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Jan Diekmann · SciRah

Researcher profile · Semantic Scholar

Jan Diekmann

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Jan Diekmann — researcher profile on SciRah

h-index: 15
Works: 30
Citations: 7,242

Most-cited papers

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
U. Şahin, E. Derhovanessian, Matthias Miller, B. Kloke +46 more
2017Nature2,299 citations
Semantic Scholar
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
L. Kranz, M. Diken, H. Haas, S. Kreiter +24 more
2016Nature1,605 citations
Semantic Scholar
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
S. Kreiter, Mathias Vormehr, N. van de Roemer, M. Diken +11 more
2015Nature1,200 citations Open access
Semantic Scholar
Exploiting the mutanome for tumor vaccination.
John C. Castle, S. Kreiter, Jan Diekmann, Martin Löwer +12 more
2012Cancer Research769 citations Open access
Semantic Scholar
A vaccine targeting mutant IDH1 induces antitumour immunity
Theresa Schumacher, L. Bunse, S. Pusch, F. Sahm +23 more
2014Nature685 citations
Semantic Scholar
Local delivery of mRNA-encoding cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models
Christian Hotz, T. Wagenaar, F. Gieseke, D. Bangari +33 more
2021Science Translational Medicine196 citations
Semantic Scholar
Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial
Juanita S. Lopez, T. Powles, F. Braiteh, L. Siu +76 more
2025Nature Medicine104 citations Open access
Semantic Scholar
FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.
S. Kreiter, M. Diken, A. Selmi, Jan Diekmann +6 more
2011Cancer Research77 citations Open access
Semantic Scholar
Lack of effects on female fertility and prenatal and postnatal offspring development in rats with BNT162b2, a mRNA-based COVID-19 vaccine
C. Bowman, M. Bouressam, S. Campion, G. D. Cappon +6 more
2021Reproductive Toxicology68 citations Open access
Semantic Scholar
mTOR Inhibition Improves Antitumor Effects of Vaccination with Antigen-Encoding RNA
M. Diken, S. Kreiter, F. Vascotto, A. Selmi +5 more
2013Cancer immunology research42 citations
Semantic Scholar
Toxicological Assessments of a Pandemic COVID-19 Vaccine—Demonstrating the Suitability of a Platform Approach for mRNA Vaccines
C. Rohde, C. Lindemann, Michael A. Giovanelli, Rani S. Sellers +7 more
2023Vaccines39 citations Open access
Semantic Scholar
Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside
Valesca Boisguérin, John C. Castle, M. Loewer, Jan Diekmann +5 more
2014British Journal of Cancer38 citations Open access
Semantic Scholar
Human CD4+ T Cells Displaying Viral Epitopes Elicit a Functional Virus-Specific Memory CD8+ T Cell Response1
Eleni Adamopoulou, Jan Diekmann, E. Tolosa, Gaby Kuntz +3 more
2007Journal of Immunology30 citations
Semantic Scholar
Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibody
Hayat Bähr-Mahmud, U. Ellinghaus, Christiane R. Stadler, Leyla Fischer +14 more
2023Oncoimmunology24 citations Open access
Semantic Scholar
Processing of Two Latent Membrane Protein 1 MHC Class I Epitopes Requires Tripeptidyl Peptidase II Involvement1
Jan Diekmann, Eleni Adamopoulou, O. Beck, G. Rauser +6 more
2009Journal of Immunology21 citations Open access
Semantic Scholar
mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models
N. Agrawal, Louis S. Ates, Stefan A Schille, Anuhar Chaturvedi +7 more
2025bioRxiv12 citations Open access
Semantic Scholar
Erratum: Mutant MHC class II epitopes drive therapeutic immune responses to cancer
S. Kreiter, Mathias Vormehr, N. van de Roemer, M. Diken +11 more
2015Nature12 citations Open access
Semantic Scholar
Abstract CT032: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles for potent cancer immunotherapy in patients with malignant melanoma
R. Jabulowsky, C. Loquai, M. Diken, L. Kranz +28 more
20167 citations
Semantic Scholar
Abstract LB-130: Combinatorial treatment with intratumoral cytokine mRNAs results in high frequency of tumor rejection and development of anti-tumor immunity across a range of preclinical cancer models
T. Wagenaar, Christian Hotz, F. Gieseke, Hui Cao +28 more
2018Immunology5 citations
Semantic Scholar
Abstract CT020: MERIT: introducing individualized cancer vaccines for the treatment of TNBC - a phase I trial
S. Heesch, V. Bukur, Janina Buck, Jan Diekmann +23 more
20165 citations
Semantic Scholar
Abstract CT022: IVAC® MUTANOME - A first-in-human phase I clinical trial targeting individual mutant neoantigens for the treatment of melanoma
Matthias Miller, C. Loquai, B. Kloke, S. Attig +30 more
20164 citations
Semantic Scholar
Abstract CT202: IVAC MUTANOME: Individualized vaccines for the treatment of cancer
B. Kloke, C. Britten, C. Loquai, Martin Löwer +32 more
20154 citations
Semantic Scholar
Abstract CT034: A first-in-human phase I/II clinical trial assessing novel mRNA-lipoplex nanoparticles for potent melanoma immunotherapy
R. Jabulowsky, C. Loquai, J. Utikal, J. Hassel +26 more
20173 citations
Semantic Scholar
Abstract B041: A novel nanoparticular formulated tetravalent RNA cancer vaccine for treatment of patients with malignant melanoma
R. Jabulowsky, C. Loquai, M. Diken, L. Kranz +28 more
20163 citations
Semantic Scholar
Abstract A110: Mutant MHC class II epitopes drive therapeutic immune responses to cancer
Mathias Vormehr, S. Kreiter, N. van de Roemer, M. Diken +8 more
20162 citations
Semantic Scholar
Abstract CT201: The Mutanome Engineered RNA Immuno-Therapy (MERIT) project
S. Heesch, C. Britten, V. Bukur, Janina Buck +26 more
20151 citations
Semantic Scholar
P2.06 Exploiting The Mutanome for Tumor Vaccination
John C. Castle, S. Kreiter, Jan Diekmann, Martin Löwer +12 more
20121 citations Open access
Semantic Scholar
Messenger RNA delivery of a dual CD25/CD122 affinity-tuned IL-2 variant prolongs exposure and potentiates antitumor T cell immunity
Mathias Vormehr, L. Kranz, A. Muik, S. Fellermeier-Kopf +7 more
2026Science Advances0 citations Open access
Semantic Scholar
Abstract A004: Systemic RNA vaccines: Connecting effective cancer immunotherapy with antiviral defense mechanisms
L. Kranz, M. Diken, H. Haas, S. Kreiter +24 more
20160 citations
Semantic Scholar
This information is current as Peptidase II Involvement Tripeptidyl 1 MHC Class I Epitopes Requires Processing of Two Latent Membrane Protein
Jan Diekmann, Eleni Adamopoulou, O. Beck, G. Rauser +6 more
20090 citations
Semantic Scholar

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