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J. Lacapere · SciRah

Researcher profile · Semantic Scholar

J. Lacapere

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J. Lacapere — researcher profile on SciRah

h-index: 31
Works: 103
Citations: 5,681

Most-cited papers

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function.
V. Papadopoulos, M. Baraldi, T. Guilarte, T. Knudsen +7 more
2006TIPS - Trends in Pharmacological Sciences1,396 citations Open access
Semantic Scholar
Interaction of a Golgi-associated kinesin-like protein with Rab6.
A. Echard, F. Jollivet, Olivier Martinez, J. Lacapere +3 more
1998Science537 citations
Semantic Scholar
Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis.
J. Lacapere, V. Papadopoulos
2003Steroids342 citations
Semantic Scholar
Identification and Characterization of Cholest-4-en-3-one, Oxime (TRO19622), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
T. Bordet, B. Buisson, M. Michaud, C. Drouot +14 more
2007Journal of Pharmacology and Experimental Therapeutics255 citations
Semantic Scholar
Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor.
N. Jamin, J. Neumann, M. Ostuni, T. N. H. Vu +6 more
2005Molecular Endocrinology235 citations Open access
Semantic Scholar
Bio-Beads: an efficient strategy for two-dimensional crystallization of membrane proteins.
J. Rigaud, G. Mosser, J. Lacapere, A. Olofsson +2 more
1997Journal of Structural Biology215 citations
Semantic Scholar
Determining membrane protein structures: still a challenge!
J. Lacapere, E. Pebay-Peyroula, J. Neumann, C. Etchebest
2007TIBS -Trends in Biochemical Sciences. Regular ed181 citations
Semantic Scholar
In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding.
F. Delavoie, Hua Li, Matthew J Hardwick, J. Robert +6 more
2003Biochemistry175 citations
Semantic Scholar
Structural and functional study of reconstituted peripheral benzodiazepine receptor.
J. Lacapere, F. Delavoie, Hua Li, G. Péranzi +3 more
2001Biochemical and Biophysical Research Communications - BBRC163 citations
Semantic Scholar
Acting on actin: the electric motility assay
D. Riveline, Albrecht Ott, F. Jülicher, D. A. Winkelmann +6 more
1998European Biophysics Journal135 citations
Semantic Scholar
TRO40303, a New Cardioprotective Compound, Inhibits Mitochondrial Permeability Transition
S. Schaller, Stéphanie Paradis, G. Ngoh, R. Assaly +10 more
2010Journal of Pharmacology and Experimental Therapeutics123 citations
Semantic Scholar
Combinatorial discovery of fluorescent pharmacophores by multicomponent reactions in droplet arrays.
O. Burchak, L. Mugherli, M. Ostuni, J. Lacapere +1 more
2011Journal of the American Chemical Society117 citations Open access
Semantic Scholar
Class-B GPCR activation: is ligand helix-capping the key?
J. Neumann, A. Couvineau, Samuel Murail, J. Lacapere +2 more
2008TIBS -Trends in Biochemical Sciences. Regular ed105 citations
Semantic Scholar
Normal mode-based fitting of atomic structure into electron density maps: application to sarcoplasmic reticulum Ca-ATPase.
K. Hinsen, N. Reuter, J. Navaza, D. Stokes +1 more
2005Biophysical Journal88 citations Open access
Semantic Scholar
Protoporphyrin IX binding and transport by recombinant mouse PBR.
Gregor Wendler, P. Lindemann, J. Lacapere, V. Papadopoulos
2003Biochemical and Biophysical Research Communications - BBRC76 citations
Semantic Scholar
Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding.
Samuel Murail, J. Robert, Y. Coïc, J. Neumann +5 more
2008Biochimica et Biophysica Acta74 citations Open access
Semantic Scholar
TLR9 Activation Induces Normal Neutrophil Responses in a Child with IRAK-4 Deficiency: Involvement of the Direct PI3K Pathway
C. Hoarau, B. Gerard, E. Lescanne, Dominique Henry +8 more
2007Journal of Immunology72 citations Open access
Semantic Scholar
Peptide Agonist Docking in the N-terminal Ectodomain of a Class II G Protein-coupled Receptor, the VPAC1 Receptor
Yossan-Var Tan, A. Couvineau, Samuel Murail, E. Ceraudo +3 more
2006Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Transconformations of the SERCA1 Ca-ATPase: a normal mode study.
N. Reuter, K. Hinsen, J. Lacapere
2003Biophysical Journal63 citations Open access
Semantic Scholar
How to make tubular crystals by reconstitution of detergent-solubilized Ca2(+)-ATPase.
H. S. Young, J. Rigaud, J. Lacapere, Laxma G. Reddy +1 more
1997Biophysical Journal63 citations Open access
Semantic Scholar
Identification of Residues within Human Glycoprotein VI Involved in the Binding to Collagen
Christelle Lecut, V. Arocas, H. Ulrichts, A. Elbaz +4 more
2004Journal of Biological Chemistry59 citations Open access
Semantic Scholar
A Hexameric Transmembrane Pore Revealed by Two-dimensional Crystallization of the Large Mechanosensitive Ion Channel (MscL) ofEscherichia coli*
N. Saint, J. Lacapere, Li-Qun Gu, A. Ghazi +2 more
1998Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Identification of Cytoplasmic Domains of hVPAC1 Receptor Required for Activation of Adenylyl Cyclase
A. Couvineau, J. Lacapere, Yossan-Var Tan, C. Rouyer‐Fessard +2 more
2003Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Variants of the xeroderma pigmentosum variant gene (POLH) are associated with melanoma risk.
Julie Di Lucca, M. Guedj, J. Lacapere, M. Fargnoli +12 more
2009European Journal of Cancer47 citations
Semantic Scholar
Overexpression of Translocator protein TSPO in inflammatory bowel disease: potential diagnostic and treatment value
M. Ostuni, Leeyah Issop, G. Péranzi, F. Walker +4 more
2010Inflammatory Bowel Diseases46 citations Open access
Semantic Scholar
The vasoactive intestinal peptide (VIP) alpha-Helix up to C terminus interacts with the N-terminal ectodomain of the human VIP/Pituitary adenylate cyclase-activating peptide 1 receptor: photoaffinity, molecular modeling, and dynamics.
E. Ceraudo, Samuel Murail, Yossan-Var Tan, J. Lacapere +3 more
2008Molecular Endocrinology37 citations Open access
Semantic Scholar
Translocator Protein-Mediated Stabilization of Mitochondrial Architecture during Inflammation Stress in Colonic Cells
Leeyah Issop, M. Ostuni, Sunghoon Lee, M. Laforge +6 more
2016PLoS ONE36 citations Open access
Semantic Scholar
A Central Cysteine Residue Is Essential for the Thermal Stability and Function of SUMO-1 Protein and SUMO-1 Peptide-Protein Conjugates.
H. Drobecq, E. Boll, M. Sénéchal, R. Desmet +5 more
2016Bioconjugate chemistry35 citations Open access
Semantic Scholar
Conformation of Ca(2+)-ATPase in two crystal forms. Effects of Ca2+, thapsigargin, adenosine 5'-(beta, gamma-methylene)triphosphate), and chromium(III)-ATP on crystallization.
D. Stokes, J. Lacapere
1994Journal of Biological Chemistry34 citations
Semantic Scholar
Translocator protein (18 kDa) is involved in primitive erythropoiesis in zebrafish
C. Rampon, Mohamed Rouzaffour, M. Ostuni, P. Dufourcq +5 more
2009The FASEB Journal31 citations Open access
Semantic Scholar
Insight into structural features of TSPO: implications for drug development
J. Lacapere, Luminita Duma, S. Finet, M. Kassiou +1 more
2019TIPS - Trends in Pharmacological Sciences27 citations Open access
Semantic Scholar
Identification of amino acid residues photolabeled with 8-azidoadenosine 5'-diphosphate in the catalytic site of sarcoplasmic reticulum Ca-ATPase.
J. Lacapere, J. Garin, B. Trinnaman, N. Green
1993Biochemistry27 citations
Semantic Scholar
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl− secretion in HT‐29 human colon cancer cells
M. Ostuni, R. Ducroc, G. Péranzi, M. Tonon +2 more
2007Biology of the Cell25 citations
Semantic Scholar
Functional characterization and expression of PBR in rat gastric mucosa: stimulation of chloride secretion by PBR ligands.
M. A. Ostuni, K. Marazova, G. Péranzi, B. Vidić +3 more
2004American Journal of Physiology - Gastrointestinal and Liver Physiology24 citations Open access
Semantic Scholar
Erythroid-Progenitor-Targeted Gene Therapy Using Bifunctional TFR1 Ligand-Peptides in Human Erythropoietic Protoporphyria.
A. Mirmiran, C. Schmitt, T. Lefèbvre, H. Manceau +13 more
2019American Journal of Human Genetics23 citations Open access
Semantic Scholar
CX3CL1 homo-oligomerization drives cell-to-cell adherence
M. Ostuni, P. Hermand, E. Saindoy, N. Guillou +12 more
2020Scientific Reports22 citations Open access
Semantic Scholar
Probing the gel to liquid-crystalline phase transition and relevant conformation changes in liposomes by (13)C magic-angle spinning NMR spectroscopy.
Rudra N. Purusottam, Lucile Sénicourt, J. Lacapere, P. Tekely
2015Biochimica et Biophysica Acta22 citations Open access
Semantic Scholar
Mouse TSPO in a lipid environment interacting with a functionalized monolayer.
David Teboul, S. Beaufils, J. Taveau, Soria Iatmanen-Harbi +4 more
2012Biochimica et Biophysica Acta22 citations Open access
Semantic Scholar
Distribution, pharmacological characterization and function of the 18 kDa translocator protein in rat small intestine
M. Ostuni, G. Péranzi, Robert A. Ducroc, M. Fasseu +4 more
2009Biology of the Cell22 citations Open access
Semantic Scholar
Structural Studies of a Stabilized Phosphoenzyme Intermediate of Ca2+-ATPase*
D. Stokes, F. Delavoie, W. J. Rice, P. Champeil +2 more
2005Journal of Biological Chemistry22 citations Open access
Semantic Scholar
The 9 A projection structure of cytochrome b6f complex determined by electron crystallography.
P. Bron, J. Lacapere, C. Breyton, G. Mosser
1999Journal of Molecular Biology22 citations
Semantic Scholar
Association between endothelin receptor B nonsynonymous variants and melanoma risk.
N. Soufir, R. Meziani, J. Lacapere, G. Bertrand +11 more
2005Journal of the National Cancer Institute21 citations
Semantic Scholar
A French CDK4-positive melanoma family with a co-inherited EDNRB mutation.
N. Soufir, L. Ollivaud, G. Bertrand, J. Lacapere +8 more
2007Journal of dermatological science (Amsterdam)20 citations
Semantic Scholar
The reaction mechanism of Ca2+‐ATPase of sarcoplasmic reticulum
J. Lacapere, F. Guillain
199319 citations
Semantic Scholar
TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood
I. Marginedas-Freixa, C. Hattab, G. Bouyer, F. Hallé +11 more
2016Scientific Reports18 citations Open access
Semantic Scholar
Chimeric Fc receptors identify ligand binding regions in human glycoprotein VI.
B. Dumont, I. Minullina, S. Loyau, R. Monteiro +3 more
2006Journal of Molecular Biology18 citations
Semantic Scholar
Construction and validation of an atomic model for bacterial TSPO from electron microscopy density, evolutionary constraints, and biochemical and biophysical data.
K. Hinsen, Aurore Vaitinadapoule, M. Ostuni, C. Etchebest +1 more
2015Biochimica et Biophysica Acta16 citations Open access
Semantic Scholar
Reversal of the sarcoplasmic reticulum ATPase cycle by substituting various cations for magnesium. Phosphorylation and ATP synthesis when Ca2+ replaces Mg2+.
E. Mintz, J. Lacapere, Florent Guillain
1990Journal of Biological Chemistry16 citations Open access
Semantic Scholar
ATP‐INDUCED CONFORMATIONAL TRANSITIONS OF THE Ca2+‐ATPase OF SARCOPLASMIC RETICULUM
Y. Dupont, N. Bennett, J. Lacapere
1982Annals of the New York Academy of Sciences15 citations
Semantic Scholar
Targeting hIAPP fibrillation: A new paradigm to prevent β-cell death?
G. Guillemain, J. Lacapere, Lucie Khemtemourian
2022Biochimica et Biophysica Acta - Biomembranes14 citations Open access
Semantic Scholar

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