J. Groves

Most-cited papers

Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins
Xiong-Yi Huang, J. Groves
2017Chemical Reviews788 citations Open access
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Oxidative Aliphatic C-H Fluorination with Fluoride Ion Catalyzed by a Manganese Porphyrin
Wei Liu, Xiong-Yi Huang, Mu-jeng Cheng, Robert J. Nielsen +2 more
2012Science447 citations
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Manganese Catalyzed C-H Halogenation.
Wei Liu, J. Groves
2015Accounts of Chemical Research349 citations
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Efficient water oxidation catalyzed by homogeneous cationic cobalt porphyrins with critical roles for the buffer base
Dong Wang, J. Groves
2013Proceedings of the National Academy of Sciences of the United States of America319 citations Open access
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Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C–H activation
Xiong-Yi Huang, J. Groves
2016JBIC Journal of Biological Inorganic Chemistry268 citations Open access
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Manganese porphyrins catalyze selective C-H bond halogenations.
Wei Liu, J. Groves
2010Journal of the American Chemical Society253 citations
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Manganese-catalyzed late-stage aliphatic C-H azidation.
Xiong-Yi Huang, Tova M Bergsten, J. Groves
2015Journal of the American Chemical Society250 citations
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Late stage benzylic C-H fluorination with [¹⁸F]fluoride for PET imaging.
Xiong-Yi Huang, Wei Liu, Hong Ren, Ramesh Neelamegam +2 more
2014Journal of the American Chemical Society194 citations
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Manganese-catalyzed oxidative benzylic C-H fluorination by fluoride ions.
Wei Liu, J. Groves
2013Angewandte Chemie194 citations
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Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form
M. Nelp, Patrick A. Kates, J. T. Hunt, J. Newitt +11 more
2018Proceedings of the National Academy of Sciences of the United States of America176 citations Open access
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A Highly Reactive P450 Model Compound I
Seth R Bell, J. Groves
2009Journal of the American Chemical Society153 citations Open access
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Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats.
I. Obrosova, V. Drel, Christine L. Oltman, N. Mashtalir +3 more
2007American Journal of Physiology. Endocrinology and Metabolism145 citations
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ENZYMATIC C–H BOND ACTIVATION
J. Groves
2014Nature Chemistry137 citations Open access
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Targeted fluorination with the fluoride ion by manganese-catalyzed decarboxylation.
Xiong-Yi Huang, Wei Liu, J. Hooker, J. Groves
2015Angewandte Chemie131 citations
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Cytochrome c causes pore formation in cardiolipin-containing membranes
Christina L. Bergstrom, P. Beales, Yang Lv, T. Vanderlick +1 more
2013Proceedings of the National Academy of Sciences of the United States of America131 citations Open access
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Taming Azide Radicals for Catalytic C–H Azidation
Xiong-Yi Huang, J. Groves
2016128 citations
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A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.
V. Drel, P. Pacher, I. Vareniuk, I. Pavlov +5 more
2007European Journal of Pharmacology126 citations Open access
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Trans-dioxo manganese(V) porphyrins.
Ning-Ren Jin, Mohammed Salah Ibrahim, T. Spiro, J. Groves
2007Journal of the American Chemical Society124 citations Open access
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Detection and Kinetic Characterization of a Highly Reactive Heme–Thiolate Peroxygenase Compound I
Xiaoshi Wang, S. Peter, M. Kinne, M. Hofrichter +1 more
2012Journal of the American Chemical Society122 citations Open access
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Radical intermediates in monooxygenase reactions of rieske dioxygenases.
Sarmistha Chakrabarty, R. Austin, Da-Yi Deng, J. Groves +1 more
2007Journal of the American Chemical Society100 citations Open access
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A "push-pull" mechanism for heterolytic o-o bond cleavage in hydroperoxo manganese porphyrins.
Ning-Ren Jin, Dorothée Lahaye, J. Groves
2010Inorganic Chemistry90 citations
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Mechanisms of Peroxynitrite Interactions with Heme Proteins
Jia-Yang Su, J. Groves
2010Inorganic Chemistry83 citations Open access
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Heme-thiolate ferryl of aromatic peroxygenase is basic and reactive
Xiaoshi Wang, R. Ullrich, M. Hofrichter, J. Groves
2015Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
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Peroxynitrite and Protein Nitration in the Pathogenesis of Diabetic Peripheral Neuropathy
R. Stavniichuk, Hanna Shevalye, S. Lupachyk, A. Obrosov +3 more
2014Diabetes/Metabolism Research Reviews75 citations Open access
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Alkane-oxidizing metalloenzymes in the carbon cycle.
R. Austin, J. Groves
2011Metallomics72 citations
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Selective C-H Halogenation with a Highly Fluorinated Manganese Porphyrin.
Gang Li, Andrew K. Dilger, Peter T. W. Cheng, W. Ewing +1 more
2018Angewandte Chemie69 citations
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Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice.
I. Vareniuk, I. Pavlov, V. Drel, V. Lyzogubov +5 more
2007Experimental Neurology68 citations
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Alkyl Isocyanates via Manganese-Catalyzed C-H Activation for the Preparation of Substituted Ureas.
Xiong-Yi Huang, Thompson Zhuang, Patrick A. Kates, Hongxin Gao +2 more
2017Journal of the American Chemical Society67 citations
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The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry
Chun H. Hsieh, Xiong-Yi Huang, J. Amaya, Cooper Rutland +4 more
2017Biochemistry67 citations Open access
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Dynamics of Carbon Monoxide Binding to Cystathionine β-Synthase*
Mrinalini Puranik, Colin L. Weeks, Dorothée Lahaye, O. Kabil +5 more
2006Journal of Biological Chemistry67 citations Open access
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Ferryl Protonation in Oxoiron(IV) Porphyrins and Its Role in Oxygen Transfer
Nicholas C. Boaz, Seth R Bell, J. Groves
2015Journal of the American Chemical Society65 citations Open access
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Direct Detection of the Oxygen Rebound Intermediates, Ferryl Mb and NO2, in the Reaction of metMyoglobin with Peroxynitrite
Jia-Yang Su, J. Groves
2009Journal of the American Chemical Society64 citations Open access
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A conformational switch to beta-sheet structure in cytochrome c leads to heme exposure. Implications for cardiolipin peroxidation and apoptosis.
G. Balakrishnan, Ying Hu, Oyeyemi F. Oyerinde, Jia-Yang Su +2 more
2007Journal of the American Chemical Society63 citations Open access
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Evaluation of the peroxynitrite decomposition catalyst Fe(III) tetra-mesitylporphyrin octasulfonate on peripheral neuropathy in a mouse model of type 1 diabetes.
V. Drel, P. Pacher, I. Vareniuk, I. Pavlov +5 more
2007International Journal of Molecular Medicine62 citations Open access
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Driving Force for Oxygen Atom Transfer by Heme-Thiolate Enzymes
Xiaoshi Wang, S. Peter, R. Ullrich, Martibn Hofrichter +1 more
2013Angewandte Chemie58 citations Open access
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The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction.
T. Radovits, L. Seres, D. Gerő, Li-ni Lin +7 more
2007Mechanisms of Ageing and Development58 citations
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Catalytic generation of chlorine dioxide from chlorite using a water-soluble manganese porphyrin.
Thomas Umile, J. Groves
2011Angewandte Chemie56 citations
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Parallel and Competitive Pathways for Substrate Desaturation, Hydroxylation and Radical Rearrangement by the Non-heme Diiron Hydroxylase AlkB
Harriet L R Cooper, G. Mishra, Xiong-Yi Huang, Marilla Pender-Cudlip +3 more
2012Journal of the American Chemical Society54 citations Open access
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Probing the C–O Bond-Formation Step in Metalloporphyrin-Catalyzed C–H Oxygenation Reactions
Wei Liu, Mu-jeng Cheng, Robert J. Nielsen, W. Goddard +1 more
201752 citations Open access
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Fast Hydrogen Atom Abstraction by a Hydroxo Iron(III) Porphyrazine
Hongxin Gao, J. Groves
2017Journal of the American Chemical Society51 citations Open access
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Molecular Probes of the Mechanism of Cytochrome P450. Oxygen Traps a Substrate Radical Intermediate
Harriet L R Cooper, J. Groves
2010Archives of Biochemistry and Biophysics47 citations Open access
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Oxidative aliphatic C-H fluorination with manganese catalysts and fluoride ion
Wei Liu, Xiong-Yi Huang, J. Groves
2013Nature Protocols45 citations Open access
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Modeling the haloperoxidases: reversible oxygen atom transfer between bromide ion and an oxo-Mn(V) porphyrin.
Dorothée Lahaye, J. Groves
2007Journal of Inorganic Biochemistry41 citations
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Dissection of the mechanism of manganese porphyrin-catalyzed chlorine dioxide generation.
Thomas Umile, Dong Wang, J. Groves
2011Inorganic Chemistry39 citations
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Financial Impact of Palliative Care Consultation in a Public Hospital
E. Bendaly, J. Groves, B. Juliar, G. Gramelspacher
2008Journal of Palliative Medicine39 citations
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Chemistry in the Center for Catalytic Hydrocarbon Functionalization: An Energy Frontier Research Center
Suzanne R Golisz, T. Gunnoe, William A. Iii Goddard, J. Groves +1 more
201138 citations
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Cage escape competes with geminate recombination during alkane hydroxylation by the diiron oxygenase AlkB.
R. Austin, Kate Luddy, K. Erickson, Marilla Pender-Cudlip +5 more
2008Angewandte Chemie38 citations Open access
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Flavin-catalyzed insertion of oxygen into rhenium-methyl bonds.
Mark J. Pouy, E. Milczek, Travis M. Figg, Brooke M. Otten +4 more
2012Journal of the American Chemical Society36 citations Open access
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Profiling mechanisms of alkane hydroxylase activity in vivo using the diagnostic substrate norcarane.
Elena A Rozhkova-Novosad, J. Chae, G. Zylstra, Erin M. Bertrand +7 more
2007Chemistry and Biology36 citations Open access
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Potent Activation of Indoleamine 2,3-Dioxygenase by Polysulfides.
M. Nelp, Vincent Zheng, K. Davis, K. Stiefel +1 more
2019Journal of the American Chemical Society31 citations
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