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Matthew C. Sinton · SciRah

Researcher profile · Semantic Scholar

Matthew C. Sinton

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Matthew C. Sinton — researcher profile on SciRah

h-index: 11
Works: 38
Citations: 550

Most-cited papers

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis
K. Suchacki, A. Tavares, Domenico Mattiucci, E. Scheller +24 more
2020Nature Communications180 citations Open access
Semantic Scholar
The Influence of Sex Hormones in Liver Function and Disease
Alvile Kasarinaite, Matthew C. Sinton, P. Saunders, David C. Hay
2023Cells111 citations Open access
Semantic Scholar
Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection
Juan F. Quintana, Praveena R. G. Chandrasegaran, Matthew C. Sinton, E. Briggs +7 more
2022Nature Communications39 citations Open access
Semantic Scholar
Metabolic control of gene transcription in non-alcoholic fatty liver disease: the role of the epigenome
Matthew C. Sinton, David C. Hay, A. Drake
2019Clinical Epigenetics37 citations Open access
Semantic Scholar
Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease
Abigail C. Lay, Van Du T. Tran, V. Nair, Virginie M. Betin +21 more
2024Nature Communications30 citations Open access
Semantic Scholar
A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis
Matthew C. Sinton, Jose Meseguer-Ripolles, B. Lucendo-Villarin, S. Wernig-Zorc +12 more
2020iScience29 citations Open access
Semantic Scholar
From fat storage to immune hubs: the emerging role of adipocytes in coordinating the immune response to infection
Matthew C. Sinton, S. Kajimura
2024The FEBS Journal17 citations Open access
Semantic Scholar
γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
Juan F. Quintana, Matthew C. Sinton, Praveena R. G. Chandrasegaran, Agatha Nabilla Lestari +9 more
2023Nature Communications17 citations Open access
Semantic Scholar
IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection
Matthew C. Sinton, Praveena R. G. Chandrasegaran, P. Capewell, Anneli Cooper +12 more
2023Nature Communications17 citations Open access
Semantic Scholar
Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress
E. Fitzgerald, Matthew C. Sinton, S. Wernig-Zorc, N. Morton +3 more
2021Epigenetics & Chromatin14 citations Open access
Semantic Scholar
The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection
Juan F. Quintana, Matthew C. Sinton, Praveena R. G. Chandrasegaran, Lalit Kumar Dubey +10 more
2023bioRxiv13 citations Open access
Semantic Scholar
Increasing the visibility of LGBTQ+ researchers in STEM.
Matthew C. Sinton, K. Baines, Kiri A Thornalley, Vinodh Ilangovan +1 more
2020The Lancet10 citations Open access
Semantic Scholar
Modelling host- Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids
Praveena R. G. Chandrasegaran, Agatha Nabilla Lestari, Matthew C. Sinton, J. Gopalakrishnan +1 more
2023F1000Research6 citations Open access
Semantic Scholar
Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes
Matthew C. Sinton, Jose Meseguer-Ripolles, B. Lucendo-Villarin, A. Drake +1 more
2021STAR Protocols6 citations Open access
Semantic Scholar
Interleukin-17 drives sex-dependent weight loss and changes in feeding behaviour 1 during Trypanosoma brucei infection
Matthew C. Sinton, A. Girard, John Ogunsola, Praveena R. G. Chandrasegaran +16 more
20225 citations
Semantic Scholar
Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia-plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection
Juan F. Quintana, Praveena R. G. Chandrasegaran, Matthew C. Sinton, E. Briggs +7 more
2022bioRxiv4 citations Open access
Semantic Scholar
Perspectives of a gay scientist: the importance of being visible
Matthew C. Sinton
2022Immunology and Cell Biology4 citations Open access
Semantic Scholar
Altered hypothalamic DNA methylation and stress-induced hyperactivity in a novel model of early life stress
E. Fitzgerald, Matthew C. Sinton, S. Wernig-Zorc, N. Morton +3 more
2020bioRxiv3 citations Open access
Semantic Scholar
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in systemic glucose homeostasis
K. Suchacki, A. Tavares, Domenico Mattiucci, E. Scheller +24 more
2019bioRxiv3 citations Open access
Semantic Scholar
Interleukin-17 and fat: Timing is everything.
Matthew C. Sinton, Olivia Shorthouse, A. Costain, Juan F. Quintana
2025Immunity2 citations Open access
Semantic Scholar
IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection
Matthew C. Sinton, Praveena R. G. Chandrasegaran, P. Capewell, Anneli Cooper +11 more
2023bioRxiv2 citations Open access
Semantic Scholar
Nonalcoholic fatty liver disease is associated with decreased hepatocyte mitochondrial respiration, but not mitochondrial number
Matthew C. Sinton, J. Ripolles, B. L. Villarin, M. Lyall +4 more
2020bioRxiv2 citations Open access
Semantic Scholar
Spatial Transcriptomics Reveals Region-Specific Host Responses in Amoebic Gill Disease of Atlantic Salmon
Yee-Wan Liu, Bachar Cheaib, A. Bacigalupo, Brendan A. Robertson +14 more
2026bioRxiv0 citations Open access
Semantic Scholar
Dual faces of γδ T cells in trypanosomatid infections.
P. P. D. Lucinda, Matthew C. Sinton, Juan F. Quintana, W. Dutra
2026Trends in Parasitology0 citations Open access
Semantic Scholar
Publisher Correction: IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection
Matthew C. Sinton, Praveena R. G. Chandrasegaran, P. Capewell, Anneli Cooper +12 more
2024Nature Communications0 citations Open access
Semantic Scholar
FISHtoFigure: An easy-to-use tool for rapid, multi-target partitioning and analysis of sub-cellular mRNA transcripts in smFISH data
Calum Bentley-Abbot, Rhiannon Heslop, Chiara Pirillo, Matthew C. Sinton +5 more
2023bioRxiv0 citations Open access
Semantic Scholar
Spatially-resolved single cell transcriptomics reveal a critical role for γδ T cells in the control of skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection
Juan F. Quintana, Matthew C. Sinton, Praveena R. G. Chandrasegaran, Agatha Nabilla Lestari +8 more
2023bioRxiv0 citations Open access
Semantic Scholar
The murine meninges acquire lymphoid tissue properties and harbour 1 autoreactive B cells during chronic Trypanosoma brucei infection 2
Juan F. Quintana, Matthew C. Sinton, Praveena R. G. Chandrasegaran, Lalit Kumar +10 more
20230 citations
Semantic Scholar
Single cell and spatial transcriptomic analyses reveal microglia-plasma cell 1 crosstalk in the brain during Trypanosoma brucei infection 2
Juan F. Quintana, Praveena R. G. Chandrasegaran, Matthew C. Sinton, E. Briggs +8 more
20220 citations
Semantic Scholar
Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress
E. Fitzgerald, Matthew C. Sinton, S. Wernig-Zorc, N. Morton +3 more
2021Epigenetics & Chromatin0 citations Open access
Semantic Scholar
Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of 1 purine nucleotide cycle driven fumarate accumulation
Matthew C. Sinton, B. L. Villarin, J. Ripolles, Sara Wernig +7 more
20200 citations
Semantic Scholar
Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of purine nucleotide cycle driven fumarate accumulation
Matthew C. Sinton, Baltasar Lucendo Villarin, Jose Meseguer Ripolles, S. Wernig-Zorc +8 more
2020bioRxiv0 citations Open access
Semantic Scholar
Transcriptomic analysis revealed perturbation of mitochondrial respiratory pathways in LPO
Matthew C. Sinton, B. L. Villarin, J. Ripolles, Sara Wernig +7 more
20200 citations
Semantic Scholar
Linking mitochondrial metabolism and macrovesicular steatosis in non-alcoholic fatty liver disease
Matthew C. Sinton
20200 citations
Semantic Scholar
GC-MS analysis of steatotic hepatocyte-like cells
Matthew C. Sinton, M. Drake, D. Tennant
20200 citations
Semantic Scholar
Single Cell Analysis Reveals Immune Cell-Adipocyte Crosstalk Regulating the Transcription of Thermogenic Adipocytes
Matthew C. Sinton
20190 citations
Semantic Scholar
[18F]-FDG PET/CT imaging: A tool to reveal the metabolic functions of bone marrow adipose tissue
K. Suchacki, A. Tavares, Matthew C. Sinton, Carlos Alcaide +2 more
20180 citations
Semantic Scholar
Oral presentations Bi-directional signalling between the intestinal epithelium and type-3 innate lymphoid cells (ILC3) via the Notch pathway
T. Brabec, Dobešová, Ben-Nun, Dobeš +32 more
0 citations
Semantic Scholar

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Juan F. Quintana×16
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Praveena R. G. Chandrasegaran×14
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Praveena R. G. Chandrasegaran — researcher profile on SciRah
A. Drake×10
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John Ogunsola×9
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David C. Hay×5

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