Researcher profile · Semantic Scholar

M. Fruciano

h-index: 16
Works: 30
Citations: 1,059

Most-cited papers

Effect of pirfenidone on proliferation, TGF-β-induced myofibroblast differentiation and fibrogenic activity of primary human lung fibroblasts.
Enrico Conte, E. Gili, E. Fagone, M. Fruciano +2 more
2014European Journal of Pharmaceutical Sciences350 citations
Semantic Scholar
Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms
Enrico Conte, M. Fruciano, E. Fagone, E. Gili +4 more
2011PLoS ONE155 citations Open access
Semantic Scholar
PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition
Enrico Conte, E. Gili, M. Fruciano, M. Korfei +7 more
2013Laboratory Investigation99 citations Open access
Semantic Scholar
Protective effect of orally administered carnosine on bleomycin-induced lung injury.
S. Cuzzocrea, T. Genovese, M. Failla, G. Vecchio +8 more
2007American Journal of Physiology - Lung cellular and Molecular Physiology69 citations
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Resveratrol inhibits transforming growth factor-β–induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt inhibition and PTEN restoration
E. Fagone, Enrico Conte, E. Gili, M. Fruciano +5 more
2011Experimental Lung Research54 citations Open access
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Anti-inflammatory and antifibrotic effects of resveratrol in the lung.
Enrico Conte, E. Fagone, M. Fruciano, E. Gili +2 more
2015Histology and Histopathology45 citations
Semantic Scholar
16,16-Dimethyl prostaglandin E2 efficacy on prevention and protection from bleomycin-induced lung injury and fibrosis.
M. Failla, T. Genovese, E. Mazzon, M. Fruciano +8 more
2009American Journal of Respiratory Cell and Molecular Biology40 citations Open access
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Thymosin β4 protects C57BL/6 mice from bleomycin‐induced damage in the lung
Enrico Conte, T. Genovese, E. Gili, E. Esposito +7 more
2013European Journal of Clinical Investigation35 citations
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Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice.
Enrico Conte, M. Iemmolo, E. Fagone, E. Gili +5 more
2014Immunobiology27 citations
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Circulating Coding and Long Non-Coding RNAs as Potential Biomarkers of Idiopathic Pulmonary Fibrosis
S. Di Mauro, A. Scamporrino, M. Fruciano, A. Filippello +12 more
2020International Journal of Molecular Sciences26 citations Open access
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Astrocytes Modify Migration of PBMCs Induced by β-Amyloid in a Blood-Brain Barrier in vitro Model
S. Spampinato, S. Merlo, E. Fagone, M. Fruciano +7 more
2019Frontiers in Cellular Neuroscience23 citations Open access
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Nailfold Videocapillaroscopy Is a Useful Tool to Recognize Definite Forms of Systemic Sclerosis and Idiopathic Inflammatory Myositis in Interstitial Lung Disease Patients
D. Sambataro, G. Sambataro, Alessandro Libra, Giovanna Vignigni +7 more
2020Diagnostics22 citations Open access
Semantic Scholar
Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid
S. Spampinato, S. Merlo, E. Fagone, M. Fruciano +3 more
2020Frontiers in Molecular Neuroscience22 citations Open access
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Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis
Enrico Conte, E. Fagone, E. Gili, M. Fruciano +6 more
2016OncoTarget17 citations Open access
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Protective effects of thymosin β4 in a mouse model of lung fibrosis
Enrico Conte, T. Genovese, E. Gili, E. Esposito +7 more
2012Annals of the New York Academy of Sciences17 citations
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Effects of thymosin β4 and its N-terminal fragment Ac-SDKP on TGF-β-treated human lung fibroblasts and in the mouse model of bleomycin-induced lung fibrosis
Enrico Conte, M. Iemmolo, M. Fruciano, E. Fagone +5 more
2015Expert Opinion on Biological Therapy16 citations
Semantic Scholar
Melatonin Enhances Neural Differentiation of Adipose-Derived Mesenchymal Stem Cells
I. R. Romano, Floriana D'Angeli, E. Gili, M. Fruciano +9 more
2024International Journal of Molecular Sciences12 citations Open access
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Pharmacological treatment in Idiopathic Pulmonary Fibrosis: current issues and future perspectives
E. Sciacca, G. Muscato, L. Spicuzza, M. Fruciano +5 more
2024Multidisciplinary Respiratory Medicine9 citations Open access
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Clinical and Prognostic Significance of p-ANCA Positivity in Idiopathic Pulmonary Fibrosis: A Retrospective Observational Study
Alessandro Libra, G. Muscato, G. Ielo, L. Spicuzza +6 more
2023Diagnostics9 citations Open access
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Developing PI3K Inhibitors for Respiratory Diseases.
E. Fagone, M. Fruciano, E. Gili, G. Sambataro +1 more
2022Current Topics in Microbiology and Immunology4 citations
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Molecular mechanisms of pirfenidone activity in human lung fibroblasts
Enrico Conte, M. Fruciano, E. Gili, E. Fagone +2 more
2014European Respiratory Journal4 citations
Semantic Scholar
Human lung fibroblasts increase CD4(+)CD25(+)Foxp3(+) T cells in co-cultured CD4(+) lymphocytes.
Enrico Conte, E. Gili, M. Fruciano, E. Fagone +1 more
2013Cellular Immunology3 citations
Semantic Scholar
Nintedanib for progressive pulmonary fibrosis in real-world setting: an observational study comparing outcomes with an IPF cohort
G. Muscato, Alessandro Libra, C. Reina, E. Gili +6 more
2026BMC Pulmonary Medicine2 citations Open access
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Exploring pathogenetic mechanisms in subglottic stenosis: A narrative review toward an integrated molecular classification
Serafina Martella, G. Cusumano, Giusi Bondì, L. La Via +4 more
2026Multidisciplinary Respiratory Medicine0 citations Open access
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Interstitial Lung Disease Secondary to Sjogren’s Syndrome and Antisynthetase Syndrome: Converging Disease Trajectories
G. Muscato, Giulia Morina, E. Fagone, M. Fruciano +6 more
2025Medicina0 citations
Semantic Scholar
Expression of the MET receptor kinase is a potential functional marker of Idiopathic pulmonary fibrosis
G. Stella, E. Gili, E. Fagone, M. Milan +4 more
20170 citations
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PI3K p110γ is overexpressed in IPF lung tissue and fibroblast cells. In vitro effects of its inhibition
Enrico Conte, E. Gili, M. Fruciano, M. Korfei +7 more
20120 citations
Semantic Scholar
Lung injury and repair : reactive oxygen species and beyond
M. Takata, Jeroen Tibboel, S. Joza, I. Reiss +9 more
20120 citations
Semantic Scholar
Role of phosphatidylinositol-3-kinase (PI3K) in TGF-β-induced proliferation and differentiation of human lung fibroblasts into myofibroblasts
Enrico Conte, M. Fruciano, E. Fagone, E. Gili +3 more
2011European Respiratory Journal0 citations
Semantic Scholar
Protective Effect of Resveratrol on TGF-β-Induced Lung Fibroblast Differentiation.
C. Vancheri, E. Fagone, C. Crimi, M. Fruciano +6 more
2009Asian Test Symposium0 citations
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M. Iemmolo

×13

N. Crimi×11

T. Genovese×6

G. Muscato×5