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Alessandro Zarpellon · SciRah

Researcher profile · Semantic Scholar

Alessandro Zarpellon

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Alessandro Zarpellon — researcher profile on SciRah

h-index: 16
Works: 33
Citations: 953

Most-cited papers

Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.
Lea Scheppke, Eric A. Murphy, Alessandro Zarpellon, Jennifer J. Hofmann +7 more
2012Blood142 citations Open access
Semantic Scholar
PLD3 and PLD4 are single stranded acid exonucleases that regulate endosomal nucleic acid sensing
A. Gavin, De-Li Huang, C. Huber, A. Mårtensson +23 more
2018Nature Immunology129 citations Open access
Semantic Scholar
The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.
Cong-Lei Li, Siavash Piran, Ping-Guo Chen, Sean Lang +12 more
2011Journal of Clinical Investigation94 citations Open access
Semantic Scholar
Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4
Z. Kaplan, Alessandro Zarpellon, I. Alwis, Yu-Ping Yuan +5 more
2015Nature Communications75 citations Open access
Semantic Scholar
Variation pattern of sperm quality traits in two gobies with alternative mating tactics
L. Locatello, A. Pilastro, R. Deana, Alessandro Zarpellon +1 more
200774 citations Open access
Semantic Scholar
Type I interferon is a therapeutic target for virus-induced lethal vascular damage
R. Baccala, M. Welch, R. González‐Quintial, K. Walsh +9 more
2014Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics
M. Oldstone, Brian C. Ware, Lucy E. Horton, M. Welch +4 more
2018Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Binding of α-thrombin to surface-anchored platelet glycoprotein Ibα sulfotyrosines through a two-site mechanism involving exosite I
Alessandro Zarpellon, R. Celikel, J. Roberts, R. McClintock +5 more
2011Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Unraveling Mechanism and Significance of Thrombin Binding to Platelet Glycoprotein Ib
Z. Ruggeri, Alessandro Zarpellon, J. Roberts, R. McClintock +2 more
2010Thrombosis and Haemostasis43 citations Open access
Semantic Scholar
Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia
T. Kanaji, M. Vo, Sachiko Kanaji, Alessandro Zarpellon +9 more
2018Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice
N. Yokota, Alessandro Zarpellon, S. Chakrabarty, Vladimir Y. Bogdanov +7 more
2014Journal of Thrombosis and Haemostasis35 citations Open access
Semantic Scholar
Genetic deletion of platelet Glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis
E. Koltsova, P. Sundd, Alessandro Zarpellon, Hui Ouyang +4 more
2014Thrombosis and Haemostasis28 citations Open access
Semantic Scholar
Platelet glycoprotein V spatio-temporally controls fibrin formation
S. Beck, Patricia Öftering, Ren-Hao Li, K. Hemmen +11 more
2023Nature Cardiovascular Research27 citations Open access
Semantic Scholar
Serotonin (5-HT) Transport in Human Platelets is Modulated by Src-Catalysed Tyr-Phosphorylation of the Plasma Membrane Transporter SERT
Alessandro Zarpellon, A. Donella-Deana, A. Folda, L. Turetta +2 more
2008Cellular Physiology and Biochemistry25 citations Open access
Semantic Scholar
Humanized GPIbα-von Willebrand factor interaction in the mouse.
Sachiko Kanaji, J. Orje, T. Kanaji, Y. Kamikubo +10 more
2018Blood Advances21 citations Open access
Semantic Scholar
Regulation of Serotonin Transport in Human Platelets by Tyrosine Kinase Syk
M. Pavanetto, Alessandro Zarpellon, C. Borgo, A. Donella-Deana +1 more
2011Cellular Physiology and Biochemistry17 citations Open access
Semantic Scholar
Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection
Y. Morodomi, Sachiko Kanaji, B. Sullivan, Alessandro Zarpellon +8 more
2022Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
Inhibitory effect by new monocyclic 4-alkyliden-beta-lactam compounds on human platelet activation
M. Pavanetto, Alessandro Zarpellon, D. Giacomini, P. Galletti +5 more
2007Platelets8 citations
Semantic Scholar
The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse
Sachiko Kanaji, Y. Morodomi, H. Weiler, Alessandro Zarpellon +3 more
2022Haematologica6 citations Open access
Semantic Scholar
Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe
X. Xu, C. Spring, L. Ju, Yiming Wang +20 more
20143 citations Open access
Semantic Scholar
Abstract 499: Development of a Novel Antithrombotic Therapy Targeting Platelet GPIbα: Assessment of Anfibatide In Vitro and in Phase I Clinical Trial
Yan Hou, A. Reheman, Benjamin X. Li, Xiang-Rong Dai +16 more
20143 citations
Semantic Scholar
Human PAR1 expressed on mouse platelets contributes to hemostasis and arterial occlusion
Sachiko Kanaji, Alessandro Zarpellon, Roberto Aiolfi, Y. Morodomi +5 more
2025bioRxiv2 citations Open access
Semantic Scholar
Pathogen Reduced Cryoprecipitated Fibrinogen Complex (IFC) and Cryoprecipitated AHF Contain Von Willebrand Factor with Comparable Binding to Collagen and Support Shear-Induced Platelet Thrombus Formation
S. Yegneswaran, Alessandro Zarpellon, J. Orje, Michelle Gatmaitan +3 more
2023Blood2 citations Open access
Semantic Scholar
Expression of Functional Human Proteinase Activated Receptor (PAR)-1 on Mouse Platelets
Alessandro Zarpellon, T. Kanaji, Sachiko Kanaji, Y. Morodomi +1 more
20172 citations
Semantic Scholar
Humanized Von Willebrand Factor-Glycoprotein Ibα Interaction in Mouse Models of Hemostasis and Thrombosis
Sachiko Kanaji, J. Orje, Y. Kamikubo, T. Kanaji +7 more
20161 citations
Semantic Scholar
Extracellular Tyrosyl-tRNA Synthetase Is a Potent Stimulator of Thrombocytopoiesis
Sachiko Kanaji, T. Kanaji, M. Vo, Alessandro Zarpellon +6 more
20160 citations
Semantic Scholar
Platelet Aggregation and Fibrin Deposition: The Yin and Yang of Thrombin Activity Regulation By Platelet Glycoprotein Ibα
Alessandro Zarpellon, P. Marchese, A. Zampolli, G. Mendolicchio +1 more
20140 citations
Semantic Scholar
Abstract 58: Delayed Atherosclerosis in a Mouse Model of Bernard-Soulier Syndrome is Independent of Glycoprotein Ibα Extracytoplasmic Domain Deficiency
E. Koltsova, P. Sundd, Alessandro Zarpellon, Z. Ruggeri +1 more
2014Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
GPIbα As a Selective Bidirectional Modulator Of α-Thrombin Prothrombotic Functions Influencing Fibrin Deposition and PAR-Dependent Platelet Activation
Alessandro Zarpellon, A. Zampolli, P. Marchese, J. Roberts +2 more
20130 citations
Semantic Scholar
Structural and Functional Evidence on the Role of Sulfated Tyrosine Residues In Glycoprotein Ib Binding to α-Thrombin Exosites
Alessandro Zarpellon, R. Celikel, R. McClintock, J. Roberts +4 more
20100 citations
Semantic Scholar
Mechanism and Functional Consequences of Thrombin Binding to Glycoprotein Ib.
Alessandro Zarpellon, A. Zampolli, L. Mendolicchio, J. Roberts +1 more
20090 citations
Semantic Scholar
Platelet interactions with a-thrombin and serotonin
Alessandro Zarpellon
20080 citations
Semantic Scholar
Mechanism of α-Thrombin Binding to Platelet Glycoprotein Ibα
Alessandro Zarpellon, R. McClintock, J. Roberts, Z. Ruggeri
20080 citations
Semantic Scholar

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Z. Ruggeri×27
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Z. Ruggeri — researcher profile on SciRah
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T. Kanaji — researcher profile on SciRah
Sachiko Kanaji×8
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Sachiko Kanaji — researcher profile on SciRah
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G. Mendolicchio

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