Freigaßner, Julia Spielhofer +4 more
2007Microbiology53 citations Open access
Semantic Scholar
Apoptosis in yeast: a new model for aging research.
K. Fröhlich, F. Madeo
2001Experimental Gerontology51 citations
Semantic Scholar
Induction of apoptosis in yeast by L‐amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma
Sudharsana Rao Ande, Heike Fussi, H. Knauer, M. Murkovic +3 more
2008Yeast50 citations
Semantic Scholar
Ceramide triggers metacaspase-independent mitochondrial cell death in yeast
D. Carmona-Gutierrez, A. Reisenbichler, Petra Heimbucher, Maria A. Bauer +8 more
2011Cell Cycle37 citations Open access
Semantic Scholar
Regulation of enzymes and isoenzymes of carbohydrate metabolism in the yeast Saccharomyces cerevisiae.
K. Entian, K. Fröhlich, D. Mecke
1984Biochimica et Biophysica Acta36 citations
Semantic Scholar
Vacuolar functions determine the mode of cell death.
Alexandra Schauer, H. Knauer, C. Ruckenstuhl, Heike Fussi +3 more
2009Biochimica et Biophysica Acta35 citations Open access
Semantic Scholar
Alcohol Enhances Oxysterol-Induced Apoptosis in Human Endothelial Cells by a Calcium-Dependent Mechanism
I. Spyridopoulos, J. Wischhusen, B. Rabenstein, Petra Mayer +3 more
2001Arteriosclerosis, Thrombosis and Vascular Biology35 citations Open access
Semantic Scholar
Acetyl-CoA carboxylase 1–dependent lipogenesis promotes autophagy downstream of AMPK
A. Gross, Andreas Zimmermann, T. Pendl, Sabrina Schroeder +20 more
2019Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Spermidine promotes mating and fertilization efficiency in model organisms
Maria A. Bauer, D. Carmona-Gutierrez, C. Ruckenstuhl, A. Reisenbichler +10 more
2013Cell Cycle33 citations Open access
Semantic Scholar
Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals
F. Madeo, M. Durchschlag, O. Kepp, T. Panaretakis +3 more
2009Cell Cycle28 citations Open access
Semantic Scholar
Substitution of a pentalenolactone-sensitive glyceraldehyde-3-phosphate dehydrogenase by a genetically distinct resistant isoform accompanies pentalenolactone production in Streptomyces arenae
K. Fröhlich, M. Wiedmann, F. Lottspeich, D. Mecke
1989Journal of Bacteriology26 citations Open access
Semantic Scholar
Yeast as a model for ageing and apoptosis research
M. Breitenbach, F. Madeo, P. Laun, G. Heeren +4 more
200323 citations
Semantic Scholar
Characterization of enzymes from Ancistrocladus (Ancistrocladaceae) and Triphyophyllum (Dioncophyllaceae) catalyzing oxidative coupling of naphthylisoquinoline alkaloids to michellamines.
J. Schlauer, M. Rückert, B. Wiesen, M. Herderich +5 more
1998Archives of Biochemistry and Biophysics22 citations
Semantic Scholar
Identification of the regions of porcine VCP preventing its function in Saccharomyces cerevisiae.
F. Madeo, Jan Schlauer, K. Fröhlich
1997Gene22 citations
Semantic Scholar

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D. Carmona-Gutierrez×14
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S. Wissing — researcher profile on SciRah

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