Cuifen Hou

Most-cited papers

1. In Vivo Activity of a Phospholipase C Inhibitor, 1-(6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in Acute and Chronic Inflammatory Reactions

   Cuifen Hou, T. Kirchner, M. Singer, Michele Matheis +2 more

   2004Journal of Pharmacology and Experimental Therapeutics72 citations

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2. Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

   B. Lagu, Chrissy Gerchak, Meng Pan, Cuifen Hou +6 more

   2007Bioorganic & Medicinal Chemistry Letters27 citations Open access

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3. A novel series of N-(azetidin-3-yl)-2-(heteroarylamino)acetamide CCR2 antagonists.

   N. Subasinghe, J. Lanter, Thomas P. Markotan, E. Opas +6 more

   2013Bioorganic & Medicinal Chemistry Letters21 citations Open access

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4. Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

   Mingde Xia, Cuifen Hou, D. Demong, Scott R Pollack +10 more

   2007Journal of Medicinal Chemistry21 citations Open access

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5. Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.

   Jay M. Matthews, J. Mcnally, P. Connolly, Mingde Xia +7 more

   2016Bioorganic & Medicinal Chemistry Letters20 citations Open access

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6. Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.

   Xu-Qing Zhang, H. Hufnagel, Thomas P. Markotan, J. Lanter +8 more

   2011Bioorganic & Medicinal Chemistry Letters20 citations Open access

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7. Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists.

   Xu-Qing Zhang, Z. Sui, J. Kauffman, Cuifen Hou +7 more

   2017Bioorganic & Medicinal Chemistry Letters19 citations Open access

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8. Synthesis and structure-activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists.

   Mingde Xia, Cuifen Hou, D. Demong, Scott R. Pollack +6 more

   2008Bioorganic & Medicinal Chemistry Letters13 citations Open access

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9. 6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB1) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity.

   Yue-Mei Zhang, M. Greco, M. Macielag, C. Teleha +12 more

   2018Journal of Medicinal Chemistry12 citations Open access

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10. Discovery of a 4-Azetidinyl-1-thiazoyl-cyclohexane CCR2 Antagonist as a Development Candidate.

    Xu-Qing Zhang, Cuifen Hou, H. Hufnagel, M. Singer +4 more

    2012ACS Medicinal Chemistry Letters12 citations Open access

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11. Substituted dipiperidine alcohols as potent CCR2 antagonists.

    Mingde Xia, Cuifen Hou, D. Demong, Scott R. Pollack +6 more

    2008Bioorganic & Medicinal Chemistry Letters12 citations Open access

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12. Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes.

    Xu-Qing Zhang, M. Wall, Z. Sui, J. Kauffman +8 more

    2017ACS Medicinal Chemistry Letters11 citations Open access

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13. Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists.

    C. Cai, Fu-An Kang, Cuifen Hou, John C. O'Neill +4 more

    2013Bioorganic & Medicinal Chemistry Letters10 citations Open access

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14. Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.

    Xu-Qing Zhang, H. Hufnagel, Cuifen Hou, E. Opas +5 more

    2011Bioorganic & Medicinal Chemistry Letters10 citations Open access

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15. The discovery of novel cyclohexylamide CCR2 antagonists.

    J. Lanter, Thomas P. Markotan, Xu-Qing Zhang, N. Subasinghe +9 more

    2011Bioorganic & Medicinal Chemistry Letters9 citations Open access

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16. Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.

    Mingde Xia, Cuifen Hou, Scott R. Pollack, James Brackley +7 more

    2007Bioorganic & Medicinal Chemistry Letters9 citations Open access

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17. Discovery and SAR of 5-aminooctahydrocyclopentapyrrole-3a-carboxamides as potent CCR2 antagonists.

    C. Cai, D. McComsey, Cuifen Hou, John C. O'Neill +4 more

    2014Bioorganic & Medicinal Chemistry Letters6 citations Open access

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18. The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2.

    Michael P. Winters, C. Teleha, Fu-An Kang, D. McComsey +6 more

    2014Bioorganic & Medicinal Chemistry Letters6 citations Open access

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19. Tetrahydropyrazolo[4,3-c]pyridine derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.

    Bin Zhu, Jay M. Matthews, Mingde Xia, S. Black +5 more

    2016Bioorganic & Medicinal Chemistry Letters5 citations Open access

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20. CHAPTER 12:CCR2 Antagonists for the Treatment of Diseases Associated with Inflammation

    Cuifen Hou, Z. Sui

    20124 citations

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21. Discovery of Orally E ffi cacious Tetrahydrobenzimidazoles as TGR 5 Agonists for Type 2 Diabetes

    Xu-Qing Zhang, M. Wall, Z. Sui, Cuifen Hou +7 more

    20170 citations

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22. Antagonists of 4-azetidinyl-1-phenyl-cyclohexane CCR2

    Xu-Qing Zhang, Heather Rae Hufnagal, Cuifen Hou, Dana L. Johnson +1 more

    20100 citations

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23. Antagonists 4-azetidinyl-1-cyclohexanol heteroaryl CCR2

    Xu-Qing Zhang, H. Hufnagel, Cuifen Hou, Dana L. Johnson +3 more

    20090 citations

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