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Chia-Wei Chang · SciRah

Researcher profile · Semantic Scholar

Chia-Wei Chang

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Chia-Wei Chang — researcher profile on SciRah

h-index: 17
Works: 46
Citations: 1,998

Most-cited papers

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation
Ichiro Hiratani, T. Ryba, M. Itoh, T. Yokochi +6 more
2008PLoS Biology561 citations Open access
Semantic Scholar
Polycistronic Lentiviral Vector for “Hit and Run” Reprogramming of Adult Skin Fibroblasts to Induced Pluripotent Stem Cells
Chia-Wei Chang, Yi-Shin Lai, Kevin M. Pawlik, Kai-Mao Liu +4 more
2009Stem Cells227 citations
Semantic Scholar
MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer
Chun-Wen Cheng, Hsiao-Wei Wang, Chia-Wei Chang, Hou-Wei Chu +6 more
2012Breast Cancer Research and Treatment208 citations
Semantic Scholar
PRC2 Complexes with JARID2, MTF2, and esPRC2p48 in ES Cells to Modulate ES Cell Pluripotency and Somatic Cell Reprograming
Zhuo Zhang, Amanda E. Jones, Chiao-Wang Sun, Chao Li +15 more
2011Stem Cells166 citations Open access
Semantic Scholar
Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting
Chia-Wei Chang, Yi-Shin Lai, Erik R. Westin, A. Khodadadi-Jamayran +4 more
2015Cell Reports104 citations Open access
Semantic Scholar
Solasodine inhibits invasion of human lung cancer cell through downregulation of miR-21 and MMPs expression.
Kun-Hung Shen, Jui-Hsiang Hung, Chia-Wei Chang, Yu-Ting Weng +2 more
2017Chemico-Biological Interactions88 citations
Semantic Scholar
The clinical implications of MMP-11 and CK-20 expression in human breast cancer.
Chun-Wen Cheng, Jyh-Cherng Yu, Hsiao-Wei Wang, Chiun-Sheng Huang +5 more
2010Clinica chimica acta; international journal of clinical chemistry63 citations
Semantic Scholar
MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition and metastasis by targeting Slug in breast cancer
Chia-Wei Chang, Jyh-Cherng Yu, Yi-Hsien Hsieh, Chung-Chin Yao +7 more
2016OncoTarget61 citations Open access
Semantic Scholar
SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency
Yi-Shin Lai, Chia-Wei Chang, Kevin M. Pawlik, De-Wang Zhou +2 more
2012Proceedings of the National Academy of Sciences of the United States of America58 citations Open access
Semantic Scholar
Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in erk-responsive lung cancer
Chun-Wen Cheng, Po-Ming Chen, Yi-Hsien Hsieh, Chung-Chih Weng +5 more
2015OncoTarget57 citations Open access
Semantic Scholar
The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells.
Zhenhua Yang, Jonathan J Augustin, Chen-Bei Chang, Jing Hu +4 more
2014Blood55 citations Open access
Semantic Scholar
Regulatory mechanisms of B cell responses and the implication in B cell-related diseases
Dong-Yan Tsai, Kuo-Hsuan Hung, Chia-Wei Chang, Kuo-I Lin
2019Journal of Biomedical Sciences54 citations Open access
Semantic Scholar
Distinct classes of c-Kit-activating mutations differ in their ability to promote RUNX1-ETO-associated acute myeloid leukemia.
H. J. Nick, Hyung-Gyoong Kim, Chia-Wei Chang, K. Harris +2 more
2012Blood41 citations Open access
Semantic Scholar
Broad T-Cell Receptor Repertoire in T-Lymphocytes Derived from Human Induced Pluripotent Stem Cells
Chia-Wei Chang, Yi-Shin Lai, L. Lamb, T. Townes
2014PLoS ONE33 citations Open access
Semantic Scholar
The Universal 3D3 Antibody of Human PODXL Is Pluripotent Cytotoxic, and Identifies a Residual Population After Extended Differentiation of Pluripotent Stem Cells
Lei Kang, Chunping Yao, A. Khodadadi-Jamayran, Wei-Hua Xu +6 more
2016Stem Cells and Development31 citations Open access
Semantic Scholar
A Chimeric Antigen Receptor Uniquely Recognizing MICA/B Stress Proteins Provides an Effective Approach to Target Solid Tumors
J. Goulding, Wen-I Yeh, Bryan M. Hancock, R. Blum +23 more
2023i Medicina26 citations Open access
Semantic Scholar
FT819: Translation of Off-the-Shelf TCR-Less Trac-1XX CAR-T Cells in Support of First-of-Kind Phase I Clinical Trial
Chia-Wei Chang, S. V. D. van der Stegen, Mandal Mili, Raedun Clarke +17 more
2019Blood24 citations Open access
Semantic Scholar
Bisphenol A-induced DNA damages promote to lymphoma progression in human lymphoblastoid cells through aberrant CTNNB1 signaling pathway
Yin-Kai Chen, Yanfang Tan, M. Yao, Ho-Chen Lin +7 more
2021iScience17 citations Open access
Semantic Scholar
Marginal Zone B Cells Assist With Neutrophil Accumulation to Fight Against Systemic Staphylococcus aureus Infection
L. Lo, Chia-Wei Chang, Ming-Feng Chiang, I-Ying Lin +1 more
2021Frontiers in Immunology17 citations Open access
Semantic Scholar
Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells
Zhong Liu, Cheng Zhang, Maria Skamagki, A. Khodadadi-Jamayran +9 more
2017Stem Cell Reports14 citations Open access
Semantic Scholar
The Causal Relationship of Circulating Triglycerides and Glycated Hemoglobin: A Mendelian Randomization Study.
Chia-Ni Hsiung, Yi-Cheng Chang, Chien-Wei Lin, Chia-Wei Chang +5 more
2019Journal of Clinical Endocrinology and Metabolism12 citations Open access
Semantic Scholar
Clinical Manufacture of FT819: Use of a Clonal Multiplexed-Engineered Master Induced Pluripotent Stem Cell Line to Mass Produce Off-the-Shelf CAR T-Cell Therapy
Xu Yuan, Raedun Clarke, Yi-Shin Lai, Chia-Wei Chang +22 more
2021Blood10 citations Open access
Semantic Scholar
Pluripotent Cell-Derived Off-the-Shelf TCR-Less CAR-Targeted Cytotoxic T Cell Therapeutic for the Allogeneic Treatment of B Cell Malignancies
Raedun Clarke, S. V. D. van der Stegen, Chia-Wei Chang, Mushtaq Husain +17 more
2018Blood10 citations Open access
Semantic Scholar
iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors
Bi-Huei Yang, Alma Gutierrez, A. Liao, S. Shirinbak +13 more
2025Cell Reports Medicine9 citations Open access
Semantic Scholar
Dual Chimeric Antigen Receptor Approach Combining Novel Tumor Targeting Strategies Circumvents Antigen Escape in Multiple Myeloma
John Reiser, K. Mathavan, Sajid Mahmood, Yijia Pan +13 more
2021Blood9 citations Open access
Semantic Scholar
Abstract 3245: FT819 path to IND: First-of-kind off-the-shelf CAR19 T-cell for B cell malignancies
M. Mandal, Raedun Clarke, S. V. D. van der Stegen, Chia-Wei Chang +22 more
2020Immunology8 citations
Semantic Scholar
Abstract LB-108: Generation of off-the-shelf TCR-less CAR-targeted cytotoxic T cells from renewable pluripotent cells for cancer immunotherapy
Raedun Clarke, S. V. D. van der Stegen, Tom Lee, J. Mansilla-Soto +9 more
2018Immunology7 citations
Semantic Scholar
Abstract 1591: FT536: Preclinical development of a novel off-the-shelf CAR-MICA/B NK cell immunotherapy combined with radiation and antibody treatments as a first-of-kind pan-cancer targeting strategy
J. Goulding, R. Blum, Bryan M. Hancock, M. Ge +20 more
2021Immunology6 citations
Semantic Scholar
OL-101, a BCMA/GPRC5D dual-targeting autologous CAR-T for relapsed/ refractory multiple myeloma (R/R MM): Results from a Phase I study
Yong-Xian Hu, Ming-Ming Zhang, Ya-Jing Zhang, Shan Fu +7 more
2025Blood3 citations
Semantic Scholar
204 Combining FT536, a pan-tumor targeting CAR NK cell therapy, with CD16 engagers provides a coordinated targeting strategy to overcome tumor heterogeneity
J. Goulding, Bryan M. Hancock, R. Blum, Wen-I Yeh +17 more
2022Regular and Young Investigator Award Abstracts3 citations Open access
Semantic Scholar
Azithromycin Plus Zinc Sulfate Rapidly and Synergistically Suppresses IκBα-Mediated In Vitro Human Airway Cell ACE2 Expression for SARS-CoV-2 Entry
Chia-Wei Chang, Ming-Cheng Lee, Bor-Ru Lin, Yen-Pei Lu +4 more
2021bioRxiv3 citations Open access
Semantic Scholar
Development of a Novel MICA/B-Specific CAR As a Pan-Tumor Targeting Strategy for Off-the-Shelf, Cell-Based Cancer Immunotherapy
R. Bjordahl, J. Goulding, Mochtar Pribadi, R. Blum +14 more
20203 citations Open access
Semantic Scholar
Generation of Multiplexed Engineered, Off-the-Shelf CAR T Cells Uniformly Carrying Multiple Anti-Tumor Modalities to Prevent Tumor Relapse
Chia-Wei Chang, Eigen Peralta, Gloria Hsia, Bi-Huei Yang +26 more
20202 citations Open access
Semantic Scholar
326 Off-the-shelf iPSC-derived CAR-T cells targeting KLK2 demonstrate prolonged tumor control and survival in xenograft models of prostate cancer
Charles Drake, Alex Garcia, Chia-Wei Chang, Bi-Huei Yang +14 more
2022Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
Abstract 4190: Combining dual CAR iPSC-derived immune cells with antibody for multi-antigen targeting to overcome clonal resistance in multiple myeloma
K. Mathavan, John Reiser, Sajid Mahmood, Yi-Chung Pan +13 more
2022Cancer Research1 citations
Semantic Scholar
Multiplexed Engineered, Off-the-Shelf T Cells Carrying Three Tumor-Associated Antigen-Targeting Modalities: CAR + Pan-Tumor Targeting TCR + CD16 Fc Receptor
Cokey Nguyen, Eigen Peralta, Chia-Wei Chang, Wen-I Yeh +8 more
20201 citations
Semantic Scholar
Abstract 2216: Combinational strategy targeting B cell malignancy using iPSC engineered CAR-NK (FT596) and CAR-T cell (FT819) platforms with therapeutic antibody to achieve an effective deep and durable response
Jode Goodridge, John Reiser, R. Bjordahl, M. Mandal +16 more
2020Immunology1 citations
Semantic Scholar
Generation of Clonal Antigen Specific CD8αβ+ Cytotoxic T Lymphocytes from Renewable Pluripotent Stem Cells for Off-the-Shelf T Cell Therapeutics
S. V. D. van der Stegen, Raedun Clarke, Jorge Mansilla Soto, Edwin Ortiz +8 more
20171 citations
Semantic Scholar
Polycistronic lentiviral vector for hit and run reprogramming of mouse and human somatic cells to induced pluripotent stem cell
Chia-Wei Chang
20091 citations
Semantic Scholar
246 A GPRC5D and BCMA bispecific CAR-T product demonstrated dual antigen targeting capability and efficacy against multiple myeloma cells bearing BCMA mutations associated with treatment resistance
Chia-Wei Chang, Yong-Hua Luo, A. S. Pal, H. Ding +4 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
300 Tri-modal CAR+TCR+hnCD16+iPSC-derived T cells co-targeting surface and intracellular/neoantigens demonstrate additive effect on overcoming tumor heterogeneity and cancer escape
Bi-Huei Yang, S. Shirinbak, Wen-I Yeh, Alma Gutierrez +11 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
114 Preclinical development of a novel iPSC-derived CAR-MICA/B NK cell immunotherapy to overcome solid tumor escape from NKG2D-mediated mechanisms of recognition and killing
J. Goulding, Mochtar Pribadi, R. Blum, Wen-I Yeh +13 more
20200 citations Open access
Semantic Scholar
Construction of an E . coli-Leishmania shuttle vector
Chia-Wei Chang, Chien-Yu Hsu, J. Hsu, Yu-Chang Ku +11 more
20170 citations
Semantic Scholar
Modified IPS Cells for Hemoglobinopathies
T. Townes, Lei Ding, Chia-Wei Chang, Yi-Shin Lai +2 more
20150 citations
Semantic Scholar
Role Of Dpy30/MLL Complexes In Regulating Hematopoietic Progenitor Cell Maintenance and Differentiation
Zhenhua Yang, Jonathan J Augustin, Jing Hu, Chia-Wei Chang +2 more
20130 citations
Semantic Scholar
Abstract 1094: MicroRNA-30a inhibits vimentin expression and as a prognostic marker in breast cancer
Chia-Wei Chang, Chun-Wen Cheng, Hsiao-Wei Wang, Cheng Chen +5 more
20120 citations
Semantic Scholar

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