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S. Scilabra · SciRah

Researcher profile · Semantic Scholar

S. Scilabra

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S. Scilabra — researcher profile on SciRah

h-index: 16
Works: 61
Citations: 946

Most-cited papers

Functions of ‘A disintegrin and metalloproteases (ADAMs)’ in the mammalian nervous system
Hung-En Hsia, Johanna Tüshaus, Tobias Brummer, Yuanpeng Zheng +2 more
2019Cellular and Molecular Life Sciences114 citations Open access
Semantic Scholar
Strategies to Target ADAM17 in Disease: From Its Discovery to the iRhom Revolution
M. Calligaris, Doretta Cuffaro, S. Bonelli, D. Spanò +3 more
2021Molecules108 citations Open access
Semantic Scholar
LRP‐1‐mediated endocytosis regulates extracellular activity of ADAMTS‐5 in articular cartilage
Kazuhiro Yamamoto, L. Troeberg, S. Scilabra, Michele Pelosi +3 more
2013The FASEB Journal107 citations Open access
Semantic Scholar
Differential Regulation of Extracellular Tissue Inhibitor of Metalloproteinases-3 Levels by Cell Membrane-bound and Shed Low Density Lipoprotein Receptor-related Protein 1
S. Scilabra, L. Troeberg, Kazuhiro Yamamoto, H. Emonard +4 more
2012Journal of Biological Chemistry75 citations Open access
Semantic Scholar
The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3
L. Troeberg, Kazunari Fushimi, S. Scilabra, H. Nakamura +4 more
2009Matrix Biology65 citations Open access
Semantic Scholar
Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4)
Kazuhiro Yamamoto, K. Owen, A. Parker, S. Scilabra +4 more
2014Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Novel insights into the multifaceted and tissue-specific roles of the endocytic receptor LRP1
Kazuhiro Yamamoto, S. Scilabra, S. Bonelli, Anders Jensen +3 more
2024Journal of Biological Chemistry40 citations Open access
Semantic Scholar
TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1
A. Carreca, V. Pravata, Matthew Markham, S. Bonelli +4 more
2019Scientific Reports35 citations Open access
Semantic Scholar
Proof-of-Concept Study on the Use of Tangerine-Derived Nanovesicles as siRNA Delivery Vehicles toward Colorectal Cancer Cell Line SW480
Nima Rabienezhad Ganji, Ornella Urzì, Vincenza Tinnirello, Elisa Costanzo +13 more
2023International Journal of Molecular Sciences34 citations Open access
Semantic Scholar
Proteomic Substrate Identification for Membrane Proteases in the Brain
Stephan A. Müller, S. Scilabra, S. Lichtenthaler
2016Frontiers in Molecular Neuroscience32 citations Open access
Semantic Scholar
Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue.
S. Scilabra, Kazuhiro Yamamoto, Martina Pigoni, Kazuma Sakamoto +6 more
2017Matrix Biology27 citations Open access
Semantic Scholar
Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor
S. Scilabra, Martina Pigoni, V. Pravata, Tobias Schätzl +3 more
2018Scientific Reports26 citations Open access
Semantic Scholar
Proteomic analysis and functional validation reveal distinct therapeutic capabilities related to priming of mesenchymal stromal/stem cells with IFN-γ and hypoxia: potential implications for their clinical use
M. Calligaris, G. Zito, R. Busà, M. Bulati +13 more
2024Frontiers in Cell and Developmental Biology23 citations Open access
Semantic Scholar
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage.
Kazuhiro Yamamoto, C. Scavenius, Maria M. Meschis, Abdulrahman M E Gremida +10 more
2022Matrix Biology22 citations Open access
Semantic Scholar
GMP-compliant, serum-free cultures preserve therapeutic potential of extracellular vesicles from human mesenchymal stromal cells
Filippo Calascibetta, Annalisa Martorana, Margot Lo Pinto, C. Carcione +9 more
2025Frontiers in Cell and Developmental Biology19 citations Open access
Semantic Scholar
The Repertoire of Tissue Inhibitors of Metalloproteases: Evolution, Regulation of Extracellular Matrix Proteolysis, Engineering and Therapeutic Challenges
S. Costa, M. Ragusa, Gabriele Lo Buglio, S. Scilabra +1 more
2022Life18 citations Open access
Semantic Scholar
Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage
C.-Y. Yang, A. Chanalaris, S. Bonelli, O. McClurg +10 more
2020Osteoarthritis and Cartilage Open13 citations Open access
Semantic Scholar
Enhancing therapeutic efficacy through degradation of endogenous extracellular matrix in primary breast tumor spheroids
Alessandra Lo Cicero, S. Campora, Gabriele Lo Buglio, Paolo Cinà +3 more
2025The FEBS Journal12 citations Open access
Semantic Scholar
Investigating the Differential Circulating microRNA Expression in Adolescent Females with Severe Idiopathic Scoliosis: A Proof-of-Concept Observational Clinical Study
L. Raimondi, A. De Luca, A. Gallo, F. Perna +8 more
2024International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Tissue Inhibitor of Metalloproteases 3 (TIMP-3): In Vivo Analysis Underpins Its Role as a Master Regulator of Ectodomain Shedding
D. P. Spanò, S. Scilabra
2022Membranes11 citations Open access
Semantic Scholar
Topical application of a hyaluronic acid-based hydrogel integrated with secretome of human mesenchymal stromal cells for diabetic ulcer repair
F. Palumbo, M. Calligaris, L. Calzà, C. Fiorica +10 more
2024Regenerative Therapy9 citations
Semantic Scholar
High-resolution proteomics and machine-learning identify protein classifiers of honey made by Sicilian black honeybees (Apis mellifera ssp. sicula).
Giulia Biundo, M. Calligaris, Margot Lo Pinto, Danilo D’Apolito +5 more
2024Food Research International9 citations Open access
Semantic Scholar
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I
M. Calligaris, D. P. Spanò, S. Bonelli, Stephan A. Müller +11 more
2024Cellular and Molecular Life Sciences7 citations Open access
Semantic Scholar
Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates
A. Carreca, V. Pravata, Danilo D’Apolito, S. Bonelli +5 more
2021International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Effect of Hydrothermal Coatings of Magnesium AZ31 Alloy on Osteogenic Differentiation of hMSCs: From Gene to Protein Analysis
V. Costa, L. Raimondi, S. Scilabra, Margot Lo Pinto +9 more
2025Materials6 citations Open access
Semantic Scholar
An In Vitro Model of Glioma Development
G. Schiera, P. Cancemi, C. Di Liegro, F. Naselli +11 more
2023Genes6 citations Open access
Semantic Scholar
Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State
Chun-Yao Yang, S. Bonelli, M. Calligaris, A. Carreca +4 more
2022Membranes6 citations Open access
Semantic Scholar
High-Resolution Secretome Analysis of Chemical Hypoxia Treated Cells Identifies Putative Biomarkers of Chondrosarcoma
D. Spanò, S. Bonelli, M. Calligaris, A. Carreca +5 more
2022Proteomes6 citations Open access
Semantic Scholar
A vascularized three-dimensional model integrating primary breast tumor cells and microvascular fragments: mimicking the tumor microenvironment involved in chemoresistance
Alessandra Lo Cicero, Francesco La Monica, Gabriele Lo Buglio, S. Campora +6 more
2026Cancer Cell International5 citations Open access
Semantic Scholar
Clusterin Promotes the Migration and Invasion of Highly Aggressive Breast Cancer Cells Through Molecular Mechanisms That Affect the Cell Cytoskeleton and Extracellular Matrix Dynamics
Alessia Ciringione, Marina Marozzi, Silvana Belletti, Margot Lo Pinto +3 more
2026International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics
M. Calligaris, Chunchun Yang, S. Bonelli, D. Spanò +4 more
2023Frontiers in Molecular Biosciences5 citations Open access
Semantic Scholar
Proteome Profiling of Cerebrospinal Fluid and Machine Learning Reveal Protein Classifiers of Two Forms of Alzheimer’s Disease Characterized by Increased or Not Altered Levels of Tau
Elisabetta Scalia, M. Calligaris, Margot Lo Pinto, Salvatore Castelbuono +6 more
2025Molecular & Cellular Proteomics4 citations Open access
Semantic Scholar
Proteomic Characterization of Ubiquitin Carboxyl-Terminal Hydrolase 19 Deficient Cells Reveals a Role for USP19 in the Secretion of Lysosomal Proteins
S. Bonelli, Margot Lo Pinto, Yihong Ye, Stephan A. Müller +2 more
2024Molecular & Cellular Proteomics4 citations Open access
Semantic Scholar
Quantitative Mass Spectrometry-Based Secretome Analysis as a Tool to Investigate Metalloprotease and TIMP Activity.
Chun-Yao Yang, L. Troeberg, S. Scilabra
2020Methods in molecular biology4 citations
Semantic Scholar
Mesenchymal stem cell secretome discovery in response to a brushite-coated titanium alloy: highlighted a specific signature of factors involved in bone healing.
L. Raimondi, V. Costa, Gianluca Zappini, M. Piccinini +7 more
2025Biomaterials Advances3 citations Open access
Semantic Scholar
Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation
M. Pasqua, M. Barbuto, M. Calligaris, R. Di Gesù +6 more
2025Advanced Healthcare Materials3 citations Open access
Semantic Scholar
Uncovering the ligandome of low-density lipoprotein receptor-related protein 1 in cartilage: a top-down approach to identify therapeutic targets
Kazuhiro Yamamoto, C. Scavenius, Maria M. Meschis, E. H. Mogensen +9 more
2022bioRxiv3 citations Open access
Semantic Scholar
iRhom2 regulates HMGB1 secretion to modulate inflammation and hepatocyte senescence in an in vitro model of ischemia-reperfusion injury
M. Calligaris, R. Perriera, C. Carcione, V. Miceli +10 more
2026Cell Death and Disease2 citations
Semantic Scholar
Rapid prototyping of a multicompartment liver-on-chip for dynamic administration of tumour derived vesicles within an electrospun scaffold.
M. Testa, Marco Loria, F. Lopresti, C. Di Marco +8 more
2025Lab on a Chip2 citations
Semantic Scholar
Normothermic Machine Perfusion and Inflammatory Mediators Adsorption: First Kidney Transplant Experience
Duilo Pagano, R. Busà, Margot Lo Pinto, Agita Jukna +12 more
2025ASAIO journal (1992)2 citations
Semantic Scholar
Priming-Dependent Modulation of Secretome in Placenta- and Adipose-Derived Mesenchymal Stromal/Stem Cells: Toward Cell-Free Immunoregenerative Therapies for Osteochondral and Degenerative Joint Diseases
M. E. Ligotti, Elisabetta Scalia, S. Scilabra, Margot Lo Pinto +16 more
2026Stem Cell Reviews and Reports1 citations Open access
Semantic Scholar
Functional assessment of Streptomyces coelicolor secretome proteins associated with biogenic silver nanoparticles exhibiting multiple bioactive effects.
T. Faddetta, M. Calligaris, Valentina Catania, Elena Piacenza +14 more
2025International Journal of Biological Macromolecules1 citations Open access
Semantic Scholar
Human Amniotic MSC Response in LPS-Stimulated Ascites from Patients with Cirrhosis: FOXO1 Gene and Th17 Activation in Enhanced Antibacterial Activation
M. Pampalone, N. Cuscino, G. Iannolo, G. Amico +8 more
2024International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
Editorial: ADAM, ADAMTS and Astacin Proteases: Challenges and Breakthroughs in the -Omics Era
Kazuhiro Yamamoto, R. de Groot, S. Scilabra, H. Kwok +1 more
2021Frontiers in Molecular Biosciences1 citations Open access
Semantic Scholar
The Proteomic Profiling of a Platelet-Enriched Fraction Identifies an Inflammatory and Immune-Related Signature Associated with Non-Response to Treatment with Plasma Rich in Growth Factors in Knee Osteoarthritis
A. Colombini, Vincenzo Raffo, E. De Vecchi, Laura Pandolfi +6 more
2026Biomolecules0 citations Open access
Semantic Scholar
A Multi-Omics Approach Reveals Interleukin 1 Beta Priming as a Key Driver of Immunomodulatory and Regenerative Programs in Adipose-Derived Stem Cells for Osteoarthritis Therapy
V. Miceli, M. E. Ligotti, Vincenzo Raffo, S. Lopa +11 more
2026Cells0 citations Open access
Semantic Scholar
Extracellular Vesicles from Human Induced Pluripotent Stem Cells Reduce Lung Ischemia-Reperfusion Injury via Cytoprotective Mechanisms in both 2D Cultures and a Human Airway Organoid Model
R. Tinnirello, Maria Chiara Iachini, M. Cimino, Noemi Elia +19 more
2026International Journal on Biological Sciences0 citations Open access
Semantic Scholar
Computational identification of antifibrotic microRNAs targeting hepatic stellate cell activation
Nicolina Sciaraffa, Annalisa Martorana, A. Carreca, Filippo Calascibetta +10 more
2026Scientific Reports0 citations Open access
Semantic Scholar
Risk-based framework for GMP-compatible low-density platelet lysate-supplemented expansion of human cartilage cells for tissue repair
A. Colombini, S. Lopa, Vincenzo Raffo, Margot Lo Pinto +7 more
2026Journal of Translational Medicine0 citations Open access
Semantic Scholar
In vitro model of liver ischemia/reperfusion injury identifies iRhom2 as a novel disease target
R. Perriera, M. Calligaris, C. Carcione, R. Busa +6 more
2025Digestive and Liver Disease0 citations
Semantic Scholar

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