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L. Hitzel · SciRah

Researcher profile · Semantic Scholar

L. Hitzel

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L. Hitzel — researcher profile on SciRah

h-index: 11
Works: 17
Citations: 443

Most-cited papers

3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT(2A) receptor antagonists.
M. Rowley, D. Hallett, S. Goodacre, C. Moyes +11 more
2001Journal of Medicinal Chemistry94 citations Open access
Semantic Scholar
Effect of increasing concentration of ammonium acetate as an additive in supercritical fluid chromatography using CO2-methanol mobile phase.
A. Cazenave-Gassiot, R. Boughtflower, J. Caldwell, L. Hitzel +6 more
2009Journal of Chromatography A76 citations
Semantic Scholar
4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors
I. Churcher, D. Beher, J. Best, J. L. Castro +16 more
200670 citations Open access
Semantic Scholar
An Increased Throughput Method for the Determination of Partition Coefficients
L. Hitzel, A. Watt, Karen L. Locker
2000Pharmaceutical Research61 citations
Semantic Scholar
Selectivity optimization in green chromatography by gradient stationary phase optimized selectivity liquid chromatography.
Kai Chen, F. Lynen, Maarten de Beer, L. Hitzel +3 more
2010Journal of Chromatography A46 citations
Semantic Scholar
Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring.
K. Gibson, L. Hitzel, R. Mortishire-Smith, U. Gerhard +5 more
2002Journal of Organic Chemistry30 citations
Semantic Scholar
Lead Diversification 2: application to P38, gMTP and lead compounds.
M. Masood, M. Bazin, Mark E. Bunnage, Andrew Calabrese +7 more
2012Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Prediction of retention for sulfonamides in supercritical fluid chromatography.
A. Cazenave-Gassiot, R. Boughtflower, J. Caldwell, Richard Coxhead +6 more
2008Journal of Chromatography A12 citations
Semantic Scholar
Ionisation in the absence of high voltage using supercritical fluid chromatography: a possible route to increased signal.
Mohini A. Thite, R. Boughtflower, J. Caldwell, L. Hitzel +6 more
2008Rapid Communications in Mass Spectrometry12 citations
Semantic Scholar
4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors.
I. Churcher, D. Beher, J. Best, J. L. Castro +16 more
2006Bioorganic & Medicinal Chemistry Letters11 citations
Semantic Scholar
Parallel synthesis of 3-aryloxy-2-propanolamines and evaluation as dual affinity 5-HT(1A) and 5-HT re-uptake ligands.
M. B. Van Niel, M. Beer, J. L. Castro, Susan K. F. Cheng +8 more
1999Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
A New Strategy for Fast Chiral Screening by Combining HPLC-DAD with a Multivariate Curve Resolution–Alternating Least Squares Algorithm
Kai Chen, F. Lynen, L. Hitzel, Melissa Hanna-Brown +2 more
2013Chromatographia4 citations
Semantic Scholar
Enantiomeric separation of substituted 2-arylindoles on derivatised polysaccharide chiral stationary phases.
A. Watt, L. Hitzel, R. Mortishire-Smith
2002Journal of Biochemical and Biophysical Methods2 citations
Semantic Scholar
A concise synthesis of chiral indanes as α1A adrenoceptor partial agonists
Lee R. Roberts, M. Corbett, Steven J. Fussell, L. Hitzel +7 more
20151 citations
Semantic Scholar
CHIRAL SEPARATION OF 4,4-DISUBSTITUTED PIPERIDINYL SUBSTANCE P ANTAGONISTS
A. Watt, L. Hitzel
20001 citations
Semantic Scholar
A new strategy for fast chiral screening by HPLC hyphenated with multivariate curve resolution-alternating least squares algorithm
Kai Chen, F. Lynen, L. Hitzel, P. Sandra
20120 citations
Semantic Scholar
Extending phase optimized liquid chromatography (POPLC) to green chromatography
Kai Chen, Maarten de Beer, L. Hitzel, F. Lynen +1 more
20090 citations
Semantic Scholar

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