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A. Foster · SciRah

Researcher profile · Semantic Scholar

A. Foster

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A. Foster — researcher profile on SciRah

h-index: 49
Works: 149
Citations: 10K

Most-cited papers

Gene expression analyses reveal molecular relationships among 20 regions of the human CNS
R. Roth, P. Hevezi, Jerry Lee, D. Willhite +3 more
2006Neurogenetics367 citations
Semantic Scholar
Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors.
F. Sajjadi, K. Takabayashi, A. Foster, R. C. Domingo +1 more
1996Journal of Immunology367 citations
Semantic Scholar
Glutamate- and GABA-based CNS therapeutics.
A. Foster, J. Kemp
2006Current opinion in pharmacology (Print)229 citations
Semantic Scholar
Corticotropin Releasing Hormone Type 2 Receptors in the Dorsal Raphe Nucleus Mediate the Behavioral Consequences of Uncontrollable Stress
S. E. Hammack, M. J. Schmid, M. LoPresti, A. Der-Avakian +4 more
2003Journal of Neuroscience187 citations Open access
Semantic Scholar
4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor.
P. Leeson, R. Carling, K. Moore, A. Moseley +6 more
1992Journal of Medicinal Chemistry167 citations Open access
Semantic Scholar
Pharmacological evidence supporting a role for central corticotropin-releasing factor(2) receptors in behavioral, but not endocrine, response to environmental stress.
M. Pelleymounter, M. Joppa, N. Ling, A. Foster
2002Journal of Pharmacology and Experimental Therapeutics157 citations
Semantic Scholar
High-Affinity CRF1 Receptor Antagonist NBI-34041: Preclinical and Clinical Data Suggest Safety and Efficacy in Attenuating Elevated Stress Response
M. Ising, U. Zimmermann, H. Künzel, M. Uhr +4 more
2007Neuropsychopharmacology137 citations
Semantic Scholar
Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists.
M. Rowley, J. J. Kulagowski, Alan P. Watt, D. Rathbone +12 more
1997Journal of Medicinal Chemistry137 citations
Semantic Scholar
Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor.
P. Leeson, R. Baker, R. Carling, N. Curtis +6 more
1991Journal of Medicinal Chemistry130 citations
Semantic Scholar
Behavioral and neuroendocrine effects of the selective CRF2 receptor agonists urocortin II and urocortin III.
M. Pelleymounter, M. Joppa, Nick Ling, A. Foster
2004Peptides116 citations
Semantic Scholar
3'-(Arylmethyl)- and 3'-(aryloxy)-3-phenyl-4-hydroxyquinolin-2(1H)-ones: orally active antagonists of the glycine site on the NMDA receptor.
J. Kulagowski, R. Baker, N. Curtis, P. Leeson +6 more
1994Journal of Medicinal Chemistry114 citations Open access
Semantic Scholar
Indiplon Is a High-Affinity Positive Allosteric Modulator with Selectivity for α1 Subunit-Containing GABAA Receptors
R. Petroski, Jordan E. Pomeroy, Ronnie Das, H. Bowman +3 more
2006Journal of Pharmacology and Experimental Therapeutics112 citations
Semantic Scholar
Urocortin, corticotropin releasing factor-2 receptors and energy balance.
M. J. Cullen, Nick Ling, A. Foster, M. Pelleymounter
2001Endocrinology106 citations Open access
Semantic Scholar
Delayed treatment with an adenosine kinase inhibitor, GP683, attenuates infarct size in rats with temporary middle cerebral artery occlusion.
T. Tatlisumak, K. Takano, R. Carano, L. Miller +2 more
1998Stroke98 citations Open access
Semantic Scholar
Adenosine kinase inhibitors as a novel approach to anticonvulsant therapy.
J. Wiesner, B. Ugarkar, A. Castellino, J. Barankiewicz +4 more
1999Journal of Pharmacology and Experimental Therapeutics95 citations
Semantic Scholar
Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke.
Sarah A. Loddick, Xin-Jun Liu, Zi-Xian Lu, Chang-Lu Liu +6 more
1998Proceedings of the National Academy of Sciences of the United States of America95 citations Open access
Semantic Scholar
The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist.
S. Markison, A. Foster, Chen Chen, G. Brookhart +5 more
2005Endocrinology93 citations Open access
Semantic Scholar
2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor.
R. Carling, P. Leeson, A. Moseley, R. Baker +4 more
1992Journal of Medicinal Chemistry80 citations
Semantic Scholar
3-Nitro-3,4-dihydro-2(1H)-quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
R. Carling, P. Leeson, K. Moore, J. Smith +6 more
1993Journal of Medicinal Chemistry72 citations Open access
Semantic Scholar
D-Serine Is a Substrate for Neutral Amino Acid Transporters ASCT1/SLC1A4 and ASCT2/SLC1A5, and Is Transported by Both Subtypes in Rat Hippocampal Astrocyte Cultures
A. Foster, Jill Farnsworth, G. Lind, Yong-Xin Li +6 more
2016PLoS ONE67 citations Open access
Semantic Scholar
Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice.
W. Cheung, Huey-Ju Kuo, S. Markison, Cheng Chen +3 more
2007Journal of the American Society of Nephrology67 citations
Semantic Scholar
In Vivo Pharmacological Characterization of Indiplon, a Novel Pyrazolopyrimidine Sedative-Hypnotic
A. Foster, M. Pelleymounter, M. J. Cullen, Dacie R. Lewis +5 more
2004Journal of Pharmacology and Experimental Therapeutics66 citations
Semantic Scholar
Central infusion of the melanocortin receptor antagonist agouti-related peptide (AgRP(83-132)) prevents cachexia-related symptoms induced by radiation and colon-26 tumors in mice.
M. Joppa, K. Gogas, A. Foster, S. Markison
2007Peptides63 citations
Semantic Scholar
Identification of differentially expressed genes induced by transient ischemic stroke.
David A. Schwarz, G. Barry, K. B. Mackay, F. Manu +6 more
2002Brain Research. Molecular Brain Research63 citations
Semantic Scholar
Neuroprotective Effects of Insulin-Like Growth Factor-Binding Protein Ligand Inhibitors in Vitro and in Vivo
K. B. Mackay, Sarah A. Loddick, G. Naeve, A. Vana +2 more
2003Journal of Cerebral Blood Flow and Metabolism62 citations Open access
Semantic Scholar
Characterization of Novel Aryl-Ether, Biaryl, and Fluorene Aspartic Acid and Diaminopropionic Acid Analogs as Potent Inhibitors of the High-Affinity Glutamate Transporter EAAT2
J. Dunlop, H. Beal McIlvain, T. Carrick, B. Jow +10 more
2005Molecular Pharmacology56 citations Open access
Semantic Scholar
Characterization of the Interaction of Indiplon, a Novel Pyrazolopyrimidine Sedative-Hypnotic, with the GABAA Receptor
Susan K. Sullivan, R. Petroski, G. Verge, R. Gross +2 more
2004Journal of Pharmacology and Experimental Therapeutics52 citations Open access
Semantic Scholar
Pre- and peristroke treatment with the adenosine kinase inhibitor, 5'-deoxyiodotubercidin, significantly reduces infarct volume after temporary occlusion of the middle cerebral artery in rats.
L. Miller, Laura A. Jelovich, Li-Ping Yao, Jay Dare +2 more
1996Neuroscience Letters50 citations
Semantic Scholar
Corticotropin‐releasing factor receptor 1‐deficient mice show decreased anxiety and colonic sensitivity
N. Trimble, A. Johnson, A. Foster, B. Meerveld
2007Neurogastroenterology and Motility49 citations
Semantic Scholar
BDNF, NT-3 and Trk receptor agonist monoclonal antibodies promote neuron survival, neurite extension, and synapse restoration in rat cochlea ex vivo models relevant for hidden hearing loss
S. Szobota, P. Mathur, Sairey Siegel, Kristenann Black +2 more
2019PLoS ONE47 citations Open access
Semantic Scholar
[3H]MK‐801 Binding to N‐Methyl‐d‐Aspartate Receptors Solubilized from Rat Brain: Effects of Glycine Site Ligands, Polyamines, Ifenprodil, and Desipramine
Margot H. M. Bakker, R. Mckernan, E. H. F. Wong, A. Foster
1991Journal of Neurochemistry44 citations
Semantic Scholar
Allosteric modulation of the glutamate site on the NMDA receptor by four novel glycine site antagonists.
Sarah Grimwood, J. J. Kulagowski, I. Mawer, M. Rowley +2 more
1995European Journal of Pharmacology41 citations
Semantic Scholar
The expression of excitatory amino acid binding sites during neuritogenesis in the developing rat cerebellum.
M. Cambray-Deakin, A. Foster, Robert D. Burgoyne
1990Brain research. Developmental brain research39 citations
Semantic Scholar
[3H]glycine uptake in rat hippocampus: kinetic analysis and autoradiographic localization.
Ernesto Fedele, A. Foster
1992Brain Research34 citations
Semantic Scholar
Effects of a selective agonist and antagonist of CRF2 receptors on cardiovascular function in the rat.
K. B. Mackay, Theodore H. Stiefel, Nick Ling, A. Foster
2003European Journal of Pharmacology32 citations
Semantic Scholar
Pharmacological characterization of threo‐3‐methylglutamic acid with excitatory amino acid transporters in native and recombinant systems
S. Eliasof, H. Beal McIlvain, Robert E. Petroski, A. Foster +1 more
2001Journal of Neurochemistry31 citations
Semantic Scholar
4-{(2R)-[3-Aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl}-1-{2-[(2-thienyl)ethylaminomethyl]phenyl}piperazine as a potent and selective melanocortin-4 receptor antagonist--design, synthesis, and characterization.
Chen Chen, Joseph Pontillo, Beth A. Fleck, Yinghong Gao +6 more
2004Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Phenylglycine analogs are inhibitors of the neutral amino acid transporters ASCT1 and ASCT2 and enhance NMDA receptor‐mediated LTP in rat visual cortex slices
A. Foster, Natalie Rangel-Diaz, U. Staubli, Jia-Ying Yang +3 more
2017Neuropharmacology27 citations
Semantic Scholar
Melanocortin-4 receptor antagonists as potential therapeutics in the treatment of cachexia.
A. Foster, Cheng Chen
2007Current Topics in Medicinal Chemistry27 citations
Semantic Scholar
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines.
F. Tucci, Nicole S. White, S. Markison, M. Joppa +15 more
2005Bioorganic & Medicinal Chemistry Letters26 citations
Semantic Scholar
Expression of rat insulin-like growth factor binding protein-6 in the brain, spinal cord, and sensory ganglia.
Gregory S. Naeve, A. Vana, Joelle R. Eggold, Gail M. Verge +2 more
2000Brain Research. Molecular Brain Research26 citations
Semantic Scholar
Molecular interactions of nonpeptide agonists and antagonists with the melanocortin-4 receptor.
Beth A. Fleck, Chen Chen, Weidong Yang, Rajesh Huntley +4 more
2005Biochemistry25 citations
Semantic Scholar
Studies on the structure-activity relationship of bicifadine analogs as monoamine transporter inhibitors.
Ming-Zhu Zhang, F. Jovic, Troy D. Vickers, Brian P. Dyck +7 more
2008Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Amino acid bioisosteres: design of 2-quinolone derivatives as glycine-site N-methyl-D-aspartate receptor antagonists
P. Leeson, R. Baker, R. Carling, J. J. Kulagowski +8 more
199324 citations
Semantic Scholar
A neurotrophic approach to treating hearing loss: Translation from animal models to clinical proof-of-concept.
A. Foster, S. Szobota, F. Piu, Bonnie E. Jacques +3 more
2022Journal of the Acoustical Society of America23 citations Open access
Semantic Scholar
A Novel Cell-Based Assay for G-Protein-Coupled Receptor-Mediated Cyclic Adenosine Monophosphate Response Element Binding Protein Phosphorylation
J. Selkirk, Lisa M. Nottebaum, Ian Ford, Mark A Santos +3 more
2006Journal of biomolecular screening23 citations Open access
Semantic Scholar
Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor.
Joseph Pontillo, Joe A. Tran, Beth A. Fleck, Dragan Marinkovic +9 more
2004Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Structure-activity relationships of piperazinebenzylamines as potent and selective agonists of the human melanocortin-4 receptor.
Joseph Pontillo, Joe A. Tran, M. Arellano, Beth A. Fleck +12 more
2004Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Neuroprotective Effects of the CRF1 Antagonist R121920 after Permanent Focal Ischemia in the Rat
K. B. Mackay, H. Bozigian, D. Grigoriadis, Sarah A. Loddick +2 more
2001Journal of Cerebral Blood Flow and Metabolism21 citations
Semantic Scholar
Pharmacological and pharmacokinetic characterization of 2-piperazine-alpha-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists.
Chen Chen, F. Tucci, Wanlong Jiang, Joe A. Tran +14 more
2008Bioorganic & Medicinal Chemistry20 citations Open access
Semantic Scholar

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