Case Report: An Incidental Finding of Fahr's Disease in a Patient with Hypochondria
Courtland R Samuelsa b c d✉, Javed L Khannia b c d, Patricio S Espinosaa b c d, Kory Barkleya b c d, Mishah Azhara b c d
- aEmergency Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
- bInternal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
- cNeurology, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA
- dNeurology, Marcus Neuroscience Institute, Boca Raton, USA
- ✉Corresponding author
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Abstract
Idiopathic basal ganglia calcification (IBGC), commonly referred to as Fahr's disease, is a rare neurological disorder characterized by the abnormal, symmetrical, and bilateral calcification of the basal ganglia and other brain regions. Patients typically present in their forties and fifties with various neurologic and/or psychiatric symptoms, including movement disorders, Parkinsonism, psychosis, and depression. The pathophysiology of this disease is not completely understood; however, several gene mutations have been identified in the pathogenesis of Fahr's disease. These mutations display an autosomal dominant inheritance pattern. Furthermore, the regional phenotypic expression of calcifications differs greatly from patient to patient, as do their clinical presentations. Here, we describe a patient who presented with psychiatric manifestations and imaging consistent with Fahr's disease.
TL;DRA patient who presented with psychiatric manifestations and imaging consistent with Fahr’s disease is described, which indicates that the pathophysiology of this disease is not completely understood. (Semantic Scholar)