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Melanie G. Kirkpatrick · SciRah

Researcher profile · Semantic Scholar

Melanie G. Kirkpatrick

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Melanie G. Kirkpatrick — researcher profile on SciRah

h-index: 11
Works: 25
Citations: 773

Most-cited papers

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
B. Boras, Rhys M. Jones, B. Anson, D. Arenson +48 more
2021Nature Communications231 citations Open access
Semantic Scholar
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
M. Bakowski, N. Beutler, Karen C. Wolff, Melanie G. Kirkpatrick +28 more
2021Nature Communications109 citations Open access
Semantic Scholar
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
G. Garcia, Arun Sharma, A. Ramaiah, C. Sen +24 more
2021Cell Reports101 citations Open access
Semantic Scholar
Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19
B. Boras, Rhys M. Jones, B. Anson, D. Arenson +45 more
2020bioRxiv96 citations Open access
Semantic Scholar
Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection.
Allison N. Bucşan, Ayan Chatterjee, D. Singh, Taylor W. Foreman +11 more
2019Journal of Clinical Investigation67 citations Open access
Semantic Scholar
1997 Index of Economic Freedom
K. Holmes, B. T. Johnson, Melanie G. Kirkpatrick
199746 citations
Semantic Scholar
Repurposing drugs to target the malaria parasite unfolding protein response
Yun Chen, Claribel Murillo-Solano, Melanie G. Kirkpatrick, T. Antoshchenko +2 more
2018Scientific Reports34 citations Open access
Semantic Scholar
Response to Hypoxia and the Ensuing Dysregulation of Inflammation Impacts Mycobacterium tuberculosis Pathogenicity
Allison N. Bucşan, Ashley V. Veatch, D. Singh, Sadia Akter +14 more
2022American Journal of Respiratory and Critical Care Medicine20 citations Open access
Semantic Scholar
Oral drug repositioning candidates and synergistic remdesivir combinations for the prophylaxis and treatment of COVID-19
M. Bakowski, N. Beutler, Emily Chen, Tu-Trinh H. Nguyen +11 more
2020bioRxiv19 citations Open access
Semantic Scholar
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead
N. G. R. Dayan Elshan, Karen C. Wolff, L. Riva, Ashley K. Woods +27 more
2024Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation.
C. Cadieux, C. Broomfield, Melanie G. Kirkpatrick, Meghan E. Kazanski +2 more
2010Chemico-Biological Interactions14 citations
Semantic Scholar
Electronic Reprint Structural Biology and Crystallization Communications Structure of Recombinant Human Carboxylesterase 1 Isolated from Whole Cabbage Looper Larvae Structural Biology and Crystallization Communications
Acta Crystallographica Section, H. Einspahr, M. Weiss, H. Greenblatt +7 more
9 citations
Semantic Scholar
Optimization of a micro-scale air–liquid-interface model of human proximal airway epithelium for moderate throughput drug screening for SARS-CoV-2
C. Sen, T. Rickabaugh, A. V. Jeyachandran, Constance Yuen +19 more
2025Respiratory Research4 citations Open access
Semantic Scholar
Open Source Repurposing Reveals Broad-Spectrum Antiviral Activity of Diphenylureas
U. A. K. Betz, Robert Garces, N. Beier, Sven Lindemann +12 more
2025Viruses2 citations Open access
Semantic Scholar
Astroviruses use mucus secretion as a novel form of viral egress
Natalie Pedicino, Melanie G. Kirkpatrick, Michelle Ann Pablo, Jacob Gulman +2 more
2026PLoS Pathogens1 citations Open access
Semantic Scholar
High Throughput Screening with a Primary Human Mucociliary Airway Model Identifies a Small Molecule with Anti-SARS-CoV-2 Activity
C. Sen, T. Rickabaugh, A. V. Jeyachandran, Constance Yuen +19 more
2024bioRxiv1 citations Open access
Semantic Scholar
Use of V agents and V-analogue compounds to probe the active site of atypical butyrylcholinesterase from Oryzias latipes.
Melanie G. Kirkpatrick, Robert C. diTargiani, R. Sweeney, Tamara C. Otto
2016Chemico-Biological Interactions1 citations Open access
Semantic Scholar
Escape from North Korea
Melanie G. Kirkpatrick
20121 citations
Semantic Scholar
Pan-Coronavirus Protease Engagement and Differentiated Pharmacology of Antiviral Candidate CMX990
N. G. R. Dayan Elshan, Karen C. Wolff, L. Riva, M. Bakowski +38 more
2026bioRxiv0 citations Open access
Semantic Scholar
Orally Bioavailable SARS-CoV-2 Protease Inhibitors Bearing a Hydroxymethyl Ketone Warhead
N. G. R. Dayan Elshan, Karen C. Wolff, Frank O. Weiss, Sourav Ghorai +30 more
2026bioRxiv0 citations Open access
Semantic Scholar
Correction to “Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead”
N. G. R. Dayan Elshan, Karen C. Wolff, L. Riva, Ashley K. Woods +28 more
2024Journal of Medicinal Chemistry0 citations Open access
Semantic Scholar
Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Covalent Warhead
N. G. R. Dayan Elshan, Karen C. Wolff, L. Riva, Ashley K. Woods +27 more
2023bioRxiv0 citations Open access
Semantic Scholar
Title: Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19
B. Boras, Rhys M. Jones, B. Anson, D. Arenson +45 more
20210 citations
Semantic Scholar
Use of V‐Agent Analogs to Probe the Active Site of Atypical Butyrylcholinesterase from Oryzias latipes
Melanie G. Kirkpatrick, R. Sweeney, Shane A. Kasten, Robert C. diTargiani +2 more
20150 citations
Semantic Scholar
Cracks in the Invisible (review)
Melanie G. Kirkpatrick
20120 citations
Semantic Scholar

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