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Lir-Wan Fan · SciRah

Researcher profile · Semantic Scholar

Lir-Wan Fan

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Lir-Wan Fan — researcher profile on SciRah

h-index: 34
Works: 97
Citations: 3,346

Most-cited papers

Lipopolysaccharide-activated microglia induce death of oligodendrocyte progenitor cells and impede their development.
Y. Pang, Leigh R. Campbell, B. Zheng, Lir-Wan Fan +2 more
2010Neuroscience176 citations
Semantic Scholar
Minocycline alleviates hypoxic-ischemic injury to developing oligodendrocytes in the neonatal rat brain.
Zheng-Wei Cai, Shuying Lin, Lir-Wan Fan, Y. Pang +1 more
2006Neuroscience145 citations
Semantic Scholar
Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats
Shuying Lin, Lir-Wan Fan, P. Rhodes, Zheng-Wei Cai
2009Experimental Neurology144 citations Open access
Semantic Scholar
Minocycline reduces lipopolysaccharide‐induced neurological dysfunction and brain injury in the neonatal rat
Lir-Wan Fan, Y. Pang, Shuying Lin, Lu-Tai Tien +3 more
2005Journal of Neuroscience Research136 citations
Semantic Scholar
Hypoxia-ischemia induced neurological dysfunction and brain injury in the neonatal rat.
Lir-Wan Fan, Shuying Lin, Y. Pang, Man-Ping Lei +3 more
2005Behavioural Brain Research126 citations
Semantic Scholar
IGF‐1 protects oligodendrocyte progenitors against TNFα‐induced damage by activation of PI3K/Akt and interruption of the mitochondrial apoptotic pathway
Y. Pang, B. Zheng, Lir-Wan Fan, P. Rhodes +1 more
2007Glia122 citations
Semantic Scholar
Minocycline attenuates lipopolysaccharide-induced white matter injury in the neonatal rat brain.
Lir-Wan Fan, Y. Pang, Shuying Lin, P. Rhodes +1 more
2005Neuroscience120 citations
Semantic Scholar
Minocycline attenuates hypoxia–ischemia‐induced neurological dysfunction and brain injury in the juvenile rat
Lir-Wan Fan, Shuying Lin, Y. Pang, P. Rhodes +1 more
2006European Journal of Neuroscience108 citations
Semantic Scholar
Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats
Y. Pang, Shuying Lin, C. Wright, Juying Shen +3 more
2016Neuroscience95 citations Open access
Semantic Scholar
Butorphanol: effects of a prototypical agonist-antagonist analgesic on kappa-opioid receptors.
Stephen Commiskey, Lir-Wan Fan, I. Ho, R. Rockhold
2005Journal of Pharmacological Sciences95 citations Open access
Semantic Scholar
Neonatal lipopolysaccharide exposure induces long-lasting learning impairment, less anxiety-like response and hippocampal injury in adult rats
Kuo-Ching Wang, Lir-Wan Fan, Asuka Kaizaki, Y. Pang +2 more
2013Neuroscience94 citations Open access
Semantic Scholar
IGF-1 protects oligodendrocyte progenitor cells and improves neurological functions following cerebral hypoxia-ischemia in the neonatal rat.
Shuying Lin, Lir-Wan Fan, Y. Pang, P. Rhodes +2 more
2005Brain Research94 citations
Semantic Scholar
Differential roles of astrocyte and microglia in supporting oligodendrocyte development and myelination in vitro
Y. Pang, Lir-Wan Fan, Lu-Tai Tien, Xuemei Dai +4 more
2013Brain and Behavior90 citations Open access
Semantic Scholar
Dopaminergic neuronal injury in the adult rat brain following neonatal exposure to lipopolysaccharide and the silent neurotoxicity
Lir-Wan Fan, Lu-Tai Tien, B. Zheng, Y. Pang +5 more
2010Brain, behavior, and immunity73 citations Open access
Semantic Scholar
Dysregulation of neurogenesis by neuroinflammation: key differences in neurodevelopmental and neurological disorders
Lir-Wan Fan, Y. Pang
2017Neural Regeneration Research68 citations Open access
Semantic Scholar
Exposure to serotonin adversely affects oligodendrocyte development and myelination in vitro
Lir-Wan Fan, A. Bhatt, Lu-Tai Tien, B. Zheng +5 more
2015Journal of Neurochemistry64 citations Open access
Semantic Scholar
The interaction of morphine and γ-aminobutyric acid (GABA)ergic systems in anxiolytic behavior: Using μ-opioid receptor knockout mice
K. Sasaki, Lir-Wan Fan, Tai-Tien Lu, T. Ma +2 more
200262 citations
Semantic Scholar
Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide
Asuka Kaizaki, Lu-Tai Tien, Y. Pang, Zheng-Wei Cai +4 more
2013Journal of Neuroinflammation61 citations Open access
Semantic Scholar
IGF-1 can either protect against or increase LPS-induced damage in the developing rat brain
Y. Pang, B. Zheng, Leigh R. Campbell, Lir-Wan Fan +2 more
2010Pediatric Research61 citations Open access
Semantic Scholar
Maternal immune activation alters fetal and neonatal microglia phenotype and disrupts neurogenesis in mice
Marco Loayza, Shuying Lin, Kathleen Carter, N. Ojeda +4 more
2022Pediatric Research58 citations
Semantic Scholar
Early Postnatal Lipopolysaccharide Exposure Leads to Enhanced Neurogenesis and Impaired Communicative Functions in Rats
Y. Pang, Xue-Mei Dai, Anna M. Roller, Kathleen Carter +4 more
2016PLoS ONE55 citations Open access
Semantic Scholar
α‐Phenyl‐n‐tert‐butyl‐nitrone ameliorates hippocampal injury and improves learning and memory in juvenile rats following neonatal exposure to lipopolysaccharide
Lir-Wan Fan, Lu-Tai Tien, Helen J. Mitchell, P. Rhodes +1 more
2008European Journal of Neuroscience55 citations
Semantic Scholar
Role of interleukin-6 in lipopolysaccharide-induced brain injury and behavioral dysfunction in neonatal rats.
Y. Pang, Lir-Wan Fan, B. Zheng, Zheng-Wei Cai +1 more
2006Neuroscience54 citations
Semantic Scholar
Rapid transport of insulin to the brain following intranasal administration in rats
Lir-Wan Fan, Kathleen Carter, A. Bhatt, Y. Pang
2019Neural Regeneration Research53 citations Open access
Semantic Scholar
Intranasal Administration of IGF-1 Protects against Lipopolysaccharide-induced Injury in the Developing Rat Brain
Zheng-Wei Cai, Lir-Wan Fan, Shuying Lin, Y. Pang +1 more
2011Neuroscience51 citations Open access
Semantic Scholar
Association between normal tension glaucoma and the risk of Alzheimer’s disease: a nationwide population-based cohort study in Taiwan
Yu-Yen Chen, Y. Lai, Y. Yen, Ying-Cheng Shen +4 more
2018BMJ Open50 citations Open access
Semantic Scholar
Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life
Lir-Wan Fan, Lu-Tai Tien, R. C. Lin, K. Simpson +2 more
2011Neurobiology of Disease47 citations Open access
Semantic Scholar
Erythropoietin Ameliorates Neonatal Hypoxia-Ischemia-Induced Neurobehavioral Deficits, Neuroinflammation, and Hippocampal Injury in the Juvenile Rat
Kuo-Mao Lan, Lu-Tai Tien, Zheng-Wei Cai, Shuying Lin +6 more
2016International Journal of Molecular Sciences45 citations Open access
Semantic Scholar
Neonatal systemic exposure to lipopolysaccharide enhances susceptibility of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life
Zheng-Wei Cai, Lir-Wan Fan, Asuka Kaizaki, Lu-Tai Tien +5 more
2013Developmental Neuroscience44 citations Open access
Semantic Scholar
INTERLEUKIN-1β-INDUCED BRAIN INJURY AND NEUROBEHAVIORAL DYSFUNCTIONS IN JUVENILE RATS CAN BE ATTENUATED BY α-PHENYL-N-TERT-BUTYL-NITRONE
Lir-Wan Fan, Lu-Tai Tien, B. Zheng, Y. Pang +2 more
2010Neuroscience41 citations Open access
Semantic Scholar
α-Phenyl-n-tert-butyl-nitrone Attenuates Lipopolysaccharide-induced Brain Injury and Improves Neurological Reflexes and Early Sensorimotor Behavioral Performance in Juvenile Rats
Lir-Wan Fan, Ruei-Feng Chen, Helen J. Mitchell, R. C. Lin +3 more
2008Journal of Neuroscience Research41 citations Open access
Semantic Scholar
Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats
Cheng T. Hsieh, Yih-Jing Lee, Xiaoli Dai, N. Ojeda +3 more
2018International Journal of Molecular Sciences39 citations Open access
Semantic Scholar
Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats
Chih-Shung Wong, G. Jow, Asuka Kaizaki, Lir-Wan Fan +1 more
2014Neuroscience37 citations Open access
Semantic Scholar
Increased dopamine D2 receptor binding and enhanced apomorphine-induced locomotor activity in mu-opioid receptor knockout mice.
Lu-Tai Tien, Younjoo Park, Lir-Wan Fan, T. Ma +2 more
2003Brain Research Bulletin37 citations
Semantic Scholar
Strategies for myelin regeneration: lessons learned from development
A. Bhatt, Lir-Wan Fan, Y. Pang
2014Neural Regeneration Research34 citations Open access
Semantic Scholar
Neuroprotective effects of intranasal IGF-1 against neonatal lipopolysaccharide-induced neurobehavioral deficits and neuronal inflammation in the substantia nigra and locus coeruleus of juvenile rats
Lu-Tai Tien, Yih-Jing Lee, Y. Pang, Silu Lu +5 more
2017Developmental Neuroscience32 citations Open access
Semantic Scholar
Convolutional block attention autoencoder for denoising electrocardiograms
Wesley Chorney, Haifeng Wang, Lu He, Seung-Han Lee +1 more
2023Biomedical Signal Processing and Control30 citations
Semantic Scholar
Interleukin-1β-induced brain injury in the neonatal rat can be ameliorated by α-phenyl-n-tert-butyl-nitrone
Lir-Wan Fan, H. Mitchell, Lu-Tai Tien, P. Rhodes +1 more
2009Experimental Neurology30 citations Open access
Semantic Scholar
Interleukin-1 Receptor Antagonist Reduces Neonatal Lipopolysaccharide-Induced Long-Lasting Neurobehavioral Deficits and Dopaminergic Neuronal Injury in Adult Rats
Y. Pang, Lu-Tai Tien, Hobart Zhu, Juying Shen +6 more
2015International Journal of Molecular Sciences29 citations Open access
Semantic Scholar
Interleukin-1 receptor antagonist ameliorates neonatal lipopolysaccharide-induced long-lasting hyperalgesia in the adult rats
Kuo-Ching Wang, Su-Jane Wang, Lir-Wan Fan, Zheng-Wei Cai +2 more
2010Toxicology29 citations Open access
Semantic Scholar
Region specific increase of dopamine receptor D1/D2 mRNA expression in the brain of μ-opioid receptor knockout mice
Younjoo Park, I. Ho, Lir-Wan Fan, H. Loh +1 more
200129 citations
Semantic Scholar
Functionalized Collagen/Elastin‐like Polypeptide Hydrogels for Craniofacial Bone Regeneration
Pallabi Pal, M. Tucci, Lir-Wan Fan, Ratna Bollavarapu +3 more
2022Advanced Healthcare Materials27 citations
Semantic Scholar
Effect of prenatal methadone on reinstated behavioral sensitization induced by methamphetamine in adolescent rats.
Chih-Shung Wong, Yih-Jing Lee, Yao-Chang Chiang, Lir-Wan Fan +2 more
2014Behavioural Brain Research27 citations Open access
Semantic Scholar
α‐Phenyl‐n‐tert‐butyl‐nitrone reduces lipopolysaccharide‐induced white matter injury in the neonatal rat brain
Lir-Wan Fan, Helen J. Mitchell, Lu-Tai Tien, B. Zheng +3 more
200827 citations
Semantic Scholar
IL-1 receptor antagonist attenuates neonatal lipopolysaccharide-induced long-lasting learning impairment and hippocampal injury in adult rats
Kuo-Mao Lan, Lu-Tai Tien, Y. Pang, A. Bhatt +1 more
2015Toxicology Letters26 citations Open access
Semantic Scholar
Interleukin-1 receptor antagonist ameliorates the pain hypersensitivity, spinal inflammation and oxidative stress induced by systemic lipopolysaccharide in neonatal rats
Cheng T. Hsieh, Yih-Jing Lee, Jonathan W. Lee, Silu Lu +6 more
2020Neurochemistry International25 citations Open access
Semantic Scholar
Alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced neuronal injury in the neonatal rat brain.
Lir-Wan Fan, Helen J. Mitchell, P. Rhodes, Zheng-Wei Cai
2008Neuroscience25 citations Open access
Semantic Scholar
Changes in acetylcholinesterase activity and muscarinic receptor bindings in mu-opioid receptor knockout mice.
Lu-Tai Tien, Lir-Wan Fan, C. Sogawa, T. Ma +2 more
2004Brain Research. Molecular Brain Research25 citations Open access
Semantic Scholar
The interaction of morphine and gamma-aminobutyric acid (GABA)ergic systems in anxiolytic behavior: using mu-opioid receptor knockout mice.
K. Sasaki, Lir-Wan Fan, Tai-Tien Lu, T. Ma +2 more
2002Brain Research Bulletin24 citations
Semantic Scholar
Pioglitazone Ameliorates Lipopolysaccharide-Induced Behavioral Impairment, Brain Inflammation, White Matter Injury and Mitochondrial Dysfunction in Neonatal Rats
Jiann-Horng Yeh, Kuo-Ching Wang, Asuka Kaizaki, Jonathan W. Lee +5 more
2021International Journal of Molecular Sciences21 citations Open access
Semantic Scholar

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Y. Pang×29
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Y. Pang — researcher profile on SciRah
Zheng-Wei Cai×28
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Lu-Tai Tien×24
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Shuying Lin — researcher profile on SciRah

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T. Ma — researcher profile on SciRah

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R. C. Lin — researcher profile on SciRah

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Helen J. Mitchell — researcher profile on SciRah