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Michael A. Curran · SciRah

Researcher profile · Semantic Scholar

Michael A. Curran

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Michael A. Curran — researcher profile on SciRah

h-index: 42
Works: 118
Citations: 10K

Most-cited papers

PD-L1 Expression in Triple Negative Breast Cancer
E. Mittendorf, A. Philips, F. Meric-Bernstam, Na Qiao +13 more
2014Cancer immunology research1,191 citations Open access
Semantic Scholar
Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16–Related Cancer: A Phase 2 Clinical Trial
E. Massarelli, W. William, F. Johnson, M. Kies +17 more
2019JAMA Oncology470 citations Open access
Semantic Scholar
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
Konrad Gabrusiewicz, Benjamin Rodriguez, Jun Wei, Y. Hashimoto +26 more
2016JCI Insight424 citations Open access
Semantic Scholar
Pan-cancer T Cell Atlas Links a Cellular Stress Response State to Immunotherapy Resistance
Yan-Shuo Chu, En-Yu Dai, Yating Li, Guang-Chun Han +41 more
2023Nature Medicine418 citations Open access
Semantic Scholar
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
P. Jayaprakash, Mi-Dan Ai, Arthur J. Liu, Pratha Budhani +14 more
2018Journal of Clinical Investigation344 citations Open access
Semantic Scholar
Oncogenic LncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression
Qingsong Hu, Youqiong Ye, Li-Chuan Chan, Yajuan Li +33 more
2019Nature Immunology315 citations Open access
Semantic Scholar
Ipilimumab with stereotactic ablative radiation therapy: Phase I results and immunologic correlates from peripheral T-cells
Chad Tang, J. Welsh, P. D. de Groot, E. Massarelli +16 more
2016Clinical Cancer Research292 citations Open access
Semantic Scholar
Development of Immunotherapy Combination Strategies in Cancer
T. Yap, E. Parkes, Weiyi Peng, J. Moyers +2 more
2021Cancer Discovery262 citations Open access
Semantic Scholar
4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity
Todd Bartkowiak, Michael A. Curran
2015Frontiers in Oncology246 citations Open access
Semantic Scholar
STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial.
M. Reilley, P. McCoon, C. Cook, P. Lyne +23 more
2018Journal of Immunotherapy for Cancer226 citations Open access
Semantic Scholar
Immune biology of glioma associated macrophages and microglia: Functional and therapeutic implications.
Jun Wei, Pei-Wen Chen, Pravesh Gupta, M. Ott +6 more
2019Neuro-Oncology187 citations Open access
Semantic Scholar
ATR-mediated CD47 and PD-L1 upregulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer
Rodney Cheng-En Hsieh, Sunil Krishnan, Ren-Chin Wu, Akash R. Boda +30 more
2022Science immunology172 citations Open access
Semantic Scholar
Intratumoral STING activation with T-cell checkpoint modulation generates systemic antitumor immunity
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +2 more
2017Cancer immunology research161 citations Open access
Semantic Scholar
Opening of the blood-brain barrier using low-intensity pulsed ultrasound enhances responses to immunotherapy in preclinical glioma models
Aria Sabbagh, Kévin Beccaria, Xiaoyang Ling, Anantha L. Marisetty +17 more
2021Clinical Cancer Research117 citations Open access
Semantic Scholar
ISA101 and nivolumab for HPV-16+ cancer: updated clinical efficacy and immune correlates of response
L. D. de Sousa, K. Rajapakshe, Jaime Rodriguez-Canales, Renee L Chin +14 more
2022Journal for ImmunoTherapy of Cancer100 citations Open access
Semantic Scholar
Role of the tumor microenvironment in mature B-cell lymphoid malignancies
N. Fowler, Che-Ah Y. Chan, R. Gascoyne, J. Gribben +12 more
2016Haematologica98 citations Open access
Semantic Scholar
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine
Todd Bartkowiak, Shailbala Singh, Guojun Yang, Gloria Galvan +5 more
2015Proceedings of the National Academy of Sciences of the United States of America96 citations Open access
Semantic Scholar
Activation of 4-1BB on liver myeloid cells triggers hepatitis via an interleukin-27 dependent pathway
Todd Bartkowiak, A. Jaiswal, C. Ager, Renee L Chin +7 more
2018Clinical Cancer Research90 citations Open access
Semantic Scholar
LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade.
R. Shen, M. Postow, Matthew Adamow, Arshi Arora +20 more
2021Science Translational Medicine87 citations Open access
Semantic Scholar
PD-1 blockade and CD27 stimulation activate distinct transcriptional programs that synergize for CD8+ T-cell driven anti-tumor immunity
Sarah L. Buchan, Mohannad Fallatah, S. Thirdborough, V. Taraban +7 more
2018Clinical Cancer Research87 citations Open access
Semantic Scholar
Anti-PD-1 induces M1 polarization in the glioma microenvironment and exerts therapeutic efficacy in the absence of CD8 cytotoxic T cells
G. Rao, Khatri Latha, M. Ott, Aria Sabbagh +14 more
2020Clinical Cancer Research85 citations Open access
Semantic Scholar
MIF inhibition as a strategy for overcoming resistance to immune checkpoint blockade therapy in melanoma
R. De Azevedo, E. Shoshan, Shanzhi Whang, G. Markel +5 more
2020Oncoimmunology85 citations Open access
Semantic Scholar
Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain
Manisha Singh, Christina Vianden, M. Cantwell, Zhi-Min Dai +14 more
2017Nature Communications81 citations Open access
Semantic Scholar
TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma
M. Reilley, Brittany Morrow, C. Ager, Arthur J. Liu +2 more
2019Journal of Immunotherapy for Cancer69 citations Open access
Semantic Scholar
High potency STING agonists engage unique myeloid pathways to reverse pancreatic cancer immune privilege
C. Ager, Akash R. Boda, K. Rajapakshe, Spencer T. Lea +10 more
2021Journal for ImmunoTherapy of Cancer67 citations Open access
Semantic Scholar
Inhibition of the CD47-SIRPα axis for cancer therapy: A systematic review and meta-analysis of emerging clinical data
Jiang Son, Rodney Cheng-En Hsieh, Heather Y. Lin, K. Krause +5 more
2022Frontiers in Immunology66 citations Open access
Semantic Scholar
Hypoxia Reduction Sensitizes Refractory Cancers to Immunotherapy.
P. Jayaprakash, P. Vignali, Greg M. Delgoffe, Michael A. Curran
2021Annual Review of Medicine66 citations Open access
Semantic Scholar
Tumor-associated nonmyelinating Schwann cell–expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion
Chengcao Sun, Youqiong Ye, Z. Tan, Yuan Liu +27 more
2023Science Advances60 citations Open access
Semantic Scholar
Hormonal Therapies Upregulate MANF and Overcome Female Susceptibility to Immune Checkpoint Inhibitor-Myocarditis
Yaohua Zhang, Cheng-Cao Sun, Yajuan Li, Juan Qin +27 more
2022Science Translational Medicine60 citations Open access
Semantic Scholar
Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
M. Ott, Karl-Heinz Tomaszowski, Anantha L. Marisetty, Ling-Yuan Kong +19 more
2020JCI Insight58 citations Open access
Semantic Scholar
Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype
A. Jaiswal, Arthur J. Liu, S. Pudakalakatti, Prasanta Dutta +16 more
2020Cancer immunology research57 citations Open access
Semantic Scholar
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
S. Jamieson, P. Tsai, Maria Kondratyev, Pratha Budhani +31 more
2018JCI Insight52 citations Open access
Semantic Scholar
New Hope for Therapeutic Cancer Vaccines in the Era of Immune Checkpoint Modulation.
Michael A. Curran, B. Glisson
2019Annual Review of Medicine51 citations Open access
Semantic Scholar
INTRATUMORAL DELIVERY OF STING AGONIST RESULTS IN CLINICAL RESPONSES IN CANINE GLIOBLASTOMA
C. Boudreau, H. Najem, M. Ott, C. Horbinski +5 more
2021Clinical Cancer Research49 citations Open access
Semantic Scholar
IL-6 mediates suppression of T and NK cells function in EMT-associated TKI-resistant EGFR mutant NSCLC
Sonia A Patel, M. Nilsson, Yan Yang, X. Le +13 more
2023Clinical Cancer Research45 citations Open access
Semantic Scholar
Peripheral and tumor immune correlates in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab.
M. Callahan, C. Horak, Michael A. Curran, T. Hollman +16 more
201344 citations
Semantic Scholar
A Phase I Dose Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies
A. Hegde, P. Jayaprakash, C. Couillault, S. Piha-Paul +21 more
2021Clinical Cancer Research42 citations Open access
Semantic Scholar
Immune checkpoint combinations from mouse to man
Mi-Dan Ai, Michael A. Curran
2015Cancer Immunology and Immunotherapy42 citations Open access
Semantic Scholar
Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma
Li-Ran Zhou, Hongmei Husted, Todd T. Moore, Mason Lu +14 more
2018Science Translational Medicine38 citations Open access
Semantic Scholar
Current Landscape and Future Directions of Biomarkers for Immunotherapy in Hepatocellular Carcinoma
Betul Gok Yavuz, E. Hasanov, Sunyoung S. Lee, Yehia I. Mohamed +4 more
2021Journal of Hepatocellular Carcinoma37 citations Open access
Semantic Scholar
Tumor hypermetabolism confers resistance to immunotherapy.
Arthur J. Liu, Michael A. Curran
2020Seminars in Cancer Biology28 citations
Semantic Scholar
Tumor hypoxia drives immune suppression and immunotherapy resistance
Mi-Dan Ai, Pratha Budhani, Jie Sheng, S. Balasubramanyam +5 more
2015Journal of Immunotherapy for Cancer24 citations Open access
Semantic Scholar
Peripheral and tumor immune correlates in patients with advanced melanoma treated with nivolumab (anti-PD-1, BMS-936558, ONO-4538) monotherapy or in combination with ipilimumab
M. Postow, Diana M. Cardona, J. Taube, R. Anders +11 more
2014Journal of Translational Medicine24 citations Open access
Semantic Scholar
Directed Evolution of PD-L1 Targeted Affibodies by mRNA Display
B. Grindel, B. J. Engel, Justin N. Ong, Anupallavi Srinivasamani +7 more
2022ACS Chemical Biology19 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
Response to "Ipilimumab (Yervoy) and the TGN1412 catastrophe".
Michael A. Curran, M. Callahan, S. Subudhi, J. Allison
2012Immunobiology17 citations
Semantic Scholar
cGAS-STING pathway targeted therapies and their applications in the treatment of high-grade glioma
Shashwat Tripathi, H. Najem, Akanksha Mahajan, Peng Zhang +6 more
2022F1000Research16 citations Open access
Semantic Scholar
Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system
Jun Wei, R. Song, Aria Sabbagh, Anantha L. Marisetty +11 more
2022Oncoimmunology14 citations Open access
Semantic Scholar
mRNA display discovery of a novel PD-L1 binding peptide (a peptide ligand for PD-L1)
Golnaz Kamalinia, B. J. Engel, Anupallavi Srinivasamani, B. Grindel +5 more
2020ACS Chemical Biology14 citations Open access
Semantic Scholar
Phase 1 trial of TLR9 agonist lefitolimod in combination with CTLA-4 checkpoint inhibitor ipilimumab in advanced tumors.
M. Reilley, A. Tsimberidou, S. Piha-Paul, T. Yap +12 more
2019Journal of Clinical Oncology12 citations
Semantic Scholar

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