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Malene Winther · SciRah

Researcher profile · Semantic Scholar

Malene Winther

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Malene Winther — researcher profile on SciRah

h-index: 15
Works: 23
Citations: 617

Most-cited papers

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria.
C. Dahlgren, Michael Gabl, A. Holdfeldt, Malene Winther +1 more
2016Biochemical Pharmacology142 citations
Semantic Scholar
NCAM2/OCAM/RNCAM: cell adhesion molecule with a role in neuronal compartmentalization.
Malene Winther, V. Berezin, P. S. Walmod
2012International Journal of Biochemistry and Cell Biology50 citations
Semantic Scholar
CFP-10 from Mycobacterium tuberculosis Selectively Activates Human Neutrophils through a Pertussis Toxin-Sensitive Chemotactic Receptor
A. Welin, H. Björnsdóttir, Malene Winther, K. Christenson +5 more
2014Infection and Immunity46 citations Open access
Semantic Scholar
The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment
L. Björkman, J. Mårtensson, Malene Winther, Michael Gabl +8 more
2016Molecular and Cellular Biology45 citations Open access
Semantic Scholar
Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group.
H. Forsman, Malene Winther, Michael Gabl, S. L. Skovbakke +3 more
2015Biochimica et Biophysica Acta41 citations Open access
Semantic Scholar
Formyl Peptide Receptors in Mice and Men: Similarities and Differences in Recognition of Conventional Ligands and Modulating Lipopeptides.
Malene Winther, C. Dahlgren, H. Forsman
2018Basic & Clinical Pharmacology & Toxicology35 citations Open access
Semantic Scholar
P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism.
Michael Gabl, Malene Winther, A. Welin, A. Karlsson +4 more
2015Experimental Cell Research30 citations
Semantic Scholar
A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2
Michael Gabl, Malene Winther, S. L. Skovbakke, J. Bylund +2 more
2014PLoS ONE30 citations Open access
Semantic Scholar
A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead
Malene Winther, Michael Gabl, A. Welin, C. Dahlgren +1 more
2015FEBS Letters25 citations
Semantic Scholar
NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor
K. K. Rasmussen, Maria Hansen Falkesgaard, Malene Winther, N. K. Roed +10 more
2018Scientific Reports20 citations Open access
Semantic Scholar
The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase*
A. Holdfeldt, S. L. Skovbakke, Malene Winther, Michael Gabl +8 more
2016Journal of Biological Chemistry20 citations Open access
Semantic Scholar
A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.
Michael Gabl, A. Holdfeldt, Malene Winther, Tudor I. Oprea +3 more
2016Biochimica et Biophysica Acta20 citations Open access
Semantic Scholar
The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils.
S. L. Skovbakke, Malene Winther, Michael Gabl, A. Holdfeldt +5 more
2016Biochemical Pharmacology19 citations
Semantic Scholar
Antibacterial Activity of Pepducins, Allosterical Modulators of Formyl Peptide Receptor Signaling
Malene Winther, Michael Gabl, Tudor I. Oprea, Bodil Jönsson +4 more
2014Antimicrobial Agents and Chemotherapy17 citations Open access
Semantic Scholar
Neural cell adhesion molecules belonging to the family of leucine-rich repeat proteins.
Malene Winther, P. S. Walmod
2014Advances in neurobiology16 citations
Semantic Scholar
Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1
Malene Winther, A. Holdfeldt, Michael Gabl, Ji-Ming Wang +2 more
2016PLoS ONE14 citations Open access
Semantic Scholar
Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4
A. Holdfeldt, Malene Winther, Michael Gabl, C. Dahlgren +1 more
2016Data in Brief13 citations Open access
Semantic Scholar
Formyl peptide receptor 2 orchestrates mucosal protection against Citrobacter rodentium infection
S. Sharba, V. Venkatakrishnan, M. Padra, Malene Winther +5 more
2019Virulence12 citations Open access
Semantic Scholar
Turning chemoattractant receptors on and off with conventional ligands and allosteric modulators: recent advances in formyl peptide receptor signaling and regulation
J. Bylund, Michael Gabl, Malene Winther, Karin Önnheim +2 more
201412 citations Open access
Semantic Scholar
Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question
Malene Winther, A. Holdfeldt, M. Sundqvist, Z. Rajabkhani +4 more
2017PLoS ONE10 citations Open access
Semantic Scholar
Functional Modulation of the Pattern Recognition Formyl Peptide Receptors in Neutrophils - Lipopeptides - allosteric modulators of G-protein coupled receptors
Malene Winther
20170 citations
Semantic Scholar
Syddansk Universitet The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 ( GPR 43 ) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment
J. Mårtensson, Malene Winther, Michael Gabl, A. Holdfeldt +6 more
20160 citations
Semantic Scholar
Receptor Signaling Allosterical Modulators of Formyl Peptide Antibacterial Activity of Pepducins
H. Forsman, F. Boulay, J. Bylund, C. Dahlgren +3 more
20140 citations
Semantic Scholar

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C. Dahlgren×17
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Michael Gabl×17
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