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D. Thorborn · SciRah

Researcher profile · Semantic Scholar

D. Thorborn

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D. Thorborn — researcher profile on SciRah

h-index: 8
Works: 22
Citations: 2,192

Most-cited papers

HLA-B*5701 screening for hypersensitivity to abacavir.
S. Mallal, E. Phillips, G. Carosi, J. Molina +14 more
2008New England Journal of Medicine1,655 citations Open access
Semantic Scholar
Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial.
S. Staszewski, P. Keiser, J. Montaner, F. Raffi +13 more
2001Journal of the American Medical Association (JAMA)292 citations
Semantic Scholar
Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility
A. Hughes, WR Spreen, M. Mosteller, L. Warren +10 more
2008The Pharmacogenomics Journal84 citations Open access
Semantic Scholar
PREDICT‐1 (CNA106030): the first powered, prospective trial of pharmacogenetic screening to reduce drug adverse events
S. Hughes, A. Hughes, Cindy H. Brothers, W. Spreen +1 more
2008Pharmaceutical statistics57 citations
Semantic Scholar
New Genetic Predictors for Abacavir Tolerance in HLA-B*57:01 Positive Individuals
R. Pavlos, Pooja Deshpande, A. Chopra, Shay Leary +16 more
2020Human Immunology22 citations Open access
Semantic Scholar
PREDICT-1: a novel randomised prospective study to determine the clinical utility of HLA-B*5701 screening to reduce abacavir hypersensitivity in HIV-1 infected subjects
S. Mallal, E. Phillips, G. Carosi, J. Molina +10 more
200717 citations
Semantic Scholar
Intracellular cytokines may model immunoregulation of abacavir hypersensitivity in HIV-infected subjects.
D. King, S. Tomkins, A. Waters, P. Easterbrook +5 more
2005Journal of Allergy and Clinical Immunology16 citations
Semantic Scholar
Early induction of leukemia inhibitor factor (LIF) in acute HIV-1 infection
Annelie Tjernlund, Babilonia Barqasho, P. Nowak, S. Kinloch +5 more
2006AIDS (London)15 citations Open access
Semantic Scholar
Polyamine and thiol metabolism in Trypanosoma granulosum: similarities with Trypanosoma cruzi.
Calli Mastri, D. Thorborn, A. J. Davies, Mark R. Ariyanayagam +1 more
2001Biochemical and Biophysical Research Communications - BBRC8 citations
Semantic Scholar
Genetic factors predicting abacavir hypersensitivity and tolerance in HLA-B*5701 positive individuals
E. Phillips, D. Nolan, D. Thorborn, Malinda Schaefer +9 more
20087 citations
Semantic Scholar
Experiments with growth of the eel trypanosome, Trypanosoma granulosum Laveran & Mesnil, 1902, in semi-defined and defined media
A. J. Davies, C. Mastri, D. Thorborn, D. Mackintosh
19957 citations
Semantic Scholar
Genetic factors predicting abacavir hypersensitivty and tolerance in HLA-B*5701 positive individuals: Combined analysis from PREDICT-1, SHAPE and a multinational study
D. Nolan, D. Thorborn, M. Shaefer, R. Laird +5 more
20085 citations
Semantic Scholar
Abacavir induced hypersensitivity in HIV infected individuals is associated with an increased frequency of Th0 T cells
A. Vyakarnam, D. King, Mark J. Boaz, A. Waters +4 more
20003 citations
Semantic Scholar
HLA-B*5701 Taqman assay for abacavir sensitivity: Application to PREDICT-1 trial
T. Bugawan, W. Isoda, C. Mano, A. Blair +3 more
20081 citations
Semantic Scholar
163-P: HLA-B*5701 Taqman assay for abacavir sensitivity; application to PREDICT-1 trials
T. Bugawan, W. Isoda, C. Mano, A. Blair +3 more
20081 citations
Semantic Scholar
Predict-1: A novel randomised prospective study to determine the clinical utility of prognostic screening for HLA-B*5701
S. Hughes, K. Parry-Billings, N. Givens, D. Wong +6 more
20071 citations
Semantic Scholar
Uptake of putrescine by Trypanosoma granulosum.
Calli Mastri, Francesca Rytlewski, D. Thorborn, A. J. Davies +1 more
1998Biochemical Society Transactions1 citations
Semantic Scholar
ULTRASTRUCTURE OF CULTURE FORMS OF THE EEL TRYPANOSOME, TRYPANOSOMA GRANULOSUM LAVERAN& MESNIL, 1902, EXPOSED TO POLYAMINE BIOSYNTHESIS INHIBITORS
A. J. Davies, D. Thorborn, C. Mastri, P. Daszak
20100 citations
Semantic Scholar
S 376 Biochemical Society Transactions ( 1 998 ) 26 90
Calcott Ma, F. Rytlewski, D. Thorborn, A. J. Davies +1 more
20090 citations
Semantic Scholar
HLA-B*5701 screening reduces abacavir hypersensitivity reactions (ABC HSR): Multiple lines of evidence to establish a new standard of care
P. Wannamaker, S. Mallal, E. Phillips, B. Young +3 more
20080 citations
Semantic Scholar
PIN40 AN AUDIT OF HLA-B570I SCREENING METHODS AND COSTS IN THE UNITED KINGDOM
F. Jackson, D. Thorborn, P. Maroudas
20070 citations Open access
Semantic Scholar
The role of polyamines and related metabolites in the growth and morphology of two piscine trypanosomes
D. Thorborn
19960 citations
Semantic Scholar

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S. Mallal×8
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S. Mallal — researcher profile on SciRah
E. Phillips×7
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A. Hughes×6
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D. Nolan×5
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D. Nolan — researcher profile on SciRah

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A. J. Davies — researcher profile on SciRah

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S. Hughes — researcher profile on SciRah

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M. Shaefer — researcher profile on SciRah

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I. James — researcher profile on SciRah

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G. Carosi — researcher profile on SciRah

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J. Molina — researcher profile on SciRah

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C. Workman — researcher profile on SciRah

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