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Darl D. Flake · SciRah

Researcher profile · Semantic Scholar

Darl D. Flake

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Darl D. Flake — researcher profile on SciRah

h-index: 11
Works: 35
Citations: 1,667

Most-cited papers

Prognostic value of an RNA expression signature derived from cell cycle proliferation genes for recurrence and death from prostate cancer: A retrospective study in two cohorts
J. Cuzick, G. P. Swanson, G. Fisher, A. Brothman +16 more
2011The Lancet Oncology751 citations Open access
Semantic Scholar
Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer.
B. Hennessy, K. Timms, M. Carey, A. Gutin +15 more
2010Journal of Clinical Oncology386 citations Open access
Semantic Scholar
Clinical validation of a gene expression signature that differentiates benign nevi from malignant melanoma
Loren E. Clarke, M. B. Warf, Darl D. Flake, A. Hartman +14 more
2015Journal of cutaneous pathology157 citations Open access
Semantic Scholar
BRCA1/2 mutations and expression: response to platinum chemotherapy in patients with advanced stage epithelial ovarian cancer.
Rebecca Byler Dann, J. Deloia, K. Timms, K. Zorn +4 more
2012Gynecologic Oncology115 citations
Semantic Scholar
Diagnostic Distinction of Malignant Melanoma and Benign Nevi by a Gene Expression Signature and Correlation to Clinical Outcomes
J. Ko, B. Matharoo-Ball, S. Billings, B. Thomson +15 more
2017Cancer Epidemiology, Biomarkers and Prevention72 citations Open access
Semantic Scholar
Analytical validation of a melanoma diagnostic gene signature using formalin-fixed paraffin-embedded melanocytic lesions.
M. B. Warf, Darl D. Flake, D. Adams, A. Gutin +3 more
2015Biomarkers in Medicine25 citations
Semantic Scholar
The clinical cell-cycle risk (CCR) score is associated with metastasis after radiation therapy and provides guidance on when to forgo combined androgen deprivation therapy with dose-escalated radiation.
J. Tward, L. Lenz, Darl D. Flake, S. Rajamani +20 more
2021International Journal of Radiation Oncology, Biology, Physics24 citations Open access
Semantic Scholar
Correlation of melanoma gene expression score with clinical outcomes on a series of melanocytic lesions.
J. Ko, Loren E. Clarke, Eugen C. Minca, K. Brown +2 more
2019Human Pathology24 citations Open access
Semantic Scholar
Evaluation of the 12-Gene Molecular Score and the 21-Gene Recurrence Score as Predictors of Response to Neo-adjuvant Chemotherapy in Estrogen Receptor-Positive, HER2-Negative Breast Cancer
H. Soliman, S. Wagner, Darl D. Flake, M. Robson +8 more
2020Annals of Surgical Oncology22 citations Open access
Semantic Scholar
Adjustment of the multi-biomarker disease activity score to account for age, sex and adiposity in patients with rheumatoid arthritis
J. Curtis, Darl D. Flake, M. Weinblatt, N. Shadick +14 more
2018Rheumatology20 citations Open access
Semantic Scholar
Personalizing Localized Prostate Cancer: Validation of a Combined Clinical Cell-cycle Risk (CCR) Score Threshold for Prognosticating Benefit From Multimodality Therapy.
J. Tward, T. Schlomm, S. Bardot, Daniel J. Canter +8 more
2021Clinical Genitourinary Cancer19 citations Open access
Semantic Scholar
Predicting Expected Absolute Chemotherapy Treatment Benefit in Women With Early-Stage Breast Cancer Using EndoPredict, an Integrated 12-Gene Clinicomolecular Assay
H. Soliman, Darl D. Flake, A. Magliocco, M. Robson +9 more
2019JCO Precision Oncology11 citations Open access
Semantic Scholar
Development and validation of a cell cycle progression signature for decentralized testing of men with prostate cancer.
Vanessa Kuhl, W. Clegg, Stephanie Meek, L. Lenz +18 more
2022Biomarkers in Medicine10 citations Open access
Semantic Scholar
Evaluation of the impact of age and adiposity on a multi-biomarker disease activity score before and after adjustment
J. Baker, J. Curtis, D. Chernoff, Darl D. Flake +4 more
2020Clinical Rheumatology7 citations Open access
Semantic Scholar
Prognostic capabilities and clinical utility of cell cycle progression testing, prostate imaging reporting and data system, version 2, and clinicopathologic data in management of localized prostate cancer.
David S. Morris, J. Woods, Byard Edwards, L. Lenz +6 more
2020Urologic oncology6 citations Open access
Semantic Scholar
Validation of the cell cycle progression score to differentiate indolent from aggressive prostate cancer in men diagnosed through transurethral resection of the prostate biopsy
J. Cuzick, S. Stone, L. Lenz, Darl D. Flake +5 more
2021Cancer Reports5 citations Open access
Semantic Scholar
External validation of a multi-biomarker-based score for predicting risk of cardiovascular disease in patients with rheumatoid arthritis
E. Sasso, B. Mabey, Darl D. Flake, E. Hitraya +5 more
2024PLoS ONE2 citations Open access
Semantic Scholar
Predicting expected absolute chemotherapy treatment benefit in women with early-stage breast cancer using a 12-gene expression assay.
W. Gradishar, M. Robson, Darl D. Flake, L. Schwartzberg +8 more
20182 citations
Semantic Scholar
Abstract P3-07-02: Prognostic and predictive relevance of HER2 status in ductal carcinomain situ: Results from the UK/ANZ DCIS trial
M. Thorat, S. Wagner, L. Jones, P. Levey +9 more
20162 citations
Semantic Scholar
Hereditary cancer risk assessment and genetic testing in the community urology practice setting
N. Shore, L. Lenz, Elizabeth S. Cogan, D. Iliev +16 more
2022The Prostate1 citations
Semantic Scholar
Hereditary cancer risk assessment in the community urology practice setting.
N. Shore, L. Lenz, Darl D. Flake, Stephanie Meek +10 more
2022Journal of Clinical Oncology1 citations
Semantic Scholar
FRI0553 DEVELOPMENT AND VALIDATION OF A BIOMARKER-BASED CARDIOVASCULAR RISK PREDICTION SCORE IN RHEUMATOID ARTHRITIS
J. Curtis, F. Xie, C. Crowson, B. Mabey +8 more
2020Annals of the Rheumatic Diseases1 citations
Semantic Scholar
In silico evaluation of the 12-gene molecular score (EndoPredict) and the recurrence score (Oncotype DX) as predictors of response to neo-adjuvant chemotherapy in estrogen receptor positive (ER+), HER2 negative (HER2-) breast cancer.
H. Soliman, M. Robson, S. Wagner, Darl D. Flake +8 more
20181 citations
Semantic Scholar
Laboratory bioassays and field-cage trials of Metarhizium spp. isolates with field-collected Mormon crickets (Anabrus simplex)
C. Keyser, É. K. K. Fernandes, D. Rangel, R. Foster +7 more
2017BioControl (Dordrecht)1 citations
Semantic Scholar
Abstract P1-09-06: Prognostic and predictive relevance of cell cycle progression (CCP) score in ductal carcinoma in situ: Results from the UK/ANZ DCIS trial
M. Thorat, S. Wagner, L. Jones, P. Levey +9 more
20171 citations
Semantic Scholar
Abstract P5-13-09: Identifying homologous recombination deficiency in breast cancer: Genomic instability score thresholds differ in breast cancer subtypes
K. Timms, L. Lenz, C. Neff, C. Solimeno +9 more
2022Cancer Research0 citations
Semantic Scholar
POS0456 EXTERNAL VALIDATION OF A MULTI-BIOMARKER-BASED CARDIOVASCULAR DISEASE RISK PREDICTION SCORE FOR RHEUMATOID ARTHRITIS PATIENTS
J. Curtis, E. Sasso, E. Hitraya, C. Chin +6 more
2021Annals of the Rheumatic Diseases0 citations
Semantic Scholar
AB1239 THE EFFECT OF INFLUENZA VACCINATION ON THE MULTI-BIOMARKER DISEASE ACTIVITY SCORE AND ITS COMPONENT BIOMARKERS IN HEALTHY SUBJECTS
D. Furst, L. Lenz, M. Horton, Darl D. Flake +2 more
20200 citations
Semantic Scholar
FRI0057 A MODEL FOR QUANTIFYING THE EFFECT OF INFLAMMATION ON CARDIOVASCULAR DISEASE RISK PREDICTION IN RA PATIENTS
R. Ben-Shachar, Darl D. Flake, R. Bamford, B. Mabey +2 more
2020Annals of the Rheumatic Diseases0 citations Open access
Semantic Scholar
AB0289 PREDICTION OF CARDIOVASCULAR EVENTS IN RHEUMATOID ARTHRITIS PATIENTS USING PROTEIN BIOMARKERS AND CLINICAL FACTORS
J. Curtis, F. Xie, Lang Chen, E. Sasso +6 more
2019Abstracts Accepted for Publication0 citations Open access
Semantic Scholar
THU0065 VALIDATION OF THE ADJUSTED MULTI-BIOMARKER DISEASE ACTIVITY SCORE FOR PREDICTING RISK OF RADIOGRAPHIC PROGRESSION FOR PATIENTS WITH RHEUMATOID ARTHRITIS
J. Curtis, M. Weinblatt, N. Shadick, C. H. Brahe +8 more
2019Poster Presentations0 citations Open access
Semantic Scholar
Evaluation of microarrays for measuring cell cycle progression (CCP) gene expression.
S. Stone, M. Cooperberg, Darl D. Flake, John W. Davis +3 more
20170 citations
Semantic Scholar
Abstract P4-11-15: Risk stratification within luminal B breast cancer using a second generation prognostic RNA signature
G. Pruneri, V. Bagnardi, D. Disalvatore, G. Curigliano +9 more
20150 citations
Semantic Scholar
Predicting chemotherapy response in invasive breast cancer.
D. Harrison, E. Rakha, A. Green, I. Kunkler +6 more
20140 citations
Semantic Scholar
Development of a Multi-Gene RNA Expression Signature that Differentiates Malignant and Benign Melanocytic Lesions
R. Acosta, R. Isa-Isa, Mariel Isa, R. Arenas +19 more
0 citations
Semantic Scholar

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