Researcher profile · Semantic Scholar

Vivian Chua

h-index: 11
Works: 35
Citations: 442

Most-cited papers

Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma
Vivian Chua, Dominic Lapadula, Clinita Randolph, J. Benovic +2 more
2017Molecular Cancer Research69 citations Open access
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Co-targeting HGF-cMET signaling with MEK inhibitors in metastatic uveal melanoma
Hanyin Cheng, Vivian Chua, Connie Liao, Timothy J. Purwin +5 more
2017Molecular Cancer Therapeutics63 citations Open access
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Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma
Vivian Chua, M. Orloff, Jessica L. F. Teh, T. Sugase +9 more
2019EMBO Molecular Medicine54 citations Open access
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Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma
G. Ambrosini, Catherine Do, B. Tycko, Ronald B. Realubit +6 more
2019Cancer Research43 citations Open access
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BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
Anna Han, Timothy J. Purwin, Nelisa Bechtel, Connie Liao +7 more
2020Oncogene42 citations Open access
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Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma
Jessica L. F. Teh, Timothy J. Purwin, Anna Han, Vivian Chua +8 more
2020Molecular Cancer Therapeutics27 citations Open access
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Novel therapeutic strategies and targets in advanced uveal melanoma
Vivian Chua, A. Aplin
2017Current Opinion in Oncology23 citations
Semantic Scholar
The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019)
Vivian Chua, J. Mattei, Anna Han, L. Johnston +5 more
2020Clinical Cancer Research21 citations Open access
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Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma
Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Vivian Chua +5 more
2022Molecular Cancer Research19 citations Open access
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Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma
Anna Han, Vivian Chua, Usman Baqai, Timothy J. Purwin +8 more
2022Oncogene17 citations Open access
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The AMP‐dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma
Vivian Chua, Anna Han, Nelisa Bechtel, Timothy J. Purwin +4 more
2021Pigment Cell & Melanoma Research16 citations
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Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth
Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin +16 more
2023Cancers9 citations Open access
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Activity of ABCG2 Is Regulated by Its Expression and Localization in DHT and Cyclopamine‐Treated Breast Cancer Cells
Vivian Chua, I. Larma, J. Harvey, M. Thomas +1 more
2016Journal of Cellular Biochemistry8 citations
Semantic Scholar
Metabolic inhibition induces pyroptosis in uveal melanoma
Scott D Varney, Dan A. Erkes, Glenn L. Mersky, Manal U Mustafa +5 more
2024Molecular Cancer Research7 citations
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Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress
Vivian Chua, Melisa Lopez-Anton, Mizue Terai, Ryota Tanaka +14 more
2024Science Signaling7 citations
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Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma
Usman Baqai, Alison M. Kurimchak, Isabella V Trachtenberg, Timothy J. Purwin +11 more
2023Journal of Biological Chemistry7 citations Open access
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Multi‐omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma
Usman Baqai, Timothy J. Purwin, Vivian Chua, Anna Han +5 more
2022The FASEB Journal3 citations
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Elevated NR2F1 underlies the persistence of invasive disease after treatment of BRAF-mutant melanoma
Manoela Tiago, Timothy J. Purwin, Casey D. Stefanski, R. O. da Silva +17 more
2025Journal of Clinical Investigation2 citations Open access
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Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP1 signaling in dormant disseminated uveal melanoma
Rama Kadamb, M. Anton, Timothy J. Purwin, Lornella Seeneevassen +11 more
2024bioRxiv2 citations Open access
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Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
Anna Han, Timothy J. Purwin, Nelisa Bechtel, Connie Liao +7 more
2021Oncogene2 citations Open access
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Correction: Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma.
G. Ambrosini, Catherine Do, B. Tycko, Ronald B. Realubit +6 more
2025Cancer Research1 citations
Semantic Scholar
Abstract A009: NR2F1 inhibits Gaq/11-YAP-TAZ signaling and limits reactivation of uveal melanoma disseminated cancer cells via induction of dormancy
Rama Kadamb, M. Anton, Vivian Chua, Timothy J. Purwin +3 more
2023Cancer Research1 citations
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Abstract 715: Regulation of the ABCG2 drug efflux transporter in breast cancer cells
Vivian Chua, J. Harvey, J. Bentel
20151 citations
Semantic Scholar
Diacylglycerol Kinase Eta as a Novel Target in NRAS Mutant Melanoma
Haley P Wilson, Casey D. Stefanski, Signe Caksa, Glenn L. Mersky +6 more
2026Pigment Cell & Melanoma Research0 citations Open access
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Editor's Note: Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma.
G. Ambrosini, Catherine Do, B. Tycko, Ronald B. Realubit +6 more
2026Cancer Research0 citations
Semantic Scholar
TPI and GAPDH Interact with Rad9, Linking Glycolytic Enzymes to Cancer
Vivian Chua, J. M. X. Yip, Melody T. K. Cho, Sumi Z. Q. Lin +8 more
2026International Journal of Molecular Sciences0 citations Open access
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Abstract C048: Intrapatient heterogeneity and targeting microenvironment protection mechanisms in melanoma metastasis
Haley P Wilson, Glenn L. Mersky, Jelan I. Haj, Jessica L. F. Teh +13 more
2024Cancer Research0 citations
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Abstract 6942: Single cell resolution of intrapatient drug resistance mechanisms in metastatic melanoma
Haley P Wilson, Glenn L. Mersky, Jelan I. Haj, Jessica L. F. Teh +9 more
2024Cancer Research0 citations
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Abstract A005: The aged tumor microenvironment influences tolerance to targeted therapy via NR2F1 overexpression in BRAF-mutant melanoma
Manoela Tiago, Timothy J. Purwin, Mitchell E. Fane, Yash Chhabra +13 more
2023Cancer Research0 citations
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Abstract 860: Identifying mechanisms associated with slow proliferation of BAP1 mutant uveal melanoma cells
Vivian Chua, Usman Baqai, Timothy J. Purwin, Angela Jeon +2 more
2022Cancer Research0 citations
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Abstract 167: Multiomics profiling of BAP1 loss in uveal melanoma
Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Vivian Chua +2 more
2021Bioinformatics and Systems Biology0 citations
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Abstract B27: Identification of uveal melanoma disseminated cancer cell dormancy mechanisms
Melisa Lopez-Anton, E. Farias, Vivian Chua, Mizue Terai +6 more
20200 citations
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Abstract 5852: FGF2 confers resistance to novel BET inhibitors in metastatic uveal melanoma
Vivian Chua, Timothy J. Purwin, Connie Liao, A. Aplin
2018Experimental and Molecular Therapeutics0 citations
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Cover Image, Volume 117, Number 10, October 2016
Vivian Chua, I. Larma, J. Harvey, M. Thomas +1 more
2016Journal of Cellular Biochemistry0 citations Open access
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Regulation of gene expression by the androgen receptor and hedgehog pathways in breast cancer cells
Vivian Chua
20150 citations
Semantic Scholar

Takami Sato

×9

Nelisa Bechtel×9

Usman Baqai×9

Connie Liao×7

Jessica L. F. Teh×7

Mizue Terai×6

Jelan I. Haj×6

J. Harbour×5