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S. Jacobus · SciRah

Researcher profile · Semantic Scholar

S. Jacobus

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S. Jacobus — researcher profile on SciRah

h-index: 27
Works: 72
Citations: 3,940

Most-cited papers

Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial
S. Rajkumar, S. Jacobus, N. Callander, R. Fonseca +6 more
2009The Lancet Oncology946 citations Open access
Semantic Scholar
Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma
P. Richardson, S. Jacobus, E. Weller, H. Hassoun +52 more
2022New England Journal of Medicine392 citations Open access
Semantic Scholar
Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib
N. Wagle, B. Grabiner, E. V. Van Allen, Eran Hodis +18 more
2014Cancer Discovery284 citations Open access
Semantic Scholar
Neoadjuvant dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin with pegfilgrastim support in muscle-invasive urothelial cancer: pathologic, radiologic, and biomarker correlates.
T. Choueiri, S. Jacobus, J. Bellmunt, Angela Q. Qu +15 more
2014Journal of Clinical Oncology261 citations Open access
Semantic Scholar
Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma.
S. Lonial, S. Jacobus, R. Fonseca, M. Weiss +13 more
2020Journal of Clinical Oncology227 citations Open access
Semantic Scholar
Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer.
T. Choueiri, R. Ross, S. Jacobus, U. Vaishampayan +16 more
2012Journal of Clinical Oncology174 citations Open access
Semantic Scholar
Phase III trial of lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone in newly diagnosed multiple myeloma (E4A03): A trial coordinated by the Eastern Cooperative Oncology Group
S. Rajkumar, S. Jacobus, N. Callander, R. Fonseca +5 more
2007146 citations
Semantic Scholar
Clinical significance of TP53 mutation in myeloma
W. Chng, T. Price-Troska, N. Gonzalez-Paz, S. V. Van Wier +8 more
2007Leukemia142 citations
Semantic Scholar
Prognostic factors for hyperdiploid-myeloma: effects of chromosome 13 deletions and IgH translocations
W. Chng, R. Santana-Davila, S. V. Van Wier, G. Ahmann +14 more
2006Leukemia134 citations Open access
Semantic Scholar
A Randomized Trial of Lenalidomide Plus High-Dose Dexamethasone (RD) Versus Lenalidomide Plus Low-Dose Dexamethasone (Rd) in Newly Diagnosed Multiple Myeloma (E4A03): A Trial Coordinated by the Eastern Cooperative Oncology Group.
S. Rajkumar, S. Jacobus, N. Callander, R. Fonseca +5 more
2006121 citations
Semantic Scholar
A phase 2 study of carboplatin plus docetaxel in men with metastatic hormone‐refractory prostate cancer who are refractory to docetaxel
R. Ross, T. Beer, S. Jacobus, G. Bubley +4 more
2008Cancer105 citations Open access
Semantic Scholar
Melphalan, prednisone, and thalidomide vs melphalan, prednisone, and lenalidomide (ECOG E1A06) in untreated multiple myeloma.
A. K. Stewart, S. Jacobus, R. Fonseca, M. Weiss +3 more
2015Blood88 citations Open access
Semantic Scholar
Disease and outcome disparities in multiple myeloma: exploring the role of race/ethnicity in the Cooperative Group clinical trials
S. Ailawadhi, S. Jacobus, R. Sexton, A. Stewart +8 more
2018Blood Cancer Journal80 citations Open access
Semantic Scholar
Randomized trial of lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone in newly diagnosed myeloma (E4A03), a trial coordinated by the Eastern Cooperative Oncology Group: Analysis of response, survival, and outcome wi
S. Rajkumar, S. Jacobus, N. Callander, R. Fonseca +6 more
200878 citations
Semantic Scholar
Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival
B. V. Van Ness, Christine Ramos, M. Haznadar, A. Hoering +17 more
2008BMC Medicine60 citations Open access
Semantic Scholar
Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone.
Shaji K. Kumar, H. Uno, S. Jacobus, S. V. Van Wier +8 more
2011Blood50 citations Open access
Semantic Scholar
Primary therapy with single agent bortezomib as induction, maintenance, and re-Induction in patients with high risk myeloma: results of the ECOG E2A02 trial
A. Dispenzieri, S. Jacobus, D. Vesole, N. Callandar +2 more
2010Leukemia49 citations Open access
Semantic Scholar
Phase II study of interleukin-12 for treatment of plateau phase multiple myeloma (E1A96): A trial of the Eastern Cooperative Oncology Group
M. Lacy, S. Jacobus, E. Blood, Neil E. Kay +2 more
2009Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis49 citations Open access
Semantic Scholar
Radium‐223 Use in Clinical Practice and Variables Associated With Completion of Therapy
R. McKay, S. Jacobus, M. Fiorillo, E. Ledet +5 more
2017Clinical Genitourinary Cancer48 citations
Semantic Scholar
Response to docetaxel/carboplatin‐based chemotherapy as first‐ and second‐line therapy in patients with metastatic hormone‐refractory prostate cancer
M. Nakabayashi, O. Sartor, S. Jacobus, M. M. Regan +5 more
2008BJU International45 citations
Semantic Scholar
The Prostate 68 : 1592 ^ 1598 ( 2008 ) Relationship Between SerumAdiponectin and ProstateCancerGrade
D. Sher, William K. Oh, S. Jacobus, Meredith M. Regan +2 more
200841 citations
Semantic Scholar
Elevated plasma tissue inhibitor of metalloproteinase‐1 levels predict decreased survival in castration‐resistant prostate cancer patients
William K. Oh, R. Vargas, S. Jacobus, K. Leitzel +8 more
2011Cancer39 citations Open access
Semantic Scholar
Outcome with Lenalidomide Plus Dexamethasone Followed by Early Autologous Stem Cell Transplantation In the ECOG E4A03 Randomized Clinical Trial
David Siegel, S. Jacobus, S. Rajkumar, R. Abonour +4 more
201039 citations
Semantic Scholar
Absence of relationship between steroid hormone levels and prostate cancer tumor grade.
D. Sher, C. Mantzoros, S. Jacobus, M. Regan +2 more
2009Urology39 citations
Semantic Scholar
Impact of high-risk classification by FISH: An Eastern Cooperative Oncology Group (ECOG) study E4A03
S. Jacobus, Shaji K. Kumar, H. Uno, S. V. Van Wier +8 more
2011British Journal of Haematology37 citations Open access
Semantic Scholar
The Impact of Common Genetic Variations in Genes of the Sex Hormone Metabolic Pathways on Steroid Hormone Levels and Prostate Cancer Aggressiveness
T. Sun, W. Oh, S. Jacobus, M. Regan +4 more
2011Cancer Prevention Research34 citations Open access
Semantic Scholar
Activity of ketoconazole after taxane‐based chemotherapy in castration‐resistant prostate cancer
M. Nakabayashi, William K. Oh, S. Jacobus, M. M. Regan +3 more
2009BJU International27 citations
Semantic Scholar
E3A06: Randomized phase III trial of lenalidomide versus observation alone in patients with asymptomatic high-risk smoldering multiple myeloma.
S. Lonial, S. Jacobus, M. Weiss, Shaji K. Kumar +11 more
2019Journal of Clinical Oncology21 citations
Semantic Scholar
Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in patients with newly diagnosed multiple myeloma on the ECOG-ACRIN E4A03 randomized clinical trial: long-term follow-up
N. Biran, S. Jacobus, D. Vesole, N. Callander +7 more
2016Blood Cancer Journal16 citations Open access
Semantic Scholar
OAB-052: Impact of chromosome 1 abnormalities on newly diagnosed multiple myeloma treated with proteasome inhibitor, immunomodulatory drug, and dexamethasone: analysis from the ENDURANCE ECOG-ACRIN E1A11 trial
P. Kapoor, T. Schmidt, S. Jacobus, Zi-Han Wei +5 more
2021Clinical Lymphoma, Myeloma & Leukemia15 citations
Semantic Scholar
E1A06: A phase III trial comparing melphalan, prednisone, and thalidomide (MPT) versus melphalan, prednisone, and lenalidomide (MPR) in newly diagnosed multiple myeloma (MM).
A. Stewart, S. Jacobus, R. Fonseca, M. Weiss +3 more
201414 citations
Semantic Scholar
Prognostic Significance of Increases in Hemoglobin in Renal Cell Carcinoma Patients During Treatment With VEGF‐directed Therapy
Abhishek Tripathi, S. Jacobus, H. Feldman, T. Choueiri +1 more
2017Clinical Genitourinary Cancer13 citations
Semantic Scholar
Phase 2 Study of Bevacizumab and Temsirolimus After VEGFR TKI in Metastatic Renal Cell Carcinoma.
K. Mahoney, S. Jacobus, R. Bhatt, Jia-Xi Song +10 more
2016Clinical Genitourinary Cancer13 citations Open access
Semantic Scholar
Lenalidomide Plus Low-Dose Dexamethasone (Ld): Superior One and Two Year Survival Regardless of Age Compared to Lenalidomide Plus High-Dose Dexamethasone (LD)
D. Vesole, S. Jacobus, S. Rajkumar, R. Abonour +5 more
201013 citations
Semantic Scholar
Capecitabine and oxaliplatin as first and second line treatment for locally advanced and metastatic pancreatic ductal adenocarcinoma.
A. Bullock, K. Stuart, S. Jacobus, T. Abrams +3 more
2017Journal of Gastrointestinal Oncology11 citations Open access
Semantic Scholar
Randomized phase III trial of consolidation therapy with bortezomib–lenalidomide–Dexamethasone (VRd) vs bortezomib–dexamethasone (Vd) for patients with multiple myeloma who have completed a dexamethasone based induction regimen
S. Jacobus, S. Rajkumar, M. Weiss, A. Stewart +5 more
2016Blood Cancer Journal11 citations Open access
Semantic Scholar
The Treatment of Multiple Myeloma Utilizing Vincristine, Carmustine (BCNU), Melphalan, Cyclophosphamide, and Prednisone (VBMCP) Alternating with High-Dose Cyclophosphamide and Alpha2 Beta-Interferon Versus VBMCP
R. Kyle, S. Jacobus, W. Friedenberg, Coenraad Frederik Slabber +2 more
2009Cancer10 citations Open access
Semantic Scholar
A phase II trial of abiraterone acetate without glucocorticoids for men with metastatic castration-resistant prostate cancer.
R. McKay, L. Werner, S. Jacobus, A. Jones +9 more
2018Cancer9 citations Open access
Semantic Scholar
A double-blind randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated advanced urothelial cancer.
T. Choueiri, U. Vaishampayan, Evan Y. Yu, D. Quinn +6 more
2011Journal of Clinical Oncology7 citations
Semantic Scholar
Development of the Functional Assessment of Cancer Therapy-Multiple Myeloma (FACT-MM) Scale and Validation in the Eastern Cooperative Oncology Group Trial E1A05,
M. Weiss, S. Jacobus, L. Wagner, D. Cella +3 more
20117 citations
Semantic Scholar
Evaluating a Video-Based, Personalized Webpage in Genitourinary Oncology Clinical Trials: A Phase 2 Randomized Trial
R. McKay, H. Mills, L. Werner, A. Choudhury +9 more
2018Journal of Medical Internet Research4 citations Open access
Semantic Scholar
Phase II Trial Of Initial Safety and Toxicity Prior To The Phase III Trial Of Lenalidomide Versus Observation Alone In Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma (E3A06): A Trial Coordinated By The Eastern Cooperative Oncology Group
S. Lonial, S. Jacobus, M. Weiss, R. Fonseca +2 more
20124 citations
Semantic Scholar
ECOG-ACRIN EAA172: Phase 1/2 study of daratumumab, bortezomib, dexamethasone (DVd) with or without venetoclax in relapsed/refractory multiple myeloma (RRMM) with assessment for t(11;14) status.
Michael A. Thompson, S. Jacobus, Shaji K. Kumar, Murali Janakiram +4 more
2019Journal of Clinical Oncology3 citations
Semantic Scholar
Strategies to overcome barriers to accrual (BtA) to NCI-sponsored clinical trials: A project of the NCI-Myeloma Steering Committee Accrual Working Group (NCI-MYSC AWG).
M. Weiss, M. Gertz, R. Little, V. Rajkumar +15 more
20133 citations
Semantic Scholar
Phase II study of neoadjuvant dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) chemotherapy in patients with muscle-invasive urothelial cancer (MI-UC): Pathologic and radiologic response, serum tumor markers, and DNA excision repair pathway biomarkers in relation to disease-
Angela Q. Qu, S. Jacobus, S. Signoretti, E. Stack +3 more
20133 citations
Semantic Scholar
Identification of Significant Barriers to Accrual (BtA) to NCI Sponsored Multiple Myeloma – Clinical Trials (MM-CT): A Step towards Improving Accrual to Clinical Trials.
M. Weiss, S. Jacobus, R. Abonour, K. Anderson +16 more
20123 citations
Semantic Scholar
Renal Function Measures Improve on Lenalidomide and Dexamethasone and Compete with Patient Characteristics to Predict Lenalidomide Dose Density and Hematologic Toxicity: An E4A03 Analysis
R. Harvey, S. Jacobus, S. Rajkumar, P. Greipp +1 more
20113 citations
Semantic Scholar
Identification of a novel urothelial carcinoma (UC) biomarker of lethality.
J. Rosenberg, L. Werner, S. Selvarajah, B. Weir +16 more
2011Journal of Clinical Oncology3 citations
Semantic Scholar
Primary Therapy with Bortezomib—the Role of Induction, Maintenance, and Re-Induction in Patients with High Risk Myeloma. Update of Results from E2A02.
A. Dispenzieri, S. Jacobus, D. Vesole, S. Rajkumar +1 more
20083 citations
Semantic Scholar
Do β2 microglobulin levels affect survival of newly diagnosed myeloma patients with translocation t(4;14) or 17p13 deletion treated with conventional chemotherapy?
W. Chng, S. Jacobus, Rafael Fonseca
2008Leukemia3 citations Open access
Semantic Scholar

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