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A. Wernitznig · SciRah

Researcher profile · Semantic Scholar

A. Wernitznig

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A. Wernitznig — researcher profile on SciRah

h-index: 14
Works: 36
Citations: 1,580

Most-cited papers

The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
Kirsten Aigner, B. Dampier, L. Descovich, M. Mikula +12 more
2007Oncogene651 citations Open access
Semantic Scholar
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers
Takahiro Ito, Michael J. Young, Ruitong Li, Sidharth S. Jain +18 more
2021Nature Genetics134 citations
Semantic Scholar
Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells
Simone Lieb, Silvia Blaha-Ostermann, Elizabeth Kamper, Janine Rippka +16 more
2019bioRxiv125 citations Open access
Semantic Scholar
First-in-class ruthenium anticancer drug (KP1339/IT-139) induces an immunogenic cell death signature in colorectal spheroids in vitro.
Debora Wernitznig, K. Kiakos, G. del Favero, N. Harrer +6 more
2019Metallomics112 citations Open access
Semantic Scholar
The transcription factor ZEB1 (δEF1) represses Plakophilin 3 during human cancer progression
Kirsten Aigner, L. Descovich, M. Mikula, Aneesa Sultan +12 more
2007FEBS Letters91 citations Open access
Semantic Scholar
Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms
C. Unger, N. Kramer, D. Unterleuthner, M. Scherzer +13 more
2017Oncogene77 citations
Semantic Scholar
Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
D. Rudolph, M. Impagnatiello, C. Blaukopf, Christoph Sommer +14 more
2015Journal of Pharmacology and Experimental Therapeutics66 citations Open access
Semantic Scholar
High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts
A. Rudisch, Matthew R. Dewhurst, Luminita Gabriela Horga, N. Kramer +7 more
2015PLoS ONE50 citations Open access
Semantic Scholar
hGPR87 contributes to viability of human tumor cells
S. Glatt, Daniel Halbauer, S. Heindl, A. Wernitznig +5 more
2008International Journal of Cancer49 citations
Semantic Scholar
Purification and nucleic-acid-binding properties of a Saccharomyces cerevisiae protein involved in the control of ploidy.
Viktoria Weber, A. Wernitznig, G. Hager, M. Harata +2 more
1997European Journal of Biochemistry47 citations
Semantic Scholar
Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids.
Debora Wernitznig, S. Meier-Menches, Klaudia Cseh, S. Theiner +7 more
2020Metallomics39 citations Open access
Semantic Scholar
Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist
J. M. García-Martínez, Shirley Wang, C. Weishaeupl, A. Wernitznig +14 more
2020Molecular Cancer Therapeutics34 citations Open access
Semantic Scholar
The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy
M. Sanderson, M. H. Hofmann, P. Garin-Chesa, N. Schweifer +11 more
2017Molecular Cancer Therapeutics28 citations Open access
Semantic Scholar
Ordino: a visual cancer analysis tool for ranking and exploring genes, cell lines and tissue samples
Marc Streit, S. Gratzl, Holger Stitz, A. Wernitznig +2 more
2019Bioinform.14 citations Open access
Semantic Scholar
A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer
T. Zoranovic, J. Manent, Lee F. Willoughby, Ricardo Matos de Simoes +14 more
2018PLoS Genetics14 citations Open access
Semantic Scholar
Abstract 4865: BI 907828: A highly potent MDM2 inhibitor with low human dose estimation, designed for high-dose intermittent schedules in the clinic
Joerg Rinnenthal, D. Rudolph, Sophia M. Blake, A. Gollner +8 more
2018Experimental and Molecular Therapeutics9 citations
Semantic Scholar
Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells
D. Lamb, A. Rust, A. Rudisch, Tobias Glüxam +7 more
2020OncoTarget7 citations Open access
Semantic Scholar
TourDino: A Support View for Confirming Patterns in Tabular Data
Klaus Eckelt, Patrick Adelberger, T. Zichner, A. Wernitznig +1 more
2019EuroVA@EuroVis6 citations
Semantic Scholar
Abstract 4866: BI 907828: A novel, potent MDM2 inhibitor that induces antitumor immunologic memory and acts synergistically with an anti-PD-1 antibody in syngeneic mouse models of cancer
D. Rudolph, M. Reschke, Sophia M. Blake, J. Rinnenthal +9 more
2018Experimental and Molecular Therapeutics6 citations
Semantic Scholar
Combining BET inhibition with SMAC mimetics restricts tumor growth and triggers immune surveillance in preclinical cancer models
Ksenija Slavic Obradovic, Florian Ebner, Artem V. Artemov, Martina Miotto +21 more
2025Cell Reports Medicine4 citations Open access
Semantic Scholar
Abstract 4868: BI 907828: A novel, potent MDM2 inhibitor that is suitable for high-dose intermittent schedules
D. Rudolph, A. Gollner, Sophia M. Blake, J. Rinnenthal +8 more
2018Experimental and Molecular Therapeutics4 citations
Semantic Scholar
Ordino: a visual analysis tool for ranking and exploring genes, cell lines, and tissue samples
Marc Streit, S. Gratzl, Holger Stitz, A. Wernitznig +2 more
2018bioRxiv3 citations Open access
Semantic Scholar
Abstract 3197: BI-907828, a novel and potent MDM2-p53 antagonist, acts synergistically in a triple combination with anti-PD-1 and anti-LAG-3 antibodies in syngeneic mouse models of cancer
D. Rudolph, Ulrike Weyer-Czernilofsky, M. Reschke, Martina M Sykora +7 more
2019Immunology2 citations
Semantic Scholar
Abstract 2051: BI 905711, a novel CDH17-targeting TRAILR2 agonist, effectively triggers tumor cell apoptosis and tumor regressions selectively in CDH17-positive colorectal cancer models
J. M. García-Martínez, A. Wernitznig, Joerg Rinnenthal, M. Impagnatiello +5 more
2019Experimental and Molecular Therapeutics2 citations
Semantic Scholar
Efficacy of the Plk Inhibitor Volasertib in Preclinical Models of AML
D. Rudolph, Christoph Albrecht, Lena Geiselmann, M. Impagnatiello +4 more
20142 citations
Semantic Scholar
Abstract 1951: SMAC mimetic and BET inhibitor - a promising combination for solid cancer treatment
Paula-Elena Traexler, D. Arnold, F. Ebner, Ksenija Slavic-Obradovic +19 more
2021Molecular and Cellular Biology/Genetics1 citations
Semantic Scholar
Abstract 3227: CLIFF, a bioinformatics software tool to explore molecular differences between two sets of cancer cell lines
A. Wernitznig, Jesse J. Lipp, T. Zichner, D. Gerlach +8 more
2020Clinical research1 citations
Semantic Scholar
Abstract 2560: Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells
Simone Lieb, Silvia Blaha-Ostermann, Elizabeth Kamper, Katharina Ehrenhöfer-Wölfer +10 more
2019Molecular and Cellular Biology / Genetics1 citations
Semantic Scholar
Abstract 2330: BI5: a novel SMAC mimetic that triggers tumor cell death and potentiates PD-1 mediated cancer therapy
M. Reschke, M. Impagnatiello, Ulrich Reiser, D. Scharn +14 more
20171 citations
Semantic Scholar
A Toy Model of Chemical Reaction Networks
G. Benko, P. Stadler, Christoph Flamm, I. Hofacker +18 more
20021 citations
Semantic Scholar
A Variation on Algorithms for Pairwise Global Alignments
P. Stadler, I. Hofacker, P. Schuster, Ingrid G. Abfalter +22 more
20011 citations
Semantic Scholar
Abstract 6221: Targeting IAP in cancer: BI 891065 a potent small molecule SMAC mimetic that synergizes with immune checkpoint inhibition
M. Aichinger, V. Santoro, Ksenija Slavic-Obradovic, S. Ruhland +26 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Author response: Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells
Simone Lieb, Silvia Blaha-Ostermann, Elizabeth Kamper, Janine Rippka +16 more
20190 citations Open access
Semantic Scholar
Abstract 3987: Predicting MCL1 inhibitor sensitivity in large cell line panels using a gene expression signature
A. Wernitznig, D. Rudolph, Matthias Samwer, N. Schweifer +9 more
2019Clinical research0 citations
Semantic Scholar
Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia
D. Rudolph, M. Impagnatiello, C. Blaukopf, Christoph Sommer +13 more
20140 citations
Semantic Scholar
Recombination and the Structure of Globular Proteins
J. Hackermüller, P. Stadler, I. Hofacker, P. Schuster +22 more
20010 citations
Semantic Scholar

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