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B. Fitzsimmons · SciRah

Researcher profile · Semantic Scholar

B. Fitzsimmons

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B. Fitzsimmons — researcher profile on SciRah

h-index: 22
Works: 64
Citations: 1,263

Most-cited papers

The total synthesis of ionophore antibiotics. A convergent synthesis of lasalocid A (X537A)
R. Ireland, R. Anderson, R. Badoud, B. Fitzsimmons +3 more
1983138 citations
Semantic Scholar
The total synthesis of 12-HETE (12-hydroxyeicosatetraenoic acid) and 12,20-diHETE
Y. Leblanc, B. Fitzsimmons, Julian Adams, F. Perez +1 more
198682 citations
Semantic Scholar
Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase.
D. Nathaniel, Jillian F. Evans, Y. Leblanc, C. Lévéille +2 more
1985Biochemical and Biophysical Research Communications - BBRC70 citations
Semantic Scholar
Enantiospecific and stereospecific synthesis of lipoxin A. Stereochemical assignment of the natural lipoxin A and its possible biosynthesis
Julian Adams, B. Fitzsimmons, Y. Girard, Y. Leblanc +2 more
198562 citations
Semantic Scholar
Formation of lipoxin B by the pure reticulocyte lipoxygenase via sequential oxygenation of the substrate.
Hartmut Kühn, R. Wiesner, L. Alder, B. Fitzsimmons +2 more
1987European Journal of Biochemistry61 citations Open access
Semantic Scholar
[4 + 2] cycloaddition reaction of dibenzyl azodicarboxylate and glycals
Y. Leblanc, B. Fitzsimmons, J. P. Springer, J. Rokach
198948 citations
Semantic Scholar
Activation of leukocyte movement and displacement of [3H]leukotriene B4 from leukocyte membrane preparations by (12R)- and (12S)-hydroxyeicosatetraenoic acid.
Jillian F. Evans, Y. Leblanc, B. Fitzsimmons, S. Charleson +2 more
1987Biochimica et Biophysica Acta47 citations
Semantic Scholar
The lipoxins. Stereochemical identification and determination of their biosynthesis.
B. Fitzsimmons, J. Adams, Jillian F. Evans, Y. Leblanc +1 more
1985Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes.
Natsuo Ueda, C. Yokoyama, Shozo Yamamoto, B. Fitzsimmons +3 more
1987Biochemical and Biophysical Research Communications - BBRC44 citations
Semantic Scholar
[4+2] Cycloaddition of azodicarboxylate and glycals: a novel and simple method for the preparation of 2-amino-2-deoxy carbohydrates
B. Fitzsimmons, Y. Leblanc, J. Rokach
198744 citations
Semantic Scholar
Stereochemical requirements for substrate specificity of LTB4 20-hydroxylase.
R. Soberman, R. Okita, B. Fitzsimmons, J. Rokach +2 more
1987Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Total synthesis of polyether antibiotics. Synthesis of the enantiomer of lasalocid A (X-537A)
R. Ireland, L. F. Courtney, B. Fitzsimmons
198337 citations
Semantic Scholar
[4+2] Cycloaddition reaction of bis (trichloroethyl) azodicarboxylate and glycals: preparation of a C1-C1 2-amino disaccharide
Y. Leblanc, B. Fitzsimmons
198933 citations
Semantic Scholar
Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase.
Cheuk K. Lau, P. Bélanger, C. Dufresne, J. Scheigetz +6 more
1992Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Total synthesis of lipoxin B: assignment of stereochemistry
Y. Leblanc, B. Fitzsimmons, Julian Adams, J. Rokach
198529 citations
Semantic Scholar
Preparation of Complex Aminoglycosides: A New Strategy.
B. Fitzsimmons, Y. Leblanc, N. Chan, J. Rokach
198827 citations
Semantic Scholar
Leukotriene B3, leukotriene B4 and leukotriene B5; binding to leukotriene B4 receptors on rat and human leukocyte membranes.
S. Charleson, Jillian F. Evans, R. Zamboni, Y. Leblanc +4 more
1986Prostaglandins27 citations
Semantic Scholar
Synthetic routes to 6,8-dioxabicyclo[3.2.1]octyl pheromones from D-glucose derivatives. 4. Synthesis of (-)-.alpha.-multistriatin
Dieter E. Plaumann, B. Fitzsimmons, B. Ritchie, B. Fraser-Reid
198227 citations
Semantic Scholar
Synthesis of lipoxins: Total synthesis of conjugated trihydroxy eicosatetraenoic acids
Julian Adams, B. Fitzsimmons, J. Rokach
198525 citations
Semantic Scholar
The in vivo production of peptide leukotrienes after pulmonary anaphylaxis in the rat.
A. Foster, G. Letts, S. Charleson, B. Fitzsimmons +2 more
1988Journal of Immunology24 citations
Semantic Scholar
Justicidin E: A new leukotriene biosynthesis inhibitor.
M. Thérien, B. Fitzsimmons, J. Scheigets, D. Macdonald +4 more
199323 citations
Semantic Scholar
Metabolism and excretion of peptide leukotrienes in the anesthetized rat.
A. Foster, B. Fitzsimmons, Joshua Rokach, L. Letts
1987Biochimica et Biophysica Acta23 citations
Semantic Scholar
A chiral synthesis of the left-side aldehyde for lasalocid A synthesis
R. Ireland, G. Mcgarvey, R. Anderson, R. Badoud +2 more
198022 citations
Semantic Scholar
Evidence of in-vivo omega-oxidation of peptide leukotrienes in the rat: biliary excretion of 20-CO2H N-acetyl LTE4.
A. Foster, B. Fitzsimmons, Joshua Rokach, Gordon Letts
1987Biochemical and Biophysical Research Communications - BBRC21 citations
Semantic Scholar
Analogs of leukotriene B4: effects of modification of the hydroxyl groups on leukocyte aggregation and binding to leukocyte leukotriene B4 receptors.
Y. Leblanc, B. Fitzsimmons, S. Charleson, P. Alexander +2 more
1987Prostaglandins19 citations
Semantic Scholar
ANNULATED PYRANOSIDES ‐ V. AN ENANTIOSPECIFIC ROUTE TO (+)‐ AND (‐)‐CHRYSANTHEMUM DICARBOXYLIC ACIDS
B. Fitzsimmons, B. Fraser-Reid
198419 citations
Semantic Scholar
Biochemical Studies on Mammalian Lipoxygenases a , b
Shozo Yamamoto, N. Ueda, H. Ehara, T. Maruyama +9 more
198817 citations
Semantic Scholar
Annulated pyranosides—V
B. Fitzsimmons, B. Fraser-Reid
198417 citations
Semantic Scholar
The synthesis of N-acetyl-leukotriene E4 and its effects on cardiovascular and respiratory function of the anesthetized pig.
A. Foster, B. Fitzsimmons, L. Letts
1986Prostaglandins16 citations
Semantic Scholar
Annulated pyranosides as chiral synthons for carbocyclic systems. Enantiospecific routes to both (+)- and (-)-chrysanthemumdicarboxylic acids from a single progenitor
B. Fitzsimmons, B. Fraser-Reid
197916 citations
Semantic Scholar
The synthesis of 5-O-benzoyl-14,15-didehydro-leukotriene B4 (LTB4) ethyl ester and 5-O-benzoyl-14,15-didehydro-20-hydroxy-leukotriene B4 (LTB4) ethyl ester: The direct precursors of labelled LTB4's
Y. Leblanc, B. Fitzsimmons, R. Zamboni, J. Rokach
198815 citations
Semantic Scholar
On the biosynthesis and the structure of lipoxin B
B. Fitzsimmons, J. Rokach
198515 citations
Semantic Scholar
Synthesis of 5S-hydroxy-14, 15 LTA4 a biogenic precursor to the lipoxins
Y. Leblanc, B. Fitzsimmons, J. Rokach, N. Ueda +1 more
198714 citations
Semantic Scholar
Neutrophil LTA4 hydrolases and leukotriene B4 receptors: effects of leukotriene epoxides and their enzymatic products.
J. Evans, D. Nathaniel, S. Charleson, C. Láveillé +7 more
1986Prostaglandins Leukotrienes and Medicine13 citations
Semantic Scholar
Lipoxin syntheses by arachidonate 12- and 5-lipoxygenases purified from porcine leukocytes.
Shozo Yamamoto, Natsuo Ueda, C. Yokoyama, B. Fitzsimmons +3 more
1988Advances in Experimental Medicine and Biology10 citations
Semantic Scholar
Biological activities of isomers of 8,15-dihydroxyeicosatetraenoic acid.
J. Evans, A. Ford-Hutchinson, B. Fitzsimmons, Joshua Rokach
1984Prostaglandins10 citations
Semantic Scholar
The total syntheses of several 8, 15 dihydroxy arachidonic acid derivatives (8,15, LTB's)
B. Fitzsimmons, J. Rokach
19849 citations
Semantic Scholar
Ciral synthons for the multistriatins
B. Fitzsimmons, Dieter E. Plaumann, B. Fraser-Reid
19798 citations
Semantic Scholar
ANNULATED PYRANOSIDES AS CHIRAL SYNTHONS FOR CARBOCYCLIC SYSTEMS. ENANTIOSPECIFIC ROUTES TO BOTH (+)‐ AND (‐)‐CHRYSANTHEMUMDICARBOXYLIC ACIDS FROM A SINGLE PROGENITOR
B. Fitzsimmons, B. Fraser-Reid
19807 citations
Semantic Scholar
Lipoxin synthesis by arachidonate 5-lipoxygenase purified from porcine leukocytes.
Natsuo Ueda, Shozo Yamamoto, B. Fitzsimmons, J. Rokach
1987Biochemical and Biophysical Research Communications - BBRC6 citations
Semantic Scholar
Leukotrienes and Lipoxins: Synthesis and Biosynthesis
J. Rokach, B. Fitzsimmons, Y. Leblanc, N. Ueda +2 more
19894 citations
Semantic Scholar
The Total Synthesis of 12-HETE (I) and 12,20-DiHETE (II).
Y. Leblanc, B. Fitzsimmons, Julian Adams, F. Perez +1 more
19864 citations
Semantic Scholar
Lipoxygenase Inhibitors and Leukotriene Receptor Antagonists
B. Fitzsimmons, J. Rokach
19883 citations
Semantic Scholar
The Lipoxins: Synthesis and Identification of the Natural Products
B. Fitzsimmons, J. Adams, Y. Leblanc, Y. Girard +2 more
19873 citations
Semantic Scholar
The lipoxins: synthesis and biosynthesis.
B. Fitzsimmons, Joshua Rokach
1988Advances in Experimental Medicine and Biology2 citations
Semantic Scholar
Dioxygenase and leukotriene A synthase activities of arachidonate 5- and 12-lipoxygenases purified from porcine leukocytes.
Shozo Yamamoto, Natsuo Ueda, C. Yokoyama, S. Kaneko +6 more
1987Advances in prostaglandin, thromboxane, and leukotriene research2 citations
Semantic Scholar
The lipoxins.
Joshua Rokach, B. Fitzsimmons
1988International Journal of Biochemistry1 citations
Semantic Scholar
Recent progress in the chemistry and biochemistry of lipoxygenase products: the lipoxins.
Joshua Rokach, B. Fitzsimmons, Y. Leblanc, Natsuo Ueda +1 more
1987Advances in prostaglandin, thromboxane, and leukotriene research1 citations
Semantic Scholar
The Leukotrienes: A Synthetic Chemist′s Perspective
J. Rokach, B. Fitzsimmons
19871 citations
Semantic Scholar
Trihydroxytetraene metabolites of arachidonic acid: the lipoxins.
J. Rokach, B. Fitzsimmons
1987Advances in prostaglandin, thromboxane, and leukotriene research1 citations
Semantic Scholar

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J. Rokach×22
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J. Rokach — researcher profile on SciRah
Y. Leblanc×19
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Y. Leblanc — researcher profile on SciRah
Joshua Rokach×10
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Joshua Rokach — researcher profile on SciRah
Jillian F. Evans×6
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Jillian F. Evans — researcher profile on SciRah

×6

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B. Fraser-Reid — researcher profile on SciRah

Julian Adams×5

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Julian Adams — researcher profile on SciRah

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A. Brash — researcher profile on SciRah

S. Charleson×5

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S. Charleson — researcher profile on SciRah

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Natsuo Ueda — researcher profile on SciRah

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C. Yokoyama — researcher profile on SciRah

A. Ford-Hutchinson×4

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A. Ford-Hutchinson — researcher profile on SciRah

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A. Foster — researcher profile on SciRah