I. Falková

Most-cited papers

1. Particles with similar LET values generate DNA breaks of different complexity and reparability: a high-resolution microscopy analysis of γH2AX/53BP1 foci.

   L. Jezková, M. Zadneprianetc, E. Kulikova, E. Smirnova +9 more

   2018Nanoscale66 citations Open access

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2. Two New Faces of Amifostine: Protector from DNA Damage in Normal Cells and Inhibitor of DNA Repair in Cancer Cells.

   M. Hofer, M. Falk, D. Komůrková, I. Falková +9 more

   2016Journal of Medicinal Chemistry60 citations Open access

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3. Challenges and Contradictions of Metal Nano-Particle Applications for Radio-Sensitivity Enhancement in Cancer Therapy

   E. Pagáčová, L. Štefančíková, Franz Schmidt-Kaler, G. Hildenbrand +12 more

   2019International Journal of Molecular Sciences44 citations Open access

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4. Loss of the p53 tumor suppressor activity is associated with negative prognosis of mantle cell lymphoma.

   L. Štefančíková, M. Moulis, P. Fabián, B. Ravčuková +6 more

   2010International Journal of Oncology44 citations Open access

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5. Theoretical and experimental study of the antifreeze protein AFP752, trehalose and dimethyl sulfoxide cryoprotection mechanism: correlation with cryopreserved cell viability.

   I. Kratochvílová, Martin Golan, Karel Pomeisl, J. Richter +10 more

   2017RSC Advances42 citations Open access

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6. Prognostic impact of p53 aberrations for R-CHOP-treated patients with diffuse large B-cell lymphoma.

   L. Štefančíková, M. Moulis, P. Fabián, I. Vášová +8 more

   2011International Journal of Oncology41 citations Open access

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7. Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization Microscopy

   E. Bobkova, Daniel Depeš, Jin-Ho Lee, L. Jezková +15 more

   2018International Journal of Molecular Sciences37 citations Open access

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8. Chromatin architecture changes and DNA replication fork collapse are critical features in cryopreserved cells that are differentially controlled by cryoprotectants

   M. Falk, I. Falková, O. Kopecna, Alena Bačı́ková +11 more

   2018Scientific Reports33 citations Open access

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9. Function of chromatin structure and dynamics in DNA damage, repair and misrepair: γ-rays and protons in action.

   L. Jezková, M. Falk, I. Falková, M. Davídková +8 more

   2014Applied Radiation and Isotopes30 citations

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10. Heterochromatinization associated with cell differentiation as a model to study DNA double strand break induction and repair in the context of higher-order chromatin structure.

    M. Falk, E. Lukášová, L. Štefančíková, E. Baranova +7 more

    2014Applied Radiation and Isotopes28 citations

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11. Determining Omics spatiotemporal dimensions using exciting new nanoscopy techniques to assess complex cell responses to DNA damage: part A--radiomics.

    M. Falk, M. Hausmann, E. Lukášová, Abin Biswas +15 more

    2014Critical Reviews in Eukaryotic Gene Expression24 citations

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12. Single-molecule localization microscopy as a promising tool for γH2AX/53BP1 foci exploration

    Daniel Depeš, Jin-Ho Lee, E. Bobkova, L. Jezková +13 more

    2018European Physical Journal D : Atomic, Molecular and Optical Physics23 citations

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13. Elucidation of the Clustered Nano-Architecture of Radiation-Induced DNA Damage Sites and Surrounding Chromatin in Cancer Cells: A Single Molecule Localization Microscopy Approach

    M. Hausmann, M. Falk, Charlotte Neitzel, A. Hofmann +5 more

    2021International Journal of Molecular Sciences19 citations Open access

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14. Changes in Cryopreserved Cell Nuclei Serve as Indicators of Processes during Freezing and Thawing.

    I. Kratochvílová, O. Kopecna, Alena Bačı́ková, E. Pagáčová +6 more

    2018Langmuir16 citations

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15. Determining Omics spatiotemporal dimensions using exciting new nanoscopy techniques to assess complex cell responses to DNA damage: part B--structuromics.

    M. Falk, M. Hausmann, E. Lukášová, Abin Biswas +15 more

    2014Critical Reviews in Eukaryotic Gene Expression16 citations

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16. Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells

    Lucie Dobešová, Theresa Gier, O. Kopecna, E. Pagáčová +10 more

    2022Pharmaceutics15 citations Open access

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17. Sequestration of MBNL1 in tissues of patients with myotonic dystrophy type 2.

    Zdeněk Lukáš, Martin Falk, Josef Feit, Ondřej Souček +6 more

    2012Neuromuscular Disorders15 citations

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18. In Vitro Comparison of Passive and Active Clinical Proton Beams

    A. Michaelidesová, J. Vachelová, Jana Klementová, T. Urban +7 more

    2020International Journal of Molecular Sciences13 citations Open access

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19. Single Molecule Localization Microscopy Analyses of DNA-Repair Foci and Clusters Detected Along Particle Damage Tracks

    M. Hausmann, Charlotte Neitzel, E. Bobkova, David Nagel +13 more

    2020Frontiers of Physics13 citations Open access

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20. Complex analysis of cyclin D1 expression in mantle cell lymphoma: two cyclin D1-negative cases detected

    L. Štefančíková, M. Moulis, P. Fabián, I. Falková +4 more

    2009Journal of Clinical Pathology9 citations

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21. An unusual p53 mutation detected in Burkitt's lymphoma: 30 bp duplication.

    J. Šmardová, D. Grochová, P. Fabián, M. Moulis +5 more

    2008Oncology Report6 citations Open access

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22. Chromatin differentiation of white blood cells decreases DSB damage induction, prevents functional assembly of repair foci, but has no influence on protrusion of heterochromatic DSBs into the low-dense chromatin

    M. Falk, E. Lukášová, I. Falková, L. Štefančíková +6 more

    2014Journal of Radiation Research5 citations Open access

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23. Frequent Chromatin Rearrangements in Myelodysplastic Syndromes - What Stands Behind? (myelodysplasticsyndromes/chromosomalrearrangements/chromosome5deletions/chromatinstructure/ architectureofthecellnucleus/chromothripsis)

    M. Falk, I. Falková, E. Lukášová, K. Michalová +3 more

    20144 citations

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24. Prognostic impact of p 53 aberrations for R-CHOP-treated patients with diffuse large B-cell lymphoma

    L. Štefančíková, M. Moulis, P. Fabián, I. Vášová +8 more

    4 citations

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25. Space and time in the universe of the cell nucleus after ionizing radiation attacks: a comparison of cancer and non-cancer cell response

    M. Hausmann, Charlotte Neitzel, H. Hahn, Ruth Winter +5 more

    2021Proceedings of The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response3 citations Open access

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26. Loss of the p 53 tumor suppressor activity is associated with negative prognosis of mantle cell lymphoma

    L. Štefančíková, M. Moulis, P. Fabián, B. Ravčuková +6 more

    3 citations

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27. Nanoscale topology of γH2AX and 53BP1 foci in U87 cancer cells and normal NHDF after high-LET radiation-induced DSB repair.

    K. Küntzelmann, Laura R Pardo, Myriam Schäfer, Jonas Weidner +6 more

    2026Nanoscale2 citations Open access

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28. γH2AX/53BP1 foci as a potential pre-treatment marker of HNSCC tumors radiosensitivity – preliminary methodological study and discussion

    M. Falk, Z. Hořáková, M. Svobodová, M. Masařík +7 more

    20172 citations

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29. γH2AX/53BP1 foci as a potential pre-treatment marker of HNSCC tumors radiosensitivity – preliminary methodological study and discussion

    M. Falk, Z. Hořáková, M. Svobodová, M. Masařík +7 more

    2017European Physical Journal D : Atomic, Molecular and Optical Physics1 citations

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30. Freezing processes in cryoprotective solutions of Me2SO, trehalose and antifreeze protein ApAFP752 and their impact on chromatin condition of cryopreserved cells

    Martin Golan, S. Sedláková, J. Mičová, J. Šebera +8 more

    20151 citations

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31. From survival of irradiated mice to modern molecular insights: a seventy-year journey in radiobiology at the institute of biophysics, Czech academy of sciences

    Jiří Toufar, Lucie Toufarová, I. Falková, Alena Bačı́ková +1 more

    2025European Biophysics Journal0 citations Open access

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32. DNA repair in head and neck tumor cells and possibilities of its monitoring to estimate individual tumor radioresistance and selection of optimal primary treatment.

    Z. Hořáková, J. Gumulec, O. Kopecna, E. Pagáčová +7 more

    2020Casopis lekaru ceskych0 citations

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33. Sequestration of MBnL 1 Protein by Mutant ZnF 9 mRnA in Lymphocytes of Patients with Myotonic Dystrophy type 2

    O. Souček, S. Voháňka, J. Zaorálková, I. Falková +3 more

    20190 citations

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34. Critical defects in cryopreserved cell nuclei: dna structure changes

    M. Falk, I. Falková, E. Pagáčová, O. Kopecna +7 more

    2018Cryobiology0 citations

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35. Viability of cryopreserved cells, state of their nuclei, and properties of cryoprotectants

    M. Falk, I. Falková, E. Pagáčová, Alena Bačı́ková +11 more

    20160 citations

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36. of the antifreeze protein AFP 752 , trehalose and dimethyl sulfoxide cryoprotection mechanism : correlation with cryopreserved cell viability †

    Irena Kratochv́, Lova, Martin Golan, Karel Pomeisl +11 more

    20160 citations

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37. Frequent chromatin rearrangements in myelodysplastic syndromes--what stands behind?

    E. Pagáčová, M. Falk, I. Falková, E. Lukášová +4 more

    2014Folia biologica0 citations Open access

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38. Primary and secondary clustering of DSB repair foci and repair kinetics compared for γ-rays, protons of different energies and high-LET 20Ne ions

    M. Falk, E. Lukášová, I. Falková, M. Davídková +8 more

    2014Journal of Radiation Research0 citations Open access

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39. Comparison of DNA gH2AX/53BP1 foci formation, nucleardistribution and DNA double-strand break repair for skinfibroblasts and lymphocytes either irradiated with gamma-raysor incubated with hydrogen peroxide.

    E. Baranova, L. Štefančíková, I. Falková, S. Kozubek +3 more

    20120 citations

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40. Sequestration of MBNL1 Protein by Mutant ZNF9 mRNA in Lymphocytes of Patients with Myotonic Dystrophy Type 2

    O. Souček, S. Voháňka, J. Zaorálková, I. Falková +3 more

    20120 citations

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41. Molecular genetic analysis of fetal tissues from a family affected by myotonic dystrophy

    Z. Lukáš, M. Falk, I. Falková, J. Feit +3 more

    20120 citations

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42. Current detection possibilities of unstable alleles in themyotonic dystrophy and Huntington's disease loci

    M. Falk, M. Vojtíṥková, Z. Lukáš, I. Falková +2 more

    20110 citations

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43. Colocalization of DMPK and ZNF9 transcripts with MBNL1 proteinin differentiated tissues from patients with myotonicdystrophy.

    Z. Lukáš, I. Falková, M. Falk, R. Hrabálková +1 more

    20100 citations

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44. Ribonuclear foci in differentiated tissues of patients withDM2.

    M. Falk, Z. Lukáš, I. Falková, R. Hrabálková +1 more

    20100 citations

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45. Complex analysis of cyclin D1 expression in mantle celllymphoma

    L. Štefančíková, M. Moulis, P. Fabián, I. Falková +2 more

    20090 citations

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46. cases detected mantle cell lymphoma: two cyclin D1-negative Complex analysis of cyclin D1 expression in

    L. Štefančíková, M. Moulis, P. Fabián, I. Falková +3 more

    20090 citations

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47. [Our experience in using fluorescence in situ hybridization FISH-Uro Vysion in diagnostics of urothelial carcinoma].

    V. Vit, D. Pacík, A. Čermák, I. Falková +5 more

    2009Ceskoslovenska patologie0 citations

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48. In situ hybridization analysis of DMPK mRNA in differentiatedtissues of the myotonic dystrophy patients.

    Z. Lukáš, I. Falková, M. Falk

    20080 citations

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49. Complex analysis of cyclin D1 and p53 in mantle cell lymphoma

    J. Šmardová, L. Štefančíková, M. Moulis, P. Fabián +5 more

    20080 citations

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