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D. Nikolopoulos · SciRah

Researcher profile · Semantic Scholar

D. Nikolopoulos

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D. Nikolopoulos — researcher profile on SciRah

h-index: 21
Works: 104
Citations: 1,290

Most-cited papers

Microglia activation in the presence of intact blood–brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus
D. Nikolopoulos, T. Manolakou, A. Polissidis, A. Filia +3 more
2023Annals of the Rheumatic Diseases115 citations Open access
Semantic Scholar
Lupus or not? SLE Risk Probability Index (SLERPI): a simple, clinician-friendly machine learning-based model to assist the diagnosis of systemic lupus erythematosus
C. Adamichou, I. Genitsaridi, D. Nikolopoulos, M. Nikoloudaki +6 more
2021Annals of the Rheumatic Diseases103 citations Open access
Semantic Scholar
Cardiovascular Disease in Systemic Lupus Erythematosus: recent data on epidemiology, risk factors and prevention.
M. Kostopoulou, D. Nikolopoulos, I. Parodis, G. Bertsias
2019Current Vascular Pharmacology95 citations
Semantic Scholar
In an early SLE cohort the ACR-1997, SLICC-2012 and EULAR/ACR-2019 criteria classify non-overlapping groups of patients: use of all three criteria ensures optimal capture for clinical studies while their modification earlier classification and treatment
C. Adamichou, D. Nikolopoulos, I. Genitsaridi, A. Bortoluzzi +7 more
2019Annals of the Rheumatic Diseases93 citations
Semantic Scholar
Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus
M. Grigoriou, A. Banos, A. Filia, P. Pavlidis +8 more
2019Annals of the Rheumatic Diseases81 citations Open access
Semantic Scholar
Cerebrovascular Events in Systemic Lupus Erythematosus: Diagnosis and Management
D. Nikolopoulos, A. Fanouriakis, D. Boumpas
2019Mediterranean Journal of Rheumatology72 citations Open access
Semantic Scholar
Evolving phenotype of systemic lupus erythematosus in Caucasians: low incidence of lupus nephritis, high burden of neuropsychiatric disease and increased rates of late-onset lupus in the ‘Attikon’ cohort
D. Nikolopoulos, M. Kostopoulou, A. Pieta, T. Karageorgas +10 more
2020Lupus50 citations Open access
Semantic Scholar
ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus
T. Manolakou, D. Nikolopoulos, D. Gkikas, A. Filia +8 more
2022Science Advances38 citations Open access
Semantic Scholar
Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis
E. Frangou, P. Garantziotis, M. Grigoriou, A. Banos +13 more
2022Annals of the Rheumatic Diseases32 citations Open access
Semantic Scholar
Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis
I. Parodis, J. Lindblom, D. Toro-Domínguez, L. Beretta +8 more
2024Kidney International Reports31 citations Open access
Semantic Scholar
Janus kinase inhibitors in systemic lupus erythematosus: implications for tyrosine kinase 2 inhibition
D. Nikolopoulos, I. Parodis
2023Frontiers in Medicine29 citations Open access
Semantic Scholar
Reframing health disparities in SLE: A critical reassessment of racial and ethnic differences in lupus disease outcomes.
I. Parodis, C. Lanata, D. Nikolopoulos, Ashira D. Blazer +1 more
2023Baillière's Best Practice & Research : Clinical Rheumatology28 citations Open access
Semantic Scholar
Clinical response trajectories and drug persistence in systemic lupus erythematosus patients on belimumab treatment: A real-life, multicentre observational study
M. Nikoloudaki, D. Nikolopoulos, S. Koutsoviti, I. Flouri +12 more
2023Frontiers in Immunology28 citations Open access
Semantic Scholar
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events
D. Nikolopoulos, C. Loukogiannaki, G. Sentis, P. Garantziotis +10 more
2024Annals of the Rheumatic Diseases27 citations Open access
Semantic Scholar
Transition to severe phenotype in systemic lupus erythematosus initially presenting with non-severe disease: implications for the management of early disease
D. Nikolopoulos, M. Kostopoulou, A. Pieta, S. Flouda +6 more
2020Lupus Science and Medicine27 citations Open access
Semantic Scholar
Update on the pathogenesis of central nervous system lupus.
D. Nikolopoulos, A. Fanouriakis, D. Boumpas
2019Current Opinion in Rheumatology26 citations
Semantic Scholar
Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways
G. Moysidou, P. Garantziotis, G. Sentis, D. Nikoleri +13 more
2024Annals of the Rheumatic Diseases25 citations Open access
Semantic Scholar
Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus.
P. Garantziotis, L. Beretta, J. Lindblom, G. Moysidou +14 more
2025Annals of the Rheumatic Diseases24 citations Open access
Semantic Scholar
Demyelinating Syndromes in Systemic Lupus Erythematosus: Data From the “Attikon” Lupus Cohort
D. Nikolopoulos, D. Kitsos, M. Papathanasiou, N. Kapsala +7 more
2022Frontiers in Neurology22 citations Open access
Semantic Scholar
Treatment of neuropsychiatric systemic lupus erythematosus: clinical challenges and future perspectives
D. Nikolopoulos, A. Fanouriakis, G. Bertsias
2021Expert Review of Clinical Immunology21 citations
Semantic Scholar
From first symptoms to diagnosis of systemic lupus erythematosus: mapping the journey of patients in an observational study.
N. Kapsala, D. Nikolopoulos, S. Flouda, Aikaterini P Chavatza +6 more
2021Clinical and Experimental Rheumatology21 citations
Semantic Scholar
Remission or low disease activity at pregnancy onset are linked to improved foetal outcomes in women with systemic lupus erythematosus: results from a prospective observational study.
Styliani Ntali, D. Nikolopoulos, L. Pantazi, E. Emmanouilidou +9 more
2021Clinical and Experimental Rheumatology19 citations
Semantic Scholar
First diagnosis of systemic lupus erythematosus in hospitalized patients: Clinical phenotypes and pitfalls for the non-specialist.
N. Kapsala, D. Nikolopoulos, S. Flouda, Aikaterini P Chavatza +6 more
2021American Journal of Medicine18 citations
Semantic Scholar
Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study.
Ş. Yavuz, D. Cansu, D. Nikolopoulos, F. Crisafulli +18 more
2020Seminars in Arthritis & Rheumatism18 citations
Semantic Scholar
Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients
K. Chavatza, M. Kostopoulou, D. Nikolopoulos, O. Gioti +13 more
2021Annals of the Rheumatic Diseases15 citations Open access
Semantic Scholar
Patients with NPSLE experience poorer HRQoL and more fatigue than SLE patients with no neuropsychiatric involvement, irrespective of neuropsychiatric activity
D. Nikolopoulos, N. Cetrez, J. Lindblom, L. Palazzo +2 more
2024Rheumatology14 citations Open access
Semantic Scholar
A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
G. Sentis, C. Loukogiannaki, Nikos Malissovas, D. Nikolopoulos +6 more
2023Frontiers in Immunology13 citations Open access
Semantic Scholar
THU0245 PENALIZED REGRESSION ANALYSIS IDENTIFIES CRITERIA AND NON-CRITERIA FEATURES THAT MAY INCREASE THE ACCURACY OF EXISTING SETS OF CRITERIA FOR CLASSIFYING SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
C. Adamichou, I. Genitsaridi, D. Nikolopoulos, Alessandra Bortoluzzi +7 more
2020Annals of the Rheumatic Diseases12 citations Open access
Semantic Scholar
Suspected systemic rheumatic diseases in patients presenting with cytopenias.
D. Nikolopoulos, C. Adamichou, G. Bertsias
2019Baillière's Best Practice & Research : Clinical Rheumatology12 citations
Semantic Scholar
Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy
D. Nikolakis, P. Garantziotis, G. Sentis, A. Fanouriakis +5 more
2023BMC Genomics11 citations Open access
Semantic Scholar
The role of plasma exchange in antineutrophil cytoplasmic antibody-associated vasculitis: a meta-analysis
I. Bellos, Ioannis Michelakis, D. Nikolopoulos
2020Clinical Rheumatology11 citations
Semantic Scholar
Enhanced B cell and complement cascade gene signatures in patients with neuropsychiatric systemic lupus erythematosus.
D. Nikolopoulos, G. Sentis, Iasonas Kitsios, P. Garantziotis +12 more
2025Annals of the Rheumatic Diseases10 citations Open access
Semantic Scholar
New IgG and IgA autoantibody specificities against DNA-binding and RNA-binding proteins discriminate systemic lupus erythematosus from health and non-lupus autoimmunity-could anti-LIN28A enhance precision in diagnostics?
I. Parodis, Denis Lagutkin, J. Lindblom, H. Idborg +8 more
2025Annals of the Rheumatic Diseases10 citations Open access
Semantic Scholar
Tailored treatment strategies and future directions in systemic lupus erythematosus
D. Nikolopoulos, Lampros Fotis, O. Gioti, A. Fanouriakis
2022Rheumatology International10 citations
Semantic Scholar
Belimumab efficacy in mucocutaneous manifestations of systemic lupus erythematosus: a large post hoc analysis of five phase III clinical trials
G. Grosso, N. Giannopoulou, Alexander Tsoi, N. Cetrez +3 more
2025Rheumatology9 citations Open access
Semantic Scholar
Neuropsychiatric involvement in systemic lupus erythematosus contributes to organ damage beyond the nervous system: a post-hoc analysis of 5 phase III randomized clinical trials
D. Nikolopoulos, N. Cetrez, J. Lindblom, I. Parodis
2024Rheumatology International9 citations Open access
Semantic Scholar
Demyelination with autoimmune features (DAF): A distinct clinical entity? Results from a longitudinal cohort.
D. Nikolopoulos, D. Kitsos, M. Papathanasiou, M. Chondrogianni +8 more
2021Rheumatology9 citations
Semantic Scholar
Unsupervised machine learning identifies distinct SLE patient endotypes with differential response to belimumab
R. Depascale, Raffaele Da Mutten, J. Lindblom, N. Cetrez +6 more
2025Rheumatology8 citations
Semantic Scholar
Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1.
J. Lindblom, Denis Lagutkin, N. Sherina, H. Idborg +8 more
2025Annals of the Rheumatic Diseases8 citations Open access
Semantic Scholar
Can we predict kidney involvement in patients with systemic lupus erythematosus? A retrospective cohort study with independent validation.
S. Katechis, D. Nikolopoulos, S. Flouda, C. Adamichou +6 more
2024Rheumatology8 citations
Semantic Scholar
Evolving Concepts in Treat-to-Target Strategies for Systemic Lupus Erythematosus
D. Nikolopoulos, M. H. Lourenço, R. Depascale, K. Triantafyllias +1 more
2024Mediterranean Journal of Rheumatology8 citations Open access
Semantic Scholar
Trajectories of disease evolution upon treatment initiation in systemic lupus erythematosus: results from four clinical trials of belimumab
I. Parodis, J. Lindblom, Alexander Tsoi, L. Palazzo +4 more
2024Rheumatology7 citations Open access
Semantic Scholar
Advances in the pharmacological management of systemic lupus erythematosus
Alexander Tsoi, D. Nikolopoulos, I. Parodis
2024Expert Opinion on Pharmacotherapy7 citations Open access
Semantic Scholar
Relapses are common in severe hematologic systemic lupus erythematosus and may be prevented by early institution of immunosuppressive agents: Α real-life single-center study
G. Moysidou, P. Garantziotis, D. Nikolopoulos, P. Katsimbri +2 more
2022Lupus7 citations
Semantic Scholar
Transcriptome analysis to decipher the molecular underpinnings of response to treatment in systemic lupus erythematosus
P. Garantziotis, G. Moysidou, N. Kapsala, S. Flouda +11 more
2025RMD Open6 citations Open access
Semantic Scholar
Dysregulation of innate and adaptive lymphoid immunity may have implications for symptom attribution and predict responses to targeted therapies in neuropsychiatric systemic lupus erythematosus
J. Lindblom, G. Barturen, L. Beretta, D. Toro-Domínguez +56 more
2025Journal of Translational Autoimmunity6 citations Open access
Semantic Scholar
Systemic lupus erythematosus damage risk index (SLE-DRI): a simple machine learning-based tool for identifying patients at risk for early organ damage
P. Garantziotis, D. Nikolopoulos, S. Katechis, Alp Temiz +8 more
2025RMD Open6 citations Open access
Semantic Scholar
The Multiple Faces of Systemic Lupus Erythematosus: Pearls and Pitfalls for Diagnosis
N. Kapsala, D. Nikolopoulos, A. Fanouriakis
2024Mediterranean Journal of Rheumatology6 citations Open access
Semantic Scholar
Glycomic Profiles of IgG, C3 and Alpha-1-Acid Glycoprotein (AGP) Before and One Year After Treatment for Active Lupus Nephritis
D. Nikolopoulos, A. Cindrić, Konstantinos Charitidis, N. Sherina +9 more
2026Cells3 citations Open access
Semantic Scholar
Old and new autoantibodies in systemic lupus erythematosus
I. Parodis, D. Nikolopoulos, André Brylid, O. Hultgren +2 more
2026Expert Review of Clinical Immunology3 citations Open access
Semantic Scholar

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