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J. Holcenberg · SciRah

Researcher profile · Semantic Scholar

J. Holcenberg

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J. Holcenberg — researcher profile on SciRah

h-index: 25
Works: 117
Citations: 3,570

Most-cited papers

Liposomal Amphotericin B for Empirical Therapy in Patients with Persistent Fever and Neutropenia
T. Walsh, R. Finberg, C. Arndt, J. Hiemenz +9 more
1999838 citations Open access
Semantic Scholar
A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis.
S. Goldman, J. Holcenberg, J. Finklestein, Raymond J. Hutchinson +6 more
2001Blood449 citations Open access
Semantic Scholar
Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group.
T. Walsh, R. Finberg, C. Arndt, J. Hiemenz +8 more
1999New England Journal of Medicine383 citations
Semantic Scholar
Isolation, crystallization, and properties of Achromobacteraceae glutaminase-asparaginase with antitumor activity.
Joseph Roberts, J. Holcenberg, William C. Dolowy
1972Journal of Biological Chemistry111 citations Open access
Semantic Scholar
Asparaginase Pharmacokinetics After Intensive Polyethylene Glycol-Conjugated L-Asparaginase Therapy for Children with Relapsed Acute Lymphoblastic Leukemia
D. Hawkins, Julie R. Park, B. Thomson, J. Felgenhauer +3 more
2004Clinical Cancer Research104 citations
Semantic Scholar
Phase I trial and pharmacokinetics of gemcitabine in children with advanced solid tumors.
J. Reid, Wenchun Qu, Stephanie L. Safgren, M. Ames +4 more
2004Journal of Clinical Oncology102 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of oral methotrexate and mercaptopurine in children with lower risk acute lymphoblastic leukemia: a joint children's cancer group and pediatric oncology branch study.
F. Balis, J. Holcenberg, D. Poplack, Jeff Ge +8 more
1998Blood100 citations
Semantic Scholar
Enzymes as drugs.
J. Holcenberg, J. Roberts
1977Annual Review of Pharmacology and Toxicology98 citations
Semantic Scholar
Phase I study of 2'-deoxycoformycin in acute lymphoblastic leukemia.
D. Poplack, S. Sallan, G. Rivera, J. Holcenberg +7 more
1981Cancer Research89 citations
Semantic Scholar
A phase I trial of solubilized DR2:MBP84-102 (AG284) in multiple sclerosis
Donald Eliot Goodkin, M. Shulman, J. Winkelhake, Emmanuelle Waubant +10 more
2000Neurology58 citations
Semantic Scholar
Phase I/II trial and pharmacokinetics of intrathecal diaziquone in refractory meningeal malignancies.
S. Berg, F. Balis, S. Zimm, R. F. Murphy +6 more
1992Journal of Clinical Oncology53 citations
Semantic Scholar
Phase I study of ICRF-187 using a daily for 3 days schedule.
D. V. Von Hoff, D. Howser, B. Lewis, J. Holcenberg +2 more
1981Cancer treatment reports49 citations
Semantic Scholar
A Pharmacoeconomic Analysis of Pegaspargase Versus Native Escherichia Coli l-Asparaginase for the Treatment of Children With Standard-Risk, Acute Lymphoblastic Leukemia: The Children's Cancer Group Study (CCG-1962)
Helen A Kurre, A. Ettinger, D. Veenstra, P. Gaynon +5 more
2002Journal of pediatric hematology/oncology43 citations
Semantic Scholar
Phase I study of topotecan administered as a 21-day continous infusion in children with recurrent solid tumors: a report from the Children's Cancer Group.
H. Frangoul, Matthew M. Ames, R. Mosher, J. Reid +6 more
1999Clinical Cancer Research42 citations
Semantic Scholar
Enzyme therapy: problems and solutions.
J. Holcenberg
1982Annual Review of Biochemistry41 citations
Semantic Scholar
Correlation between High Vascular Endothelial Growth Factor-A Serum Levels and Treatment Outcome in Patients with Standard-Risk Acute Lymphoblastic Leukemia: A Report from Children's Oncology Group Study CCG-1962
I. Avramis, E. Panosyan, F. Dorey, J. Holcenberg +1 more
2006Clinical Cancer Research40 citations Open access
Semantic Scholar
Randomized placebo‐controlled trial of granulocyte‐macrophage colony‐stimulating‐factor support for dose‐intensive cyclophosphamide, etoposide, and cisplatin
J. Yau, James A. Neldhart, P. Triozzi, S. Verma +6 more
1996American journal of hematology/oncology36 citations Open access
Semantic Scholar
Phase I study of ICRF-187 in pediatric cancer patients and comparison of its pharmacokinetics in children and adults.
J. Holcenberg, K. D. Tutsch, R. Earhart, R. Ungerleider +4 more
1986Cancer treatment reports34 citations
Semantic Scholar
The relative tolerance of children and adults to anticancer drugs.
D. Glaubiger, D. V. Von Hoff, J. Holcenberg, B. Kamen +2 more
1981Frontiers of radiation therapy and oncology32 citations
Semantic Scholar
Glutaminase induced prolonged regression of established Ehrlich carcinoma.
Joseph Roberts, J. Holcenberg, William C. Dolowy
1971Life sciences. Pt. 2: Biochemistry, general and molecular biology29 citations
Semantic Scholar
Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia
P. Cole, R. Drachtman, Angela K. Smith, S. Cate +5 more
2005Clinical Cancer Research26 citations Open access
Semantic Scholar
Human deoxycytidine kinase. Sequence of cDNA clones and analysis of expression in cell lines with and without enzyme activity.
Sheng-He Huang, J. Tomich, Huayang Wu, Ambrose Y. Jong +1 more
1989Journal of Biological Chemistry26 citations Open access
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Substitution of oral and intravenous thioguanine for mercaptopurine in a treatment regimen for children with standard risk acute lymphoblastic leukemia: A collaborative Children's Oncology Group/National Cancer Institute pilot trial (CCG‐1942)
Shana S. Jacobs, L. Stork, B. Bostrom, R. Hutchinson +8 more
2007Pediatric Blood & Cancer25 citations
Semantic Scholar
Pharmacodynamic and DNA methylation studies of high-dose 1-β-d-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia
V. Avramis, Robert A. Mecum, J. Nyce, D. A. Steele +1 more
2004Cancer Chemotherapy and Pharmacology25 citations
Semantic Scholar
Phase I Trial and Pharmacokinetic Study of Trimetrexate
F. Balis, R. Patel, E. Luks, K. Doherty +7 more
200624 citations
Semantic Scholar
Thyroid carcinoma following treatment for acute lymphoblastic leukemia
Thomas T. Tang, J. Holcenberg, S. Duck, Albertina E. Hodach +2 more
1980Cancer23 citations
Semantic Scholar
Physical properties of antitumor glutaminase-asparaginase from Pseudomonas 7A.
J. Holcenberg, D. Teller
1976Journal of Biological Chemistry22 citations
Semantic Scholar
Cystathionine metabolism in neuroblastoma
Catherine J. Klein, Brian Roberts, L. Glodé, J. Holcenberg
1988Cancer21 citations Open access
Semantic Scholar
Renal irradiation and the pharmacology and toxicity of methotrexate and cisplatinum.
J. Moulder, J. Holcenberg, B. Kamen, M. Cheng +1 more
1986International Journal of Radiation Oncology, Biology, Physics21 citations
Semantic Scholar
Physical properties of Acinetobacter glutaminase-asparaginase with antitumor activity.
J. Holcenberg, David C. Teller, Joseph Roberts, William C. Dolowy
1972Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse
B. Thomson, Julie R. Park, J. Felgenhauer, S. Meshinchi +6 more
2004Pediatric Blood & Cancer17 citations
Semantic Scholar
Phase I trial of mitoxantrone in children.
R. Ungerleider, C. Pratt, T. Vietti, J. Holcenberg +3 more
1985Cancer treatment reports14 citations
Semantic Scholar
Effect of hepatic irradiation on the toxicity and pharmacokinetics of adriamycin in children.
J. Holcenberg, Larry E. Kun, B. Ring, William E. Evans
1981International Journal of Radiation Oncology, Biology, Physics14 citations
Semantic Scholar
Nicotinic Acid Metabolism
J. Holcenberg, Lin Tsai
200312 citations Open access
Semantic Scholar
Effect of asparaginase on cell membranes of sensitive and resistants mouse lymphoma cells
E. Ankel, J. Zirneski, B. Ring, J. Holcenberg
1984In Vitro12 citations
Semantic Scholar
Aziridinylbenzoquinone (AZQ) treatment of central nervous system leukemia.
B. Kamen, J. Holcenberg, S. Siegel
1982Cancer treatment reports12 citations
Semantic Scholar
Effect of L-glutaminase on transformation and DNA synthesis of normal lymphocytes.
Robert Schrek, K. Batra, J. Holcenberg, Joseph Roberts +1 more
1972Acta Haematologica12 citations
Semantic Scholar
Treatment of rheumatoid arthritis with a DR4/1 peptide.
E. S. St Clair, S. Cohen, M. L. Lee, R. Fleischmann +9 more
2000Journal of Rheumatology11 citations
Semantic Scholar
Oral versus intravenous methotrexate: another opinion.
B. Kamen, N. Winick, J. Holcenberg
1998Journal of Clinical Oncology11 citations
Semantic Scholar
Phase I study of succinylated acinetobacter L-glutaminase-L-asparaginase.
J. Holcenberg, B. Camitta, Luis D. Borella, B. Ring
1979Cancer treatment reports10 citations
Semantic Scholar
Optimal asparaginase therapy.
J. Holcenberg
2004Journal of pediatric hematology/oncology9 citations
Semantic Scholar
Effect of total-body irradiation with bone marrow transplantation on toxicity of cisplatin.
J. Moulder, Brian Fish, J. Holcenberg, M. Cheng
1988NCI monographs : a publication of the National Cancer Institute9 citations
Semantic Scholar
Relationship of 5'-nucleotidase activity and antileukemic effect in 2'-deoxycoformycin therapy.
R. Wortmann, J. Holcenberg, D. Poplack
1982Cancer treatment reports8 citations
Semantic Scholar
Safety of delayed leucovorin "rescue" following high-dose methotrexate in children.
B. Camitta, J. Holcenberg
1978Medical and Pediatric Oncology8 citations
Semantic Scholar
High-dose trimetrexate and minimal-dose leucovorin: a case for selective protection?
Martina Hum, J. Holcenberg, Isabelle Tkaczewski, Jill W. Weaver +2 more
1998Clinical Cancer Research7 citations
Semantic Scholar
Effect of succinylated Acinetobacter glutaminase-asparaginase treatment on an acute myeloid leukemia in the rat (BNML).
P. Sonneveld, J. Holcenberg, D. V. van Bekkum
1979European Journal of Cancer7 citations
Semantic Scholar
Characterization of crystals of L-glutaminase-asparaginase from Acinetobacter glutaminasificans and Pseudomonas 7A.
Alexander Wlodawer, Joseph Roberts, J. Holcenberg
1977Journal of Molecular Biology7 citations
Semantic Scholar
New approaches to overcome drug resistance
V. Avramis, R. Biener, J. Holcenberg
19876 citations
Semantic Scholar
Treatment of refractory acute lymphoblastic leukemia with teniposide and cytarabine.
B. A. Kamen, J. Casper, S. Lauer, B. Camitta +1 more
1986Cancer treatment reports6 citations
Semantic Scholar
Sequential high-dose cytosine arabinoside and L-asparaginase in childhood leukemia in relapse.
L. Ettinger, R. Biener, J. Finklestein, P. Kamalakar +3 more
1985Seminars in Oncology6 citations
Semantic Scholar

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