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Xin Cheng · SciRah

Researcher profile · Semantic Scholar

Xin Cheng

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Xin Cheng — researcher profile on SciRah

h-index: 23
Works: 92
Citations: 1,664

Most-cited papers

Targeting TNF: a therapeutic strategy for Alzheimer's disease.
Xin Cheng, Yong Shen, Re-Na Li
2014Drug Discovery Today120 citations
Semantic Scholar
Differential Activation of Tumor Necrosis Factor Receptors Distinguishes between Brains from Alzheimer’s Disease and Non-Demented Patients
Xin Cheng, Li-Bang Yang, P. He, Re-Na Li +1 more
2010Journal of Alzheimer's Disease100 citations Open access
Semantic Scholar
High activities of BACE1 in brains with mild cognitive impairment.
Xin Cheng, P. He, Taehee Lee, Hai-Lan Yao +2 more
2014American Journal of Pathology80 citations Open access
Semantic Scholar
Long-Term Treatment of Thalidomide Ameliorates Amyloid-Like Pathology through Inhibition of β-Secretase in a Mouse Model of Alzheimer’s Disease
P. He, Xin Cheng, M. Staufenbiel, Re-Na Li +1 more
2013PLoS ONE69 citations Open access
Semantic Scholar
Endothelial BACE1 Impairs Cerebral Small Vessels via Tight Junctions and eNOS
Haoyue Zhou, F. Gao, Xiaoli Yang, Ting-Ting Lin +14 more
2022Circulation Research64 citations Open access
Semantic Scholar
Increased CSF-BACE1 Activity Associated with Decreased Hippocampus Volume in Alzheimer's Disease
M. Ewers, Xin Cheng, Zhenyu Zhong, H. Nural +7 more
2011Journal of Alzheimer's Disease61 citations
Semantic Scholar
Glymphatic dysfunction correlates with severity of small vessel disease and cognitive impairment in cerebral amyloid angiopathy
Jia-Jie Xu, Ya Su, Jiayu Fu, Xiao-Xiao Wang +4 more
2022European Journal of Neurology60 citations
Semantic Scholar
The blood pressure paradox in acute ischemic stroke
L. Hong, Xin Cheng, Long-Ting Lin, A. Bivard +4 more
2019Annals of Neurology54 citations Open access
Semantic Scholar
Endovascular Thrombectomy Versus Medical Management in Isolated M2 Occlusions: Pooled Patient‐Level Analysis from the EXTEND‐IA Trials, INSPIRE, and SELECT Studies
A. Sarraj, M. Parsons, A. Bivard, A. Hassan +26 more
2022Annals of Neurology48 citations
Semantic Scholar
Decreased water exchange rate across blood–brain barrier in hereditary cerebral small vessel disease
Yingying Li, Yunqing Ying, T. Yao, Xue-Jia Jia +9 more
2023Brain : a journal of neurology47 citations Open access
Semantic Scholar
White matter hyperintensities associated with progression of cerebral small vessel disease: a 7-year Chinese urban community study
Yi-Wei Xia, Yi Shen, Yi Wang, Lumeng Yang +13 more
2020Aging43 citations Open access
Semantic Scholar
Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke
A. Bivard, C. Levi, Long-Ting Lin, Xin Cheng +10 more
2017Stroke43 citations Open access
Semantic Scholar
Permeability Measures Predict Hemorrhagic Transformation after Ischemic Stroke
A. Bivard, T. Kleinig, L. Churilov, C. Levi +9 more
2020Annals of Neurology40 citations Open access
Semantic Scholar
Personalized risk prediction of symptomatic intracerebral hemorrhage after stroke thrombolysis using a machine-learning model
Feng Wang, Yuanhanqing Huang, Yong Xia, Wei Zhang +12 more
2020Therapeutic Advances in Neurological Disorders38 citations Open access
Semantic Scholar
ADAMTS13: An Emerging Target in Stroke Therapy
Xin Chen, Xin Cheng, Shufan Zhang, Dan-Hong Wu
2019Frontiers in Neurology38 citations Open access
Semantic Scholar
Cerebral Amyloid Angiopathy (CAA)-Related Inflammation: Comparison of Inflammatory CAA and Amyloid-β-Related Angiitis
Shuguang Chu, Feijia Xu, Ya Su, Hong Chen +1 more
2016Journal of Alzheimer's Disease38 citations
Semantic Scholar
Too good to treat? ischemic stroke patients with small computed tomography perfusion lesions may not benefit from thrombolysis
A. Bivard, M. Lou, C. Levi, Venkatesh Krishnamurthy +11 more
2016Annals of Neurology32 citations Open access
Semantic Scholar
Occludin deficiency with BACE1 elevation in cerebral amyloid angiopathy
Xin Cheng, P. He, Hai-Lan Yao, Q. Dong +2 more
2014Neurology31 citations Open access
Semantic Scholar
Risk Factors and Stroke Characteristic in Patients with Postoperative Strokes.
Yi Dong, W. Cao, Xin Cheng, K. Fang +4 more
2017Journal of Stroke & Cerebrovascular Diseases29 citations
Semantic Scholar
Neurofilament light chain predicts risk of recurrence in cerebral amyloid angiopathy-related intracerebral hemorrhage
Xin Cheng, Ya Su, Qiong Wang, Feng Gao +7 more
2020Aging28 citations Open access
Semantic Scholar
Permeability Surface of Deep Middle Cerebral Artery Territory on Computed Tomographic Perfusion Predicts Hemorrhagic Transformation After Stroke
Qiao Li, Xinyi Gao, Zhenwei Yao, Xiao-Yuan Feng +7 more
2017Stroke28 citations
Semantic Scholar
Tau PET Imaging with [18F]PM-PBB3 in Frontotemporal Dementia with MAPT Mutation
Ya Su, Jiayu Fu, Jin-Tai Yu, Qian-Hua Zhao +5 more
2020Journal of Alzheimer's Disease26 citations
Semantic Scholar
Higher fasting glucose next day after intravenous thrombolysis is independently associated with poor outcome in acute ischemic stroke.
W. Cao, Yi-Feng Ling, Fei Wu, Lumeng Yang +2 more
2015Journal of Stroke & Cerebrovascular Diseases25 citations
Semantic Scholar
Relationship between changes in resting-state spontaneous brain activity and cognitive impairment in patients with CADASIL
Jing-Jing Su, Mengxing Wang, Shiyu Ban, Liang Wang +7 more
2019The Journal of Headache and Pain22 citations Open access
Semantic Scholar
Tenecteplase thrombolysis for stroke up to 24 hours after onset with perfusion imaging selection: the umbrella phase IIa CHABLIS-T randomised clinical trial
Xin Cheng, L. Hong, L. Churilov, Long-Ting Lin +21 more
2024Stroke and vascular neurology20 citations Open access
Semantic Scholar
Neuroimaging Prediction of Hemorrhagic Transformation for Acute Ischemic Stroke
L. Hong, T. Hsu, Yiran Zhang, Xin Cheng
2022Cerebrovascular Diseases20 citations
Semantic Scholar
Influence of Penumbral Reperfusion on Clinical Outcome Depends on Baseline Ischemic Core Volume
Chu-Shuang Chen, M. Parsons, M. Clapham, C. Oldmeadow +8 more
2017Stroke20 citations
Semantic Scholar
Global White Matter Hypoperfusion on CT Predicts Larger Infarcts and Hemorrhagic Transformation after Acute Ischemia
A. Bivard, Xin Cheng, Long-Ting Lin, C. Levi +11 more
2016CNS Neuroscience & Therapeutics20 citations Open access
Semantic Scholar
Glymphatic Pathway in Sporadic Cerebral Small Vessel Diseases: From Bench to Bedside.
Jia-Jie Xu, Ya Su, Jiayu Fu, Yong Shen +2 more
2023Ageing Research Reviews19 citations
Semantic Scholar
White matter hyperintensities induce distal deficits in the connected fibers
Yan-Peng Liu, Yi-Wei Xia, Xiao-Xiao Wang, Yan-Ming Wang +16 more
2021Human Brain Mapping19 citations Open access
Semantic Scholar
Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis
Chu-Shuang Chen, M. Parsons, C. Levi, N. Spratt +8 more
2019Neurology18 citations
Semantic Scholar
Quantifying reperfusion of the ischemic region on whole-brain computed tomography perfusion
Long-Ting Lin, Xin Cheng, A. Bivard, C. Levi +2 more
2017Journal of Cerebral Blood Flow and Metabolism17 citations Open access
Semantic Scholar
Clinical features and long exercise test in Chinese patients with Andersen‐Tawil syndrome
Jie Song, Su-Shan Luo, Xin Cheng, D. Yue +6 more
2016Muscle and Nerve17 citations
Semantic Scholar
Optimal CT perfusion thresholds for core and penumbra in acute posterior circulation infarction
L. Edwards, C. Cappelen-Smith, D. Cordato, A. Bivard +11 more
2023Frontiers in Neurology15 citations Open access
Semantic Scholar
Reduced resting-state brain functional network connectivity and poor regional homogeneity in patients with CADASIL
Jing-Jing Su, Shiyu Ban, Mengxing Wang, Feng-Chun Hua +7 more
2019The Journal of Headache and Pain15 citations Open access
Semantic Scholar
Dual Antiplatelet Therapy of Clopidogrel and Aspirin in Secondary Prevention of Ischemic Stroke: Evidence and Indications
Ya Su, Xin Cheng, Q. Dong
2015CNS Neuroscience & Therapeutics15 citations Open access
Semantic Scholar
Incident cerebral microbleeds and hypertension defined by the 2017 ACC/AHA Guidelines
Yi-Wei Xia, Yi Wang, Lumeng Yang, Yi-Qing Wang +9 more
2021Annals of Translational Medicine14 citations Open access
Semantic Scholar
Low-dose intravenous tissue plasminogen activator for acute ischaemic stroke: an alternative or a new standard?
Yi Dong, W. Cao, Xin Cheng, K. Fang +4 more
2016Stroke and vascular neurology14 citations Open access
Semantic Scholar
Value of Perfusion Computed Tomography in Acute Ischemic Stroke: Diagnosis of Infarct Core and Penumbra
Jiawei Pan, Jun Zhang, Weiyuan Huang, Xin Cheng +3 more
2013Journal of computer assisted tomography14 citations
Semantic Scholar
Effect of intravenous urokinase vs best medicine treatment on functional outcome for patients with acute minor stroke (TRUST): a randomized controlled trial
Yong-Li Tao, Yuan Gao, Lu Zhao, Yafang Xu +22 more
2025BMC Medicine13 citations
Semantic Scholar
Predictors of clinical outcome in patients with acute perforating artery infarction.
Lumeng Yang, W. Cao, Fei Wu, Yi-Feng Ling +2 more
2016Journal of Neurological Sciences13 citations
Semantic Scholar
Association of Endovascular Thrombectomy With Functional Outcome in Patients With Acute Stroke With a Large Ischemic Core
C. Garcia-Esperon, A. Bivard, H. Johns, Chu-Shuang Chen +12 more
2022Neurology12 citations
Semantic Scholar
The Use of Serum Matrix Metalloproteinases in Cerebral Amyloid Angiopathy-Related Intracerebral Hemorrhage and Cognitive Impairment
Mingxu Xia, Ya Su, Jiayu Fu, Jia-Jie Xu +5 more
2021Journal of Alzheimer's Disease12 citations
Semantic Scholar
The benefit of favorable venous outflow profile is mediated through reduced microvascular dysfunction in acute ischemic stroke
Si-Yuan Li, L. Hong, Wen-Hao Yang, Xinyu Liu +8 more
2024European Stroke Journal11 citations Open access
Semantic Scholar
Lenticulostriate arteries appearance before thrombectomy predicts good outcome in acute middle cerebral artery occlusion
Fei-Feng Liu, Chen Chen, L. Hong, Hao Shen +8 more
2019BMC Neurology11 citations Open access
Semantic Scholar
Causal Relations between Exposome and Stroke: A Mendelian Randomization Study
Hong-Qi Li, Yi-Wei Feng, Yu‐Xiang Yang, Xin'yi Leng +12 more
2022Journal of Stroke10 citations Open access
Semantic Scholar
Association of Admission NIHSS Score with Infarct Core Volume and Target Mismatch of Infarct Core/Penumbra Volume on CT Perfusion in Acute Ischaemic Stroke
W. Cao, Yi-Feng Ling, Lumeng Yang, Fei Wu +3 more
2021Cerebrovascular Diseases10 citations
Semantic Scholar
Real-World Cost-Effectiveness of Late Time Window Thrombectomy for Patients With Ischemic Stroke
Lan Gao, A. Bivard, M. Parsons, N. Spratt +14 more
2021Frontiers in Neurology10 citations Open access
Semantic Scholar
Validation of external and internal exposome of the findings associated to cerebral small vessel disease: A Mendelian randomization study
Xue-Qing Zhang, Yu‐Xiang Yang, Can Zhang, Xin'yi Leng +11 more
2022Journal of Cerebral Blood Flow and Metabolism8 citations Open access
Semantic Scholar
Hemispheric cerebral blood flow predicts outcome in acute small subcortical infarcts
L. Hong, Yi-Feng Ling, Ya Su, Lumeng Yang +4 more
2021Journal of Cerebral Blood Flow and Metabolism8 citations Open access
Semantic Scholar

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