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S. Schobel · SciRah

Researcher profile · Semantic Scholar

S. Schobel

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S. Schobel — researcher profile on SciRah

h-index: 29
Works: 69
Citations: 6,141

Most-cited papers

A pathophysiological framework of hippocampal dysfunction in ageing and disease
S. Small, S. Schobel, R. Buxton, M. Witter +1 more
2011Nature Reviews Neuroscience961 citations Open access
Semantic Scholar
Maternal immune activation and abnormal brain development across CNS disorders
I. Knuesel, L. Chicha, M. Britschgi, S. Schobel +4 more
2014Nature Reviews Neurology844 citations
Semantic Scholar
Targeting Huntingtin Expression in Patients with Huntington's Disease.
S. Tabrizi, B. Leavitt, G. Landwehrmeyer, E. Wild +18 more
2019New England Journal of Medicine548 citations Open access
Semantic Scholar
Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a pathogenic driver
S. Schobel, Nashid H. Chaudhury, Usman A. Khan, B. Paniagua +7 more
2013Neuron520 citations Open access
Semantic Scholar
Differential Targeting of the CA1 Subfield of the Hippocampal Formation by Schizophrenia and Related Psychotic Disorders
S. Schobel, N. Lewandowski, C. Corcoran, H. Moore +3 more
2009Archives of General Psychiatry380 citations Open access
Semantic Scholar
Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention
J. Lieberman, Ragy R. Girgis, Gary Brucato, Holly Moore +8 more
2018Molecular Psychiatry353 citations Open access
Semantic Scholar
A biological classification of Huntington's disease: the Integrated Staging System.
S. Tabrizi, S. Schobel, E. Gantman, A. Mansbach +12 more
2022Lancet Neurology255 citations Open access
Semantic Scholar
Type III Neuregulin-1 is required for normal sensorimotor gating, memory related behaviors and cortico-striatal circuit components
Ying-Jiun J. Chen, Madeleine A. Johnson, M. Lieberman, Rose E. Goodchild +10 more
2008Journal of Neuroscience206 citations Open access
Semantic Scholar
Cerebral blood flow predicts differential neurotransmitter activity
J. Dukart, Š. Holiga, C. Chatham, P. Hawkins +21 more
2017Scientific Reports199 citations Open access
Semantic Scholar
The relationship of social function to depressive and negative symptoms in individuals at clinical high risk for psychosis
C. Corcoran, D. Kimhy, M. Parrilla-Escobar, V. Cressman +7 more
2010Psychological Medicine158 citations Open access
Semantic Scholar
Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease
L. Byrne, F. Rodrigues, E. Johnson, P. Wijeratne +9 more
2018Science Translational Medicine156 citations Open access
Semantic Scholar
Duration of illness and treatment effects on hippocampal volume in male patients with schizophrenia
M. Chakos, S. Schobel, H. Gu, G. Gerig +3 more
2005British Journal of Psychiatry148 citations Open access
Semantic Scholar
Motor, cognitive, and functional declines contribute to a single progressive factor in early HD
S. Schobel, G. Palermo, P. Auinger, Jeffrey D. Long +12 more
2017Neurology144 citations Open access
Semantic Scholar
Childhood Trauma and Prodromal Symptoms Among Individuals at Clinical High Risk for Psychosis
Judy L. Thompson, Meredith A. Kelly, D. Kimhy, J. Harkavy-Friedman +6 more
2009Schizophrenia Research133 citations Open access
Semantic Scholar
Anterior hippocampal and orbitofrontal cortical structural brain abnormalities in association with cognitive deficits in schizophrenia
S. Schobel, Meredith A. Kelly, C. Corcoran, K. Van Heertum +4 more
2009Schizophrenia Research106 citations Open access
Semantic Scholar
Temporal association of stress sensitivity and symptoms in individuals at clinical high risk for psychosis
J. Devylder, S. Ben-David, S. Schobel, D. Kimhy +2 more
2012Psychological Medicine103 citations Open access
Semantic Scholar
Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington’s disease
F. Rodrigues, L. Byrne, R. Tortelli, E. Johnson +13 more
2020Science Translational Medicine91 citations Open access
Semantic Scholar
Temporal Association of Cannabis Use with Symptoms in Individuals at Clinical High Risk for Psychosis
C. Corcoran, D. Kimhy, Arielle D. Stanford, Shamir A. Khan +8 more
2008Schizophrenia Research87 citations Open access
Semantic Scholar
Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer’s disease
R. Bateman, J. Cummings, S. Schobel, S. Salloway +9 more
2022Alzheimer's Research & Therapy82 citations Open access
Semantic Scholar
Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition
A. Gilani, Muhammad O. Chohan, M. Inan, S. Schobel +10 more
2014Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
Tominersen in Adults with Manifest Huntington's Disease.
P. McColgan, A. Thobhani, L. Boak, S. Schobel +19 more
2023New England Journal of Medicine76 citations Open access
Semantic Scholar
Baseline demographics, clinical features and predictors of conversion among 200 individuals in a longitudinal prospective psychosis-risk cohort
Gary Brucato, Michael D. Masucci, L. Arndt, S. Ben-David +11 more
2017Psychological Medicine72 citations Open access
Semantic Scholar
Test-retest reliability of task-based and resting-state blood oxygen level dependence and cerebral blood flow measures
Š. Holiga, F. Sambataro, Cécile Luzy, G. Greig +6 more
2018bioRxiv71 citations Open access
Semantic Scholar
Huntingtin-Lowering Therapies for Huntington Disease: A Review of the Evidence of Potential Benefits and Risks.
B. Leavitt, Holly B. Kordasiewicz, S. Schobel
2020JAMA Neurology62 citations
Semantic Scholar
A predictive model for conversion to psychosis in clinical high-risk patients
Adam J. Ciarleglio, Gary Brucato, Michael D. Masucci, Rebecca Altschuler +11 more
2018Psychological Medicine54 citations Open access
Semantic Scholar
Anhedonia in the psychosis risk syndrome: associations with social impairment and basal orbitofrontal cortical activity
V. Cressman, S. Schobel, S. Steinfeld, S. Ben-David +4 more
2015npj Schizophrenia41 citations Open access
Semantic Scholar
A Remote Digital Monitoring Platform to Assess Cognitive and Motor Symptoms in Huntington Disease: Cross-sectional Validation Study
F. Lipsmeier, C. Simillion, A. Bamdadian, R. Tortelli +11 more
2022Journal of Medical Internet Research31 citations Open access
Semantic Scholar
Murine Glut-1 transporter haploinsufficiency: postnatal deceleration of brain weight and reactive astrocytosis
Paivi M. Ullner, A. Di Nardo, J. Goldman, S. Schobel +5 more
2009Neurobiology of Disease30 citations Open access
Semantic Scholar
Effects of IONIS-HTTRx in Patients with Early Huntington’s Disease, Results of the First HTT-Lowering Drug Trial (CT.002)
S. Tabrizi, B. Leavitt, Holly B. Kordasiewicz, C. Czech +8 more
2018Neurology29 citations
Semantic Scholar
How high-resolution basal-state functional imaging can guide the development of new pharmacotherapies for schizophrenia.
I. Gaisler-Salomon, S. Schobel, S. Small, S. Rayport
2009Schizophrenia bulletin24 citations Open access
Semantic Scholar
Ranking the Predictive Power of Clinical and Biological Features Associated With Disease Progression in Huntington's Disease
Naghmeh Ghazaleh, R. Houghton, G. Palermo, S. Schobel +2 more
2021Frontiers in Neurology15 citations Open access
Semantic Scholar
Changes in brain activity with tominersen in early-manifest Huntington’s disease
D. Hawellek, P. Garcés, A. Meghdadi, S. Waninger +4 more
2022Brain Communications14 citations Open access
Semantic Scholar
Results and evaluation of a first‐in‐human study of RG7342, an mGlu5 positive allosteric modulator, utilizing Bayesian adaptive methods
S. Sturm, M. Delporte, S. Hadi, S. Schobel +5 more
2018British Journal of Clinical Pharmacology11 citations Open access
Semantic Scholar
Defining Clinically Meaningful Change on the Composite Unified Huntington’s Disease Rating Scale (cUHDRS) (P1.8-043)
D. Trundell, Giuseppe Palermo, S. Schobel, Jeffery D. Long +2 more
2019Neurology10 citations
Semantic Scholar
F23 Validity, reliability, ability to detect change and meaningful within-patient change of the CUHDRS
D. Trundell, G. Palermo, S. Schobel, J. Long +2 more
2018Clinical studies10 citations
Semantic Scholar
Translational Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling Strategy to Support RG6042 Dose Selection in Huntington’s Disease (HD) (S16.005)
P. Ducray, Nic Frances, Kevin Smart, Dan Norris +4 more
2019Neurology9 citations
Semantic Scholar
Huntington's Disease Integrated Staging System (HD-ISS): A Novel Evidence-Based Classification System For Staging
S. Tabrizi, S. Schobel, E. Gantman, A. Mansbach +13 more
2021medRxiv7 citations Open access
Semantic Scholar
Longitudinal dynamics of mutant huntingtin and neurofilament light in Huntington's disease: the prospective HD-CSF study
F. Rodrigues, L. Byrne, R. Tortelli, E. Johnson +13 more
2020medRxiv7 citations Open access
Semantic Scholar
J01 Effects of IONIS-HTTRX (RG6042) in patients with early huntington’s disease, results of the first htt-lowering drug trial
S. Tabrizi, Blair R. Leavitt, Bernhard Landwehrmeyer, Edward J. Wild +16 more
2018Clinical Therapeutics7 citations
Semantic Scholar
The Digital-HD study: Smartphone-Based Remote Testing to Assess Cognitive and Motor Symptoms in Huntington’s Disease (1816)
R. Tortelli, C. Simillion, F. Lipsmeier, T. Kilchenmann +7 more
2020Neurology4 citations
Semantic Scholar
Abstracts from HSG 2019
Beltran-Najera, Lisa V. Graves, H. Holden, M. Savanna +25 more
2019Neurotherapeutics4 citations Open access
Semantic Scholar
F61 Digital, high-frequency, long-term monitoring of motor and non-motor symptoms in huntington’s disease (hd) patients
F. Lipsmeier, Wei-Yi Cheng, D. Wolf, Yan-Ping Zhang +8 more
2018Clinical studies4 citations
Semantic Scholar
F14 Collaborating with the community to conduct clinical trials in huntington’s disease: lessons from the tominersen phase iii generation HD1 study
Victoria Liddy, D. West, Maileah Nguyen, L. Boak +4 more
2021F: Clinical studies: case reports, oberservational studies and trials2 citations
Semantic Scholar
Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease (S16.003)
Filipe B. Rodrigues, L. Byrne, E. Johnson, Peter Wijeratne +9 more
2019Neurology2 citations
Semantic Scholar
A safety, tolerability and biomarker update from an ongoing open-label extension study of RG6042 in adults with early manifest Huntington’s disease
B. Leavitt, Sarah J. Tabrizi, P. Ducray, Edward J. Wild +10 more
2019Journal of Neurological Sciences2 citations
Semantic Scholar
Using Functional Status to Aid Interpretation of Composite Unified Huntington’s Disease Rating Scale (cUHDRS) Scores in Patients with Huntington’s Disease (HD) (951)
D. Trundell, Giuseppe Palermo, Jeffery D. Long, B. Leavitt +2 more
2020Neurology1 citations
Semantic Scholar
Discovering Dominant Features Associated with Disease Progression in Huntington’s Disease (HD): A Data-driven Approach Using the Enroll-HD Database (1603)
Naghmeh Ghazaleh, R. Houghton, Giuseppe Palermo, S. Schobel +2 more
2020Neurology1 citations
Semantic Scholar
Preliminary Reliability and Validity of a Novel Digital Biomarker Smartphone Application to Assess Cognitive and Motor Symptoms in Huntington’s Disease (HD) (P1.8-042)
F. Lipsmeier, C. Simillion, A. Bamdadian, Anne Smith +6 more
2019Neurology1 citations
Semantic Scholar
Using functional status to aid interpretation of the composite unified huntington’s disease rating scale (cUHDRS) scores in patients with huntington’s disease (HD)
Dylan Trundell, Giuseppe Palermo, Jeffrey D. Long, B. Leavitt +2 more
2019Journal of Neurological Sciences1 citations
Semantic Scholar
Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a pathogenic driver
S. Schobel, Nashid H. Chaudhury, Usman A. Khan, B. Paniagua +8 more
20141 citations
Semantic Scholar

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