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Samar Abdulkhalek · SciRah

Researcher profile · Semantic Scholar

Samar Abdulkhalek

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Samar Abdulkhalek — researcher profile on SciRah

h-index: 15
Works: 25
Citations: 897

Most-cited papers

Association of TCF7L2 polymorphism with diabetes mellitus, metabolic syndrome, and markers of beta cell function and insulin resistance in a population-based sample of Emirati subjects.
Hussein Saadi, N. Nagelkerke, S. Carruthers, S. Benedict +4 more
2008Diabetes Research and Clinical Practice96 citations
Semantic Scholar
Neu1 Sialidase and Matrix Metalloproteinase-9 Cross-talk Is Essential for Toll-like Receptor Activation and Cellular Signaling*
Samar Abdulkhalek, S. R. Amith, Susan L. Franchuk, Preethi Jayanth +7 more
2011Journal of Biological Chemistry94 citations Open access
Semantic Scholar
A novel epidermal growth factor receptor-signaling platform and its targeted translation in pancreatic cancer.
Alanna Gilmour, Samar Abdulkhalek, Timothy S. W. Cheng, Farah G. Alghamdi +5 more
2013Cellular Signalling93 citations Open access
Semantic Scholar
A novel insulin receptor-signaling platform and its link to insulin resistance and type 2 diabetes.
Farah G. Alghamdi, Merry Guo, Samar Abdulkhalek, N. Crawford +2 more
2014Cellular Signalling87 citations Open access
Semantic Scholar
EGFR kinase activity is required for TLR4 signaling and the septic shock response
S. Chattopadhyay, Manoj Veleeparambil, Darshana Poddar, Samar Abdulkhalek +3 more
2015EMBO Reports76 citations Open access
Semantic Scholar
Neu1 sialidase and matrix metalloproteinase-9 cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 and -9 activation, cellular signaling and pro-inflammatory responses.
Samar Abdulkhalek, M. Szewczuk
2013Cellular Signalling68 citations Open access
Semantic Scholar
Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance
Leah O'Shea, Samar Abdulkhalek, S. Allison, R. Neufeld +1 more
2014OncoTargets and Therapy67 citations Open access
Semantic Scholar
G-protein coupled receptor agonists mediate Neu1 sialidase and matrix metalloproteinase-9 cross-talk to induce transactivation of TOLL-like receptors and cellular signaling.
Samar Abdulkhalek, Merry Guo, S. R. Amith, Preethi Jayanth +1 more
2012Cellular Signalling65 citations
Semantic Scholar
Detection of Neu1 sialidase activity in regulating Toll-like receptor activation.
S. R. Amith, Preethi Jayanth, T. Finlay, Susan L. Franchuk +3 more
2010Journal of Visualized Experiments52 citations Open access
Semantic Scholar
Oseltamivir phosphate monotherapy ablates tumor neovascularization, growth, and metastasis in mouse model of human triple-negative breast adenocarcinoma
Fiona Haxho, S. Allison, Farah G. Alghamdi, Lacey Brodhagen +4 more
2014Breast Cancer43 citations Open access
Semantic Scholar
Transcriptional factor snail controls tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma
Samar Abdulkhalek, O. Geen, Lacey Brodhagen, Fiona Haxho +6 more
2014Clinical and Translational Medicine34 citations Open access
Semantic Scholar
Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo
T. Finlay, Samar Abdulkhalek, Alanna Gilmour, C. Guzzo +5 more
2010Glycoconjugate Journal34 citations
Semantic Scholar
A novel G-protein-coupled receptor-signaling platform and its targeted translation in human disease
Samar Abdulkhalek, Michael Hrynyk, M. Szewczuk
201330 citations Open access
Semantic Scholar
Therapeutic designed poly (lactic-co-glycolic acid) cylindrical oseltamivir phosphate-loaded implants impede tumor neovascularization, growth and metastasis in mouse model of human pancreatic carcinoma
Michael Hrynyk, J. P. Ellis, Fiona Haxho, S. Allison +4 more
2015Drug Design, Development and Therapy25 citations Open access
Semantic Scholar
CONSTITUTIVELY BOUND EGFR-MEDIATED TYROSINE PHOSPHORYLATION OF TLR9 IS REQUIRED FOR ITS ABILITY TO SIGNAL
Manoj Veleeparambil, Darshana Poddar, Samar Abdulkhalek, Patricia M. Kessler +3 more
2018Journal of Immunology22 citations Open access
Semantic Scholar
Novel Therapeutic Target Critical for SARS-CoV-2 Infectivity and Induction of the Cytokine Release Syndrome
William W. Harless, Beth Lewis, B. Qorri, Samar Abdulkhalek +1 more
2023Cells5 citations Open access
Semantic Scholar
Medicinal and anti-oxidant effects of Bitter Melon (Momordica charantia) in the treatment of diabetic cardiomyopathy
Manal Smail, F. Howarth, Samar Abdulkhalek, A. M. Ismail +6 more
20203 citations
Semantic Scholar
Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology
R. L. Schnaar, James C. Paulson, Matthew S Macauley, Corwin M. Nycholat +496 more
20122 citations
Semantic Scholar
Mechanisms of Diabetes Mellitus-Induced Sudden Cardiac Death
Manal Smail, F. Howarth, Jaipaul Singh, Sunil Rupee +6 more
2020Sudden Cardiac Death1 citations Open access
Semantic Scholar
A Discrete Study on Stochastic Epidemic Models with the Optimal Control Policies and Its Analysis
M. Jamali, Mohammed Abushohada, Samar Abdulkhalek, Shahla Shafique +1 more
2022Journal of Hunan University Natural Sciences0 citations Open access
Semantic Scholar
Abstract LB-273: Molecular targeting Neu1 with oseltamivir phosphate abrogates tumor neovascularization, growth, and metastasis in mouse model of human triple-negative breast cancer
M. Szewczuk, Fiona Haxho, S. Allison, Farah G. Alghamdi +4 more
20150 citations
Semantic Scholar
Abstract LB-274: Transcriptional factor Snail and MMP-9 signaling axis amplifies Neu1-MMP-9 crosstalk on EGF receptor to regulate tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma
M. Szewczuk, Samar Abdulkhalek, O. Geen, Lacey Brodhagen +6 more
20150 citations
Semantic Scholar
Therapeutic targeting of neu1 sialidase with oseltamivir phosphate (Tamiflu ® ) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance
Leah O'Shea, Samar Abdulkhalek, S. Allison, R. Neufeld +1 more
20140 citations
Semantic Scholar
Central Lancashire Online Knowledge (CLoK)
Manal Smail, Samar Abdulkhalek, Ram Singh, Jaipaul Singh +7 more
0 citations
Semantic Scholar

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M. Szewczuk×17
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M. Szewczuk — researcher profile on SciRah
Farah G. Alghamdi×7
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Farah G. Alghamdi — researcher profile on SciRah
S. Allison×7
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R. Neufeld×7
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S. R. Amith — researcher profile on SciRah

Preethi Jayanth×5

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Leah O'Shea — researcher profile on SciRah

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Fiona Haxho — researcher profile on SciRah

Alanna Gilmour×4

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Alanna Gilmour — researcher profile on SciRah

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Merry Guo — researcher profile on SciRah

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T. Finlay — researcher profile on SciRah