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Maria-José U. Ferreira · SciRah

Researcher profile · Semantic Scholar

Maria-José U. Ferreira

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Maria-José U. Ferreira — researcher profile on SciRah

h-index: 37
Works: 151
Citations: 3,917

Most-cited papers

Molecular Docking Characterizes Substrate-Binding Sites and Efflux Modulation Mechanisms within P-Glycoprotein
Ricardo J. Ferreira, Maria-José U. Ferreira, D. D. dos Santos
2013Journal of Chemical Information and Modeling151 citations
Semantic Scholar
Insights on P-Glycoprotein's Efflux Mechanism Obtained by Molecular Dynamics Simulations.
Ricardo J. Ferreira, Maria-José U. Ferreira, D. D. dos Santos
2012Journal of Chemical Theory and Computation125 citations
Semantic Scholar
Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique.
Xuan Luo, David Pires, J. Aínsa, Begoña Gracia +4 more
2011Journal of Ethnopharmacology103 citations Open access
Semantic Scholar
Inhibition of efflux pumps in methicillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina.
C. Ramalhete, Gabriella Spengler, A. Martins, Marta Martins +4 more
2011International Journal of Antimicrobial Agents85 citations
Semantic Scholar
P-glycoprotein and membrane roles in multidrug resistance.
Ricardo J. Ferreira, D. D. dos Santos, Maria-José U. Ferreira
2015Future Medicinal Chemistry82 citations
Semantic Scholar
Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages.
Xuan Luo, David Pires, J. Aínsa, Begoña Gracia +4 more
2013Journal of Ethnopharmacology71 citations
Semantic Scholar
Antibacterial activity of some African medicinal plants used traditionally against infectious diseases
A. Madureira, C. Ramalhete, S. Mulhovo, A. Duarte +1 more
2012Pharmaceutical Biology71 citations Open access
Semantic Scholar
Isoflavones as Apoptosis Inducers in Human Hepatoma HuH‐7 Cells
T. A. Mansoor, R. Ramalho, Xuan Luo, C. Ramalhete +2 more
2011Phytotherapy Research71 citations Open access
Semantic Scholar
Enhancing macrocyclic diterpenes as multidrug-resistance reversers: structure-activity studies on jolkinol D derivatives.
Mariana A. Reis, Ricardo J. Ferreira, Maria M. M. Santos, D. D. dos Santos +2 more
2013Journal of Medicinal Chemistry66 citations
Semantic Scholar
Multidrug resistance reversal and apoptosis induction in human colon cancer cells by some flavonoids present in citrus plants.
O. Wesołowska, J. Wiśniewski, K. Środa-Pomianek, Aleksandra Bielawska-Pohl +5 more
2012Journal of Natural Products64 citations
Semantic Scholar
Toward a Better Pharmacophore Description of P-Glycoprotein Modulators, Based on Macrocyclic Diterpenes from Euphorbia Species
Ricardo J. Ferreira, D. D. dos Santos, Maria-José U. Ferreira, R. Guedes
2011Journal of Chemical Information and Modeling60 citations
Semantic Scholar
Structure-function relationships in ABCG2: insights from molecular dynamics simulations and molecular docking studies
Ricardo J. Ferreira, Cátia A. Bonito, M. N. Cordeiro, Maria-José U. Ferreira +1 more
2017Scientific Reports59 citations Open access
Semantic Scholar
Induction of apoptosis in HuH-7 cancer cells by monoterpene and beta-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegans.
T. A. Mansoor, R. Ramalho, S. Mulhovo, C. Rodrigues +1 more
2009Bioorganic & Medicinal Chemistry Letters59 citations
Semantic Scholar
New antimalarials with a triterpenic scaffold from Momordica balsamina.
C. Ramalhete, Dinora Lopes, S. Mulhovo, J. Molnár +2 more
2010Bioorganic & Medicinal Chemistry55 citations
Semantic Scholar
New potent P-glycoprotein modulators with the cucurbitane scaffold and their synergistic interaction with doxorubicin on resistant cancer cells.
C. Ramalhete, J. Molnár, S. Mulhovo, V. Rosário +1 more
2009Bioorganic & Medicinal Chemistry49 citations
Semantic Scholar
Jatrophane diterpenes and cancer multidrug resistance - ABCB1 efflux modulation and selective cell death induction.
Mariana A. Reis, O. Ahmed, Gabriella Spengler, J. Molnár +2 more
2016Phytomedicine45 citations Open access
Semantic Scholar
Jatrophane diterpenes from Euphorbia mellifera and their activity as P-glycoprotein modulators on multidrug-resistant mouse lymphoma and human colon adenocarcinoma cells.
I. Valente, Mariana A. Reis, N. Duarte, Julianna Serly +2 more
2012Journal of Natural Products44 citations
Semantic Scholar
Cucurbitane-type triterpenoids from the African plant Momordica balsamina.
C. Ramalhete, T. A. Mansoor, S. Mulhovo, J. Molnár +1 more
2009Journal of Natural Products43 citations Open access
Semantic Scholar
Monoterpene bisindole alkaloids, from the African medicinal plant Tabernaemontana elegans, induce apoptosis in HCT116 human colon carcinoma cells.
T. A. Mansoor, P. Borralho, S. Dewanjee, S. Mulhovo +2 more
2013Journal of Ethnopharmacology42 citations
Semantic Scholar
Terpenoids from Euphorbia pedroi as Multidrug-Resistance Reversers.
Ricardo J. Ferreira, Annamária Kincses, M. Gajdács, Gabriella Spengler +3 more
2018Journal of Natural Products40 citations
Semantic Scholar
Euphorbia and Momordica metabolites for overcoming multidrug resistance
Maria-José U. Ferreira, N. Duarte, Mariana A. Reis, A. Madureira +1 more
2014Phytochemistry Reviews40 citations
Semantic Scholar
Alkaloids in Future Drug Discovery
Maria-José U. Ferreira
2022Molecules38 citations Open access
Semantic Scholar
Dregamine and tabernaemontanine derivatives as ABCB1 modulators on resistant cancer cells.
Angela Paterna, Annamária Kincses, Gabriella Spengler, S. Mulhovo +2 more
2017European journal of medicinal chemistry38 citations Open access
Semantic Scholar
Improving the MDR reversal activity of 6,17-epoxylathyrane diterpenes.
C. Vieira, N. Duarte, Mariana A. Reis, Gabriella Spengler +3 more
2014Bioorganic & Medicinal Chemistry38 citations Open access
Semantic Scholar
Apoptosis inducing activity of benzophenanthridine-type alkaloids and 2-arylbenzofuran neolignans in HCT116 colon carcinoma cells.
T. A. Mansoor, P. Borralho, Xuan Luo, S. Mulhovo +2 more
2013Phytomedicine38 citations
Semantic Scholar
Triterpenoids as inhibitors of erythrocytic and liver stages of Plasmodium infections.
C. Ramalhete, Filipa P. da Cruz, Dinora Lopes, S. Mulhovo +3 more
2011Bioorganic & Medicinal Chemistry38 citations
Semantic Scholar
Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives.
V. Cabral, Xuan Luo, Elisabete Junqueira, S. S. Costa +5 more
2015Phytomedicine36 citations Open access
Semantic Scholar
Antibacterial benzofuran neolignans and benzophenanthridine alkaloids from the roots of Zanthoxylum capense.
Xuan Luo, L. Pedro, V. Milić, S. Mulhovo +3 more
2012Planta Medica35 citations
Semantic Scholar
Diterpenes from Euphorbia piscatoria: Synergistic Interaction of Lathyranes with Doxorubicin on Resistant Cancer Cells
Mariana A. Reis, Angela Paterna, Andreia Mónico, J. Molnár +2 more
2014Planta Medica33 citations
Semantic Scholar
Stilbenes as multidrug resistance modulators and apoptosis inducers in human adenocarcinoma cells.
O. Wesołowska, J. Wiśniewski, Aleksandra Bielawska-Pohl, M. Paprocka +4 more
2010Anticancer Research33 citations
Semantic Scholar
Reversing cancer multidrug resistance: insights into the efflux by ABC transports from in silico studies
Ricardo J. Ferreira, Maria-José U. Ferreira, D. D. dos Santos
201531 citations
Semantic Scholar
Toxocara canis: potential activity of natural products against second-stage larvae in vitro and in vivo.
Mariana A. Reis, Alcione Trinca, Maria-José U. Ferreira, Ana R Monsalve-Puello +1 more
2010Experimental parasitology31 citations
Semantic Scholar
Epoxylathyrol Derivatives: Modulation of ABCB1-Mediated Multidrug Resistance in Human Colon Adenocarcinoma and Mouse T-Lymphoma Cells.
A. M. Matos, Mariana A. Reis, N. Duarte, Gabriella Spengler +2 more
2015Journal of Natural Products30 citations
Semantic Scholar
Optimizing the flavanone core toward new selective nitrogen-containing modulators of ABC transporters.
Ricardo J. Ferreira, Rafael Baptista, Alexis Moreno, P. G. Madeira +5 more
2018Future Medicinal Chemistry29 citations
Semantic Scholar
Monoterpene indole alkaloid azine derivatives as MDR reversal agents.
Angela Paterna, Ruttiros Khonkarn, S. Mulhovo, Alexis Moreno +4 more
2018Bioorganic & Medicinal Chemistry28 citations Open access
Semantic Scholar
Monoterpene indole alkaloid hydrazone derivatives with apoptosis inducing activity in human HCT116 colon and HepG2 liver carcinoma cells.
Angela Paterna, P. Borralho, Sofia E. Gomes, S. Mulhovo +2 more
2015Bioorganic & Medicinal Chemistry Letters28 citations Open access
Semantic Scholar
Colon adenocarcinoma multidrug resistance reverted by Euphorbia diterpenes: structure-activity relationships and pharmacophore modeling.
Mariana A. Reis, Ricardo J. Ferreira, Julianna Serly, N. Duarte +4 more
2012Anti-Cancer Agents in Medicinal Chemistry28 citations
Semantic Scholar
Cleistochlamys kirkii chemical constituents: Antibacterial activity and synergistic effects against resistant Staphylococcus aureus strains.
F. Pereira, A. Madureira, Shirley A R Sancha, S. Mulhovo +3 more
2016Journal of Ethnopharmacology27 citations Open access
Semantic Scholar
Triterpenoids from Momordica balsamina: Reversal of ABCB1-mediated multidrug resistance.
C. Ramalhete, S. Mulhovo, J. Molnár, Maria-José U. Ferreira
2016Bioorganic & Medicinal Chemistry27 citations Open access
Semantic Scholar
In vivo evaluation of isolated triterpenes and semi-synthetic derivatives as antimalarial agents.
L. F. Silva, C. Ramalhete, K. L. Nogueira, S. Mulhovo +2 more
2015European journal of medicinal chemistry27 citations Open access
Semantic Scholar
QSAR studies of macrocyclic diterpenes with P-glycoprotein inhibitory activity.
Inês J. Sousa, Maria-José U. Ferreira, J. Molnár, M. Fernandes
2013European Journal of Pharmaceutical Sciences27 citations Open access
Semantic Scholar
Phenolic compounds as selective antineoplasic agents against multidrug-resistant human cancer cells.
N. Duarte, H. Lage, M. Abrantes, Maria-José U. Ferreira
2010Planta Medica27 citations
Semantic Scholar
Momordica balsamina: phytochemistry and pharmacological potential of a gifted species
C. Ramalhete, Bruno M. F. Gonçalves, F. Barbosa, N. Duarte +1 more
2022Phytochemistry Reviews26 citations Open access
Semantic Scholar
Do drugs have access to the P-glycoprotein drug-binding pocket through gates?
Ricardo J. Ferreira, Maria-José U. Ferreira, D. D. dos Santos
2015Journal of Chemical Theory and Computation26 citations
Semantic Scholar
Dual-stage triterpenoids from an African medicinal plant targeting the malaria parasite.
C. Ramalhete, Filipa P. da Cruz, S. Mulhovo, Inês J. Sousa +3 more
2014Bioorganic & Medicinal Chemistry26 citations Open access
Semantic Scholar
Assessing the Stabilization of P‐Glycoprotein’s Nucleotide‐Binding Domains by the Linker, Using Molecular Dynamics
Ricardo J. Ferreira, Maria-José U. Ferreira, D. D. dos Santos
2013Molecular Informatics26 citations
Semantic Scholar
Anti-inflammatory guaiane-type sesquiterpenes from the fruits of Pittosporum undulatum.
Sofia Mendes, T. A. Mansoor, A. Rodrigues, J. Armas +1 more
2013Phytochemistry26 citations
Semantic Scholar
Karavilagenin C derivatives as antimalarials.
C. Ramalhete, Dinora Lopes, J. Molnár, S. Mulhovo +2 more
2011Bioorganic & Medicinal Chemistry26 citations
Semantic Scholar
BBIT20 inhibits homologous DNA repair with disruption of the BRCA1–BARD1 interaction in breast and ovarian cancer
L. Raimundo, Angela Paterna, J. Calheiros, J. Ribeiro +10 more
2021British Journal of Pharmacology25 citations Open access
Semantic Scholar
Alkylated monoterpene indole alkaloid derivatives as potent P-glycoprotein inhibitors in resistant cancer cells.
David S. P. Cardoso, Annamária Kincses, Márta Nové, Gabriella Spengler +4 more
2020European journal of medicinal chemistry25 citations Open access
Semantic Scholar

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S. Mulhovo×23
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S. Mulhovo — researcher profile on SciRah
J. Molnár×16
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Ricardo J. Ferreira×12
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Ricardo J. Ferreira — researcher profile on SciRah
D. D. dos Santos×12
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C. Ramalhete — researcher profile on SciRah

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A. Madureira — researcher profile on SciRah