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Constance Agamasu · SciRah

Researcher profile · Semantic Scholar

Constance Agamasu

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Constance Agamasu — researcher profile on SciRah

h-index: 9
Works: 23
Citations: 371

Most-cited papers

Machine learning–driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins
H. Ingólfsson, Chris Neale, T. Carpenter, R. Shrestha +38 more
2020Proceedings of the National Academy of Sciences of the United States of America84 citations Open access
Semantic Scholar
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation
S. Dharmaiah, Timothy H. Tran, S. Messing, Constance Agamasu +9 more
2019Scientific Reports65 citations Open access
Semantic Scholar
The small molecule BI-2852 induces a nonfunctional dimer of KRAS
Timothy H. Tran, P. Alexander, S. Dharmaiah, Constance Agamasu +6 more
2020Proceedings of the National Academy of Sciences of the United States of America57 citations Open access
Semantic Scholar
KRAS Prenylation Is Required for Bivalent Binding with Calmodulin in a Nucleotide-Independent Manner
Constance Agamasu, R. Ghirlando, Troy Taylor, S. Messing +6 more
2019Biophysical Journal43 citations Open access
Semantic Scholar
RASopathy Mutations Provide Functional Insight into the BRAF Cysteine-rich Domain and Demonstrate the Importance of Autoinhibition in BRAF Regulation
Russell Spencer-Smith, Elizabeth M. Terrell, Christine Insinna, Constance Agamasu +5 more
2021bioRxiv25 citations Open access
Semantic Scholar
The Interplay between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt*
Constance Agamasu, R. Ghanam, Fei Xu, Yong Sun +2 more
2016Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt*
Constance Agamasu, R. Ghanam, J. Saad
2015Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
R. Shrestha, T. Carpenter, Que N. Van, Constance Agamasu +16 more
2024Communications Biology19 citations Open access
Semantic Scholar
Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD.
Timothy S Travers, C. López, Constance Agamasu, J. Hettige +4 more
2020Biophysical Journal15 citations Open access
Semantic Scholar
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
A. Maciag, Yue Yang, Alok K. Sharma, David M. Turner +30 more
2025Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Author Correction: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
R. Shrestha, T. Carpenter, Que N. Van, Constance Agamasu +16 more
2024Communications Biology3 citations Open access
Semantic Scholar
Production and Membrane Binding of N-Terminally Acetylated, C-Terminally Farnesylated and Carboxymethylated KRAS4b.
S. Messing, Constance Agamasu, Matthew R. Drew, Caroline J. DeHart +2 more
2021Methods in molecular biology3 citations
Semantic Scholar
Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein.
Constance Agamasu, Peter H. Frank, Shelley Perkins, T. Waybright +3 more
2020Journal of Visualized Experiments2 citations
Semantic Scholar
Abstract PR06: Germline RASopathy mutations provide insights into the differential regulation of RAF family kinases
Russell Spencer-Smith, Elizabeth M. Terrell, Christine Insinna, Constance Agamasu +5 more
2023Molecular Cancer Research0 citations
Semantic Scholar
Emerging Insights into the Membrane Binding Domain of RAF Engaging with the Plasma Membrane and its Implication on RAF Activation
Constance Agamasu, De Chen, J. Columbus, F. Heinrich +6 more
20200 citations Open access
Semantic Scholar
The Multivalent Dynamics of RAF RBD-CRD on Membranes - Enhanced Affinity Due to Recruitment of Anionic Lipids
Timothy S Travers, C. López, Constance Agamasu, J. Hettige +3 more
20200 citations Open access
Semantic Scholar
Abstract A31: Germline RASopathy mutations provide functional insights into the Raf cysteine-rich domain (CRD)
Russell Spencer-Smith, Elizabeth M. Terrell, Constance Agamasu, Daniel A. Ritt +3 more
20200 citations
Semantic Scholar
Biophysical Insights into the KRAS4b-FMe-Calmodulin Interaction
Constance Agamasu, R. Ghirlando, A. Stephen
2019Biophysical Journal0 citations Open access
Semantic Scholar
Abstract 3373: Identification of KRAS membrane bound states using an integrated computational and experimental approach
A. Stephen, Animesh Agarwal, A. Garcia, G. Gnanakaran +28 more
2019Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
SI. The small molecule BI-2852 induces a non- functional dimer of KRAS
Timothy H. Tran, P. Alexander, S. Dharmaiah, Constance Agamasu +7 more
20190 citations
Semantic Scholar
Structural basis for lipid-and calmodulin-mediated Akt activation in breast cancer cells
Constance Agamasu
20160 citations
Semantic Scholar
Structural Basis for Akt Translocation to the PM in Breast Cancer Cells
Constance Agamasu, R. Ghanam, J. Saad
20150 citations
Semantic Scholar
Machine learning–driven multiscale modeling reveals lipid-Machine learning–driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins dependent dynamics of RAS signaling proteins
Helgi I. Ingólfsson, Chris Neale, T. Carpenter, R. Shrestha +40 more
0 citations
Semantic Scholar

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