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K. van Eunen · SciRah

Researcher profile · Semantic Scholar

K. van Eunen

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K. van Eunen — researcher profile on SciRah

h-index: 21
Works: 43
Citations: 7,548

Most-cited papers

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
G. den Besten, K. van Eunen, A. Groen, K. Venema +2 more
2013Journal of Lipid Research4,406 citations Open access
Semantic Scholar
Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation
G. den Besten, A. Bleeker, A. Gerding, K. van Eunen +7 more
2015Diabetes1,040 citations Open access
Semantic Scholar
Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids.
G. den Besten, K. Lange, R. Havinga, T. V. van Dijk +7 more
2013American Journal of Physiology - Gastrointestinal and Liver Physiology557 citations Open access
Semantic Scholar
A systems study reveals concurrent activation of AMPK and mTOR by amino acids
Piero Dalle Pezze, Stefanie Ruf, Annika G. Sonntag, M. Langelaar-Makkinje +16 more
2016Nature Communications313 citations Open access
Semantic Scholar
Measuring enzyme activities under standardized in vivo‐like conditions for systems biology
K. van Eunen, J. Bouwman, P. Daran-Lapujade, J. Postmus +15 more
2010The FEBS Journal208 citations Open access
Semantic Scholar
Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains.
A. Canelas, N. Harrison, Alessandro Fazio, Jie Zhang +31 more
2010Nature Communications127 citations Open access
Semantic Scholar
Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1
G. den Besten, A. Gerding, T. V. van Dijk, J. Ciapaite +6 more
2015PLoS ONE122 citations Open access
Semantic Scholar
Molecular mechanisms of mTOR regulation by stress
A. Heberle, M. T. Prentzell, K. van Eunen, B. Bakker +2 more
2014Molecular & Cellular Oncology100 citations Open access
Semantic Scholar
The Short-Chain Fatty Acid Uptake Fluxes by Mice on a Guar Gum Supplemented Diet Associate with Amelioration of Major Biomarkers of the Metabolic Syndrome
G. den Besten, R. Havinga, A. Bleeker, Shodhan Rao +5 more
2014PLoS ONE79 citations Open access
Semantic Scholar
Translational Targeted Proteomics Profiling of Mitochondrial Energy Metabolic Pathways in Mouse and Human Samples.
J. Wolters, J. Ciapaite, K. van Eunen, K. Niezen-Koning +6 more
2016Journal of Proteome Research55 citations
Semantic Scholar
Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Mitochondrial Targets to Treat Liver Fibrosis
Natalia Smith-Cortinez, K. van Eunen, J. Heegsma, S. Serna-Salas +5 more
2020Cells53 citations Open access
Semantic Scholar
Testing Biochemistry Revisited: How In Vivo Metabolism Can Be Understood from In Vitro Enzyme Kinetics
K. van Eunen, J. Kiewiet, H. Westerhoff, Barbara M. Bakker
2012PLoS Comput. Biol.50 citations Open access
Semantic Scholar
Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition
Catriona M Ling, Christian J Versloot, Matilda E. Arvidsson Kvissberg, Guanlan Hu +24 more
2023EBioMedicine41 citations Open access
Semantic Scholar
Metabolic regulation rather than de novo enzyme synthesis dominates the osmo‐adaptation of yeast
J. Bouwman, J. Kiewiet, A. Lindenbergh, K. van Eunen +2 more
2011Yeast39 citations
Semantic Scholar
Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids
P. Riemer, M. Rydenfelt, Matthias Marks, K. van Eunen +5 more
2017Journal of Cell Biology34 citations Open access
Semantic Scholar
Time‐dependent regulation analysis dissects shifts between metabolic and gene‐expression regulation during nitrogen starvation in baker’s yeast
K. van Eunen, J. Bouwman, A. Lindenbergh, H. Westerhoff +1 more
2009The FEBS Journal34 citations
Semantic Scholar
Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders
K. van Eunen, Catharina M. L. Volker-Touw, A. Gerding, A. Bleeker +10 more
2016BMC Biology33 citations Open access
Semantic Scholar
Full humanization of the glycolytic pathway in Saccharomyces cerevisiae.
F. J. Boonekamp, E. Knibbe, Marcel A. Vieira-Lara, M. Wijsman +11 more
2022Cell Reports29 citations Open access
Semantic Scholar
Time-dependent hierarchical regulation analysis: deciphering cellular adaptation.
F. Bruggeman, J. de Haan, H. Hardin, J. Bouwman +4 more
2006Systems biology28 citations
Semantic Scholar
SYSTEMS BIOLOGY FROM MICROORGANISMS TO HUMAN METABOLIC DISEASES – THE ROLE OF DETAILED KINETIC MODELS
Barbara M. Bakker, K. van Eunen, J. Jeneson, N. V. van Riel +2 more
2010Biochemical Society Transactions26 citations Open access
Semantic Scholar
Mixed and diverse metabolic and gene-expression regulation of the glycolytic and fermentative pathways in response to a HXK2 deletion in Saccharomyces cerevisiae.
S. Rossell, A. Lindenbergh, C. van der Weijden, A. Kruckeberg +3 more
2008FEMS Yeast Research26 citations Open access
Semantic Scholar
Impaired Very‐Low‐Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia
J. Hoogerland, Fabian Peeks, Brenda S. Hijmans, J. Wolters +16 more
2021Journal of Inherited Metabolic Disease22 citations Open access
Semantic Scholar
Enzyme kinetics for systems biology when, why and how.
M. Adamczyk, K. van Eunen, Barbara M. Bakker, H. Westerhoff
2011Methods in Enzymology20 citations
Semantic Scholar
Quantitative analysis of flux regulation through hierarchical regulation analysis.
K. van Eunen, S. Rossell, J. Bouwman, H. Westerhoff +1 more
2011Methods in Enzymology20 citations
Semantic Scholar
Time-dependent regulation of yeast glycolysis upon nitrogen starvation depends on cell history.
K. van Eunen, P. Dool, A. Canelas, J. Kiewiet +4 more
2010IET Systems Biology20 citations
Semantic Scholar
The discovAIR project: a roadmap towards the Human Lung Cell Atlas
M. Luecken, L. Zaragosi, E. Madissoon, L. Sikkema +36 more
2022European Respiratory Journal19 citations Open access
Semantic Scholar
Vertical systems biology: from DNA to flux and back.
A. Bevilacqua, S. J. Wilkinson, R. Dimelow, Ettore Murabito +10 more
2008SEB Experimental Biology Series19 citations
Semantic Scholar
Systems biochemistry in practice: experimenting with modelling and understanding, with regulation and control.
H. Westerhoff, Malkhey Verma, M. Nardelli, M. Adamczyk +3 more
2010Biochemical Society Transactions18 citations
Semantic Scholar
Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients
Christoff Odendaal, Emmalie A. Jager, Anne-Claire M. F. Martines, Marcel A. Vieira-Lara +8 more
2023BMC Biology10 citations Open access
Semantic Scholar
Precision-cut liver slices as an ex vivo model to assess impaired hepatic glucose production
L. A. Kiyuna, K. A. Krishnamurthy, E. Homan, Miriam Langelaar-Makkinje +11 more
2024Communications Biology5 citations Open access
Semantic Scholar
Phenylketonuria: modelling cerebral amino acid and neurotransmitter metabolism
Agnieszka B. Wegrzyn, D. van Vliet, K. van Eunen, M. Heiner-Fokkema +3 more
2025bioRxiv3 citations Open access
Semantic Scholar
The multifarious and dynamic regulation of the living cell
K. van Eunen
20103 citations
Semantic Scholar
Systems biology and the reconstruction of the cell: from molecular components to integral function.
F. Bruggeman, S. Rossell, K. van Eunen, J. Bouwman +2 more
2007Sub-cellular biochemistry3 citations
Semantic Scholar
Precision-cut liver slices as an ex vivo model to assess impaired hepatic glucose production
K. A. Krishnamurthy, L. A. Kiyuna, M. Langelaar, A. Gerding +6 more
2022Journal of Hepatology1 citations Open access
Semantic Scholar
A yeast with muscle doesn’t run faster: full humanization of the glycolytic pathway in Saccharomyces cerevisiae
F. J. Boonekamp, E. Knibbe, Marcel A. Vieira-Lara, M. Wijsman +11 more
20211 citations Open access
Semantic Scholar
Collective parameter estimation of related models with an initial stability constraint
P. Clark, Lea E Timpen, A. Heberle, Martina Prugger +4 more
2025bioRxiv0 citations
Semantic Scholar
Abstract PO-039: Combined in vivo13C-metabolomics and proteomics approach to optimise immunotherapy response in malignant melanoma
B. Evers, A. Gerding, J. Tiersma, K. van Eunen +4 more
20200 citations
Semantic Scholar
University of Groningen A model reduction method for biochemical reaction networks
Shodhan Rao, A. J. van der Schaft, K. van Eunen, B. Bakker +1 more
20170 citations
Semantic Scholar
Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders
K. van Eunen, Catharina M. L. Volker-Touw, A. Gerding, A. Bleeker +10 more
2016BMC Biology0 citations Open access
Semantic Scholar
University of Groningen The Short-Chain Fatty Acid Uptake Fluxes by Mice on a Guar Gum Supplemented Diet Associate with Amelioration of Major Biomarkers of the Metabolic Syndrome
G. den Besten, R. Havinga, A. Bleeker, Shodhan Rao +5 more
20140 citations
Semantic Scholar
Elucidating the mechanisms of action of short-chain fatty acids den Besten
G. den Besten, R. Havinga, Shodhan Rao, A. Gerding +4 more
20140 citations
Semantic Scholar
Gaining insight in the pathophysiology of medium-chain acyl-CoA dehydrogenase deficiency by studying a mouse model
C. M. Touw, K. van Eunen, N. Vink, K. Niezen-Koning +5 more
20140 citations
Semantic Scholar
The central role of mitochondrial health in malnutrition induced enterohepatic dysfunction
Christian J Versloot, Matilda E. Arvidsson Kvissberg, Catriona M Ling, Nathan Swain +18 more
0 citations
Semantic Scholar

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Barbara M. Bakker×21
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Barbara M. Bakker — researcher profile on SciRah
A. Gerding×14
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A. Gerding — researcher profile on SciRah
D. Reijngoud×12
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H. Westerhoff×11
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B. Bakker — researcher profile on SciRah

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J. Bouwman — researcher profile on SciRah

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A. Groen — researcher profile on SciRah

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J. Wolters — researcher profile on SciRah

G. den Besten×7

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G. den Besten — researcher profile on SciRah

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A. Bleeker — researcher profile on SciRah

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R. Havinga — researcher profile on SciRah

T. V. van Dijk×6

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T. V. van Dijk — researcher profile on SciRah