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Geoffrey Pires · SciRah

Researcher profile · Semantic Scholar

Geoffrey Pires

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Geoffrey Pires — researcher profile on SciRah

h-index: 13
Works: 38
Citations: 1,147

Most-cited papers

Phosphorylated tau interactome in the human Alzheimer’s disease brain
Eleanor Drummond, Geoffrey Pires, Claire MacMurray, M. Askenazi +5 more
2020Brain : a journal of neurology325 citations Open access
Semantic Scholar
Proteomic Differences in Amyloid Plaques in Rapidly Progressive and Sporadic Alzheimer’s Disease
Eleanor Drummond, Shruti D. Nayak, Arline Faustin, Geoffrey Pires +10 more
2017Acta Neuropathologica206 citations Open access
Semantic Scholar
Compilation of reported protein changes in the brain in Alzheimer’s disease
M. Askenazi, Tomas Kavanagh, Geoffrey Pires, B. Ueberheide +2 more
2023Nature Communications149 citations Open access
Semantic Scholar
The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome
Eleanor Drummond, Tomas Kavanagh, Geoffrey Pires, Mitchell Martá-Ariza +6 more
2022Acta Neuropathologica Communications128 citations Open access
Semantic Scholar
Proteomic Differences in the Hippocampus and Cortex of Epilepsy Brain Tissue
Geoffrey Pires, D. Leitner, Eleanor Drummond, Evgeny Kanshin +8 more
2020bioRxiv61 citations Open access
Semantic Scholar
Isolation of Amyloid Plaques and Neurofibrillary Tangles from Archived Alzheimer’s Disease Tissue Using Laser-Capture Microdissection for Downstream Proteomics
Eleanor Drummond, Shruti D. Nayak, Geoffrey Pires, B. Ueberheide +1 more
2018Methods in molecular biology45 citations
Semantic Scholar
Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis
L. Moro, Daniele Simoneschi, Emma Kurz, A. Arbini +14 more
2020Nature Cell Biology40 citations Open access
Semantic Scholar
Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathies
Geoffrey Pires, S. McElligott, Shiron Drusinsky, G. Halliday +3 more
2019Acta Neuropathologica Communications38 citations Open access
Semantic Scholar
Similar brain proteomic signatures in Alzheimer’s disease and epilepsy
D. Leitner, Geoffrey Pires, Tomas Kavanagh, Evgeny Kanshin +5 more
2024Acta Neuropathologica35 citations Open access
Semantic Scholar
Proteomics and Transcriptomics of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Patients
D. Leitner, J. D. Mills, Geoffrey Pires, Arline Faustin +21 more
2021Neurology29 citations Open access
Semantic Scholar
The influence of APOEε4 on the pTau interactome in sporadic Alzheimer’s disease
Manon Thierry, Jackeline Ponce, Mitchell Martá-Ariza, M. Askenazi +7 more
2024Acta Neuropathologica28 citations Open access
Semantic Scholar
Differences in the cerebral amyloid angiopathy proteome in Alzheimer’s disease and mild cognitive impairment
D. Leitner, Tomas Kavanagh, Evgeny Kanshin, Kaleah Balcomb +7 more
2024Acta Neuropathologica25 citations Open access
Semantic Scholar
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder
A. de Thonel, Johanna K. Ahlskog, Kévin Daupin, Véronique Dubreuil +34 more
2022Nature Communications20 citations Open access
Semantic Scholar
Compilation of all known protein changes in the human Alzheimer’s disease brain
M. Askenazi, Tomas Kavanagh, Geoffrey Pires, B. Ueberheide +2 more
2023bioRxiv6 citations Open access
Semantic Scholar
Use of Affinity Purification-Mass Spectrometry to Identify Phosphorylated Tau Interactors in Alzheimer's Disease.
Geoffrey Pires, B. Ueberheide, T. Wisniewski, Eleanor Drummond
2023Methods in molecular biology6 citations
Semantic Scholar
It takes more than tau to tangle: using proteomics to determine how phosphorylated tau mediates toxicity in neurodegenerative diseases
Geoffrey Pires, Eleanor Drummond
2021Neural Regeneration Research2 citations Open access
Semantic Scholar
P4‐530: PHOSPHORYLATED TAU INTERACTOME IN THE HUMAN ALZHEIMER'S DISEASE BRAIN
Eleanor Drummond, Geoffrey Pires, Claire MacMurray, M. Askenazi +4 more
2019Alzheimer's & Dementia2 citations Open access
Semantic Scholar
CBP/EP300-dependent acetylation and stabilization of HSF2 are compromised in the rare disorder, Rubinstein-Taybi syndrome
A. de Thonel, Johanna K. Ahlskog, R. Abane, Geoffrey Pires +30 more
2018bioRxiv2 citations Open access
Semantic Scholar
Proteomic similarities in Alzheimer’s disease and epilepsy brains highlight the important role of tau
Geoffrey Pires, D. Leitner, Evgeny Kanshin, M. Askenazi +5 more
20201 citations Open access
Semantic Scholar
P1‐082: THERAPEUTICALLY EFFICACIOUS ANTI‐β‐SHEET MONOCLONAL DOES NOT INDUCE MICROHEMORRHAGES OR INFLAMMATION IN TGSWDI AD MICE WITH EXTENSIVE VASCULAR AMYLOID, INCREASING CHANCES OF SAFE TRANSLATABILITY
F. Goñi, Geoffrey Pires, Mitchell Martá-Ariza, T. Wisniewski
2019Alzheimer's & Dementia1 citations Open access
Semantic Scholar
O4‐01‐06: SECERNIN‐1 IS A NOVEL PHOSPHORYLATED TAU BINDING PROTEIN THAT ACCUMULATES IN ALZHEIMER'S DISEASE AND NOT IN OTHER TAUOPATHIES
Geoffrey Pires, F. Prelli, Glenda Halliday, S. McElligott +3 more
2019Alzheimer's & Dementia1 citations
Semantic Scholar
O5‐04‐02: Altered Protein Expression in Amyloid Plaques in Rapidly Progressive Alzheimer's Disease
Eleanor Drummond, Shruti D. Nayak, Arline Faustin, Geoffrey Pires +8 more
20161 citations Open access
Semantic Scholar
Sequential accumulation of phosphorylated tau species in early Alzheimer's disease
Arline Faustin, Aysha Y. G. Strobbe, Kaleah Balcomb, Evgeny Kanshin +7 more
2025Alzheimer's & Dementia0 citations
Semantic Scholar
The influence of APOEε4 on the pTau interactome in sporadic Alzheimer’s disease
Manon Thierry, Jackeline Ponce, Mitchell Marta Ariza, M. Askenazi +7 more
2024Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Basic Science and Pathogenesis.
D. Leitner, Geoffrey Pires, Tomas Kavanagh, Evgeny Kanshin +5 more
2024Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Basic Science and Pathogenesis.
Manon Thierry, Jackeline Ponce, Mitchell Marta Ariza, M. Askenazi +7 more
2024Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Similar brain proteomic signatures in Alzheimer’s disease and epilepsy
D. Leitner, Geoffrey Pires, Tomas Kavanagh, Evgeny Kanshin +5 more
2024Alzheimer's & Dementia0 citations Open access
Semantic Scholar
The pTau interactome in sporadic Alzheimer’s disease across APOE genotypes
Manon Thierry, Jackeline Ponce, Mitchell Marta Ariza, M. Askenazi +7 more
2023Alzheimer's & Dementia0 citations
Semantic Scholar
Author Correction: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder
A. de Thonel, Johanna K. Ahlskog, Kévin Daupin, Véronique Dubreuil +34 more
2023Nature Communications0 citations Open access
Semantic Scholar
The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome
Eleanor Drummond, Tomas Kavanagh, Geoffrey Pires, Mitchell Martá-Ariza +6 more
2022Acta Neuropathologica Communications0 citations Open access
Semantic Scholar
Monoclonal GW‐23B7 removes Aβ‐pathologic oligomers and produces cognitive rescue without toxicity in old TGSWDI AD model mice with advanced pathology
F. Goñi, Geoffrey Pires, Thomas S. Genovese, T. Wisniewski
2020Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Proteomic and Transcriptomic Analyses of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Cases
D. Leitner, J. D. Mills, Geoffrey Pires, Arline Faustin +21 more
2020bioRxiv0 citations Open access
Semantic Scholar
The amyloid plaque proteome in different subtypes of Alzheimer’s disease
Eleanor Drummond, Geoffrey Pires, Evgeny Kanshin, M. Askenazi +2 more
20200 citations Open access
Semantic Scholar
P1‐155: DIFFERENCES IN THE AMYLOID PLAQUE PROTEOME IN DOWN SYNDROME
Eleanor Drummond, Valentin Berdah, Shruti D. Nayak, Geoffrey Pires +2 more
2019Alzheimer's & Dementia0 citations
Semantic Scholar
P2‐170: SECERNIN‐1 IS A NOVEL EARLY MARKER OF NEUROFIBRILLARY TANGLES IN ALZHEIMER'S DISEASE
Eleanor Drummond, Geoffrey Pires, F. Prelli, S. McElligott +2 more
20180 citations
Semantic Scholar
IMMUNE-REGULATED METABOLIC PATHWAYANALYSIS IN AT8-POSITIVE NEURONS USING LASER CAPTURE MICROSCOPY SECERNIN-1 IS A NOVEL EARLY MARKER OF NEUROFIBRILLARY TANGLES IN ALZHEIMER’S DISEASE
Geoffrey Pires, F. Prelli, S. McElligott, Shiron Drusinsky +1 more
20180 citations
Semantic Scholar
P1‐243: SECERNIN‐1: A NOVEL AMYLOID PLAQUE AND OLIGOMER SPECIES ASSOCIATED PROTEIN
F. Prelli, Eleanor Drummond, Geoffrey Pires, Shruti D. Nayak +2 more
20180 citations
Semantic Scholar
The Use of Localized Proteomics to Understand the Pathogenesis of Alzheimer's Disease
Geoffrey Pires
0 citations
Semantic Scholar

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Eleanor Drummond×23
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M. Askenazi×19
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B. Ueberheide×18
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Evgeny Kanshin×16
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T. Wisniewski — researcher profile on SciRah

Shruti D. Nayak×12

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Arline Faustin×12

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D. Leitner — researcher profile on SciRah

Tomas Kavanagh×9

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Beatrix M. Ueberheide×8

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Beatrix M. Ueberheide — researcher profile on SciRah

Thomas Wisniewski×7

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Thomas Wisniewski — researcher profile on SciRah

Eleanor Drummond×6

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Eleanor Drummond — researcher profile on SciRah