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Hideaki Tagashira · SciRah

Researcher profile · Semantic Scholar

Hideaki Tagashira

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Hideaki Tagashira — researcher profile on SciRah

h-index: 21
Works: 72
Citations: 1,206

Most-cited papers

Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice.
Nobuaki Matsui, Kazuki Takahashi, Mihoko Takeichi, Touma Kuroshita +10 more
2009Brain Research104 citations
Semantic Scholar
Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice
S. Moriguchi, Yasuharu Shinoda, Yui Yamamoto, Yuzuru Sasaki +3 more
2013PLoS ONE88 citations Open access
Semantic Scholar
Expression of a Truncated Form of the Endoplasmic Reticulum Chaperone Protein, σ1 Receptor, Promotes Mitochondrial Energy Depletion and Apoptosis*
N. Shioda, K. Ishikawa, Hideaki Tagashira, T. Ishizuka +2 more
2012Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Sigma1-receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice.
Hideaki Tagashira, Shenuarin Bhuiyan, N. Shioda, H. Hasegawa +2 more
2010American Journal of Physiology. Heart and Circulatory Physiology73 citations
Semantic Scholar
Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis.
Hideaki Tagashira, Yasuharu Shinoda, N. Shioda, K. Fukunaga
2014Biochimica et Biophysica Acta63 citations Open access
Semantic Scholar
The T‐type voltage‐gated calcium channel as a molecular target of the novel cognitive enhancer ST101: enhancement of long‐term potentiation and CaMKII autophosphorylation in rat cortical slices
S. Moriguchi, N. Shioda, Yui Yamamoto, Hideaki Tagashira +1 more
2012Journal of Neurochemistry60 citations Open access
Semantic Scholar
Fluvoxamine rescues mitochondrial Ca2+ transport and ATP production through σ(1)-receptor in hypertrophic cardiomyocytes.
Hideaki Tagashira, M. Bhuiyan, N. Shioda, K. Fukunaga
2014Life Science57 citations
Semantic Scholar
The role of SIGMAR1 gene mutation and mitochondrial dysfunction in amyotrophic lateral sclerosis.
K. Fukunaga, Yasuharu Shinoda, Hideaki Tagashira
2015Journal of Pharmacological Sciences56 citations Open access
Semantic Scholar
Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions
M. Bhuiyan, Hideaki Tagashira, N. Shioda, K. Fukunaga
2010Expert opinion on therapeutic targets55 citations
Semantic Scholar
Rivastigmine improves hippocampal neurogenesis and depression-like behaviors via 5-HT1A receptor stimulation in olfactory bulbectomized mice.
M. Islam, S. Moriguchi, Hideaki Tagashira, Kohji Fukunaga
2014Neuroscience49 citations
Semantic Scholar
Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer’s disease therapy
S. Moriguchi, T. Ishizuka, Y. Yabuki, N. Shioda +7 more
2018Molecular Psychiatry48 citations
Semantic Scholar
Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.
M. Bhuiyan, Hideaki Tagashira, K. Fukunaga
2011European Journal of Pharmacology43 citations
Semantic Scholar
Stimulation of σ1-receptor restores abnormal mitochondrial Ca²⁺ mobilization and ATP production following cardiac hypertrophy.
Hideaki Tagashira, Chen Zhang, Ying-Mei Lu, H. Hasegawa +3 more
2013Biochimica et Biophysica Acta41 citations
Semantic Scholar
Dehydroepiandrosterone-mediated stimulation of sigma-1 receptor activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.
M. Bhuiyan, Hideaki Tagashira, K. Fukunaga
2011Cardiovascular Therapeutics40 citations
Semantic Scholar
Diverse regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes.
Hideaki Tagashira, M. Bhuiyan, K. Fukunaga
2013American Journal of Physiology. Heart and Circulatory Physiology35 citations
Semantic Scholar
Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction.
Yasuharu Shinoda, Hideaki Tagashira, M. Bhuiyan, H. Hasegawa +2 more
2016Journal of Pharmacological Sciences33 citations Open access
Semantic Scholar
Distinct cardioprotective effects of 17&bgr;-estradiol and dehydroepiandrosterone on pressure overload–induced hypertrophy in ovariectomized female rats
Hideaki Tagashira, Shenuarin Bhuiyan, N. Shioda, K. Fukunaga
2011Menopause33 citations
Semantic Scholar
Crucial interactions between selective serotonin uptake inhibitors and sigma-1 receptor in heart failure.
M. Bhuiyan, Hideaki Tagashira, K. Fukunaga
2013Journal of Pharmacological Sciences32 citations Open access
Semantic Scholar
Na+/Ca2+ exchanger mediates cold Ca2+ signaling conserved for temperature-compensated circadian rhythms
Naohiro Kon, Hsin-Tzu Wang, Y. Kato, Kyouhei Uemoto +12 more
2021Science Advances26 citations Open access
Semantic Scholar
CaMKII activity is essential for improvement of memory‐related behaviors by chronic rivastigmine treatment
S. Moriguchi, Hideaki Tagashira, Yuzuru Sasaki, Jay Z. Yeh +3 more
2014Journal of Neurochemistry26 citations
Semantic Scholar
Vascular endothelial σ1-receptor stimulation with SA4503 rescues aortic relaxation via Akt/eNOS signaling in ovariectomized rats with aortic banding.
Hideaki Tagashira, T. Matsumoto, K. Taguchi, Chen Zhang +5 more
2013Circulation Journal23 citations Open access
Semantic Scholar
Reduced CaM Kinase II and CaM Kinase IV Activities Underlie Cognitive Deficits in NCKX2 Heterozygous Mice
S. Moriguchi, S. Kita, Y. Yabuki, Ryo Inagaki +7 more
2017Molecular Neurobiology21 citations
Semantic Scholar
Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes.
Hideaki Tagashira, M. Bhuiyan, Yasuharu Shinoda, Ichiro Kawahata +2 more
2022Journal of Pharmacological Sciences19 citations Open access
Semantic Scholar
Genetic knockout and pharmacologic inhibition of NCX2 cause natriuresis and hypercalciuria.
Y. Gotoh, S. Kita, M. Fujii, Hideaki Tagashira +4 more
2015Biochemical and Biophysical Research Communications - BBRC16 citations
Semantic Scholar
Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression
Yasuharu Shinoda, Hideaki Tagashira, M. Bhuiyan, H. Hasegawa +4 more
2016PLoS ONE15 citations Open access
Semantic Scholar
Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice.
S. Moriguchi, Tomoya Tanaka, Hideaki Tagashira, T. Narahashi +1 more
2013Behavioural Brain Research12 citations
Semantic Scholar
Functional characteristics and therapeutic potential of SLC41 transporters.
Takayuki Nemoto, Hideaki Tagashira, T. Kita, S. Kita +1 more
2022Journal of Pharmacological Sciences11 citations Open access
Semantic Scholar
[Cardioprotective effect of the selective sigma-1 receptor agonist, SA4503].
K. Hirano, Hideaki Tagashira, K. Fukunaga
2014Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan9 citations Open access
Semantic Scholar
Sodium–calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia
Wakana Shoda, Naohiro Nomura, F. Ando, Hideaki Tagashira +8 more
2020PLoS ONE8 citations Open access
Semantic Scholar
[Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist].
Hideaki Tagashira, K. Fukunaga
2012Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan8 citations Open access
Semantic Scholar
Rivastigmine Restores 5-HT1A Receptor Levels in the Hippocampus of Olfactory Bulbectomized Mice
Muhammad Rashedul Islam, S. Moriguchi, Hideaki Tagashira, K. Fukunaga
20146 citations Open access
Semantic Scholar
Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment
Y. Fujita, Hideaki Tagashira, H. Hasegawa, K. Fukunaga +1 more
20146 citations
Semantic Scholar
Perineural treatment with anti-TNF-α antibody ameliorates persistent allodynia and edema in novel mouse models with complex regional pain syndrome.
Shiho Shibata, Hideaki Tagashira, Takayuki Nemoto, S. Kita +5 more
2023Journal of Pharmacological Sciences5 citations Open access
Semantic Scholar
Lymphangiogenesis and angiogenesis rescue murine ischemic hindlimb via transient receptor potential vanilloid 4.
Hideaki Yamada, Naoaki Sakata, Tomoko Tanaka, Hideaki Tagashira +5 more
2021Journal of Pharmacological Sciences4 citations Open access
Semantic Scholar
ALS‐related SIGMAR1 Missense Mutation Causes TDP‐43 Inclusion and Mitochondrial Injury
Yasuharu Shinoda, Hideaki Tagashira, K. Fukunaga
20153 citations
Semantic Scholar
Genetic knockout and pharmacologic inhibition of NCX1 attenuate hypoxia-induced pulmonary arterial hypertension.
Asahi Nagata, Hideaki Tagashira, S. Kita, T. Kita +4 more
2020Biochemical and Biophysical Research Communications - BBRC2 citations
Semantic Scholar
[Development of experimental techniques and evaluation to support evidence-based medicine (EBM)].
Hideaki Tagashira, T. Kobori
2013Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan2 citations Open access
Semantic Scholar
Correction: Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Efficacy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice
S. Moriguchi, Yasuharu Shinoda, Yui Yamamoto, Yuzuru Sasaki +3 more
2014PLoS ONE1 citations Open access
Semantic Scholar
Responsiveness to adenosine diphosphate on carotid arterial and platelet functions in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats
Hideaki Tagashira, K. Taguchi, Takayuki Nagano, Tsuneo Kobayashi +3 more
2026Purinergic Signalling Purinergic Signalling0 citations Open access
Semantic Scholar
Distal tubular NCX1 plays a critical role in ischemic acute kidney injury
Takayuki Nemoto, R. Wakasaki, Hideaki Tagashira, T. Kita +3 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Improvement effect of Eucommia ulmoides oliver derived geniposidic acid on hypoxia-induced pulmonary arterial hypertension
Wakana Tani, Mari Hida, Takuya Matsubara, Hideaki Tagashira +5 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Roles of vascular smooth muscle NCX1/2 in the development of pulmonary arterial hypertension
Takayuki Nemoto, Tomohiro Komatsu, T. Kita, Hideaki Tagashira +3 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Eucommia ulmoides oliver leaf extract and geniposidic acid improve hypoxia-induced pulmonary arterial hypertension
Wakana Tani, Mari Hida, Takuya Matsubara, Hideaki Tagashira +5 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
The regulation mechanisms of mitochondrial Ca2+ signaling mediated by cardiac Sigma-1 receptor
Hideaki Tagashira, Yasuharu Shinoda, T. Numata, K. Fukunaga
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Enhanced susceptibility to catecholamine-induced arrhythmias in CNNM2-deficient mice
Hideaki Tagashira, Takayuki Nemoto, T. Kita, S. Kita +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Therapeutic strategy targeting NCX1 for pulmonary arterial hypertension
S. Kita, Hideaki Tagashira, T. Iwamoto
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Involvement of mitochondrial Na+/Ca2+ exchanger in hypoxia-induced pulmonary arterial hypertension
S. Kita, Hideaki Tagashira, Mari Hida, Wakana Tani +3 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Localization analysis of several NCKX2-NCLX chimeras into plasma membrane/mitochondrial inner membrane
T. Nemoto, T. Kita, Hideaki Tagashira, S. Kita +1 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
The contribution of Na+/Ca2+ exchanger 1 in pulmonary arterial hypertension in mice.
S. Kita, Hideaki Tagashira, Asahi Nagata, T. Kita +1 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Functional role of NCX1 in brown adipose tissue thermogenesis
T. Kita, Hideaki Tagashira, T. Nemoto, S. Kita +1 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar

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K. Fukunaga×28
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K. Fukunaga — researcher profile on SciRah
T. Iwamoto×17
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S. Kita×15
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Yasuharu Shinoda×10
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S. Moriguchi — researcher profile on SciRah

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M. Bhuiyan — researcher profile on SciRah

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Takayuki Nemoto×7

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Yuzuru Sasaki×5

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T. Kita — researcher profile on SciRah