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I. Spyridopoulos · SciRah

Researcher profile · Semantic Scholar

I. Spyridopoulos

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I. Spyridopoulos — researcher profile on SciRah

h-index: 42
Works: 246
Citations: 7,216

Most-cited papers

Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction
A. Walaszczyk, Emily Dookun, R. Redgrave, Simon Tual-Chalot +6 more
2019Aging Cell222 citations Open access
Semantic Scholar
Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery
Emily Dookun, A. Walaszczyk, R. Redgrave, P. Palmowski +16 more
2020Aging Cell155 citations Open access
Semantic Scholar
Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls
W. A. Owens, A. Walaszczyk, I. Spyridopoulos, Emily Dookun +1 more
2021Mechanisms of Ageing and Development98 citations Open access
Semantic Scholar
Cellular Senescence, Mitochondrial Dysfunction, and Their Link to Cardiovascular Disease
Maria Camacho-Encina, Laura K Booth, R. Redgrave, O. Folaranmi +2 more
2024Cells79 citations Open access
Semantic Scholar
Lymphocyte Communication in Myocardial Ischemia/Reperfusion Injury
Stephen E. Boag, Emanuele Andreano, I. Spyridopoulos
2017Antioxidants and Redox Signaling72 citations Open access
Semantic Scholar
Involvement of cardiovascular system as the critical point in coronavirus disease 2019 (COVID-19) prognosis and recovery
C. Lazaridis, N. Vlachogiannis, C. Bakogiannis, I. Spyridopoulos +4 more
2020Hellenic Journal of Cardiology57 citations Open access
Semantic Scholar
Roadmap for alleviating the manifestations of ageing in the cardiovascular system
L. Liberale, Simon Tual-Chalot, S. Sedej, S. Ministrini +57 more
2025Nature Reviews Cardiology54 citations Open access
Semantic Scholar
Telomerase As a Therapeutic Target in Cardiovascular Disease.
J. Hoffmann, G. Richardson, J. Haendeler, J. Altschmied +2 more
2021Arteriosclerosis, Thrombosis and Vascular Biology53 citations Open access
Semantic Scholar
Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction
R. Redgrave, Emily Dookun, Laura K Booth, Maria Camacho Encina +7 more
2023npj Aging50 citations Open access
Semantic Scholar
Modification of the GRACE Risk Score for Risk Prediction in Patients With Acute Coronary Syndromes.
G. Georgiopoulos, S. Kraler, M. Mueller-Hennessen, D. Delialis +25 more
2023JAMA cardiology47 citations Open access
Semantic Scholar
Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging
M. Delgobo, M. Heinrichs, Nils Hapke, D. Ashour +7 more
2021Frontiers in Immunology44 citations Open access
Semantic Scholar
Immobilization of Molecularly Imprinted Polymer Nanoparticles onto Surfaces Using Different Strategies: Evaluating the Influence of the Functionalized Interface on the Performance of a Thermal Assay for the Detection of the Cardiac Biomarker Troponin I.
J. McClements, Patrick Marcel Seumo Tchekwagep, Ana Luiza Vilela Strapazon, F. Canfarotta +10 more
2021ACS Applied Materials and Interfaces42 citations Open access
Semantic Scholar
CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians
C. Martin-Ruiz, J. Hoffmann, E. Shmeleva, T. von Zglinicki +7 more
2020npj Aging and Mechanisms of Disease39 citations Open access
Semantic Scholar
Inflammageing in the cardiovascular system: mechanisms, emerging targets, and novel therapeutic strategies.
Danlin Liu, G. Richardson, F. M. Benli, Catherine Park +3 more
2020Clinical science34 citations Open access
Semantic Scholar
CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system—New mode of action for caffeine
Niloofar Ale-Agha, C. Goy, P. Jakobs, I. Spyridopoulos +17 more
2018PLoS Biology30 citations Open access
Semantic Scholar
Effect of Pressure-controlled intermittent Coronary Sinus Occlusion (PiCSO) on infarct size in anterior STEMI: PiCSO in ACS study
M. Egred, A. Bagnall, I. Spyridopoulos, I. Purcell +8 more
2020International Journal of Cardiology: Heart & Vasculature29 citations Open access
Semantic Scholar
Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules.
C. Heiss, I. Spyridopoulos, J. Haendeler
2017Experimental Gerontology29 citations Open access
Semantic Scholar
Zibotentan in Microvascular Angina: A Randomized, Placebo-Controlled, Crossover Trial
A. Morrow, Robin Young, George R. Abraham, Stephen P. Hoole +26 more
2024Circulation27 citations Open access
Semantic Scholar
Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction
B. Bawamia, L. Spray, V. Wangsaputra, K. Bennaceur +11 more
2023GeroScience27 citations Open access
Semantic Scholar
Fractalkine Signalling (CX3CL1/CX3CR1 Axis) as an Emerging Target in Coronary Artery Disease
S. Loh, Y. Ekinci, L. Spray, Visvesh Jeyalan +5 more
2023Journal of Clinical Medicine26 citations Open access
Semantic Scholar
Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives
L. Spray, Gavin Richardson, Judith Haendeler, J. Altschmied +8 more
2025Cell Reports Medicine25 citations Open access
Semantic Scholar
Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells
G. Richardson, A. Sage, K. Bennaceur, Nayef Al Zhrany +7 more
2018Arteriosclerosis, Thrombosis and Vascular Biology24 citations Open access
Semantic Scholar
Microvascular Obstruction in Acute Myocardial Infarction, a Potential Therapeutic Target
M. Ghobrial, Bilal Bawamia, Timothy Cartlidge, I. Spyridopoulos +7 more
2023Journal of Clinical Medicine22 citations Open access
Semantic Scholar
The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation.
A. Gatsiou, Simon Tual-Chalot, Matteo Napoli, A. Ortega-Gómez +34 more
2023Immunity21 citations Open access
Semantic Scholar
Cathepsin S Levels and Survival Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.
K. Stamatelopoulos, M. Mueller-Hennessen, G. Georgiopoulos, P. López-Ayala +20 more
2022Journal of the American College of Cardiology21 citations Open access
Semantic Scholar
The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling
L. Spray, Catherine Park, S. Cormack, Ashfaq Mohammed +12 more
2021Frontiers in Immunology21 citations Open access
Semantic Scholar
Rapid fall in circulating non-classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury
Sarah A. Marsh, Catherine Park, R. Redgrave, E. Singh +6 more
2021bioRxiv19 citations Open access
Semantic Scholar
Clinical frailty, and not features of acute infection, is associated with late mortality in COVID‐19: a retrospective cohort study
N. Vlachogiannis, K. Baker, G. Georgiopoulos, C. Lazaridis +9 more
2022Journal of Cachexia, Sarcopenia and Muscle17 citations Open access
Semantic Scholar
Telomerase Activation to Reverse Immunosenescence in Elderly Patients With Acute Coronary Syndrome: Protocol for a Randomized Pilot Trial
R. Maier, B. Bawamia, K. Bennaceur, Sarah Dunn +7 more
2020JMIR Research Protocols17 citations Open access
Semantic Scholar
Effect of ciclosporin on safety, lymphocyte kinetics and left ventricular remodelling in acute myocardial infarction
S. Cormack, Ashfaq Mohammed, P. Panahi, R. Das +6 more
2020British Journal of Clinical Pharmacology17 citations Open access
Semantic Scholar
Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction
J. Coelho-Lima, Ashfaq Mohammed, S. Cormack, Samuel Jones +5 more
2018Thrombosis and Haemostasis17 citations Open access
Semantic Scholar
Heart Disease and Ageing: The Roles of Senescence, Mitochondria, and Telomerase in Cardiovascular Disease.
Laura K Booth, R. Redgrave, Simon Tual-Chalot, I. Spyridopoulos +2 more
2023Sub-cellular biochemistry16 citations
Semantic Scholar
Exercise, telomerase activity, and cardiovascular disease prevention
K. Stellos, I. Spyridopoulos
2018European Heart Journal16 citations Open access
Semantic Scholar
Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study.
A. Granic, C. Martin-Ruiz, R. Dodds, L. Robinson +4 more
2020Mechanisms of Ageing and Development14 citations Open access
Semantic Scholar
Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion.
J. Coelho-Lima, Ashfaq Mohammed, S. Cormack, Samuel Jones +7 more
2019Clinical Chemistry14 citations Open access
Semantic Scholar
Troponin I biomarker sensing from clinical patient samples using molecularly imprinted polymer nanoparticles for advancing healthcare approaches in cardiovascular disease.
J. Saczek, O. Jamieson, J. McClements, A. Dann +10 more
2025Biosensors & bioelectronics13 citations Open access
Semantic Scholar
Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction
R. Redgrave, Emily Dookun, Laura K Booth, Omowumi Folaranm +6 more
2023Research Square13 citations Open access
Semantic Scholar
Clinical outcomes of coronary intravascular lithotripsy in patients with stent failure (COIL registry).
M. Kuzemczak, J. Lipiecki, Visvesh Jeyalan, Hicham Farhat +13 more
2023International Journal of Cardiology13 citations Open access
Semantic Scholar
A comparative analysis of British and American Society of Echocardiography recommendations for the assessment of left ventricular diastolic function
P. Luke, Christopher J. Eggett, I. Spyridopoulos, T. Irvine
2018Echo Research and Practice13 citations Open access
Semantic Scholar
Defining an ageing-related pathology, disease or syndrome: International Consensus Statement
Emma L Short, I. Adcock, B. Al-Sarireh, Ann Ager +223 more
2024GeroScience12 citations Open access
Semantic Scholar
Exogenous Transforming Growth Factor-β1 and Its Helminth-Derived Mimic Attenuate the Heart's Inflammatory Response to Ischemic Injury and Reduce Mature Scar Size
R. Redgrave, E. Singh, Simon Tual-Chalot, Catherine Park +6 more
2023American Journal of Pathology12 citations Open access
Semantic Scholar
The role of arginine vasopressin in myocardial infarction and reperfusion.
Andre Nobian, Mohamed Ashfaq, I. Spyridopoulos
2019Kardiologia polska12 citations Open access
Semantic Scholar
How to measure and model cardiovascular aging
L. Spray, Gavin Richardson, Laura K Booth, Judith Haendeler +6 more
2025Cardiovascular Research10 citations Open access
Semantic Scholar
Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction
K. Sopova, Simon Tual-Chalot, M. Mueller-Hennessen, N. Vlachogiannis +19 more
2023Frontiers in Immunology9 citations Open access
Semantic Scholar
Prognostic value of admission high-sensitivity troponin in patients with ST-elevation myocardial infarction
J. Coelho-Lima, G. Georgiopoulos, J. Ahmed, Syeda Ezz-e-rukhshan Adil +11 more
2021Heart9 citations Open access
Semantic Scholar
Fractalkine/CX3CR1 in Dilated Cardiomyopathy: A Potential Future Target for Immunomodulatory Therapy?
Visvesh Jeyalan, D. Austin, Shu Xian Loh, V. Wangsaputra +1 more
2023Cells7 citations Open access
Semantic Scholar
Very early discharge after primary percutaneous coronary intervention for ST-elevation myocardial infarction: Mortality outcomes at six months.
Bilal Bawamia, Andrew Brown, I. Spyridopoulos, A. Bagnall +5 more
2022Cardiovascular Revascularization Medicine7 citations Open access
Semantic Scholar
Immunosenescence profiles of lymphocyte compartments and multiple long-term conditions (multimorbidity) in very old adults: The Newcastle 85+ Study.
A. Granic, C. Martin-Ruiz, L. Rimmer, R. Dodds +5 more
2022Mechanisms of Ageing and Development7 citations Open access
Semantic Scholar
Arginine Vasopressin Plays a Role in Microvascular Dysfunction After ST‐Elevation Myocardial Infarction
Ayman Al-atta, L. Spray, Ashfaq Mohammed, E. Shmeleva +1 more
2023Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease4 citations Open access
Semantic Scholar
Longer leukocyte telomere length is associated with myeloid inflammation and increased mortality after transcatheter aortic valve replacement
J. Hoffmann, N. Tabata, S. Mas-Peiro, I. Spyridopoulos +8 more
2022European Heart Journal Open4 citations Open access
Semantic Scholar

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