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A. Roseborough · SciRah

Researcher profile · Semantic Scholar

A. Roseborough

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A. Roseborough — researcher profile on SciRah

h-index: 9
Works: 24
Citations: 293

Most-cited papers

White matter hyperintensities and longitudinal cognitive decline in cognitively normal populations and across diagnostic categories: A meta‐analysis, systematic review, and recommendations for future study harmonization
A. Roseborough, Lorenzo Saad, Maren Goodman, L. Cipriano +2 more
2022Alzheimer's & Dementia75 citations
Semantic Scholar
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction.
A. Roseborough, Y. Zhu, L. Zhao, S. Laviolette +2 more
2023Neurobiology of Disease40 citations Open access
Semantic Scholar
Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model
A. Roseborough, S. Myers, R. Khazaee, Y. Zhu +5 more
2023Journal of Neuroinflammation35 citations Open access
Semantic Scholar
Mechanisms and Biomarker Potential of Extracellular Vesicles in Stroke
Nikita Ollen-Bittle, A. Roseborough, Wenxuan Wang, Jeng-Liang D. Wu +1 more
2022Biology28 citations Open access
Semantic Scholar
Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates
A. Roseborough, K. Langdon, R. Hammond, L. Cipriano +3 more
2020NeuroImage: Clinical25 citations Open access
Semantic Scholar
TSPO PET detects acute neuroinflammation but not diffuse chronically activated MHCII microglia in the rat
Nassir U. Al-Khishman, Qi Qi, A. Roseborough, A. Levit +5 more
2020EJNMMI Research18 citations Open access
Semantic Scholar
Microvessel stenosis, enlarged perivascular spaces, and fibrinogen deposition are associated with ischemic periventricular white matter hyperintensities
A. Roseborough, Berk Rasheed, Y. Jung, K. Nishimura +6 more
2021Brain Pathology15 citations Open access
Semantic Scholar
Nanoscale flow cytometry‐based quantification of blood‐based extracellular vesicle biomarkers distinguishes MCI and Alzheimer's disease
Thamara Dayarathna, A. Roseborough, Janice Gomes, R. Khazaee +14 more
2024Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Regional Lipid Expression Abnormalities Identified Using MALDI IMS Correspond to MRI-Defined White Matter Hyperintensities within Post-mortem Human Brain Tissues.
William Pinsky, Aaron Harris, A. Roseborough, Wenxuan Wang +5 more
2021Analytical Chemistry10 citations
Semantic Scholar
Editorial Focus: White matter-associated microglia (WAMs) represent an important link between aging, white matter disease and microglial activity
A. Roseborough, V. Jaremek, S. Whitehead
2021GeroScience8 citations Open access
Semantic Scholar
White Matter Degeneration-A Treatable Target?
A. Roseborough, V. Hachinski, S. Whitehead
2020JAMA Neurology8 citations
Semantic Scholar
Connecting cellular mechanisms and extracellular vesicle cargo in traumatic brain injury
Nikita Ollen-Bittle, A. Roseborough, Wen-Xuan Wang, Jeng-Liang D. Wu +1 more
2023Neural Regeneration Research7 citations Open access
Semantic Scholar
Using microglia-derived extracellular vesicles to capture diversity of microglial activation phenotypes following neurological injury
A. Roseborough, Nikita Ollen-Bittle, Shawn N. Whitehead
2023Neural Regeneration Research6 citations Open access
Semantic Scholar
Inflammation and Cognitive Decline: A Population‐Based Cohort Study Among Aging Adults With Atrial Fibrillation
Danielle Marion, Zhe Li, A. Roseborough, Shawn N. Whitehead +6 more
2025Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease3 citations Open access
Semantic Scholar
Age‐ and sex‐dependent differences in cognitive decline in rat models of Alzheimer’s disease
S. J. Myers, A. Roseborough, B. L. Allman, Shawn N. Whitehead
2023Alzheimer's & Dementia2 citations Open access
Semantic Scholar
Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space
Nikita Ollen-Bittle, Isabella Boesgaard, A. Roseborough, Meaghan Frank +4 more
2026Brain Pathology1 citations Open access
Semantic Scholar
Increased circulating TREM2+ microglial extracellular vesicles in aged APP/PS1 Alzheimer's disease rats
S. J. Myers, Manoj Reddy Medapati, B. L. Allman, Stephen H. Pasternak +2 more
2025bioRxiv1 citations Open access
Semantic Scholar
Microglial morphology reflects cognitive status in the aging rat brain
S. J. Myers, A. Roseborough, Cristian X. Bayona, Carlangelo Carrese +2 more
2025bioRxiv1 citations Open access
Semantic Scholar
Investigating White Matter Inflammatory Cells and their Relationship with Beta‐Amyloid in Alzheimer's Disease
Miranda J. Wysoczanski, A. Roseborough, S. J. Myers, Shawn N. Whitehead
2022The FASEB Journal1 citations
Semantic Scholar
Microvessel Stenosis and Density Analysis of Post Mortem WMH Detected Using Ultra High Field MRI in Aging, Cerebrovascular and Alzheimer Disease
A. Roseborough, K. Langdon, R. Hammond, S. Pasternak +2 more
2019The FASEB Journal1 citations
Semantic Scholar
Characterizing a hallmark of glymphatic insufficiency: Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index and perivascular space
Nikita Ollen-Bittle, Isabella Boesgaard, A. Roseborough, Meaghan Frank +4 more
2025bioRxiv0 citations Open access
Semantic Scholar
Glymphatic perivascular clearance and extracellular vesicles: neuroimaging & blood‐based biomarkers in mild cognitive impairment
Ramírez-Emiliano Joel, L. A. Woods, Jeng-Liang D. Wu, S. Berberian +7 more
2025Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Unique cognitive trajectories associated with inflammatory markers of blood‐brain barrier permeability in atrial fibrillation: An analysis of the Cardiovascular Health Study Cohort
Danielle Marion, Zhe Li, A. Roseborough, Shawn N. Whitehead +8 more
2023Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Plasma based assessment of extracellular vesicles biomarkers in Alzheimer’s Disease
Thamara Dayarathna, A. Roseborough, Janice Gomes, R. Khazaee +3 more
2023Alzheimer's & Dementia0 citations Open access
Semantic Scholar

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