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D. le-Nguyen · SciRah

Researcher profile · Semantic Scholar

D. le-Nguyen

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D. le-Nguyen — researcher profile on SciRah

h-index: 23
Works: 57
Citations: 2,057

Most-cited papers

PyBOP®: A new peptide coupling reagent devoid of toxic by-product
J. Coste, D. le-Nguyen, B. Castro
1990517 citations
Semantic Scholar
Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins.
A. Heitz, Jean-François Hernandez, J. Gagnon, Thai Trinh Hong +4 more
2001Biochemistry168 citations
Semantic Scholar
Squash inhibitors: from structural motifs to macrocyclic knottins.
L. Chiche, A. Heitz, Jean-Christophe Gelly, J. Gracy +4 more
2004Current protein and peptide science167 citations
Semantic Scholar
KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007
J. Gracy, D. le-Nguyen, Jean-Christophe Gelly, Q. Kaas +2 more
2007Nucleic Acids Res.127 citations Open access
Semantic Scholar
The KNOTTIN website and database: a new information system dedicated to the knottin scaffold
Jean-Christophe Gelly, J. Gracy, Q. Kaas, D. le-Nguyen +2 more
2004Nucleic Acids Res.112 citations Open access
Semantic Scholar
1H 2D NMR and distance geometry study of the folding of Ecballium elaterium trypsin inhibitor, a member of the squash inhibitors family.
Annie Heitz, Laurent Chiche, D. le-Nguyen, B. Castro
1989Biochemistry90 citations
Semantic Scholar
Knottin cyclization: impact on structure and dynamics
A. Heitz, O. Avrutina, D. le-Nguyen, U. Diederichsen +4 more
2008BMC Structural Biology74 citations Open access
Semantic Scholar
Comparative enzymatic studies of human renin acting on pure natural or synthetic substrates.
Frédéric Cumin, D. le-Nguyen, B. Castro, J. Mènard +1 more
1987Biochimica et Biophysica Acta65 citations
Semantic Scholar
Characterization and 2D NMR study of the stable [9–21, 15–27] 2 disulfide intermediate in the folding of the 3 disulfide trypsin inhibitor EETI II
D. le-Nguyen, A. Heitz, L. Chiche, M. ElHajji +1 more
1993Protein Science57 citations Open access
Semantic Scholar
Renin substrates. Part 2. Rapid solid phase synthesis of the ratine sequence tetradecapeptide using BOP reagent
D. le-Nguyen, A. Heitz, B. Castro
198752 citations
Semantic Scholar
Min-21 and min-23, the smallest peptides that fold like a cystine-stabilized beta-sheet motif: design, solution structure, and thermal stability.
Annie Heitz, D. le-Nguyen, Laurent Chiche
1999Biochemistry47 citations
Semantic Scholar
Glucagon-(19-29), a Ca2+ pump inhibitory peptide, is processed from glucagon in the rat liver plasma membrane by a thiol endopeptidase.
Philippe Blache, A. Kervran, M. Dufour, Jean Martinez +5 more
1990Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Cell-permeable peptide-based disruption of endogenous PKA-AKAP complexes: a tool for studying the molecular roles of AKAP-mediated PKA subcellular anchoring.
O. Faruque, D. le-Nguyen, A. Lajoix, E. Vivés +3 more
2009American Journal of Physiology - Cell Physiology41 citations
Semantic Scholar
Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B.
G. Fontes, A. Lajoix, F. Bergeron, S. Cadel +7 more
2005Endocrinology40 citations
Semantic Scholar
Miniglucagon (Glucagon 19–29), a Potent and Efficient Inhibitor of Secretagogue-induced Insulin Release through a Ca2+Pathway*
S. Dalle, Paul A. Smith, P. Blache, D. le-Nguyen +4 more
1999Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Computational Reverse-Engineering of a Spider-Venom Derived Peptide Active Against Plasmodium falciparum SUB1
Giacomo Bastianelli, Anthony Bouillon, C. Nguyen, Elodie Crublet +5 more
2011PLoS ONE37 citations Open access
Semantic Scholar
Solid phase synthesis of a trypsin inhibitor isolated from the Cucurbitaceae Ecballium elaterium.
D. le-Nguyen, Dominique Nalis, B. Castro
2009International journal of peptide & protein research36 citations
Semantic Scholar
Miniglucagon [glucagon-(19-29)] is a component of the positive inotropic effect of glucagon.
Catherine Pavoine, V. Brechler, A. Kervran, Philippe Blache +4 more
1991American Journal of Physiology35 citations
Semantic Scholar
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
Sophie Lotersztajn, Catherine Pavoine, V. Brechler, B. Roche +4 more
1990Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Determination of the structure of [Nle7]-endothelin by 1H NMR.
André Aumelas, Laurent Chiche, E. Mahé, D. le-Nguyen +3 more
2009International journal of peptide & protein research32 citations
Semantic Scholar
Oxyntomodulin and glicentin are potent inhibitors of the fed motility pattern in small intestine
S. Pellissier, K. Sasaki, D. le-Nguyen, D. Bataille +1 more
2004Neurogastroenterology and Motility31 citations
Semantic Scholar
Active site chemical mutagenesis of Ecballium elaterium trypsin inhibitor II: new microproteins inhibiting elastase and chymotrypsin.
A. Favel, D. le-Nguyen, M. Coletti-previero, B. Castro
1989Biochemical and Biophysical Research Communications - BBRC25 citations
Semantic Scholar
Solution conformation of a synthetic bis-headed inhibitor of trypsin and carboxypeptidase A: new structural alignment between the squash inhibitors and the potato carboxypeptidase inhibitor.
Laurent Chiche, Annie Heitz, A. Padilla, D. le-Nguyen +1 more
1993Protein Engineering24 citations
Semantic Scholar
Folding of the squash trypsin inhibitor EETI II. Evidence of native and non-native local structural preferences in a linear analogue.
Annie Heitz, Laurent Chiche, D. le-Nguyen, B. Castro
1995European Journal of Biochemistry23 citations Open access
Semantic Scholar
Endopeptidase from rat liver membranes, which generates miniglucagon from glucagon.
Philippe Blache, A. Kervran, D. le-Nguyen, M. Dufour +3 more
1993Journal of Biological Chemistry23 citations
Semantic Scholar
Immunological detection of prohormone convertases in two different proglucagon processing cell lines
P. Blache, D. le-Nguyen, Catherine Boegner-Lemoine, A. Cohen-Solal +2 more
1994FEBS Letters19 citations Open access
Semantic Scholar
(1)H NMR Study of the solution structure of sarafotoxin-S6b.
A. Aumelas, L. Chiche, E. Mahé, D. le-Nguyen +3 more
1991Neurochemistry International17 citations
Semantic Scholar
Design and chemical synthesis of a 32 residues chimeric microprotein inhibiting both trypsin and carboxypeptidase A.
D. le-Nguyen, H. Mattras, M. Coletti-previero, B. Castro
1989Biochemical and Biophysical Research Communications - BBRC17 citations
Semantic Scholar
Role of Asn(2) and Glu(7) residues in the oxidative folding and on the conformation of the N-terminal loop of apamin.
D. le-Nguyen, L. Chiche, F. Hoh, M. Martin-Eauclaire +4 more
2007Biopolymers10 citations Open access
Semantic Scholar
Miniglucagon production from glucagon: an extracellular processing of a hormone used as a prohormone.
Philippe Blache, A. Kervran, D. le-Nguyen, D. Bataille
1994Biochimie8 citations
Semantic Scholar
Crystallization and preliminary X-ray study of porcine trypsin, free and complexed with Ecballium elaterium trypsin inhibitor, a member of the squash inhibitors family.
C. Gaboriaud, M. Vaney, B. Bachet, D. le-Nguyen +2 more
1989Journal of Molecular Biology7 citations
Semantic Scholar
Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease
Giacomo Bastianelli, Anthony Bouillon, C. Nguyen, D. le-Nguyen +2 more
2014PLoS ONE6 citations Open access
Semantic Scholar
Solution structure of the squash trypsin inhibitor EETI-II
L. Chiche, A. Heitz, D. le-Nguyen
20074 citations
Semantic Scholar
Solid-phase synthesis, conformational analysis, and biological activity of AVR9 elicitor peptides of the fungal tomato pathogen Cladosporium fulvum.
E. Mahé, P. Vossen, H. W. van den Hooven, D. le-Nguyen +2 more
1998Journal of Peptide Research4 citations
Semantic Scholar
PyBOP(R) (I): A New Peptide Coupling Reagent Devoid of Toxic By-Product.
J. Coste, D. le-Nguyen, B. Castro
19904 citations
Semantic Scholar
Solid‐phase synthesis, conformational analysis, and biological activity of AVRp elicitor peptides of the fungal tomato pathogen Cladosporium falvum
E. Mahé, P. Vossen, H. W. van den Hooven, D. le-Nguyen +2 more
20093 citations
Semantic Scholar
Miniglucagon: A Local Regulator of Islet Physiology
S. Dalle, P. Blache, D. le-Nguyen, L. Brigand +1 more
1998Annals of the New York Academy of Sciences3 citations
Semantic Scholar
Conformational study of a native monodisulfide bridge analogue of EETI II
A. Heitz, D. le-Nguyen, B. Castro, L. Chiche
2004Letters in peptide science2 citations
Semantic Scholar
SOLUTION STRUCTURE OF THE SQUASH TRYPSIN INHIBITOR MCoTI-II, NMR, 30 STRUCTURES.
A. Heitz, Jean-François Hernandez, J. Gagnon, Thai Trinh Hong +4 more
20012 citations
Semantic Scholar
Conformational study of a native monodisulfide bridge analogue of EETI II
A. Heitz, D. le-Nguyen, B. Castro, L. Chiche
1997Letters in peptide science2 citations
Semantic Scholar
Synthesis and biological activities of some endothelin analogs
E. Mahé, S. Jouquey, M. Fortin, M. Harnois +3 more
19932 citations
Semantic Scholar
TPyClU: A new peptide coupling reagent
F. Roux, J. Coste, E. Frérot, D. le-Nguyen +2 more
19922 citations
Semantic Scholar
Use of HBTU in coupling of amino acids with minimal side-chain protection
D. le-Nguyen, K. Seyer
19911 citations
Semantic Scholar
Renin Substrates. Part 2. Rapid Solid Phase Synthesis of the Ratine Sequence Tetradecapeptide Using BOP Reagent.
D. le-Nguyen, A. Heitz, B. Castro
19871 citations
Semantic Scholar
Solution structure of EETI-II, a Squash Inhibitor Knottin from Ecballium elaterium.
A. Heitz, L. Chiche, D. le-Nguyen, B. Castro
20070 citations
Semantic Scholar
Solution Structure of the Macrocyclic Squash Trypsin Inhibitor MCoTI-II, the First Member of a New Family of Cyclic Knottins
A. Heitz, Jean-François Hernandez, J. Gagnon, Thai Trinh Hong +4 more
20010 citations
Semantic Scholar
Novel peptide derivatives, their preparation and use as medicaments
G. Hamon, E. Mahé, D. le-Nguyen
19930 citations
Semantic Scholar
Hidtil ukendte peptidderivater deres fremstilling og anvendelse som lægemidler
G. Hamon, E. Mahé, D. le-Nguyen
19930 citations
Semantic Scholar
New peptide derivatives, processes for their preparation and their use as medicines
G. Hamon, E. Mahé, D. le-Nguyen
19930 citations
Semantic Scholar
Folding pathway study of EETI II, a knotted microprotein containing three disulfide bridges: Structural characterization of the stable two-bridge intermediate
D. le-Nguyen, A. Heitz, L. Chiche, M. ElHajji +1 more
19930 citations
Semantic Scholar

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