Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

G. Noronha · SciRah

Researcher profile · Semantic Scholar

G. Noronha

Share profile

G. Noronha — researcher profile on SciRah

h-index: 29
Works: 82
Citations: 3,127

Most-cited papers

Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera.
G. Wernig, M. Kharas, R. Okabe, Sandra A. Moore +15 more
2008Cancer Cell413 citations Open access
Semantic Scholar
TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations
A. Pardanani, J. Hood, T. Lasho, R. Levine +9 more
2007Leukemia276 citations Open access
Semantic Scholar
Efficacy and Safety of Suprachoroidal CLS-TA for Macular Edema Secondary to Noninfectious Uveitis: Phase 3 Randomized Trial.
S. Yeh, R. Khurana, Milan Shah, C. R. Henry +4 more
2020Ophthalmology (Rochester, Minn.)172 citations Open access
Semantic Scholar
Selective inhibition of JAK2-driven erythroid differentiation of polycythemia vera progenitors.
I. Geron, Annelie Abrahamsson, C. Barroga, E. Kavalerchik +9 more
2008Cancer Cell148 citations Open access
Semantic Scholar
Molecular recognition in micelles: the roles of hydrogen bonding and hydrophobicity in adenine-thymine base-pairing in SDS micelles
J. Nowick, Jenny S. Chen, G. Noronha
1993138 citations
Semantic Scholar
Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates
G. Yiu, S. Chung, I. N. Mollhoff, U. Nguyen +4 more
2020Molecular Therapy: Methods & Clinical Development131 citations Open access
Semantic Scholar
An improved method for the synthesis of enantiomerically pure amino acid ester isocyanates
J. Nowick, Noel A. Powell, T. M. Nguyen, G. Noronha
1992120 citations
Semantic Scholar
Phosphoinositide 3-kinase γ/δ inhibition limits infarct size after myocardial ischemia/reperfusion injury
J. Doukas, W. Wrasidlo, G. Noronha, E. Dneprovskaia +6 more
2006Proceedings of the National Academy of Sciences of the United States of America119 citations Open access
Semantic Scholar
Aerosolized Phosphoinositide 3-Kinase γ/δ Inhibitor TG100-115 [3-[2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease
J. Doukas, L. Eide, K. Stebbins, Adrienne Racanelli-Layton +8 more
2009Journal of Pharmacology and Experimental Therapeutics114 citations
Semantic Scholar
Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits.
Lea Scheppke, E. Aguilar, R. Gariano, R. Jacobson +10 more
2008Journal of Clinical Investigation111 citations Open access
Semantic Scholar
Suprachoroidal Triamcinolone Acetonide for Retinal Vein Occlusion: Results of the Tanzanite Study.
P. Campochiaro, C. Wykoff, David M. Brown, D. Boyer +3 more
2017Ophthalmology Retina103 citations
Semantic Scholar
Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis
D. Goldstein, D. Do, G. Noronha, Jennifer M. Kissner +2 more
2016Translational Vision Science & Technology87 citations Open access
Semantic Scholar
Synthesis of Peptide Isocyanates and Isothiocyanates.
J. Nowick, D. Holmes, G. Noronha, Eric M. Smith +2 more
1996Journal of Organic Chemistry81 citations
Semantic Scholar
Suprachoroidally injected pharmacological agents for the treatment of chorio‐retinal diseases: a targeted approach
Z. Habot-Wilner, G. Noronha, C. Wykoff
2019Acta ophthalmologica76 citations
Semantic Scholar
Topical Administration of a Multi-Targeted Kinase Inhibitor Suppresses Choroidal Neovascularization and Retinal Edema
J. Doukas, S. Mahesh, Naoyasu Umeda, S. Kachi +12 more
2008Journal of Cellular Physiology75 citations Open access
Semantic Scholar
SUPRACHOROIDAL INJECTION OF TRIAMCINOLONE ACETONIDE, CLS-TA, FOR MACULAR EDEMA DUE TO NONINFECTIOUS UVEITIS: A Randomized, Phase 2 Study (DOGWOOD).
S. Yeh, S. Kurup, Robert C. Wang, C. S. Foster +3 more
2019Retina74 citations
Semantic Scholar
Suprachoroidal Triamcinolone Acetonide for Diabetic Macular Edema: The HULK Trial.
C. Wykoff, R. Khurana, S. Lampen, G. Noronha +3 more
2018Ophthalmology Retina65 citations
Semantic Scholar
Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury.
J. Doukas, W. Wrasidlo, G. Noronha, E. Dneprovskaia +6 more
2006Proceedings of the National Academy of Sciences of the United States of America63 citations
Semantic Scholar
AN ARTIFICIAL BETA -SHEET COMPRISING A MOLECULAR SCAFFOLD, A BETA -STRAND MIMIC, AND A PEPTIDE STRAND
J. Nowick, D. Holmes, G. Mackin, G. Noronha +2 more
199657 citations
Semantic Scholar
Molecular scaffolds. I. Intramolecular hydrogen bonding in a family of di- and triureas
J. Nowick, Noel A. Powell, E. Martinez, Eric M. Smith +1 more
199256 citations
Semantic Scholar
TG 101209 , a small molecule JAK 2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK 2 V 617 F and MPL W 515 L / K mutations
A. Pardanani, J. Hood, T. Lasho, R. Levine +9 more
200754 citations
Semantic Scholar
Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction.
M. Palanki, E. Dneprovskaia, J. Doukas, Richard M Fine +9 more
2007Journal of Medicinal Chemistry54 citations Open access
Semantic Scholar
Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays.
G. Noronha, K. Barrett, A. Boccia, T. Brodhag +31 more
2007Bioorganic & Medicinal Chemistry Letters47 citations Open access
Semantic Scholar
Molecular Scaffolds. 2. Intramolecular Hydrogen Bonding in 1,2-Diaminoethane Diureas
J. Nowick, Muna Abdi, Keith A. Bellamo, J. Love +4 more
199546 citations
Semantic Scholar
Molecular Scaffolds. 3. An Artificial Parallel .beta.-Sheet
J. Nowick, Eric M. Smith, G. Noronha
199543 citations
Semantic Scholar
Inhibitors of ABL and the ABL-T315I mutation.
G. Noronha, Jian'guo Cao, Chun P. Chow, E. Dneprovskaia +12 more
2008Current Topics in Medicinal Chemistry42 citations
Semantic Scholar
Choroidal Changes after Suprachoroidal Injection of Triamcinolone in Eyes with Macular Edema Secondary to Retinal Vein Occlusion
Alex S. Willoughby, Vivian S. Vuong, David Cunefare, Sina Farsiu +3 more
2017American journal of ophthalmology-glaucoma41 citations Open access
Semantic Scholar
Development of prodrug 4-chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl benzoate (TG100801): a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration.
M. Palanki, Hideo Akiyama, P. Campochiaro, Jian'guo Cao +24 more
2008Journal of Medicinal Chemistry41 citations Open access
Semantic Scholar
Dendrimer-magnetic nanoparticles as multiple stimuli responsive and enzymatic drug delivery vehicle
S. Chandra, G. Noronha, S. Dietrich, H. Lang +1 more
201533 citations
Semantic Scholar
Suprachoroidal Space Alterations Following Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients With Diabetic Macular Edema.
S. Lampen, R. Khurana, G. Noronha, David M. Brown +1 more
2018Ophthalmic Surgery Lasers and Imaging Retina29 citations
Semantic Scholar
Discovery and preliminary structure-activity relationship studies of novel benzotriazine based compounds as Src inhibitors.
G. Noronha, K. Barrett, Jian'guo Cao, E. Dneprovskaia +20 more
2006Bioorganic & Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Isoform-selective PI3K inhibitors as novel therapeutics for the treatment of acute myocardial infarction.
J. Doukas, W. Wrasidlo, G. Noronha, E. Dneprovskaia +2 more
2007Biochemical Society Transactions21 citations
Semantic Scholar
The design and preliminary structure-activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes.
Jian'guo Cao, Richard M Fine, Colleen Gritzen, J. Hood +12 more
2007Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
Heterogenized polymetallic catalysts: Part III. Catalytic air oxidation of alcohols by Pd(II) complexed to a polyphenylene polymer containing β-di- and tri-ketone surface ligands
G. Noronha, P. Henry
199716 citations
Semantic Scholar
An Improved Method for the Synthesis of Enantiomerically Pure Amino Acid Ester Isocyanates.
J. Nowick, Noel A. Powell, T. M. Nguyen, G. Noronha
199316 citations
Semantic Scholar
Metabolism and Pharmacokinetics of a Novel Src Kinase Inhibitor TG100435 ([7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine) and Its Active N-Oxide Metabolite TG100855 ([7-(2,6-Dichloro-phenyl)-5-methylbenzo[1,2,4]triazin-3-yl]-{4-[2-(1-oxy-pyrro
Steven Hu, R. Soll, S. Yee, D. Lohse +11 more
2007Drug Metabolism And Disposition15 citations Open access
Semantic Scholar
Heterogenized polymetallic catalysts Part II. Oxidation of 3,5-di-t-butylphenol by Cu(II), Fe(III) and Pd(II) complexed to a polyphenylene polymer containing ß-di- and triketone surface ligands; an improved catalyst system
P. Henry, Xiao-Li Ma, G. Noronha, K. Zaw
199511 citations
Semantic Scholar
Development of novel benzotriazines for drug discovery
M. Palanki, Jian'guo Cao, Chun P. Chow, E. Dneprovskaia +7 more
2009Expert Opinion on Drug Discovery10 citations
Semantic Scholar
TG101209, a Selective JAK2 Kinase Inhibitor, Suppresses Endogenous and Cytokine-Supported Colony Formation from Hematopoietic Progenitors Carrying JAK2V617F or MPLW515K/L Mutations.
A. Pardanani, J. Hood, T. Lasho, G. Noronha +6 more
200610 citations
Semantic Scholar
Selective Inhibition of JAK2 Driven Erythroid Differentiation of Polycythemia Vera Progenitors
I. Geron, Annelie Abrahamsson, C. Barroga, Edward Kavelerchik +9 more
20077 citations
Semantic Scholar
TG101348, a potent, highly selective JAK2 inhibitor, inhibits colony formation in stem cells from polycythemia vera patients and prevents JAK2V617F-mediated splenomegaly and death in a mouse model
J. Hood, J. Doukas, Michael Martin, G. Noronha +2 more
20076 citations
Semantic Scholar
Primary Cell Experiments with TG101348, a JAK2-Selective Inhibitor, in the Presence of Myeloproliferative Disorder-Associated JAK2V617F, MPLW515L/K, and JAK2 Exon 12 Mutations.
T. Lasho, C. Finke, J. Hood, R. Soll +9 more
20076 citations
Semantic Scholar
A NOVEL HYDROGEN-BONDED DIMER CONTAINING A 16-MEMBERED RING
J. Nowick, V. Antonovich, G. Noronha, J. Ziller
19956 citations
Semantic Scholar
Preparation of a new class of cleavable surfactants based on the siliconcarbon bond
G. Noronha, Khanhlinh Nguyen
19995 citations
Semantic Scholar
JAK2 Inhibitors for the Treatment of Myeloprolifertive Disorders.
J. Hood, J. Cao, E. Hanna, D. Lohse +7 more
20064 citations
Semantic Scholar
Inhibition of JAK2 V617F-Induced Erythroid Skewing of Hematopoietic Stem Cell Differentiation with a Selective JAK2 Antagonist.
I. Geron, C. Barroga, J. Gotlib, E. Kavalerchik +10 more
20064 citations
Semantic Scholar
Efficacy of Suprachoroidal Aflibercept in a Laser Induced Choroidal Neovascularization Model
Samirkumar R. Patel, Jennifer M. Kissner, R. Farjo, V. Zarnitsyn +1 more
20163 citations
Semantic Scholar
A phase 1/2 open-label, safety and tolerability study of triamcinolone acetonide administered to the suprachoroidal space in patients with non-infectious uveitis
D. Goldstein, S. Srivastava, Q. Nguyen, G. Noronha +1 more
20153 citations
Semantic Scholar
A Dual VEGFR/JAK2 Kinase Inhibitor Suitable for Topical Delivery Inhibits Choroid Neovascularization in Mice
Z.-Z. Chen, Chi-Ching Mak, J. Renick, D. Lohse +6 more
20073 citations
Semantic Scholar
Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera.
G. Wernig, M. Kharas, R. Okabe, Sandra A. Moore +15 more
20073 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Soll×26
Invite
R. Soll — researcher profile on SciRah
J. Hood×24
Invite
J. Hood — researcher profile on SciRah
J. Doukas×14
Invite
J. Doukas — researcher profile on SciRah
Chi-Ching Mak×10
Invite
Chi-Ching Mak — researcher profile on SciRah

×9

Invite

A. Tefferi — researcher profile on SciRah

Invite

J. Nowick — researcher profile on SciRah

E. Dneprovskaia×9

Invite

E. Dneprovskaia — researcher profile on SciRah

Invite

D. Lohse — researcher profile on SciRah

Invite

J. Renick — researcher profile on SciRah

Michael Martin×8

Invite

Michael Martin — researcher profile on SciRah

Andrew K. McPherson×8

Invite

Andrew K. McPherson — researcher profile on SciRah

Invite

M. Palanki — researcher profile on SciRah