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J. Humphrey · SciRah

Researcher profile · Semantic Scholar

J. Humphrey

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J. Humphrey — researcher profile on SciRah

h-index: 72
Works: 398
Citations: 22K

Most-cited papers

Arterial Stiffness and Cardiovascular Risk in Hypertension.
P. Boutouyrie, P. Chowienczyk, J. Humphrey, G. Mitchell
2021Circulation Research596 citations Open access
Semantic Scholar
Growth and remodelling of living tissues: perspectives, challenges and opportunities
D. Ambrosi, M. B. Ben Amar, C. Cyron, A. DeSimone +3 more
2019Journal of the Royal Society Interface241 citations Open access
Semantic Scholar
Vascular Mechanobiology: Homeostasis, Adaptation, and Disease
J. Humphrey, Martin A. Schwartz
2021Annual Review of Biomedical Engineering200 citations Open access
Semantic Scholar
Smooth muscle cell reprogramming in aortic aneurysms
Pei-Yu Chen, Ling-Feng Qin, Guangxin Li, José Malagón-López +21 more
2020Cell Stem Cell193 citations Open access
Semantic Scholar
Non-invasive Inference of Thrombus Material Properties with Physics-Informed Neural Networks
Minglang Yin, Xiaoning Zheng, J. Humphrey, George Em Karniadakis
2020Computer Methods in Applied Mechanics and Engineering188 citations Open access
Semantic Scholar
Mechanisms of Vascular Remodeling in Hypertension.
J. Humphrey
2020American Journal of Hypertension166 citations Open access
Semantic Scholar
Spontaneous reversal of stenosis in tissue-engineered vascular grafts
Joseph D. Drews, Victoria K. Pepper, C. Best, Jason M. Szafron +33 more
2020Science Translational Medicine116 citations Open access
Semantic Scholar
Chronic mTOR activation induces a degradative smooth muscle cell phenotype.
Guangxin Li, Mo Wang, Alexander W. Caulk, Nicholas A. Cilfone +19 more
2020Journal of Clinical Investigation84 citations Open access
Semantic Scholar
Simulating progressive intramural damage leading to aortic dissection using DeepONet: an operator–regression neural network
Minglang Yin, Ehsan Ban, B. Rego, Enrui Zhang +3 more
2021Journal of the Royal Society Interface70 citations Open access
Semantic Scholar
Integrating blood cell mechanics, platelet adhesive dynamics and coagulation cascade for modelling thrombus formation in normal and diabetic blood
Alireza Yazdani, Yixiang Deng, He Li, E. Javadi +6 more
2021Journal of the Royal Society Interface69 citations Open access
Semantic Scholar
Mechanical homeostasis in tissue equivalents: a review
J. Eichinger, Lea J. Haeusel, D. Paukner, R. Aydin +2 more
2021Biomechanics and Modeling in Mechanobiology65 citations Open access
Semantic Scholar
A three-dimensional phase-field model for multiscale modeling of thrombus biomechanics in blood vessels
Xiaoning Zheng, Alireza Yazdani, He Li, J. Humphrey +1 more
2020PLoS Comput. Biol.61 citations Open access
Semantic Scholar
Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth
Kevin M. Blum, J. Zbinden, A. Ramachandra, Stephanie E. Lindsey +33 more
2022Communications Medicine55 citations Open access
Semantic Scholar
From Transcript to Tissue: Multiscale Modeling from Cell Signaling to Matrix Remodeling
Linda Irons, M. Latorre, J. Humphrey
2021Annals of Biomedical Engineering51 citations Open access
Semantic Scholar
Cell signaling model for arterial mechanobiology
Linda Irons, J. Humphrey
2020PLoS Comput. Biol.50 citations Open access
Semantic Scholar
A computational framework for modeling cell–matrix interactions in soft biological tissues
J. Eichinger, Maximilian J. Grill, I. Kermani, R. Aydin +3 more
2021Biomechanics and Modeling in Mechanobiology49 citations Open access
Semantic Scholar
Developmental Origins of Mechanical Homeostasis in the Aorta
Sae-Il Murtada, Y. Kawamura, Guangxin Li, M. Schwartz +2 more
2020Developmental Dynamics49 citations Open access
Semantic Scholar
Mechanics-driven mechanobiological mechanisms of arterial tortuosity
D. Weiss, C. Cavinato, Authia Gray, A. Ramachandra +3 more
2020Science Advances46 citations Open access
Semantic Scholar
Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients
Erica L. Schwarz, John M. Kelly, Kevin M. Blum, K. Hor +10 more
2021npj Regenerative Medicine45 citations Open access
Semantic Scholar
Evolving Structure-Function Relations during Aortic Maturation and Aging Revealed by Multiphoton Microscopy
C. Cavinato, Sae-Il Murtada, Alexia Rojas, J. Humphrey
2021Mechanisms of Ageing and Development44 citations Open access
Semantic Scholar
Excessive Adventitial Stress Drives Inflammation-Mediated Fibrosis in Hypertensive Aortic Remodeling in Mice
B. Spronck, M. Latorre, Mo Wang, S. Mehta +10 more
2021Journal of the Royal Society Interface39 citations Open access
Semantic Scholar
Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency
Hualong Bai, N. Sadaghianloo, J. Gorecka, Shirley Liu +7 more
2020Science Translational Medicine38 citations Open access
Semantic Scholar
Neural operator learning of heterogeneous mechanobiological insults contributing to aortic aneurysms
S. Goswami, David S. Li, B. Rego, M. Latorre +2 more
2022Journal of the Royal Society Interface37 citations Open access
Semantic Scholar
Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta
C. Cavinato, Minghao Chen, D. Weiss, M. J. Ruíz-Rodríguez +2 more
2021Frontiers in Cardiovascular Medicine35 citations Open access
Semantic Scholar
Numerical knockouts–In silico assessment of factors predisposing to thoracic aortic aneurysms
M. Latorre, J. Humphrey
2020PLoS Comput. Biol.34 citations Open access
Semantic Scholar
Fast, Rate-Independent, Finite Element Implementation of a 3D Constrained Mixture Model of Soft Tissue Growth and Remodeling
M. Latorre, J. Humphrey
2020bioRxiv34 citations Open access
Semantic Scholar
A Fluid-Solid-Growth Solver for Cardiovascular Modeling
Erica L. Schwarz, M. Pfaller, Jason M. Szafron, M. Latorre +4 more
2023Computer Methods in Applied Mechanics and Engineering33 citations Open access
Semantic Scholar
Multimodality Imaging-Based Characterization of Regional Material Properties in a Murine Model of Aortic Dissection
M. Bersi, V. A. Acosta-Santamaría, Karl Marback, Paolo Di Achille +4 more
2020Scientific Reports33 citations Open access
Semantic Scholar
Maladaptive aortic remodeling in hypertension associates with dysfunctional smooth muscle contractility.
A. Korneva, J. Humphrey
2019American Journal of Physiology. Heart and Circulatory Physiology31 citations Open access
Semantic Scholar
Homeostatic, Non-Canonical Role of Macrophage Elastase in Vascular Integrity
Mani Salarian, Mean Ghim, Jakub Toczek, Jin-Ah Han +10 more
2023Circulation Research29 citations Open access
Semantic Scholar
Comparative Study of Human and Murine Aortic Biomechanics and Hemodynamics in Vascular Aging
S. Hopper, Federica Cuomo, J. Ferruzzi, N. Burris +3 more
2021Frontiers in Physiology29 citations Open access
Semantic Scholar
Effects of Braiding Parameters on Tissue Engineered Vascular Graft Development
J. Zbinden, Kevin M. Blum, A. Berman, A. Ramachandra +16 more
2020Advanced Healthcare Materials28 citations
Semantic Scholar
Quantitative not qualitative histology differentiates aneurysmal from nondilated ascending aortas and reveals a net gain of medial components
Sameh Yousef, Nana P. Matsumoto, Issam Dabe, M. Mori +11 more
2021Scientific Reports27 citations Open access
Semantic Scholar
Multi-view digital image correlation systems for in vitro testing of arteries from mice to humans
K. Genovese, P. Badel, C. Cavinato, B. Pierrat +3 more
2021Experimental mechanics27 citations Open access
Semantic Scholar
Computational Modeling Predicts Immuno-Mechanical Mechanisms of Maladaptive Aortic Remodeling in Hypertension
M. Latorre, M. Bersi, J. Humphrey
2019International Journal of Engineering Science27 citations Open access
Semantic Scholar
Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms.
J. Hansen, J. Galatioto, Cristina I. Caescu, P. Arnaud +13 more
2019JCI Insight25 citations Open access
Semantic Scholar
Understanding Pulmonary Autograft Remodeling After the Ross Procedure: Stick to the Facts
L. van Hoof, P. Verbrugghe, E. Jones, J. Humphrey +3 more
2022Frontiers in Cardiovascular Medicine23 citations Open access
Semantic Scholar
Roles of mTOR in thoracic aortopathy understood by complex intracellular signaling interactions
Ana C. Estrada, Linda Irons, B. Rego, Guangxin Li +2 more
2021PLoS Comput. Biol.23 citations Open access
Semantic Scholar
A computational bio-chemo-mechanical model of in vivo tissue-engineered vascular graft development.
R. Khosravi, A. Ramachandra, Jason M. Szafron, D. Schiavazzi +2 more
2020Integrative Biology23 citations Open access
Semantic Scholar
Computer-Controlled Biaxial Bioreactor for Investigating Cell-Mediated Homeostasis in Tissue Equivalents.
J. Eichinger, D. Paukner, Jason M. Szafron, R. Aydin +2 more
2020Journal of Biomechanical Engineering23 citations Open access
Semantic Scholar
Predicting and understanding arterial elasticity from key microstructural features by bidirectional deep learning.
Kevin Linka, C. Cavinato, J. Humphrey, C. Cyron
2022Acta Biomaterialia22 citations Open access
Semantic Scholar
Intracellular Signaling Control of Mechanical Homeostasis in the Aorta
Linda Irons, Ana C. Estrada, J. Humphrey
2022Biomechanics and Modeling in Mechanobiology21 citations Open access
Semantic Scholar
Complementary roles of mechanotransduction and inflammation in vascular homeostasis
M. Latorre, B. Spronck, J. Humphrey
2021Proceedings of the Royal Society A21 citations Open access
Semantic Scholar
Tissue Engineering of Vascular Grafts: A Case Report From Bench to Bedside and Back
Thomas Breuer, Michael Jimenez, J. Humphrey, T. Shinoka +1 more
2023Arteriosclerosis, Thrombosis and Vascular Biology20 citations Open access
Semantic Scholar
Role of Axl in target organ inflammation and damage due to hypertensive aortic remodeling.
Wei Chen, Justin P. Van Beusecum, Liang Xiao, David M. Patrick +8 more
2022American Journal of Physiology. Heart and Circulatory Physiology20 citations Open access
Semantic Scholar
Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging
B. Spronck, J. Ferruzzi, C. Bellini, Alexander W. Caulk +2 more
2020Journal of Hypertension20 citations Open access
Semantic Scholar
mTOR inhibition prevents angiotensin II–induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice
Changshun He, Bo Jiang, Mo Wang, P. Ren +9 more
2022JCI Insight19 citations Open access
Semantic Scholar
Uncertainty quantification in subject-specific estimation of local vessel mechanical properties
B. Rego, D. Weiss, M. Bersi, J. Humphrey
2021bioRxiv19 citations Open access
Semantic Scholar
Differential Propensity of Dissection Along the Aorta
Ehsan Ban, C. Cavinato, J. Humphrey
2021Biomechanics and Modeling in Mechanobiology18 citations Open access
Semantic Scholar
Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth
Sumeda Nandadasa, Jason M. Szafron, Vai S. Pathak, Sae-Il Murtada +13 more
2020bioRxiv18 citations Open access
Semantic Scholar

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